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The map label for this gene is frr

Identifier: 78047031

GI number: 78047031

Start: 1657733

End: 1658290

Strand: Reverse

Name: frr

Synonym: XCV1475

Alternate gene names: 78047031

Gene position: 1658290-1657733 (Counterclockwise)

Preceding gene: 78047032

Following gene: 78047030

Centisome position: 32.02

GC content: 61.47

Gene sequence:

>558_bases
ATGCTCACCCAGATCAAACAAGACGCGCAGACGCGCATGACCAAGAGCATCGATGCTCTGCGCCATTCCCTCACCACCAT
CCGCACCGGCCGTGCCTCGCCGGCGCTGCTGGACGGTATCAAGGTCAAGGCCTACGGCGCCGATACGCCCCTGAATCAGG
TTGCCAGCATCAGCGTGTCCGAAGGCCGCTCGCTGGTCATCAGCCTGTTCGACAAGGGCATGATCAAGGACGTGGAAAAA
GCCATTTACGCTTCGGATCTGGGCCTGACCCCGACCGTGGTCGGCACCGTGATCCGCCTGAACCTGCCGCCGCTGACCGA
GGAGCGCCGCAAGGAGCTCAGCAAGTCCGTGCATGGCGAGGGCGAAGACAGCAAGGTCGCCATTCGCAACATCCGCCGCG
ACGCCAATCAGCAGGTCAAGGATCTGCTCAAGGACAAGGCCGTCACCGAAGACGAAGCCCGCAGCGCCGAGGACGATATC
CAGAAGCTCACCGACAAGGCCATCAAGGACGTGGATGAGGTCGTCAAGGGCAAGGAACAGGAATTGATGACGGTCTGA

Upstream 100 bases:

>100_bases
GCGCCAAGTGAACCGGCTGCGCGGGTGCTGACGGCCCGCGAGTCGTGAAACCCCAGTCCCGGCTATAATCCCCGGATTCA
GCTCCACACGGATTCCGGCG

Downstream 100 bases:

>100_bases
TCGTGGCATCGCCTGCCATGCATCCAGTCCCTTCTGCTGCTGTGCCGCGCCACATCGCCATCATCATGGATGGCAATGGG
CGTTGGGCGCAGCGTCGGCG

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MLTQIKQDAQTRMTKSIDALRHSLTTIRTGRASPALLDGIKVKAYGADTPLNQVASISVSEGRSLVISLFDKGMIKDVEK
AIYASDLGLTPTVVGTVIRLNLPPLTEERRKELSKSVHGEGEDSKVAIRNIRRDANQQVKDLLKDKAVTEDEARSAEDDI
QKLTDKAIKDVDEVVKGKEQELMTV

Sequences:

>Translated_185_residues
MLTQIKQDAQTRMTKSIDALRHSLTTIRTGRASPALLDGIKVKAYGADTPLNQVASISVSEGRSLVISLFDKGMIKDVEK
AIYASDLGLTPTVVGTVIRLNLPPLTEERRKELSKSVHGEGEDSKVAIRNIRRDANQQVKDLLKDKAVTEDEARSAEDDI
QKLTDKAIKDVDEVVKGKEQELMTV
>Mature_185_residues
MLTQIKQDAQTRMTKSIDALRHSLTTIRTGRASPALLDGIKVKAYGADTPLNQVASISVSEGRSLVISLFDKGMIKDVEK
AIYASDLGLTPTVVGTVIRLNLPPLTEERRKELSKSVHGEGEDSKVAIRNIRRDANQQVKDLLKDKAVTEDEARSAEDDI
QKLTDKAIKDVDEVVKGKEQELMTV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family

Homologues:

Organism=Homo sapiens, GI20270317, Length=174, Percent_Identity=29.3103448275862, Blast_Score=65, Evalue=3e-11,
Organism=Escherichia coli, GI1786368, Length=183, Percent_Identity=55.7377049180328, Blast_Score=212, Evalue=1e-56,
Organism=Drosophila melanogaster, GI24661488, Length=174, Percent_Identity=25.2873563218391, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): RRF_XANAC (Q8PMK8)

Other databases:

- EMBL:   AE008923
- RefSeq:   NP_641753.1
- ProteinModelPortal:   Q8PMK8
- SMR:   Q8PMK8
- GeneID:   1155489
- GenomeReviews:   AE008923_GR
- KEGG:   xac:XAC1418
- HOGENOM:   HBG533975
- OMA:   YYGAETP
- ProtClustDB:   PRK00083
- BioCyc:   XAXO190486:XAC1418-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00040
- InterPro:   IPR002661
- InterPro:   IPR015998
- PANTHER:   PTHR20982
- PANTHER:   PTHR20982:SF3
- TIGRFAMs:   TIGR00496

Pfam domain/function: PF01765 RRF; SSF55194 Ribosome_recyc_fac

EC number: NA

Molecular weight: Translated: 20353; Mature: 20353

Theoretical pI: Translated: 7.68; Mature: 7.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTQIKQDAQTRMTKSIDALRHSLTTIRTGRASPALLDGIKVKAYGADTPLNQVASISVS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCEEEEEECCCCCHHHHHHCCHH
EGRSLVISLFDKGMIKDVEKAIYASDLGLTPTVVGTVIRLNLPPLTEERRKELSKSVHGE
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHCCC
GEDSKVAIRNIRRDANQQVKDLLKDKAVTEDEARSAEDDIQKLTDKAIKDVDEVVKGKEQ
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCHHHHHHHHHHHHHHHHHHHHCCCHH
ELMTV
HHCCC
>Mature Secondary Structure
MLTQIKQDAQTRMTKSIDALRHSLTTIRTGRASPALLDGIKVKAYGADTPLNQVASISVS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCEEEEEECCCCCHHHHHHCCHH
EGRSLVISLFDKGMIKDVEKAIYASDLGLTPTVVGTVIRLNLPPLTEERRKELSKSVHGE
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHCCC
GEDSKVAIRNIRRDANQQVKDLLKDKAVTEDEARSAEDDIQKLTDKAIKDVDEVVKGKEQ
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCHHHHHHHHHHHHHHHHHHHHCCCHH
ELMTV
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217