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The map label for this gene is ubiB [C]

Identifier: 78042727

GI number: 78042727

Start: 1080715

End: 1082340

Strand: Direct

Name: ubiB [C]

Synonym: CHY_1218

Alternate gene names: 78042727

Gene position: 1080715-1082340 (Clockwise)

Preceding gene: 78044763

Following gene: 78043401

Centisome position: 45.0

GC content: 34.87

Gene sequence:

>1626_bases
GTGTTTCCTTTAACACCAAAGCACCTTTCAAGGTTTCGTGAAATTGCCCGTATTTTTACTGAATTTGGTTTTGGCTTTAT
TTTAACTTATTTAAAAAGGCCAGCAGCACTGGATAAAGTGGAAATCAACGAATACCGTTTAATTGAACTGGCCGGGAATT
TAAGGGAAATGTTAGAAAAATTAGGACCAACATTTATCAAACTTGGACAAGTTTTAAGTACGCAAAGAGACTTACTTCCC
AAGCCCTTTCAAGCTGAACTGGAAAAATTACAGGATAGAGTAACCCCGGTTCCTTTTGAAGTTATAGCTTCATATATTGA
GAAGAACTTGGGCTCTCCCCTGCACGATATCTTTATTGAGTTTGATGAAAATCCCATTGCCAGCGCTTCCATAGGGCAAG
TATACCGGGCCAAGCTTAAAAACGGAAAAAATGTGGTTGTAAAAGTAAAACGACCGGGGGTTGATGAACTGATTAAAACT
GACCTGCAAATTCTATATCAAATTGCTTCCTTTATTCAAAACAAAACCAACTGGGGAAAAATTAATAAACCTTTGCGAAT
GTGGGAAGAATTAAAATCAAGCTTGGAAAGGGAATTAGATTACACCGGGGAAGCACGGAATATAGAAAATTTCAGGCAAA
ATATAAAATATAAAAAACTAATTATTCCCGAAGTGTTCTGGAACTTTACCAATGAAAACATCTTAGTTTTAGAAGCGGTT
TACGGTATTAAAGTAAGTGAACGCTTCCAGCTAATTGAAATGGGTATCGATTTGGACCAGTTAGCTCGAGATTTAGTGGA
AATTTTTATTTTGCAGATTTTAGAAGACGGCTATTTTCATGCTGATCCCCATCCGGGCAACATTGCAATAACTCCGCTGG
GGGACATTATTTTGTATGACTTTGGGATGGTAGGTTTTTTAAATCCGTGGTTAAGGGAAATACTAATCACTTTATTAATA
AGTGTAGTAAGGAAGGATTTTGCAAGGATTTCCGAGTTATTAATTGAATTAAGTCAAAGACAAGACATAATTCCAGCGGA
AATAAAAAAAGATGTTCGGGAAATTTTAAATCGCTATTATTTCGTCCCATTATCTTCTTTATCGTTAGGAGAATTATTAA
AAGAGTTATTAAACCTTGCCCAAAAGCACGAAATAATAATTCCACCGGAAATTGTTTTAGTAGCGAAAACAATTATTGCT
TTAGAAGGAATAGTGAAGAATTTAAACAGTAACTTATCGGTAGCCGAATTAGCGGAGCCGTTAGCAACCAATCTTTTACG
GAAACGAATTTTTAAGTTTCCATCCTTTAAAAAAGTTGCCTTAGATTTATATAACTTAGTTGACAAGCTTTTTGCTTTGC
CAGGAATGTTAGAAAGTAGTTTAGCAAACTTAGAAAAAGCTAAATTCACTCTCAAAATAGAAGAACGTCAATTAGAAAGA
CAAGTAACTTCGTTTGCTAAAAGTATTCAGTTTTTAGCAATAGTTATCTTTTATGCAGCTTATTTTTTGGGTTCTCCGGC
AATTTTAAATGCTCTTCCGGCAGACCAGAAAGGTAAAATCTTTATTTTTATAACTGTTGTTTATTTTACCGGTGGGTACA
TTTTATGGAAAAAGCATCTGCTTTAG

Upstream 100 bases:

>100_bases
GAACTAAAGCTTTTAGAAAACCGCTTAAATGAATTAGAAAATAAAATCCAGGAACAAAACAGGGGGTAGCAACCCCTTGT
TTTTTTAAGGGGGATCAATT

Downstream 100 bases:

>100_bases
CATAGATTGTCCTCTTAGGGCATATTTTTTTTTAGAATAAACCCTAAGGGGGTAAGGGAGAATGTTAAAAAAATTTTTTA
AAGTAATAATTATTTTTCTT

Product: ABC1 family protein

Products: 2-octaprenyl-6-hydroxyphenol [C]

Alternate protein names: NA

Number of amino acids: Translated: 541; Mature: 541

Protein sequence:

>541_residues
MFPLTPKHLSRFREIARIFTEFGFGFILTYLKRPAALDKVEINEYRLIELAGNLREMLEKLGPTFIKLGQVLSTQRDLLP
KPFQAELEKLQDRVTPVPFEVIASYIEKNLGSPLHDIFIEFDENPIASASIGQVYRAKLKNGKNVVVKVKRPGVDELIKT
DLQILYQIASFIQNKTNWGKINKPLRMWEELKSSLERELDYTGEARNIENFRQNIKYKKLIIPEVFWNFTNENILVLEAV
YGIKVSERFQLIEMGIDLDQLARDLVEIFILQILEDGYFHADPHPGNIAITPLGDIILYDFGMVGFLNPWLREILITLLI
SVVRKDFARISELLIELSQRQDIIPAEIKKDVREILNRYYFVPLSSLSLGELLKELLNLAQKHEIIIPPEIVLVAKTIIA
LEGIVKNLNSNLSVAELAEPLATNLLRKRIFKFPSFKKVALDLYNLVDKLFALPGMLESSLANLEKAKFTLKIEERQLER
QVTSFAKSIQFLAIVIFYAAYFLGSPAILNALPADQKGKIFIFITVVYFTGGYILWKKHLL

Sequences:

>Translated_541_residues
MFPLTPKHLSRFREIARIFTEFGFGFILTYLKRPAALDKVEINEYRLIELAGNLREMLEKLGPTFIKLGQVLSTQRDLLP
KPFQAELEKLQDRVTPVPFEVIASYIEKNLGSPLHDIFIEFDENPIASASIGQVYRAKLKNGKNVVVKVKRPGVDELIKT
DLQILYQIASFIQNKTNWGKINKPLRMWEELKSSLERELDYTGEARNIENFRQNIKYKKLIIPEVFWNFTNENILVLEAV
YGIKVSERFQLIEMGIDLDQLARDLVEIFILQILEDGYFHADPHPGNIAITPLGDIILYDFGMVGFLNPWLREILITLLI
SVVRKDFARISELLIELSQRQDIIPAEIKKDVREILNRYYFVPLSSLSLGELLKELLNLAQKHEIIIPPEIVLVAKTIIA
LEGIVKNLNSNLSVAELAEPLATNLLRKRIFKFPSFKKVALDLYNLVDKLFALPGMLESSLANLEKAKFTLKIEERQLER
QVTSFAKSIQFLAIVIFYAAYFLGSPAILNALPADQKGKIFIFITVVYFTGGYILWKKHLL
>Mature_541_residues
MFPLTPKHLSRFREIARIFTEFGFGFILTYLKRPAALDKVEINEYRLIELAGNLREMLEKLGPTFIKLGQVLSTQRDLLP
KPFQAELEKLQDRVTPVPFEVIASYIEKNLGSPLHDIFIEFDENPIASASIGQVYRAKLKNGKNVVVKVKRPGVDELIKT
DLQILYQIASFIQNKTNWGKINKPLRMWEELKSSLERELDYTGEARNIENFRQNIKYKKLIIPEVFWNFTNENILVLEAV
YGIKVSERFQLIEMGIDLDQLARDLVEIFILQILEDGYFHADPHPGNIAITPLGDIILYDFGMVGFLNPWLREILITLLI
SVVRKDFARISELLIELSQRQDIIPAEIKKDVREILNRYYFVPLSSLSLGELLKELLNLAQKHEIIIPPEIVLVAKTIIA
LEGIVKNLNSNLSVAELAEPLATNLLRKRIFKFPSFKKVALDLYNLVDKLFALPGMLESSLANLEKAKFTLKIEERQLER
QVTSFAKSIQFLAIVIFYAAYFLGSPAILNALPADQKGKIFIFITVVYFTGGYILWKKHLL

Specific function: Required, Probably Indirectly, For The Hydroxylation Of 2-Octaprenylphenol To 2-Octaprenyl-6-Hydroxy-Phenol, The Fourth Step In Ubiquinone Biosynthesis. Specific For Aerobically Grown Log-Phase Cells. [C]

COG id: COG0661

COG function: function code R; Predicted unusual protein kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protein kinase superfamily. ADCK protein kinase family [H]

Homologues:

Organism=Homo sapiens, GI40254938, Length=295, Percent_Identity=29.8305084745763, Blast_Score=141, Evalue=2e-33,
Organism=Homo sapiens, GI41393593, Length=270, Percent_Identity=30, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI217035081, Length=325, Percent_Identity=27.6923076923077, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI34147522, Length=283, Percent_Identity=25.0883392226148, Blast_Score=86, Evalue=9e-17,
Organism=Homo sapiens, GI27363457, Length=271, Percent_Identity=25.0922509225092, Blast_Score=73, Evalue=9e-13,
Organism=Homo sapiens, GI217416386, Length=255, Percent_Identity=24.7058823529412, Blast_Score=66, Evalue=7e-11,
Organism=Escherichia coli, GI2367309, Length=521, Percent_Identity=30.1343570057582, Blast_Score=217, Evalue=2e-57,
Organism=Caenorhabditis elegans, GI17559152, Length=299, Percent_Identity=28.7625418060201, Blast_Score=124, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI32565180, Length=285, Percent_Identity=28.4210526315789, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17555620, Length=480, Percent_Identity=23.75, Blast_Score=79, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6325148, Length=495, Percent_Identity=25.8585858585859, Blast_Score=128, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6323282, Length=290, Percent_Identity=30.6896551724138, Blast_Score=112, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6321319, Length=249, Percent_Identity=29.3172690763052, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24662575, Length=251, Percent_Identity=32.2709163346614, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI22024280, Length=272, Percent_Identity=29.7794117647059, Blast_Score=120, Evalue=3e-27,
Organism=Drosophila melanogaster, GI18859849, Length=254, Percent_Identity=27.1653543307087, Blast_Score=86, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004147
- InterPro:   IPR011009
- InterPro:   IPR000719 [H]

Pfam domain/function: PF03109 ABC1 [H]

EC number: NA

Molecular weight: Translated: 62135; Mature: 62135

Theoretical pI: Translated: 9.08; Mature: 9.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFPLTPKHLSRFREIARIFTEFGFGFILTYLKRPAALDKVEINEYRLIELAGNLREMLEK
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCHHHHHHHHHHHHHHH
LGPTFIKLGQVLSTQRDLLPKPFQAELEKLQDRVTPVPFEVIASYIEKNLGSPLHDIFIE
HCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHEEE
FDENPIASASIGQVYRAKLKNGKNVVVKVKRPGVDELIKTDLQILYQIASFIQNKTNWGK
ECCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCC
INKPLRMWEELKSSLERELDYTGEARNIENFRQNIKYKKLIIPEVFWNFTNENILVLEAV
CCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCHHHHHHHHHHHCCCCCCEEEEEHH
YGIKVSERFQLIEMGIDLDQLARDLVEIFILQILEDGYFHADPHPGNIAITPLGDIILYD
HCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCEECCCCCCCEEEECCHHHHHHH
FGMVGFLNPWLREILITLLISVVRKDFARISELLIELSQRQDIIPAEIKKDVREILNRYY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHE
FVPLSSLSLGELLKELLNLAQKHEIIIPPEIVLVAKTIIALEGIVKNLNSNLSVAELAEP
ECCCCCCCHHHHHHHHHHHHHHCCEECCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
LATNLLRKRIFKFPSFKKVALDLYNLVDKLFALPGMLESSLANLEKAKFTLKIEERQLER
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHEEEEEHHHHHHH
QVTSFAKSIQFLAIVIFYAAYFLGSPAILNALPADQKGKIFIFITVVYFTGGYILWKKHL
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCEEEEEEEHHHHCCHHHHHHHC
L
C
>Mature Secondary Structure
MFPLTPKHLSRFREIARIFTEFGFGFILTYLKRPAALDKVEINEYRLIELAGNLREMLEK
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCHHHHHHHHHHHHHHH
LGPTFIKLGQVLSTQRDLLPKPFQAELEKLQDRVTPVPFEVIASYIEKNLGSPLHDIFIE
HCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHEEE
FDENPIASASIGQVYRAKLKNGKNVVVKVKRPGVDELIKTDLQILYQIASFIQNKTNWGK
ECCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCC
INKPLRMWEELKSSLERELDYTGEARNIENFRQNIKYKKLIIPEVFWNFTNENILVLEAV
CCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCHHHHHHHHHHHCCCCCCEEEEEHH
YGIKVSERFQLIEMGIDLDQLARDLVEIFILQILEDGYFHADPHPGNIAITPLGDIILYD
HCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCEECCCCCCCEEEECCHHHHHHH
FGMVGFLNPWLREILITLLISVVRKDFARISELLIELSQRQDIIPAEIKKDVREILNRYY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHE
FVPLSSLSLGELLKELLNLAQKHEIIIPPEIVLVAKTIIALEGIVKNLNSNLSVAELAEP
ECCCCCCCHHHHHHHHHHHHHHCCEECCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
LATNLLRKRIFKFPSFKKVALDLYNLVDKLFALPGMLESSLANLEKAKFTLKIEERQLER
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHEEEEEHHHHHHH
QVTSFAKSIQFLAIVIFYAAYFLGSPAILNALPADQKGKIFIFITVVYFTGGYILWKKHL
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCEEEEEEEHHHHCCHHHHHHHC
L
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2 2-octaprenylphenol; O2 [C]

Specific reaction: 2 2-octaprenylphenol + O2 = 2 2-octaprenyl-6-hydroxyphenol [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]