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The map label for this gene is acoR [H]

Identifier: 77465323

GI number: 77465323

Start: 383049

End: 384884

Strand: Reverse

Name: acoR [H]

Synonym: RSP_3322

Alternate gene names: 77465323

Gene position: 384884-383049 (Counterclockwise)

Preceding gene: 77465327

Following gene: 77465322

Centisome position: 40.81

GC content: 73.69

Gene sequence:

>1836_bases
ATGGAGCACGAGCTCAGCCATGTGCGCGAGATCGAGGCTGCGGCCGAAGGGCGGCCGCCCGGGCGCGACCGGGTGGTGGT
CGAAAGCTGGCTCCGCTGCCTGAACCAGCATCGGCTCGATCCGACCGCCCGGTCCGAGGCCTTCATCCTGCCCGAGACGG
CGCTGCGCGAGCATCGCCAGCGGTCCGAGGCGCTGATCGCCATCGCCCGGTCGGGGATCGAGAGCCTCTACGGGCTGGTC
GCGGGGCAGAATTACGTCCTGCTGCTTGCGGACCGGGCCGGGGTGACGGTGGAATATCTGGGCGACGAGGCCCAGAAGCA
GGAACTGCGCCGGAGCGGTCTCTATATGGGCGCCGAATGGTCCGAGGCGCGCGCGGGCACCTGCGCGCTCGGCGCCTGCA
TCGAGACGGGCGAGCCGCTGGTGATCCACCAGAGCGATCATTTCGACGCGACGCACACCGGCCTCTCCTGCACCGCCGCG
CCGATCTACGACACGCTCGGCCGGCTCTCGGCGGTGCTCGACATCTCGCTTCTCTCCTCGCCGCGCGCGAAGGCGAGCCA
GTCGCTGGCGCTGAAGCTGGTGACGGCGGCGGCGCGGCGGATCGAGATGGCGAACCTGATGGCCGAGAACCGACGCGAAT
GGGTGCTCCGGCTCTCGGCCTCGCCGGATTTCCTCGATGTGGATCCCGAGGCGGCGCTGTCGCTCGACGGGACGGGGCGG
GTGCTGGGGCTGACCCATGGCGCCGCACGGATCCTCGCGCAGGCGGCGGGGCAGGACTGGCGCGCGGCGGGCGGGCTGAT
CGGGCGGCCGGTCTCGGATTTCCTGAACGTGCGGGTGGACCGGCTCGACGATCTCATGCGCCAGCGCCCCGCAGCCGAGC
GGTTCATCGAGACGCGCGACGGCCACCGGCTCTTCGCCCATGCGATCGAACCGCGCCGCGCGCCTGCCCGGACGGTGCCC
GCGCCGGTGAGCCTGCCGCCGCCGCTGCGAGGCCTTGCCGGCGACGATCCAACGATGGCCGCGCTCCTGCGGGCGGCCGC
GGCCCTTGCGCCGCAGCGGCTGCCGATCCTGATCGAGGGCGAGACCGGCACGGGCAAGCTCACGCTCGCCCGCGCGATCC
ATGCGGCGGGGCGCGGCGGGCCCTTCACGGTGGTGCGCTGCGCCGAGATCGGCGAGGAGGAGGCGCTGCTCTTCGGCCGC
CAGACCGGGCGGCGGCAGGAAGAGGGGCTGATCGCTGCCGCCCATCGCGGCACGCTCGTCCTCGACAAGATCGAGGATCT
GCCGCCCCGCACGCAGGCGCGCCTTCTGCGCCTGGTGGCCGAGGGCAGCTACCTGCCGGTGGGCGGCCTGCGCCCGGTGC
CGGTCGACGTGCGCATCCTTTCGACCGCGCTGCCGGGCGGGGCCGAGGGGCTGCGGCCCGACCTCCTGCACCGGCTGGGC
GGGGCGTGGCTGCGGCTGCCGCCGCTGCGGGCGCGACAGGACCGGCTGTGGCTGGCCGAGCGGCTGCTCGGCTCGGGCGA
CCGGCCGCTCTCGCTTGCGCCCGAGGCGCTGGCGGTGCTGGCCTCGCATCTCTGGCCCGGCAATCTGCGCGAACTCGAGC
ATATGGCGCAGACGCTGCGGGCCCTGGTGCCGGGCGCTGAGGTCGGCCTCGCCGATCTGCCGGAGACGATCCGGGCGGGG
ACCGCGTCCGGCCCAGGCGTCCCGCAGGCGGCAGGGGCGGTGCTGGCTCAGGTGCTGCGCCAGACCGGGGGCAATGTCTC
CGAAGCCGCGCGACGGCTGGGCGTCAATCGCTCGACAATTCATCGCCAGATCCGCCGAATGGGCGTGACACGCTGA

Upstream 100 bases:

>100_bases
CTGCGGCAGGCTCTGGCCTAAAGCCTTATTTCGCCCTCTCCCGTCCTTCCGCTACCATCTGTCCGGACGGGCTTGGGAGG
GCCCTGGGGGAGGGACCAGC

Downstream 100 bases:

>100_bases
AAAGGCGGGCGTTCGCGGTCATCCTGCACGCAGGTGCTTGACTTTGGAAACTGGTTGGTTTCCTAAGCAGGCCACCGCTG
CCGATGGAGTCTGCCCGTGA

Product: acetoin transcriptional regulator, sigma54 specific, AcoR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 611; Mature: 611

Protein sequence:

>611_residues
MEHELSHVREIEAAAEGRPPGRDRVVVESWLRCLNQHRLDPTARSEAFILPETALREHRQRSEALIAIARSGIESLYGLV
AGQNYVLLLADRAGVTVEYLGDEAQKQELRRSGLYMGAEWSEARAGTCALGACIETGEPLVIHQSDHFDATHTGLSCTAA
PIYDTLGRLSAVLDISLLSSPRAKASQSLALKLVTAAARRIEMANLMAENRREWVLRLSASPDFLDVDPEAALSLDGTGR
VLGLTHGAARILAQAAGQDWRAAGGLIGRPVSDFLNVRVDRLDDLMRQRPAAERFIETRDGHRLFAHAIEPRRAPARTVP
APVSLPPPLRGLAGDDPTMAALLRAAAALAPQRLPILIEGETGTGKLTLARAIHAAGRGGPFTVVRCAEIGEEEALLFGR
QTGRRQEEGLIAAAHRGTLVLDKIEDLPPRTQARLLRLVAEGSYLPVGGLRPVPVDVRILSTALPGGAEGLRPDLLHRLG
GAWLRLPPLRARQDRLWLAERLLGSGDRPLSLAPEALAVLASHLWPGNLRELEHMAQTLRALVPGAEVGLADLPETIRAG
TASGPGVPQAAGAVLAQVLRQTGGNVSEAARRLGVNRSTIHRQIRRMGVTR

Sequences:

