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The map label for this gene is fabZ [H]

Identifier: 77457339

GI number: 77457339

Start: 1286708

End: 1287148

Strand: Direct

Name: fabZ [H]

Synonym: Pfl01_1112

Alternate gene names: 77457339

Gene position: 1286708-1287148 (Clockwise)

Preceding gene: 77457338

Following gene: 77457340

Centisome position: 19.98

GC content: 56.46

Gene sequence:

>441_bases
ATGATGGACATCAACGAGATTCGCGAATACCTGCCTCACCGTTACCCGTTCCTGCTGGTGGATCGGGTAGTGGAGCTGGA
TACGGAAGGCAAGCGCATTCGCGCCTACAAGAATGTCAGCATCAACGAGCCGTTCTTCAACGGTCACTTCCCGGCGCACC
CGATCATGCCGGGCGTGCTGATCATCGAAGCCATGGCTCAGGCTGCCGGGATCCTCGGTTTCAAGATGCTTGACGTGAAA
CCGGCCGACGGCACCCTTTATTACTTCGTTGGCTCCGACAAACTGCGTTTCCGCCAGCCAGTGCTGCCGGGCGATCAGTT
GATCCTCGAAGCCAAGTTCATCAGTTGCAAGCGTCAGATCTGGAAGTTCGAATGCCAGGCTTCGGTCGATGGCAAACCGG
TCTGCTCGGCTGAAATCATCTGTGCGGAACGCAAGCTATGA

Upstream 100 bases:

>100_bases
TTCCATATCAAGTGTGCACAGCCTCTGGACTGCCTCCTTGATTTGCTAGAGGAGTGCGCGTCAGTCGCGCTCCCAATCTT
TACATAGGCTTCCCCCCGAA

Downstream 100 bases:

>100_bases
GTTTGATTGACCCTCGCGCAATCATCGATCCATCGGCCGTCCTGGCCGATGGCGTCGAGGTCGGCCCGTGGTCGATCATC
GGTGCAGGTGTGGAAATCGG

Product: (3R)-hydroxymyristoyl-ACP dehydratase

Products: NA

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase [H]

Number of amino acids: Translated: 146; Mature: 146

Protein sequence:

>146_residues
MMDINEIREYLPHRYPFLLVDRVVELDTEGKRIRAYKNVSINEPFFNGHFPAHPIMPGVLIIEAMAQAAGILGFKMLDVK
PADGTLYYFVGSDKLRFRQPVLPGDQLILEAKFISCKRQIWKFECQASVDGKPVCSAEIICAERKL

Sequences:

>Translated_146_residues
MMDINEIREYLPHRYPFLLVDRVVELDTEGKRIRAYKNVSINEPFFNGHFPAHPIMPGVLIIEAMAQAAGILGFKMLDVK
PADGTLYYFVGSDKLRFRQPVLPGDQLILEAKFISCKRQIWKFECQASVDGKPVCSAEIICAERKL
>Mature_146_residues
MMDINEIREYLPHRYPFLLVDRVVELDTEGKRIRAYKNVSINEPFFNGHFPAHPIMPGVLIIEAMAQAAGILGFKMLDVK
PADGTLYYFVGSDKLRFRQPVLPGDQLILEAKFISCKRQIWKFECQASVDGKPVCSAEIICAERKL

Specific function: Involved in saturated fatty acids biosynthesis [H]

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786377, Length=144, Percent_Identity=56.9444444444444, Blast_Score=169, Evalue=9e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013114
- InterPro:   IPR010084 [H]

Pfam domain/function: PF07977 FabA [H]

EC number: 4.2.1.-

Molecular weight: Translated: 16659; Mature: 16659

Theoretical pI: Translated: 7.95; Mature: 7.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMDINEIREYLPHRYPFLLVDRVVELDTEGKRIRAYKNVSINEPFFNGHFPAHPIMPGVL
CCCHHHHHHHCCCCCCHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHH
IIEAMAQAAGILGFKMLDVKPADGTLYYFVGSDKLRFRQPVLPGDQLILEAKFISCKRQI
HHHHHHHHHHHCEEEEEEEECCCCEEEEEECCCCEEEECCCCCCCCEEEEHHHHHHHHHH
WKFECQASVDGKPVCSAEIICAERKL
HEEEEECCCCCCCCCCEEEEEECCCC
>Mature Secondary Structure
MMDINEIREYLPHRYPFLLVDRVVELDTEGKRIRAYKNVSINEPFFNGHFPAHPIMPGVL
CCCHHHHHHHCCCCCCHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHH
IIEAMAQAAGILGFKMLDVKPADGTLYYFVGSDKLRFRQPVLPGDQLILEAKFISCKRQI
HHHHHHHHHHHCEEEEEEEECCCCEEEEEECCCCEEEECCCCCCCCEEEEHHHHHHHHHH
WKFECQASVDGKPVCSAEIICAERKL
HEEEEECCCCCCCCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA