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The map label for this gene is phnW

Identifier: 77459905

GI number: 77459905

Start: 4167617

End: 4168726

Strand: Direct

Name: phnW

Synonym: Pfl01_3683

Alternate gene names: 77459905

Gene position: 4167617-4168726 (Clockwise)

Preceding gene: 77459903

Following gene: 77459906

Centisome position: 64.73

GC content: 63.33

Gene sequence:

>1110_bases
ATGAGTACTGCCGCACCCATCCTGCTCACTCCCGGCCCGTTGACCACCTCGGCCCGCACCCGCCAGGCGATGATGGTCGA
CTGGGGTTCATGGGATGACCGCTTCAACCAATTGACCGCCAGCCTGTGCGAACAACTGCTGGCGATTCTCAACGGCGCCG
ACAGCCATCACTGCGTACCGTTGCAGGGCAGCGGCACCTTCGCCGTCGAAGCCGCGATCGGCACCCTCGTCCCCCGTGAC
GGCAAGGTCCTGGTGCTGATCAACGGCGCTTACGGCAAGCGTCTGGCGAAAATCTGCGAAGTGCTGGGCCGCTCGTTCAG
CACCTTCGAAACCGCTGAAGACGAACCGACCACCGCCGCCGACGTCGACCGCCTGCTGTGTGCCGACAGCGACATTACCC
ACGTCGCGCTGATCCACTGCGAAACCAGCACCGGCATCCTCAATCCGCTGCCGGAAATCGCTCAGGTTGTAGAGCAGCAC
GGCAAACGCTTGATCATTGATGCCATGAGCTCGTTCGGCGCGTTGCCGGTGGACGCGCAAAAAGTCCCGTTCGACGCGCT
GATTGCCGCCTCCGGCAAATGCCTGGAAGGCGTACCGGGCATGGGCTTCGTGTTCGCCCGCAAGGAATCTCTGGCCGCAG
CCGCCGGCAATTCGCATTCGCTGGCGATGGACCTGTTCGACCAGCACAGCTACATGAAAAAAACCGGCCAGTGGCGCTTC
ACCCCGCCGACCCACGTGGTCGCGGCGCTGCACGAAGCGCTGCTGCAATACAACGAAGAAGGCGGCCTGCCGGCACGGCA
TGCGCGTTACGCCGCCAACTGCCAGGCGTTGATGGAAGAGATGGGCAAACTCGGCTTGCGCAGCTTCCTGCCCGCCGCGA
TCCAGGCGCCGATCATCGCAACCTTCCACGCACCGAAAGATCCGCGCTACCAGTTCAAGGACTTCTACGAACGTGTCAAG
GCCAAGGGTTACATCCTCTACCCCGGCAAGCTGACCCAGGTCGAAACCTTCCGCGTCGGCTGCATCGGCCACGTCACCCC
GGCGCAGATGCGCGAAGCCGTCGCGGCGGTGAGTGAAGTGCTGCGCGAGATGGAAGTGCTCGACATCTGA

Upstream 100 bases:

>100_bases
TGATGGCTGGCATAACAACAAACAATTTGATTGATGATCCGGCGAATTGCAACGTAGGCCCCGTAGCTTCATCCCACAGC
GCTATCGCGAGGACATACGA

Downstream 100 bases:

>100_bases
TTCACCCGGCCCGCTCCCTTATTTGAATTGCCTTGCCCACACAGGATTCTGACCAACATGAACTACAACAACCCAACCCA
GCTGCAAGCCGCCATCCTCG

Product: 2-aminoethylphosphonate--pyruvate transaminase

Products: NA

Alternate protein names: 2-aminoethylphosphonate aminotransferase; AEP transaminase; AEPT

Number of amino acids: Translated: 369; Mature: 368

Protein sequence:

>369_residues
MSTAAPILLTPGPLTTSARTRQAMMVDWGSWDDRFNQLTASLCEQLLAILNGADSHHCVPLQGSGTFAVEAAIGTLVPRD
GKVLVLINGAYGKRLAKICEVLGRSFSTFETAEDEPTTAADVDRLLCADSDITHVALIHCETSTGILNPLPEIAQVVEQH
GKRLIIDAMSSFGALPVDAQKVPFDALIAASGKCLEGVPGMGFVFARKESLAAAAGNSHSLAMDLFDQHSYMKKTGQWRF
TPPTHVVAALHEALLQYNEEGGLPARHARYAANCQALMEEMGKLGLRSFLPAAIQAPIIATFHAPKDPRYQFKDFYERVK
AKGYILYPGKLTQVETFRVGCIGHVTPAQMREAVAAVSEVLREMEVLDI

Sequences:

