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The map label for this gene is frr

Identifier: 77457331

GI number: 77457331

Start: 1277802

End: 1278359

Strand: Direct

Name: frr

Synonym: Pfl01_1104

Alternate gene names: 77457331

Gene position: 1277802-1278359 (Clockwise)

Preceding gene: 77457330

Following gene: 77457332

Centisome position: 19.85

GC content: 57.89

Gene sequence:

>558_bases
ATGATCAACGAAATCAAGAAAGACGCTAAAGAGCGCATGACGAAGTCCGTTGAGTCCCTGGCTCACAACTTCGGTCGTAT
CCGCACCGGTCAGGCGCACCCAAGCATCCTGGAGGGTGTGATGGTGCCTTACTACGGCGCTGACACCCCGATCAAGCAAG
TGGCCAACATCACCGTCAAGGACGCTCGTACCCTGCAAGTCGTTGCGTTCGAGCGCAACATGCTGGGCGCCGTCGACAAG
GCTATCGGCAGTGCAGGTCTGAATCTGAACCCGACCAACCTGGGTGAGCTGCTGCTGATCAGCATGCCGGCCCTGACCGA
AGAAACCCGTCGCGGTTTCACCAAGCAGGCGCGTGACGTGGCAGAAGACGCCCGTGTTGCCGTGCGCAACATCCGTCGCG
ATGCGAACAGCTCCCTGAAGGATCTGGTCAAGGAAAAGGAAATCAGCGAAGACGAAGAGCGTCGCGCCGCAGGCGAGATC
GACGATCTGACCAAGAAGTTCGTGGCTGAAATCGACGCCAAGCTGGCCGAGAAAGAAAAAGACCTGATGGCCGTATAA

Upstream 100 bases:

>100_bases
ACAAGATGCCGCTGCGCGTATTTAACATGAACAAGCCGGGCGCCCTGCTGAACATCGTGCATGGTGGCGCTGAAGGCACT
CTGATCGAGGAAGTCCAACA

Downstream 100 bases:

>100_bases
GGGTCGAGTTTTAAATGGACAAGACCAAGCAGACTGCGCCGTCCACGGTGCCGCGCCATGTCGCGATCATCATGGATGGC
AATAATCGCTGGGCGAAAAA

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MINEIKKDAKERMTKSVESLAHNFGRIRTGQAHPSILEGVMVPYYGADTPIKQVANITVKDARTLQVVAFERNMLGAVDK
AIGSAGLNLNPTNLGELLLISMPALTEETRRGFTKQARDVAEDARVAVRNIRRDANSSLKDLVKEKEISEDEERRAAGEI
DDLTKKFVAEIDAKLAEKEKDLMAV

Sequences:

>Translated_185_residues
MINEIKKDAKERMTKSVESLAHNFGRIRTGQAHPSILEGVMVPYYGADTPIKQVANITVKDARTLQVVAFERNMLGAVDK
AIGSAGLNLNPTNLGELLLISMPALTEETRRGFTKQARDVAEDARVAVRNIRRDANSSLKDLVKEKEISEDEERRAAGEI
DDLTKKFVAEIDAKLAEKEKDLMAV
>Mature_185_residues
MINEIKKDAKERMTKSVESLAHNFGRIRTGQAHPSILEGVMVPYYGADTPIKQVANITVKDARTLQVVAFERNMLGAVDK
AIGSAGLNLNPTNLGELLLISMPALTEETRRGFTKQARDVAEDARVAVRNIRRDANSSLKDLVKEKEISEDEERRAAGEI
DDLTKKFVAEIDAKLAEKEKDLMAV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family

Homologues:

Organism=Homo sapiens, GI20270317, Length=179, Percent_Identity=29.0502793296089, Blast_Score=68, Evalue=4e-12,
Organism=Escherichia coli, GI1786368, Length=183, Percent_Identity=49.7267759562842, Blast_Score=186, Evalue=1e-48,
Organism=Drosophila melanogaster, GI24661488, Length=179, Percent_Identity=27.3743016759777, Blast_Score=73, Evalue=1e-13,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): RRF_PSEPF (Q3KHA9)

Other databases:

- EMBL:   CP000094
- RefSeq:   YP_346836.1
- ProteinModelPortal:   Q3KHA9
- SMR:   Q3KHA9
- STRING:   Q3KHA9
- GeneID:   3716509
- GenomeReviews:   CP000094_GR
- KEGG:   pfo:Pfl01_1104
- eggNOG:   COG0233
- HOGENOM:   HBG533975
- OMA:   YYGAETP
- ProtClustDB:   PRK00083
- BioCyc:   PFLU205922:PFL_1104-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00040
- InterPro:   IPR002661
- InterPro:   IPR015998
- PANTHER:   PTHR20982
- PANTHER:   PTHR20982:SF3
- TIGRFAMs:   TIGR00496

Pfam domain/function: PF01765 RRF; SSF55194 Ribosome_recyc_fac

EC number: NA

Molecular weight: Translated: 20476; Mature: 20476

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINEIKKDAKERMTKSVESLAHNFGRIRTGQAHPSILEGVMVPYYGADTPIKQVANITVK
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHCHHC
DARTLQVVAFERNMLGAVDKAIGSAGLNLNPTNLGELLLISMPALTEETRRGFTKQARDV
CCCEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHH
AEDARVAVRNIRRDANSSLKDLVKEKEISEDEERRAAGEIDDLTKKFVAEIDAKLAEKEK
HHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
DLMAV
HHCCC
>Mature Secondary Structure
MINEIKKDAKERMTKSVESLAHNFGRIRTGQAHPSILEGVMVPYYGADTPIKQVANITVK
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHCHHC
DARTLQVVAFERNMLGAVDKAIGSAGLNLNPTNLGELLLISMPALTEETRRGFTKQARDV
CCCEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHH
AEDARVAVRNIRRDANSSLKDLVKEKEISEDEERRAAGEIDDLTKKFVAEIDAKLAEKEK
HHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
DLMAV
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA