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The map label for this gene is 77748778

Identifier: 77748778

GI number: 77748778

Start: 5162937

End: 5163725

Strand: Direct

Name: 77748778

Synonym: XAC4366

Alternate gene names: NA

Gene position: 5162937-5163725 (Clockwise)

Preceding gene: 21245077

Following gene: 21245081

Centisome position: 99.76

GC content: 70.72

Gene sequence:

>789_bases
ATGACACCGCATCCTGTTGCCGCCGCCGACACCACCACCCAAGCTCGCCTGGATCGTTCCCGGGTCTTGCGTGCCTTCAA
TGTGAGCCTTGCCGCCGTGCTGCTGCTGGTGGCGGTGTTCACCGCCCAGGGCATGTTCGACTGGCGCGCCTGGGCGGTGG
CGCCGCTGCAGGCCGACGGCCTGCGCGGCATCCTCACCGCCCCGCTGCTGCATGGTTCGCTGGCCCACCTGGGCGCCAAC
GCCGCCGCGCTGCTGATCCTGGGCACGCTGGCCGGGAGCGTGTATCCGCGTGCCACCGTCATGGCGCTGCCGCTGCTGTG
GCTGGGCTCGGGCCTGGGCGCATGGCTGCTGGGCGAGCCCGGCAGCCGGCATCTGGGTGCCAGCGGCGTGACCCACGGGC
TGATGTTCCTGGTGTTCGTGCTGGGCCTGCTGCGCCGCGACCGCCCCGCGATCGCCACCAGCATGATCGCCTTCCTGTTC
TACGGCGGCATGCTGATGACCATCCTGCCGCACGAAGCCGGCGTGTCCTGGCAATCGCATCTGGGCGGTGCGGTGGCCGG
GTTGATCGCCGCCCTGCTGCTGCGCCTGCGCGACCCGCAACAGGCAAAGCCGCGCTACAGCTGGGAAGACGAGGACGAAG
ACGCTGCCTGGGACGTGAGCAACCCCGAGCACGCGATGCTGGAACCGCCACCGCCGCGTCAGGTGCCCGTGCTGTGGCAG
CGCCAGGACGATGGCTCGCAGAGCGTGGTGCTGCATTTCCCACCGCGCGAACGCCCGCCCGGTAGCTGA

Upstream 100 bases:

>100_bases
CCAGGATTCGGCGGCGGGATTGGATTATCCCGCCGCCGGGCCTGCTTATCCCGAGTTTGAGAGGCTTGTAAAAAACCCGC
GCGACGCCATTCGTGAAAGC

Downstream 100 bases:

>100_bases
GACGTTCCAGGCGGCCGCAGAACCGATCAATGCCCTGCCCTGCCCTGCCCCGCGTAGGCGCGTGCCTGCGCGCGATGGGC
TTTACCGATACAGCCCCGTC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 262; Mature: 261

Protein sequence:

>262_residues
MTPHPVAAADTTTQARLDRSRVLRAFNVSLAAVLLLVAVFTAQGMFDWRAWAVAPLQADGLRGILTAPLLHGSLAHLGAN
AAALLILGTLAGSVYPRATVMALPLLWLGSGLGAWLLGEPGSRHLGASGVTHGLMFLVFVLGLLRRDRPAIATSMIAFLF
YGGMLMTILPHEAGVSWQSHLGGAVAGLIAALLLRLRDPQQAKPRYSWEDEDEDAAWDVSNPEHAMLEPPPPRQVPVLWQ
RQDDGSQSVVLHFPPRERPPGS

Sequences:

>Translated_262_residues
MTPHPVAAADTTTQARLDRSRVLRAFNVSLAAVLLLVAVFTAQGMFDWRAWAVAPLQADGLRGILTAPLLHGSLAHLGAN
AAALLILGTLAGSVYPRATVMALPLLWLGSGLGAWLLGEPGSRHLGASGVTHGLMFLVFVLGLLRRDRPAIATSMIAFLF
YGGMLMTILPHEAGVSWQSHLGGAVAGLIAALLLRLRDPQQAKPRYSWEDEDEDAAWDVSNPEHAMLEPPPPRQVPVLWQ
RQDDGSQSVVLHFPPRERPPGS
>Mature_261_residues
TPHPVAAADTTTQARLDRSRVLRAFNVSLAAVLLLVAVFTAQGMFDWRAWAVAPLQADGLRGILTAPLLHGSLAHLGANA
AALLILGTLAGSVYPRATVMALPLLWLGSGLGAWLLGEPGSRHLGASGVTHGLMFLVFVLGLLRRDRPAIATSMIAFLFY
GGMLMTILPHEAGVSWQSHLGGAVAGLIAALLLRLRDPQQAKPRYSWEDEDEDAAWDVSNPEHAMLEPPPPRQVPVLWQR
QDDGSQSVVLHFPPRERPPGS

Specific function: Unknown

COG id: COG0705

COG function: function code R; Uncharacterized membrane protein (homolog of Drosophila rhomboid)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To M.leprae ML1171 [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022764 [H]

Pfam domain/function: PF01694 Rhomboid [H]

EC number: NA

Molecular weight: Translated: 28137; Mature: 28006

Theoretical pI: Translated: 7.38; Mature: 7.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPHPVAAADTTTQARLDRSRVLRAFNVSLAAVLLLVAVFTAQGMFDWRAWAVAPLQADG
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHEECCCCCCC
LRGILTAPLLHGSLAHLGANAAALLILGTLAGSVYPRATVMALPLLWLGSGLGAWLLGEP
CCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEECCC
GSRHLGASGVTHGLMFLVFVLGLLRRDRPAIATSMIAFLFYGGMLMTILPHEAGVSWQSH
CCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
LGGAVAGLIAALLLRLRDPQQAKPRYSWEDEDEDAAWDVSNPEHAMLEPPPPRQVPVLWQ
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEE
RQDDGSQSVVLHFPPRERPPGS
ECCCCCCEEEEECCCCCCCCCC
>Mature Secondary Structure 
TPHPVAAADTTTQARLDRSRVLRAFNVSLAAVLLLVAVFTAQGMFDWRAWAVAPLQADG
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHEECCCCCCC
LRGILTAPLLHGSLAHLGANAAALLILGTLAGSVYPRATVMALPLLWLGSGLGAWLLGEP
CCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEECCC
GSRHLGASGVTHGLMFLVFVLGLLRRDRPAIATSMIAFLFYGGMLMTILPHEAGVSWQSH
CCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
LGGAVAGLIAALLLRLRDPQQAKPRYSWEDEDEDAAWDVSNPEHAMLEPPPPRQVPVLWQ
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEE
RQDDGSQSVVLHFPPRERPPGS
ECCCCCCEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]