>Translated_369_residues
MSTAAPILLTPGPLTTSARTRQAMMVDWGSWDDRFNQLTASLCEQLLAILNGADSHHCVPLQGSGTFAVEAAIGTLVPRD
GKVLVLINGAYGKRLAKICEVLGRSFSTFETAEDEPTTAADVDRLLCADSDITHVALIHCETSTGILNPLPEIAQVVEQH
GKRLIIDAMSSFGALPVDAQKVPFDALIAASGKCLEGVPGMGFVFARKESLAAAAGNSHSLAMDLFDQHSYMKKTGQWRF
TPPTHVVAALHEALLQYNEEGGLPARHARYAANCQALMEEMGKLGLRSFLPAAIQAPIIATFHAPKDPRYQFKDFYERVK
AKGYILYPGKLTQVETFRVGCIGHVTPAQMREAVAAVSEVLREMEVLDI
>Mature_368_residues
STAAPILLTPGPLTTSARTRQAMMVDWGSWDDRFNQLTASLCEQLLAILNGADSHHCVPLQGSGTFAVEAAIGTLVPRDG
KVLVLINGAYGKRLAKICEVLGRSFSTFETAEDEPTTAADVDRLLCADSDITHVALIHCETSTGILNPLPEIAQVVEQHG
KRLIIDAMSSFGALPVDAQKVPFDALIAASGKCLEGVPGMGFVFARKESLAAAAGNSHSLAMDLFDQHSYMKKTGQWRFT
PPTHVVAALHEALLQYNEEGGLPARHARYAANCQALMEEMGKLGLRSFLPAAIQAPIIATFHAPKDPRYQFKDFYERVKA
KGYILYPGKLTQVETFRVGCIGHVTPAQMREAVAAVSEVLREMEVLDI

Specific function: Involved in phosphonate degradation

COG id: COG0075

COG function: function code E; Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily

Homologues:

Organism=Homo sapiens, GI4557289, Length=372, Percent_Identity=24.7311827956989, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17536281, Length=347, Percent_Identity=23.6311239193084, Blast_Score=79, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PHNW_PSEPF (Q3K9Y3)

Other databases:

- EMBL:   CP000094
- RefSeq:   YP_349412.1
- ProteinModelPortal:   Q3K9Y3
- SMR:   Q3K9Y3
- STRING:   Q3K9Y3
- GeneID:   3715129
- GenomeReviews:   CP000094_GR
- KEGG:   pfo:Pfl01_3683
- eggNOG:   COG0075
- HOGENOM:   HBG423997
- OMA:   HSLAMDL
- ProtClustDB:   PRK13479
- BioCyc:   PFLU205922:PFL_3683-MONOMER
- HAMAP:   MF_01376
- InterPro:   IPR017688
- InterPro:   IPR000192
- InterPro:   IPR012703
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- Gene3D:   G3DSA:3.40.640.10
- Gene3D:   G3DSA:3.90.1150.10
- TIGRFAMs:   TIGR03301
- TIGRFAMs:   TIGR02326

Pfam domain/function: PF00266 Aminotran_5; SSF53383 PyrdxlP-dep_Trfase_major

EC number: =2.6.1.37

Molecular weight: Translated: 39959; Mature: 39828

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS00595 AA_TRANSFER_CLASS_5; PS00626 RCC1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTAAPILLTPGPLTTSARTRQAMMVDWGSWDDRFNQLTASLCEQLLAILNGADSHHCVP
CCCCCCEEECCCCCCCCCHHCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEE
LQGSGTFAVEAAIGTLVPRDGKVLVLINGAYGKRLAKICEVLGRSFSTFETAEDEPTTAA
ECCCCCEEEEEHHHHCCCCCCCEEEEEECHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHH
DVDRLLCADSDITHVALIHCETSTGILNPLPEIAQVVEQHGKRLIIDAMSSFGALPVDAQ
HHHHHHHCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHCCCEEEEEHHHHCCCCCCCCC
KVPFDALIAASGKCLEGVPGMGFVFARKESLAAAAGNSHSLAMDLFDQHSYMKKTGQWRF
CCCHHHHHHCCCCHHCCCCCCCEEEEEHHHHHHHCCCCCEEHHHHHHHHHHHHHCCCEEE
TPPTHVVAALHEALLQYNEEGGLPARHARYAANCQALMEEMGKLGLRSFLPAAIQAPIIA
CCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
TFHAPKDPRYQFKDFYERVKAKGYILYPGKLTQVETFRVGCIGHVTPAQMREAVAAVSEV
EECCCCCCCHHHHHHHHHHHHCEEEECCCCCCEEEEEEECEECCCCHHHHHHHHHHHHHH
LREMEVLDI
HHHHHHHCC
>Mature Secondary Structure 
STAAPILLTPGPLTTSARTRQAMMVDWGSWDDRFNQLTASLCEQLLAILNGADSHHCVP
CCCCCEEECCCCCCCCCHHCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEE
LQGSGTFAVEAAIGTLVPRDGKVLVLINGAYGKRLAKICEVLGRSFSTFETAEDEPTTAA
ECCCCCEEEEEHHHHCCCCCCCEEEEEECHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHH
DVDRLLCADSDITHVALIHCETSTGILNPLPEIAQVVEQHGKRLIIDAMSSFGALPVDAQ
HHHHHHHCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHCCCEEEEEHHHHCCCCCCCCC
KVPFDALIAASGKCLEGVPGMGFVFARKESLAAAAGNSHSLAMDLFDQHSYMKKTGQWRF
CCCHHHHHHCCCCHHCCCCCCCEEEEEHHHHHHHCCCCCEEHHHHHHHHHHHHHCCCEEE
TPPTHVVAALHEALLQYNEEGGLPARHARYAANCQALMEEMGKLGLRSFLPAAIQAPIIA
CCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
TFHAPKDPRYQFKDFYERVKAKGYILYPGKLTQVETFRVGCIGHVTPAQMREAVAAVSEV
EECCCCCCCHHHHHHHHHHHHCEEEECCCCCCEEEEEEECEECCCCHHHHHHHHHHHHHH
LREMEVLDI
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA