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The map label for this gene is cmpR [H]

Identifier: 77459903

GI number: 77459903

Start: 4165774

End: 4166673

Strand: Direct

Name: cmpR [H]

Synonym: Pfl01_3681

Alternate gene names: 77459903

Gene position: 4165774-4166673 (Clockwise)

Preceding gene: 77459900

Following gene: 77459905

Centisome position: 64.7

GC content: 62.89

Gene sequence:

>900_bases
ATGTCGGTTTCACACGCCCAGCTCAAAGCCTTTCACGCCGTGGCCGTGCACGGAAGCTTCACCAAGGCCGCCGAGCGGCT
TTATCTGACGCAACCGGCGATTTCCGACCAGGTGCGCAAGCTGGAAGAACGCTTCGGCGTGTTGCTGTTCCATCGCAACA
AACGCTCGGTGCGCCTGACCGATTTGGGCGAACGCTTGCTGGCAATCACCCAGCGTCTGTTCGTGGTCGAGGCCGAAGCC
CAGGAGTTGCTGCAGGAATCCCAGGCCTTGCAGACTGGCAGTCTGATACTGGCAGTGGATGCGCCGGTGCATGTGCTGCC
GCAGATCGCCCGGTTCTGCGAACGCTACCCGGGGATCAGCGTGAAAATCGAGACCGGCAATACCGATGAATCGCTGTTTC
GACTGTTCAACTATCAGGCCGATCTGGCGTTGCTCGGTCGCGATGTCAGCGATGAACGCCTGCTGTGTGTGCCGCTGCGC
AACGACCCGATGGTGGCGTTCGTCTCGCGCCATCATCCGTGGGCCGAGCGTGAATCGATCTGTCTGGAAGATCTGGACGA
CACGCCGCTGGTGCTGCGCGAACACGGCTCGGTGACTCGCCAGACCCTGGAAGAAGAAATGGCCCGCGCCGGCTTCCGCA
TCCGCCCGGCGATCCAGGTCGAAGGCCGGGAAGCCGCGCGGGAGGCCGTGGTGGTGGGGATTGGCGTGGGTGTGGTGTCG
GCGGCGGAGTTTGGTGCGGACTCACGGGTTTGCGCGTTGCCGATCACCGATTGCACCCGGAGGTTGACCGAAACGCTGGT
GTGCCTGCGCGAGCAAAGTTCGCGGCGGGTGGTGGCGACGTTTCTCGAGATGGTTCGCGAGAGTCTTGTTCAGACCGGGG
CCAACCCGAAAAACGCCTGA

Upstream 100 bases:

>100_bases
GATCAAAGCAATTACTGTTTAATAAATAAAATCGATTTATCGTATTTCACACATAAGCTCAGCTTGTTACTGAAGTTCGC
CTGTAAACGAGGAATCAGCC

Downstream 100 bases:

>100_bases
ATCAAGCGCAACTCCCGCCGCCGCTCCACGCAGCCGATCATGTGCCGGTTCACCAGCCCTTCTCCCGCAATGGGAATCGC
GACGACACGGGGGTCATGAC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 299; Mature: 298

Protein sequence:

>299_residues
MSVSHAQLKAFHAVAVHGSFTKAAERLYLTQPAISDQVRKLEERFGVLLFHRNKRSVRLTDLGERLLAITQRLFVVEAEA
QELLQESQALQTGSLILAVDAPVHVLPQIARFCERYPGISVKIETGNTDESLFRLFNYQADLALLGRDVSDERLLCVPLR
NDPMVAFVSRHHPWAERESICLEDLDDTPLVLREHGSVTRQTLEEEMARAGFRIRPAIQVEGREAAREAVVVGIGVGVVS
AAEFGADSRVCALPITDCTRRLTETLVCLREQSSRRVVATFLEMVRESLVQTGANPKNA

Sequences:

