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The map label for this gene is mhpF

Identifier: 78042871

GI number: 78042871

Start: 1139150

End: 1140049

Strand: Direct

Name: mhpF

Synonym: CHY_1279

Alternate gene names: 78042871

Gene position: 1139150-1140049 (Clockwise)

Preceding gene: 78042951

Following gene: 78044450

Centisome position: 47.43

GC content: 40.0

Gene sequence:

>900_bases
ATGTCGAACAAAATTAAAGCTGCCATTATCGGTCCTGGCAATATCGGGATGGATTTAATGTTTAAATTAATGAGAAGTAA
ATATATTGATGTTGACACAGTTGTTGGCATTATTCCGGAATCGGAAGGATTGGCATTGGCTAGAAAGCATGGAAAGAAGA
CTAGTGCTGAAGGAATAAAAGCAATTTTAGGAAATAAGGATATTAAAATCGTTTTTGATGCTACCAGTGCCAAAGCTCAT
TTAAAACACGCTCCTTTATTAGAACAAGATGGTAAAATTGCTATCGACCTGACACCTGCAGCAGTTGGTCCTTATTGTGT
TCCTGCAGTAACTATGGAGGAACAATTAAATTGCAAAAATGTTAATATGGTTACTTGTGCCGGACAAGCTACTACTCCAA
TTGTTTATGCAATTAACAAAATTGCCGATGTAAAATATGCTGAAATAGTAGCTACAATAAGTAGCCGGAGTGCTGGTCCA
GGAACGCGGCAGAATATTGACGAATTTACCGAAACTACGGCAAAAGCCCTGGAAAAAATTGGCGGGGCCGATAAAGGAAA
AGCAATAATTATTCTTAACCCGGCTGAACCGCCAATTATGATGCGAAACACTATTTACACCCGGGTAGCAAATCCGGATG
CTCCTGGAATTATCGAGGCAATTGAAGAAATGGTGGGGAAGATCAAAAAATACGTTCCTGGTTATCGCTTGAAAGTTCCT
CCAATCATTGATGGAGATAAGATTACCACAATAATTGAAGTTGAAGGTGAGGGGGCCTATTTGCCTAAATATGCCGGTAA
TCTTGATATAATCACCGCAGCAGCAGTAGCTTTTGCTGATGAAGTAGCTAAAAAGTTGCTGGCTGAGGAGCAAGCTAAGG
AGGTTAGAGCACATGGCTAA

Upstream 100 bases:

>100_bases
GTAATGACCATTTTGTTGCCAATTTCGGGCCTCTTGGTTCGGTTAAAGTAAAATTTACTGATTAACGATTAAAAATTAAT
ACGGCAAAGGAGTGAAGCAA

Downstream 100 bases:

>100_bases
AAAGATTAGGATAATTGACAGTACCTTAAGAGATGGAATGCATGCGGTAAGTCACCAGTTCACACCCGAGGAAATGGCAG
AAATTGCAGCAGGACTGGAT

Product: acetaldehyde dehydrogenase

Products: NA

Alternate protein names: Acetaldehyde dehydrogenase [acetylating]

Number of amino acids: Translated: 299; Mature: 298

Protein sequence:

>299_residues
MSNKIKAAIIGPGNIGMDLMFKLMRSKYIDVDTVVGIIPESEGLALARKHGKKTSAEGIKAILGNKDIKIVFDATSAKAH
LKHAPLLEQDGKIAIDLTPAAVGPYCVPAVTMEEQLNCKNVNMVTCAGQATTPIVYAINKIADVKYAEIVATISSRSAGP
GTRQNIDEFTETTAKALEKIGGADKGKAIIILNPAEPPIMMRNTIYTRVANPDAPGIIEAIEEMVGKIKKYVPGYRLKVP
PIIDGDKITTIIEVEGEGAYLPKYAGNLDIITAAAVAFADEVAKKLLAEEQAKEVRAHG

Sequences:

>Translated_299_residues
MSNKIKAAIIGPGNIGMDLMFKLMRSKYIDVDTVVGIIPESEGLALARKHGKKTSAEGIKAILGNKDIKIVFDATSAKAH
LKHAPLLEQDGKIAIDLTPAAVGPYCVPAVTMEEQLNCKNVNMVTCAGQATTPIVYAINKIADVKYAEIVATISSRSAGP
GTRQNIDEFTETTAKALEKIGGADKGKAIIILNPAEPPIMMRNTIYTRVANPDAPGIIEAIEEMVGKIKKYVPGYRLKVP
PIIDGDKITTIIEVEGEGAYLPKYAGNLDIITAAAVAFADEVAKKLLAEEQAKEVRAHG
>Mature_298_residues
SNKIKAAIIGPGNIGMDLMFKLMRSKYIDVDTVVGIIPESEGLALARKHGKKTSAEGIKAILGNKDIKIVFDATSAKAHL
KHAPLLEQDGKIAIDLTPAAVGPYCVPAVTMEEQLNCKNVNMVTCAGQATTPIVYAINKIADVKYAEIVATISSRSAGPG
TRQNIDEFTETTAKALEKIGGADKGKAIIILNPAEPPIMMRNTIYTRVANPDAPGIIEAIEEMVGKIKKYVPGYRLKVPP
IIDGDKITTIIEVEGEGAYLPKYAGNLDIITAAAVAFADEVAKKLLAEEQAKEVRAHG

Specific function: Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds

COG id: COG4569

COG function: function code Q; Acetaldehyde dehydrogenase (acetylating)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetaldehyde dehydrogenase family

Homologues:

Organism=Escherichia coli, GI1786547, Length=307, Percent_Identity=51.7915309446254, Blast_Score=290, Evalue=5e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACDH_CARHZ (Q3ACM1)

Other databases:

- EMBL:   CP000141
- RefSeq:   YP_360113.1
- ProteinModelPortal:   Q3ACM1
- SMR:   Q3ACM1
- STRING:   Q3ACM1
- GeneID:   3727086
- GenomeReviews:   CP000141_GR
- KEGG:   chy:CHY_1279
- NMPDR:   fig|246194.3.peg.1318
- TIGR:   CHY_1279
- eggNOG:   COG4569
- HOGENOM:   HBG300125
- OMA:   MIKVIRH
- ProtClustDB:   PRK08300
- BioCyc:   CHYD246194:CHY_1279-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01657
- InterPro:   IPR003361
- InterPro:   IPR015426
- InterPro:   IPR016040
- InterPro:   IPR000534
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR21123
- PIRSF:   PIRSF015689
- SMART:   SM00859
- TIGRFAMs:   TIGR03215

Pfam domain/function: PF09290 AcetDehyd-dimer; PF01118 Semialdhyde_dh

EC number: =1.2.1.10

Molecular weight: Translated: 31889; Mature: 31757

Theoretical pI: Translated: 8.04; Mature: 8.04

Prosite motif: NA

Important sites: BINDING 267-267

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNKIKAAIIGPGNIGMDLMFKLMRSKYIDVDTVVGIIPESEGLALARKHGKKTSAEGIK
CCCCEEEEEECCCCCCHHHHHHHHHHCCCCHHHEEEEEECCCCCHHHHHCCCCCHHHHHH
AILGNKDIKIVFDATSAKAHLKHAPLLEQDGKIAIDLTPAAVGPYCVPAVTMEEQLNCKN
HHHCCCCEEEEEECCCCHHHHCCCCCCCCCCCEEEEECCCCCCCEEECCCCHHHCCCCCC
VNMVTCAGQATTPIVYAINKIADVKYAEIVATISSRSAGPGTRQNIDEFTETTAKALEKI
CEEEEECCCCCCCHHEEHHHHCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
GGADKGKAIIILNPAEPPIMMRNTIYTRVANPDAPGIIEAIEEMVGKIKKYVPGYRLKVP
CCCCCCCEEEEECCCCCCEEEECEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCEEECC
PIIDGDKITTIIEVEGEGAYLPKYAGNLDIITAAAVAFADEVAKKLLAEEQAKEVRAHG
CEECCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SNKIKAAIIGPGNIGMDLMFKLMRSKYIDVDTVVGIIPESEGLALARKHGKKTSAEGIK
CCCEEEEEECCCCCCHHHHHHHHHHCCCCHHHEEEEEECCCCCHHHHHCCCCCHHHHHH
AILGNKDIKIVFDATSAKAHLKHAPLLEQDGKIAIDLTPAAVGPYCVPAVTMEEQLNCKN
HHHCCCCEEEEEECCCCHHHHCCCCCCCCCCCEEEEECCCCCCCEEECCCCHHHCCCCCC
VNMVTCAGQATTPIVYAINKIADVKYAEIVATISSRSAGPGTRQNIDEFTETTAKALEKI
CEEEEECCCCCCCHHEEHHHHCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
GGADKGKAIIILNPAEPPIMMRNTIYTRVANPDAPGIIEAIEEMVGKIKKYVPGYRLKVP
CCCCCCCEEEEECCCCCCEEEECEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCEEECC
PIIDGDKITTIIEVEGEGAYLPKYAGNLDIITAAAVAFADEVAKKLLAEEQAKEVRAHG
CEECCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA