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The map label for this gene is icd [H]

Identifier: 77459816

GI number: 77459816

Start: 4062001

End: 4064226

Strand: Direct

Name: icd [H]

Synonym: Pfl01_3594

Alternate gene names: 77459816

Gene position: 4062001-4064226 (Clockwise)

Preceding gene: 77459814

Following gene: 77459817

Centisome position: 63.09

GC content: 60.56

Gene sequence:

>2226_bases
ATGCCCACCCGCTCGAAGATCATCTATACCTTCACCGACGAAGCTCCAGCCCTCGCCACCTATTCCCTGCTGCCGATCAT
CGAGGCCTACACCGCCTCGGCCGATATCGCCGTGGAAACCCGCGATATCTCTCTTGCAGCACGCATTCTGGCCAGCTTCC
CCGAGCAACTGGGCGACAAAGCCGTAGCCGACCACCTCGCCGAACTGGGCGACCTGGCCGTTACGCCTGAAGCCAACATC
ATCAAGCTGCCGAACATCAGCGCTTCGGTTCCGCAGTTGCAAGCCGCGATCAAAGAACTGCAAGCCCAGGGCTACAACCT
GCCGGACTACCCGGAATCCGTGACCAACGACGCCGAAAAAGAAGCCAAGGCGCGTTACGACAAGGTCAAGGGCAGCGCCG
TGAACCCGGTTCTGCGTGAAGGCAACTCCGACCGTCGTGCGCCGCTGTCGGTCAAGAACTACGCTCGCAAGCACCCGCAC
AAAATGGGCGCCTGGGCCAAAGACTCCAAGTCTCATGTCGCTCACATGAGCACCGGCGATTTCTATGGCAGCGAAAAAGC
TGTCCTGATCGACGCCGCTGACGCCGTGAAGATCGAACTGATCGCCAAAGACGGCACCGCGACCGTCCTGAAAGAAAAGA
CCACCGTTCAGGCGGGCGAGATCCTCGACTGCTCCGTGATGAGCAAAAAGGCCCTGCGCGCGTTCATCGCCGCCGAAATC
GACAGCGCCAAGCAGCAAGGCGTGCTGCTGTCGGTTCACCTGAAAGCCACCATGATGAAGGTCTCCGACCCGATCATGTT
CGGCCAGATCGTTGCCGAGTTCTACAAAGACGCCCTGACCAAGCACGCCGACGTGCTGGCCGAGATCGGCTTCAACCTGA
ACAACGGCATCGGCGACCTGTACGCCCGCATCAAATCCCTGCCGGCCGAACAACAAGCCCAGATCGAAGCTGACGTGCAG
GCTGTCTACGCCGTTCGTCCGTCGCTGGCGATGGTCAACTCCGACAAAGGCATCACCAACCTGCACGTGCCGAGCGACGT
TATCGTCGACGCCTCGATGCCGGCCATGATCCGTGACTCCGGCAAGATGTGGGGCACTGACGGCCAGTTGCACGACACCA
AGGCTGTGATCCCGGATCGCTGCTACGCCACCATCTACCAGGCCGTGATCGAAGATTGCAAAGCCAATGGCGCTTTCGAT
CCGACCACCATGGGCAGCGTGCCAAACGTTGGCCTGATGGCTAAAAAGGCTGAAGAGTACGGCTCCCACGACAAAACCTT
CCAGATCAAGGCCGACGGCGTGGTTCGCGTGACCGACAGCAAAGGCACCCTGCTGATGGAACAGGCTGTTGAAGCCGGCG
ACATCTTCCGCATGTGCCAGACCAAAGACGCGCCGATCCAGGACTGGGTCAAACTGGCCGTCAACCGTGCTCGCGCAAGC
GCAACTCCAGCCATTTTCTGGCTGGACCCGATGCGCGCCCACGACGGCGTGGTGATCGAGAAGGTTCAGGCTTACCTGAA
GGATCACGACACCGCCGGTCTGGACATCCAGATCATGGCGCCGGTCGATGCCATGAAATACACCCTGCAGCGCACCCGCG
AAGGCAAGGACACCATTTCGGTGACCGGCAACGTACTGCGCGACTACCTGACAGACCTGTTCCCGATCATGGAACTGGGC
ACCAGCGCCAAGATGCTGTCGATCGTGCCGCTGATGAACGGCGGTGGCCTGTTCGAAACCGGCGCCGGCGGTTCGGCTCC
GAAGCACGTGCAGCAACTGGTCGAAGAGAACTTCCTGCGCTGGGATTCGCTGGGTGAATTCTTGGCCCTGGCCGCTTCTC
TCGAGCACCTGGGTGTTAACTACAACAACCCGAAAGCGCTGGTTCTGTCCAAGACCCTGGATCAGGCCACCGGCCAGTTC
CTCGACAACAACAAGTCGCCATCGCGCAAAGTCGGCAACATCGACAACCGCGGCAGCCACTTCTACCTGGCGATGTACTG
GGCACAAGCCCTGGCCGCCCAGACTGAAGACGCTGCACTGCAAGCGCAGTTCGCGACTCTGGCCAAGACCCTGACCGAGA
ACGAAGCGACCATCGTCGCCGAGCTCAACGCCGTTCAAGGCAAGCCAGTGGACATCGGCGGTTACTACCACGCCGATGCC
GAGCTGATCAGCAAGGCCATGCGCCCAAGCGCAACCCTCAACGCGGCGATTGCTGCGCTGGTATAA

Upstream 100 bases:

>100_bases
TCGACATTCGGTTCATGGATGACTTTGAACGAACGCGCTTACCCGGCGCCCCTCGAGTTTCTGCGCACGCTTTAGCAAAG
AAGAGAGAGTTAATCCGAAT

Downstream 100 bases:

>100_bases
GGTTGTAAAGGGAACATCACAAACCCCGGCCTCGTGCCGGGGTTTGTGTTTCTGCCTTTCGCCCAGGAGATTCAATCAAT
GCAATGGCTCCCCCACATCA

Product: isocitrate dehydrogenase (NADP+)

Products: NA

Alternate protein names: IDH; Oxalosuccinate decarboxylase [H]

Number of amino acids: Translated: 741; Mature: 740

Protein sequence:

>741_residues
MPTRSKIIYTFTDEAPALATYSLLPIIEAYTASADIAVETRDISLAARILASFPEQLGDKAVADHLAELGDLAVTPEANI
IKLPNISASVPQLQAAIKELQAQGYNLPDYPESVTNDAEKEAKARYDKVKGSAVNPVLREGNSDRRAPLSVKNYARKHPH
KMGAWAKDSKSHVAHMSTGDFYGSEKAVLIDAADAVKIELIAKDGTATVLKEKTTVQAGEILDCSVMSKKALRAFIAAEI
DSAKQQGVLLSVHLKATMMKVSDPIMFGQIVAEFYKDALTKHADVLAEIGFNLNNGIGDLYARIKSLPAEQQAQIEADVQ
AVYAVRPSLAMVNSDKGITNLHVPSDVIVDASMPAMIRDSGKMWGTDGQLHDTKAVIPDRCYATIYQAVIEDCKANGAFD
PTTMGSVPNVGLMAKKAEEYGSHDKTFQIKADGVVRVTDSKGTLLMEQAVEAGDIFRMCQTKDAPIQDWVKLAVNRARAS
ATPAIFWLDPMRAHDGVVIEKVQAYLKDHDTAGLDIQIMAPVDAMKYTLQRTREGKDTISVTGNVLRDYLTDLFPIMELG
TSAKMLSIVPLMNGGGLFETGAGGSAPKHVQQLVEENFLRWDSLGEFLALAASLEHLGVNYNNPKALVLSKTLDQATGQF
LDNNKSPSRKVGNIDNRGSHFYLAMYWAQALAAQTEDAALQAQFATLAKTLTENEATIVAELNAVQGKPVDIGGYYHADA
ELISKAMRPSATLNAAIAALV

Sequences:

