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The map label for this gene is yaeL [C]

Identifier: 77457335

GI number: 77457335

Start: 1281176

End: 1282528

Strand: Direct

Name: yaeL [C]

Synonym: Pfl01_1108

Alternate gene names: 77457335

Gene position: 1281176-1282528 (Clockwise)

Preceding gene: 77457334

Following gene: 77457336

Centisome position: 19.9

GC content: 60.31

Gene sequence:

>1353_bases
ATGAGCGCGCTCTATATGATTGCCGGCACCCTGATCGCTCTGGGTGTGCTGGTCACCTTTCACGAATTCGGCCATTTCTG
GGTCGCGCGTCGCTGTGGCGTCAAGGTTCTGCGTTTCTCCGTGGGCTTCGGCATGCCGCTGCTGCGCTGGCATGACAAGC
AGGGCACTGAGTTCGTGGTCGCGGCCATTCCGCTGGGTGGCTACGTCAAAATGCTTGATGAGCGCGAAGGCGAAGTACCG
GCCGATCAGCTTCATCAGTCATTCAATCGCAAGTCCGTACGTCAGCGTATCGCCATCGTCGCGGCCGGCCCTGTGGCCAA
CTTCCTGCTTGCGCTGGTGTTCTTCTGGGTGCTGGCGATGCTCGGCAGTGAACAGATTCGCCCGGTCATCGGTTCGGTGG
AGTCCGGCAGCATCGCCGCTACGGCTGGGCTGAGCGCCGGTCAGGAAATCGTCGCGATCGACGGCGAGCCGACCTCGGGC
TGGGCGGCGGTCAACCTGCAGTTGGTGCGACGTCTCGGGGAAAGCGGTTCCTTGCAGGTACTGGTGCGCGAGCAGGGCTC
TACGGCTGATTCGCCTCGTGAACTGGCACTCGATAAATGGCTCAAGGGGGCTGACGAGCCGGATCCGATTCGCTCTCTCG
GCATTCGCCCTTGGCGCCCGGCATTGCCGCCGGTGCTGGCCGAACTTGATCCCAAAGGTCCGGCCCAGGCAGCCGGGCTG
AAAACCGGCGATCGTCTGCTGACACTGGATGGCAAGGCGCTGGATGACTGGCAGCAGGTGGTCGACACCGTTCGTACGCG
TCCTGATACCAAAATCGTGCTGCGCGTCGAGCGCGACGGTGTTCAAATCGACGTCCCTGTGACATTGGCTGCACGTGGCG
AGAAGAAGTCGCCAAGCGGTTACCTGGGGGCGGGCGTCAAGGCTGTCGACTGGCCACCGGAAATGATCCGCGAGGTCAGC
TACGGTCCTTTGGCGGCGATTGGCGAGGGTGCCCGTCGTACCTGGACCATGAGCGTCCTGACGCTGGATTCACTGAAGAA
AATGCTCTTCGGCGAGCTCTCGGTAAAAAACTTGAGTGGACCGATAACCATTGCTAAAGTGGCGGGCGCTTCTGCCCAGT
CGGGCGTCGCTGATTTCCTGAATTTCCTTGCTTATCTGAGTATTAGCCTGGGGGTTCTGAATTTGCTGCCCATTCCTGTA
CTGGATGGGGGGCATTTGTTGTTTTATCTGATCGAGTGGGCGCGTGGTCGTCCCTTGTCGGATCGGGTGCAAGGTTGGGG
GATACAGATCGGTATCAGTTTGGTGGTCGGGGTGATGTTGCTTGCTCTGGTCAACGATCTGGGTCGTCTGTAA

Upstream 100 bases:

>100_bases
CTGCCCGGACATTGGCCGGGCAGTGGTTGAGTCGTAACGGCCGATAGGTCTTGCAATACATGGCTTCACGCGGCACTGGA
CAGGATTGCGGAGAAAGTAG

Downstream 100 bases:

>100_bases
CGCTTCGCTGAATTGCGAATCTGCCGCATTTTGCGGCAGTTTGTTTATTGCCAGTTGGAATAAGAAAGGACTTCATGAAA
CGTCTGCTGCTAACTGCGGT

Product: peptidase RseP

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 450; Mature: 449

Protein sequence:

>450_residues
MSALYMIAGTLIALGVLVTFHEFGHFWVARRCGVKVLRFSVGFGMPLLRWHDKQGTEFVVAAIPLGGYVKMLDEREGEVP
ADQLHQSFNRKSVRQRIAIVAAGPVANFLLALVFFWVLAMLGSEQIRPVIGSVESGSIAATAGLSAGQEIVAIDGEPTSG
WAAVNLQLVRRLGESGSLQVLVREQGSTADSPRELALDKWLKGADEPDPIRSLGIRPWRPALPPVLAELDPKGPAQAAGL
KTGDRLLTLDGKALDDWQQVVDTVRTRPDTKIVLRVERDGVQIDVPVTLAARGEKKSPSGYLGAGVKAVDWPPEMIREVS
YGPLAAIGEGARRTWTMSVLTLDSLKKMLFGELSVKNLSGPITIAKVAGASAQSGVADFLNFLAYLSISLGVLNLLPIPV
LDGGHLLFYLIEWARGRPLSDRVQGWGIQIGISLVVGVMLLALVNDLGRL

Sequences:

>Translated_450_residues
MSALYMIAGTLIALGVLVTFHEFGHFWVARRCGVKVLRFSVGFGMPLLRWHDKQGTEFVVAAIPLGGYVKMLDEREGEVP
ADQLHQSFNRKSVRQRIAIVAAGPVANFLLALVFFWVLAMLGSEQIRPVIGSVESGSIAATAGLSAGQEIVAIDGEPTSG
WAAVNLQLVRRLGESGSLQVLVREQGSTADSPRELALDKWLKGADEPDPIRSLGIRPWRPALPPVLAELDPKGPAQAAGL
KTGDRLLTLDGKALDDWQQVVDTVRTRPDTKIVLRVERDGVQIDVPVTLAARGEKKSPSGYLGAGVKAVDWPPEMIREVS
YGPLAAIGEGARRTWTMSVLTLDSLKKMLFGELSVKNLSGPITIAKVAGASAQSGVADFLNFLAYLSISLGVLNLLPIPV
LDGGHLLFYLIEWARGRPLSDRVQGWGIQIGISLVVGVMLLALVNDLGRL
>Mature_449_residues
SALYMIAGTLIALGVLVTFHEFGHFWVARRCGVKVLRFSVGFGMPLLRWHDKQGTEFVVAAIPLGGYVKMLDEREGEVPA
DQLHQSFNRKSVRQRIAIVAAGPVANFLLALVFFWVLAMLGSEQIRPVIGSVESGSIAATAGLSAGQEIVAIDGEPTSGW
AAVNLQLVRRLGESGSLQVLVREQGSTADSPRELALDKWLKGADEPDPIRSLGIRPWRPALPPVLAELDPKGPAQAAGLK
TGDRLLTLDGKALDDWQQVVDTVRTRPDTKIVLRVERDGVQIDVPVTLAARGEKKSPSGYLGAGVKAVDWPPEMIREVSY
GPLAAIGEGARRTWTMSVLTLDSLKKMLFGELSVKNLSGPITIAKVAGASAQSGVADFLNFLAYLSISLGVLNLLPIPVL
DGGHLLFYLIEWARGRPLSDRVQGWGIQIGISLVVGVMLLALVNDLGRL

Specific function: Unknown

COG id: COG0750

COG function: function code M; Predicted membrane-associated Zn-dependent proteases 1

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1786373, Length=450, Percent_Identity=46.4444444444444, Blast_Score=380, Evalue=1e-107,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR004387
- InterPro:   IPR008915 [H]

Pfam domain/function: PF00595 PDZ; PF02163 Peptidase_M50 [H]

EC number: NA

Molecular weight: Translated: 48421; Mature: 48290

Theoretical pI: Translated: 8.93; Mature: 8.93

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSALYMIAGTLIALGVLVTFHEFGHFWVARRCGVKVLRFSVGFGMPLLRWHDKQGTEFVV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHCCCCHHHEEECCCCCEEEE
AAIPLGGYVKMLDEREGEVPADQLHQSFNRKSVRQRIAIVAAGPVANFLLALVFFWVLAM
EEECCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHEEEECCHHHHHHHHHHHHHHHHH
LGSEQIRPVIGSVESGSIAATAGLSAGQEIVAIDGEPTSGWAAVNLQLVRRLGESGSLQV
HCCCHHHHHHCCCCCCCEEEECCCCCCCEEEEECCCCCCCEEEHHHHHHHHHCCCCCEEE
LVREQGSTADSPRELALDKWLKGADEPDPIRSLGIRPWRPALPPVLAELDPKGPAQAAGL
EEEECCCCCCCHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCCCHHHHHCCCCCCCHHCCC
KTGDRLLTLDGKALDDWQQVVDTVRTRPDTKIVLRVERDGVQIDVPVTLAARGEKKSPSG
CCCCEEEEECCCCHHHHHHHHHHHHCCCCCEEEEEEECCCEEEEEEEEEEECCCCCCCCC
YLGAGVKAVDWPPEMIREVSYGPLAAIGEGARRTWTMSVLTLDSLKKMLFGELSVKNLSG
CCCCCCEECCCCHHHHHHCCCCCHHHHCCCCCCEEEEEEHHHHHHHHHHHCCCCCCCCCC
PITIAKVAGASAQSGVADFLNFLAYLSISLGVLNLLPIPVLDGGHLLFYLIEWARGRPLS
CEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEECCCHHHHHHHHHHCCCCCH
DRVQGWGIQIGISLVVGVMLLALVNDLGRL
HHHCCCCEEEHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SALYMIAGTLIALGVLVTFHEFGHFWVARRCGVKVLRFSVGFGMPLLRWHDKQGTEFVV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHCCCCHHHEEECCCCCEEEE
AAIPLGGYVKMLDEREGEVPADQLHQSFNRKSVRQRIAIVAAGPVANFLLALVFFWVLAM
EEECCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHEEEECCHHHHHHHHHHHHHHHHH
LGSEQIRPVIGSVESGSIAATAGLSAGQEIVAIDGEPTSGWAAVNLQLVRRLGESGSLQV
HCCCHHHHHHCCCCCCCEEEECCCCCCCEEEEECCCCCCCEEEHHHHHHHHHCCCCCEEE
LVREQGSTADSPRELALDKWLKGADEPDPIRSLGIRPWRPALPPVLAELDPKGPAQAAGL
EEEECCCCCCCHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCCCHHHHHCCCCCCCHHCCC
KTGDRLLTLDGKALDDWQQVVDTVRTRPDTKIVLRVERDGVQIDVPVTLAARGEKKSPSG
CCCCEEEEECCCCHHHHHHHHHHHHCCCCCEEEEEEECCCEEEEEEEEEEECCCCCCCCC
YLGAGVKAVDWPPEMIREVSYGPLAAIGEGARRTWTMSVLTLDSLKKMLFGELSVKNLSG
CCCCCCEECCCCHHHHHHCCCCCHHHHCCCCCCEEEEEEHHHHHHHHHHHCCCCCCCCCC
PITIAKVAGASAQSGVADFLNFLAYLSISLGVLNLLPIPVLDGGHLLFYLIEWARGRPLS
CEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEECCCHHHHHHHHHHCCCCCH
DRVQGWGIQIGISLVVGVMLLALVNDLGRL
HHHCCCCEEEHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]