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The map label for this gene is pip [H]

Identifier: 77459851

GI number: 77459851

Start: 4102886

End: 4103764

Strand: Direct

Name: pip [H]

Synonym: Pfl01_3629

Alternate gene names: 77459851

Gene position: 4102886-4103764 (Clockwise)

Preceding gene: 77459850

Following gene: 77459858

Centisome position: 63.73

GC content: 59.84

Gene sequence:

>879_bases
ATGAGTTTTTCCCTGCACAGCCGAGGTTATTACCCGACCGGCGACGGCCATCAACTCTATTGGGAACGGCATGGTGTTCC
GGGACACGAACCGGTGTTTTTCCTCCATGGCGGCCCCGGCGGACGTTTCAGCCGCCACCATTTGCAGTTCTTCGACCAGG
GCCGGTTCGACATCATCCTGTTCGACCAACGGGGTTGCGGGCGCTCGACGCCTTACGGCGAGCTGCGGGACAACACTACC
GGGCTGTGTGTCGAAGACATCGATGCCCTGCGCCAGCATTTCGGCTTCGAAAAAATCAGCGTGCTGGGCGTGTCATGGGG
CAGTTGGCTGGCGATCCAGTACCAGCAGCGATATCCGCAGCACCTGCTGAAAAGCACACTGGTTTCGTTATTCGTGCCGT
TTGCCGCCAATGTCCGGGCCTACGATCAGGCGCTCAATGACGGGTTGGCGCAATCGCCTCAAATGTCGCCCGGCCAACGG
GCCAGCCACATCTACCGGATCCTCGGCGAAGGCTGTCCATCGCAGCAGCACCGCGCCGCCATCGAATGGTTGAACGCTGT
TCTACGTCGCTCAGGGCAGACGATTTGCCCCGACACCCTGGAGCGTTTCGTCGATCAGGAAGCCGTGCTTGCGATCCGTC
TGGAACTGCATTACCACCTGCAGAACTATTGCTTCACCCCAAAGGATGAAAACCTGACCCTCGACGACAACACCCTGCTG
ATCCAGGGCATCCGCGACACCCATGGCATGGCCAGCGTGCGCTGGCTCAGGCAACGCATGAACATCCACTGCCGGCTGCT
GCATGCCGGGCACAACGCCTTTGAAAATGCGATCCTCAAAGCGGTGCGTCGGGCGGTGAAACGTGAAATCGAGGGCTAA

Upstream 100 bases:

>100_bases
GGCTTGCCTCCATCCACCACCTGAAACTTGAATCCAGTGTCGCGGCACGGTCGGGGCAGGTCGAGCTGTTCCAGTTCTAT
CGTCTGACGGTTTCGGCGCC

Downstream 100 bases:

>100_bases
GAAAAACGGCACCCGAAGGTGCCGTCCCATTCCTCAAAAACCCTTACTTGCGTGCCGCCTCCCACGACTTGAGCAGTTCG
TTGTAGCTCACGGTTTCGCC

Product: alpha/beta hydrolase fold protein

Products: NA

Alternate protein names: PIP; Prolyl aminopeptidase; PAP [H]

Number of amino acids: Translated: 292; Mature: 291

Protein sequence:

>292_residues
MSFSLHSRGYYPTGDGHQLYWERHGVPGHEPVFFLHGGPGGRFSRHHLQFFDQGRFDIILFDQRGCGRSTPYGELRDNTT
GLCVEDIDALRQHFGFEKISVLGVSWGSWLAIQYQQRYPQHLLKSTLVSLFVPFAANVRAYDQALNDGLAQSPQMSPGQR
ASHIYRILGEGCPSQQHRAAIEWLNAVLRRSGQTICPDTLERFVDQEAVLAIRLELHYHLQNYCFTPKDENLTLDDNTLL
IQGIRDTHGMASVRWLRQRMNIHCRLLHAGHNAFENAILKAVRRAVKREIEG

Sequences:

>Translated_292_residues
MSFSLHSRGYYPTGDGHQLYWERHGVPGHEPVFFLHGGPGGRFSRHHLQFFDQGRFDIILFDQRGCGRSTPYGELRDNTT
GLCVEDIDALRQHFGFEKISVLGVSWGSWLAIQYQQRYPQHLLKSTLVSLFVPFAANVRAYDQALNDGLAQSPQMSPGQR
ASHIYRILGEGCPSQQHRAAIEWLNAVLRRSGQTICPDTLERFVDQEAVLAIRLELHYHLQNYCFTPKDENLTLDDNTLL
IQGIRDTHGMASVRWLRQRMNIHCRLLHAGHNAFENAILKAVRRAVKREIEG
>Mature_291_residues
SFSLHSRGYYPTGDGHQLYWERHGVPGHEPVFFLHGGPGGRFSRHHLQFFDQGRFDIILFDQRGCGRSTPYGELRDNTTG
LCVEDIDALRQHFGFEKISVLGVSWGSWLAIQYQQRYPQHLLKSTLVSLFVPFAANVRAYDQALNDGLAQSPQMSPGQRA
SHIYRILGEGCPSQQHRAAIEWLNAVLRRSGQTICPDTLERFVDQEAVLAIRLELHYHLQNYCFTPKDENLTLDDNTLLI
QGIRDTHGMASVRWLRQRMNIHCRLLHAGHNAFENAILKAVRRAVKREIEG

Specific function: Specifically catalyzes the removal of N-terminal proline residues from peptides [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S33 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR005944
- InterPro:   IPR002410 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.4.11.5 [H]

Molecular weight: Translated: 33414; Mature: 33283

Theoretical pI: Translated: 8.18; Mature: 8.18

Prosite motif: PS00120 LIPASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFSLHSRGYYPTGDGHQLYWERHGVPGHEPVFFLHGGPGGRFSRHHLQFFDQGRFDIIL
CCCCCCCCCCCCCCCCCEEEEEECCCCCCCCEEEEECCCCCCCCHHHHHHHCCCCEEEEE
FDQRGCGRSTPYGELRDNTTGLCVEDIDALRQHFGFEKISVLGVSWGSWLAIQYQQRYPQ
ECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEECCCCEEEEEHHHHHHH
HLLKSTLVSLFVPFAANVRAYDQALNDGLAQSPQMSPGQRASHIYRILGEGCPSQQHRAA
HHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHH
IEWLNAVLRRSGQTICPDTLERFVDQEAVLAIRLELHYHLQNYCFTPKDENLTLDDNTLL
HHHHHHHHHHCCCCCCHHHHHHHHCCHHEEEEEEHHHHHHHHCCCCCCCCCEEECCCEEE
IQGIRDTHGMASVRWLRQRMNIHCRLLHAGHNAFENAILKAVRRAVKREIEG
EEECCCCCHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SFSLHSRGYYPTGDGHQLYWERHGVPGHEPVFFLHGGPGGRFSRHHLQFFDQGRFDIIL
CCCCCCCCCCCCCCCCEEEEEECCCCCCCCEEEEECCCCCCCCHHHHHHHCCCCEEEEE
FDQRGCGRSTPYGELRDNTTGLCVEDIDALRQHFGFEKISVLGVSWGSWLAIQYQQRYPQ
ECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEECCCCEEEEEHHHHHHH
HLLKSTLVSLFVPFAANVRAYDQALNDGLAQSPQMSPGQRASHIYRILGEGCPSQQHRAA
HHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHH
IEWLNAVLRRSGQTICPDTLERFVDQEAVLAIRLELHYHLQNYCFTPKDENLTLDDNTLL
HHHHHHHHHHCCCCCCHHHHHHHHCCHHEEEEEEHHHHHHHHCCCCCCCCCEEECCCEEE
IQGIRDTHGMASVRWLRQRMNIHCRLLHAGHNAFENAILKAVRRAVKREIEG
EEECCCCCHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9348090; 11011150; 10467172 [H]