>Translated_299_residues
MSVSHAQLKAFHAVAVHGSFTKAAERLYLTQPAISDQVRKLEERFGVLLFHRNKRSVRLTDLGERLLAITQRLFVVEAEA
QELLQESQALQTGSLILAVDAPVHVLPQIARFCERYPGISVKIETGNTDESLFRLFNYQADLALLGRDVSDERLLCVPLR
NDPMVAFVSRHHPWAERESICLEDLDDTPLVLREHGSVTRQTLEEEMARAGFRIRPAIQVEGREAAREAVVVGIGVGVVS
AAEFGADSRVCALPITDCTRRLTETLVCLREQSSRRVVATFLEMVRESLVQTGANPKNA
>Mature_298_residues
SVSHAQLKAFHAVAVHGSFTKAAERLYLTQPAISDQVRKLEERFGVLLFHRNKRSVRLTDLGERLLAITQRLFVVEAEAQ
ELLQESQALQTGSLILAVDAPVHVLPQIARFCERYPGISVKIETGNTDESLFRLFNYQADLALLGRDVSDERLLCVPLRN
DPMVAFVSRHHPWAERESICLEDLDDTPLVLREHGSVTRQTLEEEMARAGFRIRPAIQVEGREAAREAVVVGIGVGVVSA
AEFGADSRVCALPITDCTRRLTETLVCLREQSSRRVVATFLEMVRESLVQTGANPKNA

Specific function: Activates transcription of the cmpABCD operon under carbon dioxide-limited conditions. Specifically binds to the cmpR- cmpA intergenic region [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI157672245, Length=300, Percent_Identity=29.3333333333333, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI145693105, Length=263, Percent_Identity=26.9961977186312, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1790399, Length=233, Percent_Identity=27.8969957081545, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1787530, Length=241, Percent_Identity=27.8008298755187, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1788481, Length=243, Percent_Identity=26.3374485596708, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1789173, Length=124, Percent_Identity=37.0967741935484, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787879, Length=247, Percent_Identity=28.7449392712551, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1786401, Length=164, Percent_Identity=31.0975609756098, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1788296, Length=280, Percent_Identity=24.6428571428571, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1788887, Length=190, Percent_Identity=30.5263157894737, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1790208, Length=239, Percent_Identity=25.1046025104602, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1788748, Length=245, Percent_Identity=26.9387755102041, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1788706, Length=153, Percent_Identity=33.3333333333333, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI1787806, Length=285, Percent_Identity=23.1578947368421, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1786713, Length=138, Percent_Identity=39.1304347826087, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1787589, Length=129, Percent_Identity=37.2093023255814, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1787601, Length=203, Percent_Identity=27.0935960591133, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33321; Mature: 33189

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVSHAQLKAFHAVAVHGSFTKAAERLYLTQPAISDQVRKLEERFGVLLFHRNKRSVRLT
CCCCHHHHHHHHHEEECCCHHHHHHHHEECCCHHHHHHHHHHHHCCEEEEECCCCEEEHH
DLGERLLAITQRLFVVEAEAQELLQESQALQTGSLILAVDAPVHVLPQIARFCERYPGIS
HHHHHHHHHHHHHHEEEHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHCCCCE
VKIETGNTDESLFRLFNYQADLALLGRDVSDERLLCVPLRNDPMVAFVSRHHPWAERESI
EEEECCCCHHHHHHHHCCCCCHHEECCCCCCCCEEEEEECCCCEEEEEECCCCCHHHHCH
CLEDLDDTPLVLREHGSVTRQTLEEEMARAGFRIRPAIQVEGREAAREAVVVGIGVGVVS
HHHCCCCCCEEEECCCHHHHHHHHHHHHHCCCEECCEEEECCHHHHHHEEEEEECHHHHH
AAEFGADSRVCALPITDCTRRLTETLVCLREQSSRRVVATFLEMVRESLVQTGANPKNA
HHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SVSHAQLKAFHAVAVHGSFTKAAERLYLTQPAISDQVRKLEERFGVLLFHRNKRSVRLT
CCCHHHHHHHHHEEECCCHHHHHHHHEECCCHHHHHHHHHHHHCCEEEEECCCCEEEHH
DLGERLLAITQRLFVVEAEAQELLQESQALQTGSLILAVDAPVHVLPQIARFCERYPGIS
HHHHHHHHHHHHHHEEEHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHCCCCE
VKIETGNTDESLFRLFNYQADLALLGRDVSDERLLCVPLRNDPMVAFVSRHHPWAERESI
EEEECCCCHHHHHHHHCCCCCHHEECCCCCCCCEEEEEECCCCEEEEEECCCCCHHHHCH
CLEDLDDTPLVLREHGSVTRQTLEEEMARAGFRIRPAIQVEGREAAREAVVVGIGVGVVS
HHHCCCCCCEEEECCCHHHHHHHHHHHHHCCCEECCEEEECCHHHHHHEEEEEECHHHHH
AAEFGADSRVCALPITDCTRRLTETLVCLREQSSRRVVATFLEMVRESLVQTGANPKNA
HHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]