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The map label for this gene is acoR [H]

Identifier: 77459858

GI number: 77459858

Start: 4110063

End: 4111913

Strand: Direct

Name: acoR [H]

Synonym: Pfl01_3636

Alternate gene names: 77459858

Gene position: 4110063-4111913 (Clockwise)

Preceding gene: 77459851

Following gene: 77459862

Centisome position: 63.84

GC content: 61.05

Gene sequence:

>1851_bases
ATGGCCGCACCTGCCCCGCCGCTTTCCCACGATGCGATCGTCCAGGACTCCTGGTCCCGTTGCCGCGCCTTCGGTCTCAA
TCATCAAAGCGCCCCGGCCTTCGATCAGTTGCCCGCCGCCGGCATTGCGCAGTTGCTCGACCGCCATCATTCGCTGGTGC
AGACCACTCACCAGGAAGTGCTGCCGTATTACGAGAACATCCTGAGCAATTCCAATTGCCTGATCATGCTGGCCGACAAT
CAGGGCCAGGTGCTGACGTCCTGGGGCACCCAGCGCTTTATCGAGCCGAATCTGGCGCGCGGTTTTCAGGCCGGCGCCAG
TTGGGTCGAACGCGCCAGCGGCACCAACGCCATCGGCACGGCGCTGGCCTGCGAGCAGGCGGTGCACATCGAACACGATG
AACACTTTCTCAAGGCCAACCGCTTCATGACCGGTTCCGCCGCGCCGATTTTCGATGCCGAGCGCAAGGTCATCGCCGTA
CTTGATGTGTCCAGCGACAGCTATCTGCCGCCCTCGCACACCCTCGGCATGGTCAAGATGATGAGTCAGACCGTGGAAAA
CCGGCTGATCCTCAACCTGTTCCATGGCCAGTACTTTCAACTGACCTTCAACACCGGGTTGAACAACCTCGACAGCCAGT
GGGCCGGGCTGCTGATCTTTGATGAGAGCGGTCAGGTGTTGTCGGCCAACCGACGAGCCGACAATTTGCTGGGTGTGCGC
TTGTCGCGGGTCAGCGTTGAGAGCCTGTTCAAGGTGTCGTTGCTGGAGTTGATCAATCAGCCGGATGGGTTGCCGTTTGC
CTTGCAGACTTCCGGGCGCAATCGTTTCCAGTGTTTGTTGAAACGACCTAAACAAGCGCAGATTCAGGCGCGGGTCTTCA
CTGAAGCCAGACCCACCGAACCGAAAGTCGCCGTACCCACGGCCATCAGCCTGAGCACGTTGCACTTCGGTGACAGCCGC
GTGGAAAAAGCCGTGCGCCAGGCCGAACGCTTGCTGGAAAAGGACATCCCGCTGCTGATTCACGGGGAAACCGGGGTCGG
CAAGGAAGTCTTCGTCAAGGCCCTGCACCAGGCCAGCTCCCGCAGCAAACAGGCGTTCATTGCCGTCAACTGCGCGGCGA
TCCCCGCCGAACTGGTGGAGTCCGAGCTGTTCGGTTACGAGAAAGGCGCGTTCACCGGCGCCAACCAAAAAGGCAGCATT
GGCCTGATCCGTAAGGCCGACAAAGGCACGCTGTTCCTCGATGAAATCGGCGACATGCCGCTGCCGACTCAGGCTCGCTT
GTTGCGCGTATTGCAGGAGCGCTGCGTGCAACCGGTGGGCAGCAGCGAGCTGTTCCCGGTGGATCTGCGGATCATCTCCG
CCACCAATCGTTCGCTCCGGGAACAGGTGCAACTGGGGCGCTTTCGCGAGGATTTGTACTACCGCATCGGCGGTTTGACC
CTCGAATTGCCACCGCTTCGCGAGCGCAGCGACAAGCAGGCGCTGTTCAAACGGCTGTGGGAACAACATCGCGAGCCGTC
GCAGTGGGCGGGATTGAGTCGTGAGGTGCTGGAGCTGTTCGAGCGGCACCCGTGGCCGGGCAATCTGCGTCAGGTCAGCA
GCGTGATGCAGGTGGCACTGGCGATGGCCGAGGAACAACCGATTCGACCCGAGCATTTGCCGGACGACTTTTTTGTCGAT
CTGGAGATGGAGCCCGTGGAATTGGCCGAGCCGTTGGGCATCGACCTGAACGATGCCGAGGCGTTGAATCGGGAGTTGCA
GCTGGCCGGGGGCAATATTTCCCACCTGGCGCGGCGGTTGGGGGTGAGCCGCAATACGCTGTACAAGCGATTGCGGCAGA
TTGAAAGCTGA

Upstream 100 bases:

>100_bases
TGGATGCTTTTTGGCATGGATCCTGTGAGAGCGAGCTTGCTCACTCCCACAGAGATCTCAATAACAATAATAAAAATGCT
GTATTCAGAGGCTGACTGCC

Downstream 100 bases:

>100_bases
GCGCCTCCATAGCGGATCAGACCGAAACGGCTGGCTCAACAGGCGCCGCCGATGCCGCCGCCAACGTCCGCAGGCCCATC
GACACCACAACCATCATCAT

Product: sigma54 specific transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 616; Mature: 615

Protein sequence:

>616_residues
MAAPAPPLSHDAIVQDSWSRCRAFGLNHQSAPAFDQLPAAGIAQLLDRHHSLVQTTHQEVLPYYENILSNSNCLIMLADN
QGQVLTSWGTQRFIEPNLARGFQAGASWVERASGTNAIGTALACEQAVHIEHDEHFLKANRFMTGSAAPIFDAERKVIAV
LDVSSDSYLPPSHTLGMVKMMSQTVENRLILNLFHGQYFQLTFNTGLNNLDSQWAGLLIFDESGQVLSANRRADNLLGVR
LSRVSVESLFKVSLLELINQPDGLPFALQTSGRNRFQCLLKRPKQAQIQARVFTEARPTEPKVAVPTAISLSTLHFGDSR
VEKAVRQAERLLEKDIPLLIHGETGVGKEVFVKALHQASSRSKQAFIAVNCAAIPAELVESELFGYEKGAFTGANQKGSI
GLIRKADKGTLFLDEIGDMPLPTQARLLRVLQERCVQPVGSSELFPVDLRIISATNRSLREQVQLGRFREDLYYRIGGLT
LELPPLRERSDKQALFKRLWEQHREPSQWAGLSREVLELFERHPWPGNLRQVSSVMQVALAMAEEQPIRPEHLPDDFFVD
LEMEPVELAEPLGIDLNDAEALNRELQLAGGNISHLARRLGVSRNTLYKRLRQIES

Sequences:

>Translated_616_residues
MAAPAPPLSHDAIVQDSWSRCRAFGLNHQSAPAFDQLPAAGIAQLLDRHHSLVQTTHQEVLPYYENILSNSNCLIMLADN
QGQVLTSWGTQRFIEPNLARGFQAGASWVERASGTNAIGTALACEQAVHIEHDEHFLKANRFMTGSAAPIFDAERKVIAV
LDVSSDSYLPPSHTLGMVKMMSQTVENRLILNLFHGQYFQLTFNTGLNNLDSQWAGLLIFDESGQVLSANRRADNLLGVR
LSRVSVESLFKVSLLELINQPDGLPFALQTSGRNRFQCLLKRPKQAQIQARVFTEARPTEPKVAVPTAISLSTLHFGDSR
VEKAVRQAERLLEKDIPLLIHGETGVGKEVFVKALHQASSRSKQAFIAVNCAAIPAELVESELFGYEKGAFTGANQKGSI
GLIRKADKGTLFLDEIGDMPLPTQARLLRVLQERCVQPVGSSELFPVDLRIISATNRSLREQVQLGRFREDLYYRIGGLT
LELPPLRERSDKQALFKRLWEQHREPSQWAGLSREVLELFERHPWPGNLRQVSSVMQVALAMAEEQPIRPEHLPDDFFVD
LEMEPVELAEPLGIDLNDAEALNRELQLAGGNISHLARRLGVSRNTLYKRLRQIES
>Mature_615_residues
AAPAPPLSHDAIVQDSWSRCRAFGLNHQSAPAFDQLPAAGIAQLLDRHHSLVQTTHQEVLPYYENILSNSNCLIMLADNQ
GQVLTSWGTQRFIEPNLARGFQAGASWVERASGTNAIGTALACEQAVHIEHDEHFLKANRFMTGSAAPIFDAERKVIAVL
DVSSDSYLPPSHTLGMVKMMSQTVENRLILNLFHGQYFQLTFNTGLNNLDSQWAGLLIFDESGQVLSANRRADNLLGVRL
SRVSVESLFKVSLLELINQPDGLPFALQTSGRNRFQCLLKRPKQAQIQARVFTEARPTEPKVAVPTAISLSTLHFGDSRV
EKAVRQAERLLEKDIPLLIHGETGVGKEVFVKALHQASSRSKQAFIAVNCAAIPAELVESELFGYEKGAFTGANQKGSIG
LIRKADKGTLFLDEIGDMPLPTQARLLRVLQERCVQPVGSSELFPVDLRIISATNRSLREQVQLGRFREDLYYRIGGLTL
ELPPLRERSDKQALFKRLWEQHREPSQWAGLSREVLELFERHPWPGNLRQVSSVMQVALAMAEEQPIRPEHLPDDFFVDL
EMEPVELAEPLGIDLNDAEALNRELQLAGGNISHLARRLGVSRNTLYKRLRQIES

Specific function: Required for sigma-54-dependent transcription of acoXABC [H]

COG id: COG3284

COG function: function code QK; Transcriptional activator of acetoin/glycerol metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1789233, Length=478, Percent_Identity=33.4728033472803, Blast_Score=226, Evalue=3e-60,
Organism=Escherichia coli, GI1788905, Length=301, Percent_Identity=40.531561461794, Blast_Score=215, Evalue=8e-57,
Organism=Escherichia coli, GI1790437, Length=282, Percent_Identity=39.7163120567376, Blast_Score=206, Evalue=5e-54,
Organism=Escherichia coli, GI1788550, Length=292, Percent_Identity=41.4383561643836, Blast_Score=193, Evalue=3e-50,
Organism=Escherichia coli, GI1789087, Length=297, Percent_Identity=37.3737373737374, Blast_Score=191, Evalue=2e-49,
Organism=Escherichia coli, GI1790299, Length=312, Percent_Identity=41.3461538461538, Blast_Score=191, Evalue=2e-49,
Organism=Escherichia coli, GI87082117, Length=326, Percent_Identity=38.3435582822086, Blast_Score=190, Evalue=3e-49,
Organism=Escherichia coli, GI1786524, Length=296, Percent_Identity=40.2027027027027, Blast_Score=183, Evalue=3e-47,
Organism=Escherichia coli, GI87082152, Length=223, Percent_Identity=45.2914798206278, Blast_Score=182, Evalue=4e-47,
Organism=Escherichia coli, GI1787583, Length=304, Percent_Identity=35.5263157894737, Blast_Score=168, Evalue=1e-42,
Organism=Escherichia coli, GI87081872, Length=219, Percent_Identity=40.1826484018265, Blast_Score=149, Evalue=5e-37,
Organism=Escherichia coli, GI87081858, Length=638, Percent_Identity=23.1974921630094, Blast_Score=146, Evalue=4e-36,
Organism=Escherichia coli, GI1789828, Length=296, Percent_Identity=31.7567567567568, Blast_Score=129, Evalue=8e-31,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 68721; Mature: 68590

Theoretical pI: Translated: 6.76; Mature: 6.76

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAPAPPLSHDAIVQDSWSRCRAFGLNHQSAPAFDQLPAAGIAQLLDRHHSLVQTTHQEV
CCCCCCCCCCCHHHHCCHHHHHHHCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHH
LPYYENILSNSNCLIMLADNQGQVLTSWGTQRFIEPNLARGFQAGASWVERASGTNAIGT
HHHHHHHHCCCCEEEEEECCCCCEEECCCCCHHCCCHHHHHHHHHHHHHHHCCCCCHHHH
ALACEQAVHIEHDEHFLKANRFMTGSAAPIFDAERKVIAVLDVSSDSYLPPSHTLGMVKM
HHHHHHHHCCCCCHHHHHHCCEECCCCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHH
MSQTVENRLILNLFHGQYFQLTFNTGLNNLDSQWAGLLIFDESGQVLSANRRADNLLGVR
HHHHHHHHEEEEEECCCEEEEEECCCCCCCCCCCCEEEEECCCCCEEECCCCCCHHHHHH
LSRVSVESLFKVSLLELINQPDGLPFALQTSGRNRFQCLLKRPKQAQIQARVFTEARPTE
HHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHCCCCHHHHHHHEECCCCCCC
PKVAVPTAISLSTLHFGDSRVEKAVRQAERLLEKDIPLLIHGETGVGKEVFVKALHQASS
CCEECCCEEEEEEEECCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHC
RSKQAFIAVNCAAIPAELVESELFGYEKGAFTGANQKGSIGLIRKADKGTLFLDEIGDMP
CCCEEEEEEEEHHCCHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCEEHHHCCCCC
LPTQARLLRVLQERCVQPVGSSELFPVDLRIISATNRSLREQVQLGRFREDLYYRIGGLT
CCHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCEE
LELPPLRERSDKQALFKRLWEQHREPSQWAGLSREVLELFERHPWPGNLRQVSSVMQVAL
EECCCCCCCCCHHHHHHHHHHHCCCCHHHCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHH
AMAEEQPIRPEHLPDDFFVDLEMEPVELAEPLGIDLNDAEALNRELQLAGGNISHLARRL
HHHHCCCCCCCCCCCCEEEEEECCHHHHHCCCCCCCCCHHHHCCCCEECCCCHHHHHHHH
GVSRNTLYKRLRQIES
CCCHHHHHHHHHHHCC
>Mature Secondary Structure 
AAPAPPLSHDAIVQDSWSRCRAFGLNHQSAPAFDQLPAAGIAQLLDRHHSLVQTTHQEV
CCCCCCCCCCHHHHCCHHHHHHHCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHH
LPYYENILSNSNCLIMLADNQGQVLTSWGTQRFIEPNLARGFQAGASWVERASGTNAIGT
HHHHHHHHCCCCEEEEEECCCCCEEECCCCCHHCCCHHHHHHHHHHHHHHHCCCCCHHHH
ALACEQAVHIEHDEHFLKANRFMTGSAAPIFDAERKVIAVLDVSSDSYLPPSHTLGMVKM
HHHHHHHHCCCCCHHHHHHCCEECCCCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHH
MSQTVENRLILNLFHGQYFQLTFNTGLNNLDSQWAGLLIFDESGQVLSANRRADNLLGVR
HHHHHHHHEEEEEECCCEEEEEECCCCCCCCCCCCEEEEECCCCCEEECCCCCCHHHHHH
LSRVSVESLFKVSLLELINQPDGLPFALQTSGRNRFQCLLKRPKQAQIQARVFTEARPTE
HHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHCCCCHHHHHHHEECCCCCCC
PKVAVPTAISLSTLHFGDSRVEKAVRQAERLLEKDIPLLIHGETGVGKEVFVKALHQASS
CCEECCCEEEEEEEECCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHC
RSKQAFIAVNCAAIPAELVESELFGYEKGAFTGANQKGSIGLIRKADKGTLFLDEIGDMP
CCCEEEEEEEEHHCCHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCEEHHHCCCCC
LPTQARLLRVLQERCVQPVGSSELFPVDLRIISATNRSLREQVQLGRFREDLYYRIGGLT
CCHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCEE
LELPPLRERSDKQALFKRLWEQHREPSQWAGLSREVLELFERHPWPGNLRQVSSVMQVAL
EECCCCCCCCCHHHHHHHHHHHCCCCHHHCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHH
AMAEEQPIRPEHLPDDFFVDLEMEPVELAEPLGIDLNDAEALNRELQLAGGNISHLARRL
HHHHCCCCCCCCCCCCEEEEEECCHHHHHCCCCCCCCCHHHHCCCCEECCCCHHHHHHHH
GVSRNTLYKRLRQIES
CCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1378052 [H]