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The map label for this gene is 77459898

Identifier: 77459898

GI number: 77459898

Start: 4159007

End: 4160320

Strand: Direct

Name: 77459898

Synonym: Pfl01_3676

Alternate gene names: NA

Gene position: 4159007-4160320 (Clockwise)

Preceding gene: 77459897

Following gene: 77459900

Centisome position: 64.6

GC content: 63.62

Gene sequence:

>1314_bases
ATGCACACCCTTGCACAACTGCGCGCCGGCGAACTGTCGCGCATCACCCGGCTGGACCTGGCCGAAGGACTGACTGAATT
TCCGCCGGAGATTTTCAACCTGGCCGACACGCTGGAAGTGCTCAACCTCAGCGGTAACGCCCTGAGCAGCCTGCCGGACG
ACTTGCACCGTCTGACGCGCCTGCGCGTGCTGTTCTGCTCCGACAATCAGTTCACGCAATTGCCGGCGTGCCTGGGCCAG
TGCCAGGCGCTGACGATGATCGGCTTCAAGGCCAACCGCATCACTCAGGTGCCCGGCGCGGCGCTGCCGCCAAATCTGCG
CTGGCTGATCCTGACCGACAACGCCATCGAAACCCTCCCCACCGAACTGGGCGAACGTCCGCTGCTGCAAAAACTCATGC
TTGCCGGCAATCGTCTGAACACCCTGCCGCCGTCACTGAGCCAGTGCCATCGACTGGAGCTGATCCGCATCGCCGCCAAC
CAGTTGACCGAGTTGCCGCAATGGCTGCTGACCCTGCCGAGCCTGACCTGGCTGGCCTACGCCGGCAATCCGCTGGAAAC
CGAAGCCGATGCGGCCGCCCTCGACAAAGCGCCACTGATCGACTGGTCGGCGCTGCAATTGGAACAACCGCTGGGCGAAG
GCGCTTCCGGGGTCATTTACCGGGCGCAGTGGCAGCCCGCGAATCAGCCGGCCACGTCCGTGGCAGTCAAGTTGTACAAG
GGCGAAATGACCAGCGACGGCTCGCCGCTGCATGAAATGAACGCGTGCATCACCGCCGGGCTGCACCCGAACCTGATCCG
CGTCGAAGGCCGCATCGACCAGCATCCCGATGGCCAGCAAGGTCTGGTGATGCAGTTGATCGATCCGAGCTATCGCAACC
TGGCCGGGCTGCCGAGCCTGGCGTCCTGTTCACGGGACGTATATGCCGACGATTGTCGTTTCAGTGCCGACGTTGCCCTG
CGTATCGCTCGCGGCATAGCCTCTGTCGCCGGGCATCTGCACCGTCGCGGCATCACCCATGGCGATCTCTACGGACACAA
CATTCTGTTGAACGATCAGGGCGACTGTCTGCTGGGGGACTTTGGCGCGGCGTCGTTCCATGCCATGGCGGACACGCCTG
AAACCCGCGCGCTGCAACGCCTCGAAGTGCGTGCGTTCGGGATTTTACTGGGGGAACTGCTGACGCGTATCGACTCGGGG
TTGAGCGATGAACAGCGTCAGGTGCTAGAGGCCCTGGAACAGCGCTGCTGTCAGCCGGATGTGCTGGCGCGGCCGGGGTT
TGGCGAGATCAGCCAGGCGTTGCAACACGCCTGA

Upstream 100 bases:

>100_bases
GGCTCGGGCAATTGCGCGAAGTGCACGAACCAGGCTGATTTGCCGTTATCATGCGGTCCATTTCCGGCGCCCTGCGCCTT
CTCGATAGCGATCCTTTTTC

Downstream 100 bases:

>100_bases
AAAAAAATCGCAGCCCGAGGGCTGCGATTTTCCGGTTTGTCAGCCGGCCAGACCGACGAACATATCCTGCACGTCGTCAT
GGTTGTCCAGGCCTTCGAGG

Product: Serine/threonine protein kinase

Products: NA

Alternate protein names: Leucine-Rich Repeat-Containing Protein; Protein Kinase; Cytoplasmic Membrane Protein; Leucine-Rich Repeat Protein; Leucine-Rich Repeat-Containing Protein Kinase; Ras Family; Miro-Like Protein; Outer Membrane Protein; Kinase; Phosphoprotein Phosphatase; Serine/Threonine-Protein Kinase-Like Domain Protein; Miro Domain Protein; Miro Domain-Containing Protein; Serine/Threonine-Protein Kinase-Like Domain; Molybdate Metabolism Regulator; Protein Kinase Domain-Containing Protein; Leucine Rich Repeat Domain Protein; Leucine-Rich Repeat-Containing Protein Typical Subtype; Outermembrane Protein; Protein KinaseLeucine-Rich Repeat Protein; Lipoprotein

Number of amino acids: Translated: 437; Mature: 437

Protein sequence:

>437_residues
MHTLAQLRAGELSRITRLDLAEGLTEFPPEIFNLADTLEVLNLSGNALSSLPDDLHRLTRLRVLFCSDNQFTQLPACLGQ
CQALTMIGFKANRITQVPGAALPPNLRWLILTDNAIETLPTELGERPLLQKLMLAGNRLNTLPPSLSQCHRLELIRIAAN
QLTELPQWLLTLPSLTWLAYAGNPLETEADAAALDKAPLIDWSALQLEQPLGEGASGVIYRAQWQPANQPATSVAVKLYK
GEMTSDGSPLHEMNACITAGLHPNLIRVEGRIDQHPDGQQGLVMQLIDPSYRNLAGLPSLASCSRDVYADDCRFSADVAL
RIARGIASVAGHLHRRGITHGDLYGHNILLNDQGDCLLGDFGAASFHAMADTPETRALQRLEVRAFGILLGELLTRIDSG
LSDEQRQVLEALEQRCCQPDVLARPGFGEISQALQHA

Sequences:

>Translated_437_residues
MHTLAQLRAGELSRITRLDLAEGLTEFPPEIFNLADTLEVLNLSGNALSSLPDDLHRLTRLRVLFCSDNQFTQLPACLGQ
CQALTMIGFKANRITQVPGAALPPNLRWLILTDNAIETLPTELGERPLLQKLMLAGNRLNTLPPSLSQCHRLELIRIAAN
QLTELPQWLLTLPSLTWLAYAGNPLETEADAAALDKAPLIDWSALQLEQPLGEGASGVIYRAQWQPANQPATSVAVKLYK
GEMTSDGSPLHEMNACITAGLHPNLIRVEGRIDQHPDGQQGLVMQLIDPSYRNLAGLPSLASCSRDVYADDCRFSADVAL
RIARGIASVAGHLHRRGITHGDLYGHNILLNDQGDCLLGDFGAASFHAMADTPETRALQRLEVRAFGILLGELLTRIDSG
LSDEQRQVLEALEQRCCQPDVLARPGFGEISQALQHA
>Mature_437_residues
MHTLAQLRAGELSRITRLDLAEGLTEFPPEIFNLADTLEVLNLSGNALSSLPDDLHRLTRLRVLFCSDNQFTQLPACLGQ
CQALTMIGFKANRITQVPGAALPPNLRWLILTDNAIETLPTELGERPLLQKLMLAGNRLNTLPPSLSQCHRLELIRIAAN
QLTELPQWLLTLPSLTWLAYAGNPLETEADAAALDKAPLIDWSALQLEQPLGEGASGVIYRAQWQPANQPATSVAVKLYK
GEMTSDGSPLHEMNACITAGLHPNLIRVEGRIDQHPDGQQGLVMQLIDPSYRNLAGLPSLASCSRDVYADDCRFSADVAL
RIARGIASVAGHLHRRGITHGDLYGHNILLNDQGDCLLGDFGAASFHAMADTPETRALQRLEVRAFGILLGELLTRIDSG
LSDEQRQVLEALEQRCCQPDVLARPGFGEISQALQHA

Specific function: Unknown

COG id: COG4886

COG function: function code S; Leucine-rich repeat (LRR) protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI8923909, Length=177, Percent_Identity=32.2033898305085, Blast_Score=83, Evalue=6e-16,
Organism=Homo sapiens, GI55770895, Length=179, Percent_Identity=32.4022346368715, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI187829877, Length=228, Percent_Identity=28.9473684210526, Blast_Score=79, Evalue=9e-15,
Organism=Homo sapiens, GI62241040, Length=228, Percent_Identity=28.9473684210526, Blast_Score=79, Evalue=9e-15,
Organism=Homo sapiens, GI187829871, Length=228, Percent_Identity=28.9473684210526, Blast_Score=79, Evalue=9e-15,
Organism=Homo sapiens, GI238908508, Length=163, Percent_Identity=33.1288343558282, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI95113664, Length=163, Percent_Identity=34.3558282208589, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI41281398, Length=177, Percent_Identity=33.8983050847458, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI16904383, Length=178, Percent_Identity=31.4606741573034, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI153792305, Length=166, Percent_Identity=34.3373493975904, Blast_Score=76, Evalue=6e-14,
Organism=Homo sapiens, GI194394161, Length=186, Percent_Identity=30.6451612903226, Blast_Score=76, Evalue=7e-14,
Organism=Homo sapiens, GI122937315, Length=186, Percent_Identity=31.1827956989247, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI6912638, Length=162, Percent_Identity=35.8024691358025, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI45827729, Length=154, Percent_Identity=32.4675324675325, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI45827731, Length=154, Percent_Identity=32.4675324675325, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI190014581, Length=195, Percent_Identity=30.2564102564103, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI19923729, Length=203, Percent_Identity=29.064039408867, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI157694513, Length=327, Percent_Identity=27.82874617737, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI110825984, Length=179, Percent_Identity=35.195530726257, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI21389431, Length=154, Percent_Identity=31.8181818181818, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI197333706, Length=166, Percent_Identity=29.5180722891566, Blast_Score=70, Evalue=6e-12,
Organism=Homo sapiens, GI34222199, Length=166, Percent_Identity=29.5180722891566, Blast_Score=70, Evalue=6e-12,
Organism=Homo sapiens, GI21361633, Length=178, Percent_Identity=31.4606741573034, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI167466264, Length=151, Percent_Identity=33.112582781457, Blast_Score=69, Evalue=8e-12,
Organism=Homo sapiens, GI65301141, Length=156, Percent_Identity=32.6923076923077, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI34577083, Length=145, Percent_Identity=34.4827586206897, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI223005922, Length=144, Percent_Identity=34.7222222222222, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI157743290, Length=165, Percent_Identity=31.5151515151515, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI63003903, Length=252, Percent_Identity=26.1904761904762, Blast_Score=67, Evalue=5e-11,
Organism=Homo sapiens, GI61742786, Length=152, Percent_Identity=38.1578947368421, Blast_Score=65, Evalue=1e-10,
Organism=Caenorhabditis elegans, GI71991531, Length=212, Percent_Identity=29.2452830188679, Blast_Score=79, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI71991525, Length=212, Percent_Identity=29.2452830188679, Blast_Score=78, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI71998904, Length=180, Percent_Identity=34.4444444444444, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71998900, Length=180, Percent_Identity=34.4444444444444, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17550406, Length=210, Percent_Identity=29.0476190476191, Blast_Score=72, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI71985928, Length=192, Percent_Identity=30.7291666666667, Blast_Score=72, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI71981160, Length=205, Percent_Identity=29.7560975609756, Blast_Score=71, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17552452, Length=211, Percent_Identity=32.7014218009479, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71981152, Length=205, Percent_Identity=29.7560975609756, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17537883, Length=177, Percent_Identity=29.9435028248588, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71993778, Length=215, Percent_Identity=29.3023255813954, Blast_Score=69, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI71993783, Length=215, Percent_Identity=29.3023255813954, Blast_Score=68, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6322455, Length=206, Percent_Identity=30.5825242718447, Blast_Score=66, Evalue=1e-11,
Organism=Drosophila melanogaster, GI281362653, Length=173, Percent_Identity=34.6820809248555, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI281362657, Length=173, Percent_Identity=34.6820809248555, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI281362651, Length=173, Percent_Identity=34.6820809248555, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24650330, Length=173, Percent_Identity=34.6820809248555, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24650334, Length=173, Percent_Identity=34.6820809248555, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24650332, Length=173, Percent_Identity=34.6820809248555, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI281362655, Length=173, Percent_Identity=34.6820809248555, Blast_Score=86, Evalue=6e-17,
Organism=Drosophila melanogaster, GI116007092, Length=173, Percent_Identity=34.6820809248555, Blast_Score=86, Evalue=6e-17,
Organism=Drosophila melanogaster, GI62472958, Length=173, Percent_Identity=34.6820809248555, Blast_Score=86, Evalue=7e-17,
Organism=Drosophila melanogaster, GI24650336, Length=173, Percent_Identity=34.6820809248555, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI221379725, Length=176, Percent_Identity=33.5227272727273, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI221379722, Length=176, Percent_Identity=33.5227272727273, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24667524, Length=195, Percent_Identity=37.9487179487179, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI17933612, Length=164, Percent_Identity=32.9268292682927, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI19922706, Length=185, Percent_Identity=31.8918918918919, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI161078262, Length=163, Percent_Identity=33.1288343558282, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI161078260, Length=159, Percent_Identity=33.9622641509434, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI45551891, Length=159, Percent_Identity=33.9622641509434, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI161078264, Length=163, Percent_Identity=33.1288343558282, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21358045, Length=147, Percent_Identity=34.0136054421769, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24641036, Length=130, Percent_Identity=34.6153846153846, Blast_Score=66, Evalue=4e-11,
Organism=Drosophila melanogaster, GI19922294, Length=159, Percent_Identity=28.3018867924528, Blast_Score=66, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 47699; Mature: 47699

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: PS00107 PROTEIN_KINASE_ATP ; PS50011 PROTEIN_KINASE_DOM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHTLAQLRAGELSRITRLDLAEGLTEFPPEIFNLADTLEVLNLSGNALSSLPDDLHRLTR
CCCHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHCHHHHHHHHH
LRVLFCSDNQFTQLPACLGQCQALTMIGFKANRITQVPGAALPPNLRWLILTDNAIETLP
EEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCEEEEEECCHHHHHH
TELGERPLLQKLMLAGNRLNTLPPSLSQCHRLELIRIAANQLTELPQWLLTLPSLTWLAY
HHHCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEE
AGNPLETEADAAALDKAPLIDWSALQLEQPLGEGASGVIYRAQWQPANQPATSVAVKLYK
CCCCCCCCCHHHHHCCCCCCCHHHHHHHHCCCCCCCCEEEEEECCCCCCCHHHHEEEEEE
GEMTSDGSPLHEMNACITAGLHPNLIRVEGRIDQHPDGQQGLVMQLIDPSYRNLAGLPSL
CCCCCCCCCHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCEEEEECCCCHHHHCCCCCH
ASCSRDVYADDCRFSADVALRIARGIASVAGHLHRRGITHGDLYGHNILLNDQGDCLLGD
HHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCEEEEC
FGAASFHAMADTPETRALQRLEVRAFGILLGELLTRIDSGLSDEQRQVLEALEQRCCQPD
CCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCC
VLARPGFGEISQALQHA
CCCCCCHHHHHHHHHCC
>Mature Secondary Structure
MHTLAQLRAGELSRITRLDLAEGLTEFPPEIFNLADTLEVLNLSGNALSSLPDDLHRLTR
CCCHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHCHHHHHHHHH
LRVLFCSDNQFTQLPACLGQCQALTMIGFKANRITQVPGAALPPNLRWLILTDNAIETLP
EEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCEEEEEECCHHHHHH
TELGERPLLQKLMLAGNRLNTLPPSLSQCHRLELIRIAANQLTELPQWLLTLPSLTWLAY
HHHCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEE
AGNPLETEADAAALDKAPLIDWSALQLEQPLGEGASGVIYRAQWQPANQPATSVAVKLYK
CCCCCCCCCHHHHHCCCCCCCHHHHHHHHCCCCCCCCEEEEEECCCCCCCHHHHEEEEEE
GEMTSDGSPLHEMNACITAGLHPNLIRVEGRIDQHPDGQQGLVMQLIDPSYRNLAGLPSL
CCCCCCCCCHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCEEEEECCCCHHHHCCCCCH
ASCSRDVYADDCRFSADVALRIARGIASVAGHLHRRGITHGDLYGHNILLNDQGDCLLGD
HHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCEEEEC
FGAASFHAMADTPETRALQRLEVRAFGILLGELLTRIDSGLSDEQRQVLEALEQRCCQPD
CCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCC
VLARPGFGEISQALQHA
CCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA