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The map label for this gene is yfkJ [H]

Identifier: 77465327

GI number: 77465327

Start: 389976

End: 390449

Strand: Reverse

Name: yfkJ [H]

Synonym: RSP_3326

Alternate gene names: 77465327

Gene position: 390449-389976 (Counterclockwise)

Preceding gene: 77465328

Following gene: 77465323

Centisome position: 41.4

GC content: 70.46

Gene sequence:

>474_bases
ATGAGTCTTCTTCCCTCCGTCCTCTTCGTCTGCCTCGGCAACATCTGCCGCTCGCCGCTCGCCGAGGCCGCCTTCCGCGC
CGCTGCGGACGAGCGCGGCCTCCGCCTCACCGTCGACAGCGCGGGCCTCGGCGGCTGGCATGCGGGCGAGGCGCCCGATC
CGCGCGCGCAGGAGGTGGCGCGCGCGAACGGCATCGACATCAGCCATTACCGCGCCCGTCAGGTGGCAAGGAAGGATTTC
GGCCTGTTCGATCATGTCGTGGCGCTCGACCTCGACAATCTGGTGGCGCTGCGCGAACTGCGCCCGCAGAGCGCCCGGGC
GCGACTGTCGCTCCTGCTCGACCATGTGCCGGGGCGGGAGGGACAGGCCGTGTCGGATCCCTATTACAGCGGTCCCGAAG
GGTTCCTCACCACCTGGTCGGATGTCACCGCCGGGGCGGACGGGCTGCTCACGAAGATCCTCGCCCCGGCCTGA

Upstream 100 bases:

>100_bases
AAGGCTCCGGCGCCATCCGGGCCACGGCGCGCGCGCGGCGCAACCTCTTGAGGCCGTTTCGGGATCCACCTAGGCTCGCC
CCGTTCTGTTCGAGGTAACC

Downstream 100 bases:

>100_bases
GCCGCGGCGCCGCTCAGGCGTCGGCGGGCAGGCGGCGGCGCAGAGGCAGCCGCTCGCCCGCAAGCCGCCAGCCCTCGCGC
AGGGTCTGGCGGCCCGAGGC

Product: protein tyrosine phosphatase

Products: NA

Alternate protein names: LMPTP [H]

Number of amino acids: Translated: 157; Mature: 156

Protein sequence:

>157_residues
MSLLPSVLFVCLGNICRSPLAEAAFRAAADERGLRLTVDSAGLGGWHAGEAPDPRAQEVARANGIDISHYRARQVARKDF
GLFDHVVALDLDNLVALRELRPQSARARLSLLLDHVPGREGQAVSDPYYSGPEGFLTTWSDVTAGADGLLTKILAPA

Sequences:

>Translated_157_residues
MSLLPSVLFVCLGNICRSPLAEAAFRAAADERGLRLTVDSAGLGGWHAGEAPDPRAQEVARANGIDISHYRARQVARKDF
GLFDHVVALDLDNLVALRELRPQSARARLSLLLDHVPGREGQAVSDPYYSGPEGFLTTWSDVTAGADGLLTKILAPA
>Mature_156_residues
SLLPSVLFVCLGNICRSPLAEAAFRAAADERGLRLTVDSAGLGGWHAGEAPDPRAQEVARANGIDISHYRARQVARKDFG
LFDHVVALDLDNLVALRELRPQSARARLSLLLDHVPGREGQAVSDPYYSGPEGFLTTWSDVTAGADGLLTKILAPA

Specific function: Dephosphorylates the phosphotyrosine-containing proteins. Involved in ethanol stress resistance [H]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase family [H]

Homologues:

Organism=Homo sapiens, GI6005988, Length=151, Percent_Identity=37.0860927152318, Blast_Score=110, Evalue=4e-25,
Organism=Homo sapiens, GI4757714, Length=151, Percent_Identity=37.7483443708609, Blast_Score=106, Evalue=7e-24,
Organism=Homo sapiens, GI96304457, Length=79, Percent_Identity=49.3670886075949, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6325330, Length=154, Percent_Identity=31.1688311688312, Blast_Score=105, Evalue=3e-24,
Organism=Drosophila melanogaster, GI78706766, Length=154, Percent_Identity=35.7142857142857, Blast_Score=115, Evalue=1e-26,
Organism=Drosophila melanogaster, GI78706768, Length=154, Percent_Identity=35.7142857142857, Blast_Score=115, Evalue=1e-26,
Organism=Drosophila melanogaster, GI78706764, Length=128, Percent_Identity=38.28125, Blast_Score=107, Evalue=3e-24,
Organism=Drosophila melanogaster, GI78706770, Length=150, Percent_Identity=37.3333333333333, Blast_Score=97, Evalue=5e-21,
Organism=Drosophila melanogaster, GI78706772, Length=150, Percent_Identity=37.3333333333333, Blast_Score=97, Evalue=5e-21,
Organism=Drosophila melanogaster, GI78711846, Length=150, Percent_Identity=33.3333333333333, Blast_Score=93, Evalue=7e-20,
Organism=Drosophila melanogaster, GI24648069, Length=87, Percent_Identity=40.2298850574713, Blast_Score=76, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000106
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 16801; Mature: 16670

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLLPSVLFVCLGNICRSPLAEAAFRAAADERGLRLTVDSAGLGGWHAGEAPDPRAQEVA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCHHHHHHH
RANGIDISHYRARQVARKDFGLFDHVVALDLDNLVALRELRPQSARARLSLLLDHVPGRE
HHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCC
GQAVSDPYYSGPEGFLTTWSDVTAGADGLLTKILAPA
CCCCCCCCCCCCCCCEECCHHHHCCHHHHHHHHHCCC
>Mature Secondary Structure 
SLLPSVLFVCLGNICRSPLAEAAFRAAADERGLRLTVDSAGLGGWHAGEAPDPRAQEVA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCHHHHHHH
RANGIDISHYRARQVARKDFGLFDHVVALDLDNLVALRELRPQSARARLSLLLDHVPGRE
HHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCC
GQAVSDPYYSGPEGFLTTWSDVTAGADGLLTKILAPA
CCCCCCCCCCCCCCCEECCHHHHCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]