>Translated_611_residues
MEHELSHVREIEAAAEGRPPGRDRVVVESWLRCLNQHRLDPTARSEAFILPETALREHRQRSEALIAIARSGIESLYGLV
AGQNYVLLLADRAGVTVEYLGDEAQKQELRRSGLYMGAEWSEARAGTCALGACIETGEPLVIHQSDHFDATHTGLSCTAA
PIYDTLGRLSAVLDISLLSSPRAKASQSLALKLVTAAARRIEMANLMAENRREWVLRLSASPDFLDVDPEAALSLDGTGR
VLGLTHGAARILAQAAGQDWRAAGGLIGRPVSDFLNVRVDRLDDLMRQRPAAERFIETRDGHRLFAHAIEPRRAPARTVP
APVSLPPPLRGLAGDDPTMAALLRAAAALAPQRLPILIEGETGTGKLTLARAIHAAGRGGPFTVVRCAEIGEEEALLFGR
QTGRRQEEGLIAAAHRGTLVLDKIEDLPPRTQARLLRLVAEGSYLPVGGLRPVPVDVRILSTALPGGAEGLRPDLLHRLG
GAWLRLPPLRARQDRLWLAERLLGSGDRPLSLAPEALAVLASHLWPGNLRELEHMAQTLRALVPGAEVGLADLPETIRAG
TASGPGVPQAAGAVLAQVLRQTGGNVSEAARRLGVNRSTIHRQIRRMGVTR
>Mature_611_residues
MEHELSHVREIEAAAEGRPPGRDRVVVESWLRCLNQHRLDPTARSEAFILPETALREHRQRSEALIAIARSGIESLYGLV
AGQNYVLLLADRAGVTVEYLGDEAQKQELRRSGLYMGAEWSEARAGTCALGACIETGEPLVIHQSDHFDATHTGLSCTAA
PIYDTLGRLSAVLDISLLSSPRAKASQSLALKLVTAAARRIEMANLMAENRREWVLRLSASPDFLDVDPEAALSLDGTGR
VLGLTHGAARILAQAAGQDWRAAGGLIGRPVSDFLNVRVDRLDDLMRQRPAAERFIETRDGHRLFAHAIEPRRAPARTVP
APVSLPPPLRGLAGDDPTMAALLRAAAALAPQRLPILIEGETGTGKLTLARAIHAAGRGGPFTVVRCAEIGEEEALLFGR
QTGRRQEEGLIAAAHRGTLVLDKIEDLPPRTQARLLRLVAEGSYLPVGGLRPVPVDVRILSTALPGGAEGLRPDLLHRLG
GAWLRLPPLRARQDRLWLAERLLGSGDRPLSLAPEALAVLASHLWPGNLRELEHMAQTLRALVPGAEVGLADLPETIRAG
TASGPGVPQAAGAVLAQVLRQTGGNVSEAARRLGVNRSTIHRQIRRMGVTR

Specific function: Required for sigma-54-dependent transcription of acoXABC [H]

COG id: COG3284

COG function: function code QK; Transcriptional activator of acetoin/glycerol metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1789233, Length=346, Percent_Identity=32.6589595375723, Blast_Score=151, Evalue=2e-37,
Organism=Escherichia coli, GI87081858, Length=637, Percent_Identity=24.8037676609105, Blast_Score=141, Evalue=2e-34,
Organism=Escherichia coli, GI1790299, Length=341, Percent_Identity=32.5513196480938, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1790437, Length=307, Percent_Identity=32.8990228013029, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI1788550, Length=309, Percent_Identity=31.0679611650485, Blast_Score=134, Evalue=2e-32,
Organism=Escherichia coli, GI1786524, Length=320, Percent_Identity=36.25, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1788905, Length=294, Percent_Identity=32.9931972789116, Blast_Score=123, Evalue=3e-29,
Organism=Escherichia coli, GI1787583, Length=303, Percent_Identity=32.3432343234323, Blast_Score=117, Evalue=3e-27,
Organism=Escherichia coli, GI87082117, Length=312, Percent_Identity=33.0128205128205, Blast_Score=115, Evalue=7e-27,
Organism=Escherichia coli, GI1789087, Length=314, Percent_Identity=31.5286624203822, Blast_Score=109, Evalue=4e-25,
Organism=Escherichia coli, GI87082152, Length=316, Percent_Identity=33.2278481012658, Blast_Score=102, Evalue=1e-22,
Organism=Escherichia coli, GI87081872, Length=228, Percent_Identity=33.7719298245614, Blast_Score=100, Evalue=5e-22,
Organism=Escherichia coli, GI1789828, Length=231, Percent_Identity=32.4675324675325, Blast_Score=79, Evalue=1e-15,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 65773; Mature: 65773

Theoretical pI: Translated: 9.00; Mature: 9.00

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEHELSHVREIEAAAEGRPPGRDRVVVESWLRCLNQHRLDPTARSEAFILPETALREHRQ
CCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEECCHHHHHHHHH
RSEALIAIARSGIESLYGLVAGQNYVLLLADRAGVTVEYLGDEAQKQELRRSGLYMGAEW
HHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEECCCHHHHHHHHHCCCEECCCC
SEARAGTCALGACIETGEPLVIHQSDHFDATHTGLSCTAAPIYDTLGRLSAVLDISLLSS
CCCCCCHHHHHHHHCCCCEEEEECCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHCC
PRAKASQSLALKLVTAAARRIEMANLMAENRREWVLRLSASPDFLDVDPEAALSLDGTGR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCEECCCCCEEEECCCCC
VLGLTHGAARILAQAAGQDWRAAGGLIGRPVSDFLNVRVDRLDDLMRQRPAAERFIETRD
EEEECHHHHHHHHHHCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHCCC
GHRLFAHAIEPRRAPARTVPAPVSLPPPLRGLAGDDPTMAALLRAAAALAPQRLPILIEG
CCEEHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEC
ETGTGKLTLARAIHAAGRGGPFTVVRCAEIGEEEALLFGRQTGRRQEEGLIAAAHRGTLV
CCCCCHHHHHHHHHHCCCCCCEEEEEEHHCCCHHHHHHCHHCCCCCCCCEEEEECCCCEE
LDKIEDLPPRTQARLLRLVAEGSYLPVGGLRPVPVDVRILSTALPGGAEGLRPDLLHRLG
EEHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCHHHHHHCC
GAWLRLPPLRARQDRLWLAERLLGSGDRPLSLAPEALAVLASHLWPGNLRELEHMAQTLR
CCEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHH
ALVPGAEVGLADLPETIRAGTASGPGVPQAAGAVLAQVLRQTGGNVSEAARRLGVNRSTI
HHCCCCCCCHHHCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHH
HRQIRRMGVTR
HHHHHHHCCCC
>Mature Secondary Structure
MEHELSHVREIEAAAEGRPPGRDRVVVESWLRCLNQHRLDPTARSEAFILPETALREHRQ
CCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEECCHHHHHHHHH
RSEALIAIARSGIESLYGLVAGQNYVLLLADRAGVTVEYLGDEAQKQELRRSGLYMGAEW
HHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEECCCHHHHHHHHHCCCEECCCC
SEARAGTCALGACIETGEPLVIHQSDHFDATHTGLSCTAAPIYDTLGRLSAVLDISLLSS
CCCCCCHHHHHHHHCCCCEEEEECCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHCC
PRAKASQSLALKLVTAAARRIEMANLMAENRREWVLRLSASPDFLDVDPEAALSLDGTGR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCEECCCCCEEEECCCCC
VLGLTHGAARILAQAAGQDWRAAGGLIGRPVSDFLNVRVDRLDDLMRQRPAAERFIETRD
EEEECHHHHHHHHHHCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHCCC
GHRLFAHAIEPRRAPARTVPAPVSLPPPLRGLAGDDPTMAALLRAAAALAPQRLPILIEG
CCEEHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEC
ETGTGKLTLARAIHAAGRGGPFTVVRCAEIGEEEALLFGRQTGRRQEEGLIAAAHRGTLV
CCCCCHHHHHHHHHHCCCCCCEEEEEEHHCCCHHHHHHCHHCCCCCCCCEEEEECCCCEE
LDKIEDLPPRTQARLLRLVAEGSYLPVGGLRPVPVDVRILSTALPGGAEGLRPDLLHRLG
EEHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCHHHHHHCC
GAWLRLPPLRARQDRLWLAERLLGSGDRPLSLAPEALAVLASHLWPGNLRELEHMAQTLR
CCEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHH
ALVPGAEVGLADLPETIRAGTASGPGVPQAAGAVLAQVLRQTGGNVSEAARRLGVNRSTI
HHCCCCCCCHHHCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHH
HRQIRRMGVTR
HHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1378052 [H]