>Translated_741_residues
MPTRSKIIYTFTDEAPALATYSLLPIIEAYTASADIAVETRDISLAARILASFPEQLGDKAVADHLAELGDLAVTPEANI
IKLPNISASVPQLQAAIKELQAQGYNLPDYPESVTNDAEKEAKARYDKVKGSAVNPVLREGNSDRRAPLSVKNYARKHPH
KMGAWAKDSKSHVAHMSTGDFYGSEKAVLIDAADAVKIELIAKDGTATVLKEKTTVQAGEILDCSVMSKKALRAFIAAEI
DSAKQQGVLLSVHLKATMMKVSDPIMFGQIVAEFYKDALTKHADVLAEIGFNLNNGIGDLYARIKSLPAEQQAQIEADVQ
AVYAVRPSLAMVNSDKGITNLHVPSDVIVDASMPAMIRDSGKMWGTDGQLHDTKAVIPDRCYATIYQAVIEDCKANGAFD
PTTMGSVPNVGLMAKKAEEYGSHDKTFQIKADGVVRVTDSKGTLLMEQAVEAGDIFRMCQTKDAPIQDWVKLAVNRARAS
ATPAIFWLDPMRAHDGVVIEKVQAYLKDHDTAGLDIQIMAPVDAMKYTLQRTREGKDTISVTGNVLRDYLTDLFPIMELG
TSAKMLSIVPLMNGGGLFETGAGGSAPKHVQQLVEENFLRWDSLGEFLALAASLEHLGVNYNNPKALVLSKTLDQATGQF
LDNNKSPSRKVGNIDNRGSHFYLAMYWAQALAAQTEDAALQAQFATLAKTLTENEATIVAELNAVQGKPVDIGGYYHADA
ELISKAMRPSATLNAAIAALV
>Mature_740_residues
PTRSKIIYTFTDEAPALATYSLLPIIEAYTASADIAVETRDISLAARILASFPEQLGDKAVADHLAELGDLAVTPEANII
KLPNISASVPQLQAAIKELQAQGYNLPDYPESVTNDAEKEAKARYDKVKGSAVNPVLREGNSDRRAPLSVKNYARKHPHK
MGAWAKDSKSHVAHMSTGDFYGSEKAVLIDAADAVKIELIAKDGTATVLKEKTTVQAGEILDCSVMSKKALRAFIAAEID
SAKQQGVLLSVHLKATMMKVSDPIMFGQIVAEFYKDALTKHADVLAEIGFNLNNGIGDLYARIKSLPAEQQAQIEADVQA
VYAVRPSLAMVNSDKGITNLHVPSDVIVDASMPAMIRDSGKMWGTDGQLHDTKAVIPDRCYATIYQAVIEDCKANGAFDP
TTMGSVPNVGLMAKKAEEYGSHDKTFQIKADGVVRVTDSKGTLLMEQAVEAGDIFRMCQTKDAPIQDWVKLAVNRARASA
TPAIFWLDPMRAHDGVVIEKVQAYLKDHDTAGLDIQIMAPVDAMKYTLQRTREGKDTISVTGNVLRDYLTDLFPIMELGT
SAKMLSIVPLMNGGGLFETGAGGSAPKHVQQLVEENFLRWDSLGEFLALAASLEHLGVNYNNPKALVLSKTLDQATGQFL
DNNKSPSRKVGNIDNRGSHFYLAMYWAQALAAQTEDAALQAQFATLAKTLTENEATIVAELNAVQGKPVDIGGYYHADAE
LISKAMRPSATLNAAIAALV

Specific function: Unknown

COG id: COG2838

COG function: function code C; Monomeric isocitrate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the monomeric-type IDH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001804
- InterPro:   IPR004436 [H]

Pfam domain/function: PF03971 IDH [H]

EC number: =1.1.1.42 [H]

Molecular weight: Translated: 80061; Mature: 79930

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: PS00334 MYB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTRSKIIYTFTDEAPALATYSLLPIIEAYTASADIAVETRDISLAARILASFPEQLGDK
CCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHHHHCHH
AVADHLAELGDLAVTPEANIIKLPNISASVPQLQAAIKELQAQGYNLPDYPESVTNDAEK
HHHHHHHHHCCEEECCCCCEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHCCHHHH
EAKARYDKVKGSAVNPVLREGNSDRRAPLSVKNYARKHPHKMGAWAKDSKSHVAHMSTGD
HHHHHHHHCCCCCCCHHHHCCCCCCCCCCCHHHHHHHCCHHCCCCCCCCCCCEEEECCCC
FYGSEKAVLIDAADAVKIELIAKDGTATVLKEKTTVQAGEILDCSVMSKKALRAFIAAEI
CCCCCCEEEEECCCCEEEEEEECCCCEEEEECCCCCCCCCEEEHHHHHHHHHHHHHHHHH
DSAKQQGVLLSVHLKATMMKVSDPIMFGQIVAEFYKDALTKHADVLAEIGFNLNNGIGDL
HHHHHCCEEEEEEEHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
YARIKSLPAEQQAQIEADVQAVYAVRPSLAMVNSDKGITNLHVPSDVIVDASMPAMIRDS
HHHHHHCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEECCCCEEEECCCCHHHHCC
GKMWGTDGQLHDTKAVIPDRCYATIYQAVIEDCKANGAFDPTTMGSVPNVGLMAKKAEEY
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHH
GSHDKTFQIKADGVVRVTDSKGTLLMEQAVEAGDIFRMCQTKDAPIQDWVKLAVNRARAS
CCCCCEEEEEECCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCC
ATPAIFWLDPMRAHDGVVIEKVQAYLKDHDTAGLDIQIMAPVDAMKYTLQRTREGKDTIS
CCCEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHCCCCCEEE
VTGNVLRDYLTDLFPIMELGTSAKMLSIVPLMNGGGLFETGAGGSAPKHVQQLVEENFLR
HHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCEEECCCCCCCHHHHHHHHHHHHHH
WDSLGEFLALAASLEHLGVNYNNPKALVLSKTLDQATGQFLDNNKSPSRKVGNIDNRGSH
HHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHCCCCCCCCCCCCCCCCCCE
FYLAMYWAQALAAQTEDAALQAQFATLAKTLTENEATIVAELNAVQGKPVDIGGYYHADA
EEHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCEEECCEEECCH
ELISKAMRPSATLNAAIAALV
HHHHHHHCCCHHHHHHHHHCC
>Mature Secondary Structure 
PTRSKIIYTFTDEAPALATYSLLPIIEAYTASADIAVETRDISLAARILASFPEQLGDK
CCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHHHHCHH
AVADHLAELGDLAVTPEANIIKLPNISASVPQLQAAIKELQAQGYNLPDYPESVTNDAEK
HHHHHHHHHCCEEECCCCCEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHCCHHHH
EAKARYDKVKGSAVNPVLREGNSDRRAPLSVKNYARKHPHKMGAWAKDSKSHVAHMSTGD
HHHHHHHHCCCCCCCHHHHCCCCCCCCCCCHHHHHHHCCHHCCCCCCCCCCCEEEECCCC
FYGSEKAVLIDAADAVKIELIAKDGTATVLKEKTTVQAGEILDCSVMSKKALRAFIAAEI
CCCCCCEEEEECCCCEEEEEEECCCCEEEEECCCCCCCCCEEEHHHHHHHHHHHHHHHHH
DSAKQQGVLLSVHLKATMMKVSDPIMFGQIVAEFYKDALTKHADVLAEIGFNLNNGIGDL
HHHHHCCEEEEEEEHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
YARIKSLPAEQQAQIEADVQAVYAVRPSLAMVNSDKGITNLHVPSDVIVDASMPAMIRDS
HHHHHHCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEECCCCEEEECCCCHHHHCC
GKMWGTDGQLHDTKAVIPDRCYATIYQAVIEDCKANGAFDPTTMGSVPNVGLMAKKAEEY
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHH
GSHDKTFQIKADGVVRVTDSKGTLLMEQAVEAGDIFRMCQTKDAPIQDWVKLAVNRARAS
CCCCCEEEEEECCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCC
ATPAIFWLDPMRAHDGVVIEKVQAYLKDHDTAGLDIQIMAPVDAMKYTLQRTREGKDTIS
CCCEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHCCCCCEEE
VTGNVLRDYLTDLFPIMELGTSAKMLSIVPLMNGGGLFETGAGGSAPKHVQQLVEENFLR
HHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCEEECCCCCCCHHHHHHHHHHHHHH
WDSLGEFLALAASLEHLGVNYNNPKALVLSKTLDQATGQFLDNNKSPSRKVGNIDNRGSH
HHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHCCCCCCCCCCCCCCCCCCE
FYLAMYWAQALAAQTEDAALQAQFATLAKTLTENEATIVAELNAVQGKPVDIGGYYHADA
EEHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCEEECCEEECCH
ELISKAMRPSATLNAAIAALV
HHHHHHHCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12005040; 4149369; 12467571 [H]