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The map label for this gene is lpxA [H]

Identifier: 77457340

GI number: 77457340

Start: 1287145

End: 1287921

Strand: Direct

Name: lpxA [H]

Synonym: Pfl01_1113

Alternate gene names: 77457340

Gene position: 1287145-1287921 (Clockwise)

Preceding gene: 77457339

Following gene: 77457341

Centisome position: 19.99

GC content: 61.0

Gene sequence:

>777_bases
ATGAGTTTGATTGACCCTCGCGCAATCATCGATCCATCGGCCGTCCTGGCCGATGGCGTCGAGGTCGGCCCGTGGTCGAT
CATCGGTGCAGGTGTGGAAATCGGCGAGGGAACGGTCATCGGGCCACACGTGATCCTCAAAGGTCCGACCCGTATCGGCA
AGCACAACCGCATCTACCAGTTTTCCTCGGTAGGCGAAGACACGCCGGACCTGAAATACAAGGGCGAAGAAACCCGCCTG
GTGATCGGTGACCACAACGTCATCCGCGAAGGCGTGACGATTCATCGTGGCACCGTTCAGGATCGTTCCGAAACGACCCT
GGGTGATCACAACCTGATCATGGCCTATGCCCACATCGGACATGACAGCGTCATCGGCAACCACTGCATCCTGGTCAACA
ACACCGCGCTGGCCGGCCATGTGCACGTTGATGACTGGGCAATCCTGTCCGGTTTCACCCTGGTGCATCAGTATTGCCAC
ATCGGCGCCCACAGCTTTTCCGGCATGGGCACGGCGATCGGCAAGGACGTTCCGGCGTTCGTCACCGTATTCGGCAACCC
GGCCGAAGCGCGCAGCATGAACTTCGAAGGCATGCGTCGTCGTGGTTTCAGCGAAGACGCCATTCACGCCCTGCGCCGTG
CGTACAAAACGGTGTATCGCCAGGGCCTGACCGTCGAGCAGGCGCTGGCCGAGCTGGCCGAGCCGTCTGCACAGTTCCCG
GAAGTCGCGATGTTCCGTGACTCCATCCAGTCGTCGACCCGCGGCATCACCCGCTGA

Upstream 100 bases:

>100_bases
TCATCAGTTGCAAGCGTCAGATCTGGAAGTTCGAATGCCAGGCTTCGGTCGATGGCAAACCGGTCTGCTCGGCTGAAATC
ATCTGTGCGGAACGCAAGCT

Downstream 100 bases:

>100_bases
CCATGGCCAATCTGCGTATTGCGCTGGTGGCGGGTGAGGCTTCCGGTGACATTCTGGGCGCCGGTCTCATGCGCGCCCTC
AAGGCACAGCACCCTGCGGT

Product: UDP-N-acetylglucosamine acyltransferase

Products: NA

Alternate protein names: UDP-N-acetylglucosamine acyltransferase [H]

Number of amino acids: Translated: 258; Mature: 257

Protein sequence:

>258_residues
MSLIDPRAIIDPSAVLADGVEVGPWSIIGAGVEIGEGTVIGPHVILKGPTRIGKHNRIYQFSSVGEDTPDLKYKGEETRL
VIGDHNVIREGVTIHRGTVQDRSETTLGDHNLIMAYAHIGHDSVIGNHCILVNNTALAGHVHVDDWAILSGFTLVHQYCH
IGAHSFSGMGTAIGKDVPAFVTVFGNPAEARSMNFEGMRRRGFSEDAIHALRRAYKTVYRQGLTVEQALAELAEPSAQFP
EVAMFRDSIQSSTRGITR

Sequences:

>Translated_258_residues
MSLIDPRAIIDPSAVLADGVEVGPWSIIGAGVEIGEGTVIGPHVILKGPTRIGKHNRIYQFSSVGEDTPDLKYKGEETRL
VIGDHNVIREGVTIHRGTVQDRSETTLGDHNLIMAYAHIGHDSVIGNHCILVNNTALAGHVHVDDWAILSGFTLVHQYCH
IGAHSFSGMGTAIGKDVPAFVTVFGNPAEARSMNFEGMRRRGFSEDAIHALRRAYKTVYRQGLTVEQALAELAEPSAQFP
EVAMFRDSIQSSTRGITR
>Mature_257_residues
SLIDPRAIIDPSAVLADGVEVGPWSIIGAGVEIGEGTVIGPHVILKGPTRIGKHNRIYQFSSVGEDTPDLKYKGEETRLV
IGDHNVIREGVTIHRGTVQDRSETTLGDHNLIMAYAHIGHDSVIGNHCILVNNTALAGHVHVDDWAILSGFTLVHQYCHI
GAHSFSGMGTAIGKDVPAFVTVFGNPAEARSMNFEGMRRRGFSEDAIHALRRAYKTVYRQGLTVEQALAELAEPSAQFPE
VAMFRDSIQSSTRGITR

Specific function: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell [H]

COG id: COG1043

COG function: function code M; Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family. LpxA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786378, Length=262, Percent_Identity=50.763358778626, Blast_Score=268, Evalue=2e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001451
- InterPro:   IPR018357
- InterPro:   IPR010137
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00132 Hexapep [H]

EC number: =2.3.1.129 [H]

Molecular weight: Translated: 28014; Mature: 27883

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLIDPRAIIDPSAVLADGVEVGPWSIIGAGVEIGEGTVIGPHVILKGPTRIGKHNRIYQ
CCCCCCCHHCCCHHHHHCCCCCCCCEEEECCEEECCCEEECCEEEEECCCCCCCCCCEEE
FSSVGEDTPDLKYKGEETRLVIGDHNVIREGVTIHRGTVQDRSETTLGDHNLIMAYAHIG
ECCCCCCCCCCEECCCCCEEEECCCHHHHCCCEEEECCCCCCCCCCCCCCCEEEEEEECC
HDSVIGNHCILVNNTALAGHVHVDDWAILSGFTLVHQYCHIGAHSFSGMGTAIGKDVPAF
CCCEECCEEEEEECCEEEEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCCCCEE
VTVFGNPAEARSMNFEGMRRRGFSEDAIHALRRAYKTVYRQGLTVEQALAELAEPSAQFP
EEEECCCHHHHCCCCHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCC
EVAMFRDSIQSSTRGITR
HHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SLIDPRAIIDPSAVLADGVEVGPWSIIGAGVEIGEGTVIGPHVILKGPTRIGKHNRIYQ
CCCCCCHHCCCHHHHHCCCCCCCCEEEECCEEECCCEEECCEEEEECCCCCCCCCCEEE
FSSVGEDTPDLKYKGEETRLVIGDHNVIREGVTIHRGTVQDRSETTLGDHNLIMAYAHIG
ECCCCCCCCCCEECCCCCEEEECCCHHHHCCCEEEECCCCCCCCCCCCCCCEEEEEEECC
HDSVIGNHCILVNNTALAGHVHVDDWAILSGFTLVHQYCHIGAHSFSGMGTAIGKDVPAF
CCCEECCEEEEEECCEEEEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCCCCEE
VTVFGNPAEARSMNFEGMRRRGFSEDAIHALRRAYKTVYRQGLTVEQALAELAEPSAQFP
EEEECCCHHHHCCCCHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCC
EVAMFRDSIQSSTRGITR
HHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA