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The map label for this gene is pheC [H]

Identifier: 77460036

GI number: 77460036

Start: 4314718

End: 4315572

Strand: Direct

Name: pheC [H]

Synonym: Pfl01_3814

Alternate gene names: 77460036

Gene position: 4314718-4315572 (Clockwise)

Preceding gene: 77460035

Following gene: 77460039

Centisome position: 67.02

GC content: 60.47

Gene sequence:

>855_bases
ATGACACCCGGCAAACCCATTCACTACACTGGCCCGCACCTCCACTGCACAAGCCCGATCTCCATGACAATTCGAAAAAG
CACGATGATCTTCTGCGGCCTGCTGGCCATGGCCGGCGCCGCCCAGGCACAAGAACCGGCCTCGCACCTCGACACCATTC
AGCAACAGGGCCAGTTGCGCGTCTGCACCACCGGCGACTACAAGCCCTACACCTTCAAACGCCCGGACGGCGGATTCGAA
GGCATCGACATCGCCATGGCGCAAACCCTGGCCGACAGCCTCGGCGTCAAGGTCGAATGGGTGCAGACCACCTGGAAAAC
CCTGATGCCGGACATGCAGGCCGGCAAATGCGACATCGGCGTTGGCGGCATTTCGGTGACCCTCGAACGCCAGAAAAAAG
CCTTCTTCAGCAACACCCTCGACGTCGACGGCAAGATCCCGCTGGTGCGCTGCGCCGACCAGTCCAAATACCAGACCATC
GACCAGATCAACCAGCCGAACGTGCGCCTGGTCGAACCCGCCGGCGGCACCAACGAAGCCTTCGTCCACGCCTTCCTGCC
CAAGGCGCAACTGGCGTTGCACGACAACGTGACCATCTTTGAACAACTGCTCGACAACAAGGCCGACGTGATGATCACCG
ACGCCTCCGAAGCCCTCTACCAACAAAAACTCAAACCCGGCCTGTGCGCCGTCAACCCGAGCCAGTTCATGCAATACGGC
GAAAAAGCCTACCTGCTGCCGCGCGACGACATCAGCTGGAAACTCTACGTCGACCAGTGGCTGCACCTGAGCAAAGTCAC
CGGCAAATACCAGAAAGTCCTGAGCGAATGGATCGCCGTACCCGCGGCCCAGTAA

Upstream 100 bases:

>100_bases
CGGCCAATGCTCTGCGGCGCAGTGTTGCAGTGGAGCTGGGCATCGCGCTGTTGATCGTGGCGCTGGTGGCGTGGCTGGGC
ACACTTGGGCCGGACGCGGG

Downstream 100 bases:

>100_bases
CCCTCAATCGTCATGCATCAGGCCGGAGCTGTACTGGTTGAAACTGTTACCGATATTGCTCCCGCCAAACTTCAACGTAT
TCACGTTCCGCGCCTCCGGC

Product: cyclohexadienyl dehydratase

Products: NA

Alternate protein names: Prephenate dehydratase; Arogenate dehydratase [H]

Number of amino acids: Translated: 284; Mature: 283

Protein sequence:

>284_residues
MTPGKPIHYTGPHLHCTSPISMTIRKSTMIFCGLLAMAGAAQAQEPASHLDTIQQQGQLRVCTTGDYKPYTFKRPDGGFE
GIDIAMAQTLADSLGVKVEWVQTTWKTLMPDMQAGKCDIGVGGISVTLERQKKAFFSNTLDVDGKIPLVRCADQSKYQTI
DQINQPNVRLVEPAGGTNEAFVHAFLPKAQLALHDNVTIFEQLLDNKADVMITDASEALYQQKLKPGLCAVNPSQFMQYG
EKAYLLPRDDISWKLYVDQWLHLSKVTGKYQKVLSEWIAVPAAQ

Sequences:

>Translated_284_residues
MTPGKPIHYTGPHLHCTSPISMTIRKSTMIFCGLLAMAGAAQAQEPASHLDTIQQQGQLRVCTTGDYKPYTFKRPDGGFE
GIDIAMAQTLADSLGVKVEWVQTTWKTLMPDMQAGKCDIGVGGISVTLERQKKAFFSNTLDVDGKIPLVRCADQSKYQTI
DQINQPNVRLVEPAGGTNEAFVHAFLPKAQLALHDNVTIFEQLLDNKADVMITDASEALYQQKLKPGLCAVNPSQFMQYG
EKAYLLPRDDISWKLYVDQWLHLSKVTGKYQKVLSEWIAVPAAQ
>Mature_283_residues
TPGKPIHYTGPHLHCTSPISMTIRKSTMIFCGLLAMAGAAQAQEPASHLDTIQQQGQLRVCTTGDYKPYTFKRPDGGFEG
IDIAMAQTLADSLGVKVEWVQTTWKTLMPDMQAGKCDIGVGGISVTLERQKKAFFSNTLDVDGKIPLVRCADQSKYQTID
QINQPNVRLVEPAGGTNEAFVHAFLPKAQLALHDNVTIFEQLLDNKADVMITDASEALYQQKLKPGLCAVNPSQFMQYGE
KAYLLPRDDISWKLYVDQWLHLSKVTGKYQKVLSEWIAVPAAQ

Specific function: Forms alternative pathway for phenylalanine biosynthesis. Can catalyze two reactions:prephenate dehydratase and arogenate dehydratase. May have a role in chemotaxis or transport [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 3 family [H]

Homologues:

Organism=Escherichia coli, GI1788228, Length=189, Percent_Identity=25.3968253968254, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: 1920 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1060 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 80 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015683
- InterPro:   IPR001638
- InterPro:   IPR018313 [H]

Pfam domain/function: PF00497 SBP_bac_3 [H]

EC number: =4.2.1.51; =4.2.1.91 [H]

Molecular weight: Translated: 31430; Mature: 31299

Theoretical pI: Translated: 7.15; Mature: 7.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPGKPIHYTGPHLHCTSPISMTIRKSTMIFCGLLAMAGAAQAQEPASHLDTIQQQGQLR
CCCCCCEEECCCCEEECCCCEEEEHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCEE
VCTTGDYKPYTFKRPDGGFEGIDIAMAQTLADSLGVKVEWVQTTWKTLMPDMQAGKCDIG
EEECCCCCCCEEECCCCCCCCHHHHHHHHHHHHHCCEEEEHHHHHHHHCCCCCCCCEEEE
VGGISVTLERQKKAFFSNTLDVDGKIPLVRCADQSKYQTIDQINQPNVRLVEPAGGTNEA
CCCEEEEEEHHHHHHHHCCCCCCCCCCEEEECCCCHHHHHHHCCCCCEEEECCCCCCCCC
FVHAFLPKAQLALHDNVTIFEQLLDNKADVMITDASEALYQQKLKPGLCAVNPSQFMQYG
EEEEECCCCEEEECCCHHHHHHHHCCCCCEEEECHHHHHHHHHCCCCCEEECHHHHHHCC
EKAYLLPRDDISWKLYVDQWLHLSKVTGKYQKVLSEWIAVPAAQ
CEEEEECCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TPGKPIHYTGPHLHCTSPISMTIRKSTMIFCGLLAMAGAAQAQEPASHLDTIQQQGQLR
CCCCCEEECCCCEEECCCCEEEEHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCEE
VCTTGDYKPYTFKRPDGGFEGIDIAMAQTLADSLGVKVEWVQTTWKTLMPDMQAGKCDIG
EEECCCCCCCEEECCCCCCCCHHHHHHHHHHHHHCCEEEEHHHHHHHHCCCCCCCCEEEE
VGGISVTLERQKKAFFSNTLDVDGKIPLVRCADQSKYQTIDQINQPNVRLVEPAGGTNEA
CCCEEEEEEHHHHHHHHCCCCCCCCCCEEEECCCCHHHHHHHCCCCCEEEECCCCCCCCC
FVHAFLPKAQLALHDNVTIFEQLLDNKADVMITDASEALYQQKLKPGLCAVNPSQFMQYG
EEEEECCCCEEEECCCHHHHHHHHCCCCCEEEECHHHHHHHHHCCCCCEEECHHHHHHCC
EKAYLLPRDDISWKLYVDQWLHLSKVTGKYQKVLSEWIAVPAAQ
CEEEEECCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1733946; 10984043; 8515238; 7604006 [H]