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The map label for this gene is cobK [H]

Identifier: 77456829

GI number: 77456829

Start: 693509

End: 694237

Strand: Reverse

Name: cobK [H]

Synonym: Pfl01_0601

Alternate gene names: 77456829

Gene position: 694237-693509 (Counterclockwise)

Preceding gene: 77456830

Following gene: 77456828

Centisome position: 10.78

GC content: 66.8

Gene sequence:

>729_bases
ATGAAGCGAATCTTGTTGCTGGGCGGTGTGACTGAAGCGCTGGCCATCGCGCGCACGTTGGGGCCGGAACACATTTACAG
CCTGGCCGGCGTCGGCCGGGTGCCGACCGATCTGACCTGTCAGGTGCGCGTCGGCGGCTACGGTGGCGCCGAAGGTCTGG
CGCAGTTCATTCGCGCTAAAGGCATCACGCTTTTACTCGACGCGACCCATCCCTACGCCGCACAGATCAGCCAGAACGCC
GCCACCGCCGCGCAACTCACCGGCATCCCCTGCTGGGCCCTGCGCCGCCCGGCCTGGCAACCGCAACCGGGCGATGACTG
GCGCGAAGTCGCCGACTGGGCCGAACTGATCACCGCCCTCGAACCCTTCCGCCGCCCCCTGTTCACCCTCGGCCGCGAAC
CGCTGCAACACCTCGATGAAATCCCCGCGCACCAGTTCTGGACCCTGCGCGCCCTCGACGTCTACCCCGGCAACGAACGC
TGCGAAGTCATCGGCGCCCGTGGACCGTTTCTGCTGGAGGACGAGCGAGCGCTGTTCGAACGCCGGCAGATCGACGTGCT
GATCAGCAAGAACAGCGGCAGCACCGCAACCGAGCCCAAGCTGGAAGTGGCGCGAGAGCTTGGGGTGCCGGTGATGGTGT
TGAAGCGGCCGGAGTTGGCGAGGGTTGATCGGGAGTTTTGGACGGTTGCTGACGCCATCGCTGCCCTCGCGGCCGGAGTC
CGACCGTGA

Upstream 100 bases:

>100_bases
CTCTGGAGTTCGCACGCAGCGTGGTACCGGCGCAGGTCCAGGTCGAAGTGTTTGCGATAGATCGTCAGGGCGGCATCGTC
GGCCATGCGGGAGCCTTTGT

Downstream 100 bases:

>100_bases
AAAACAAAAAGCTCAAGTCCTACTGAGTGCTAGGACACTGCCCACAAGAACTTAAAGAATCGCTGACTATCTGCACGAGC
GGCCCAGGCTTACGTTTAGC

Product: cobalt-precorrin-6x reductase

Products: NA

Alternate protein names: Precorrin-6X reductase [H]

Number of amino acids: Translated: 242; Mature: 242

Protein sequence:

>242_residues
MKRILLLGGVTEALAIARTLGPEHIYSLAGVGRVPTDLTCQVRVGGYGGAEGLAQFIRAKGITLLLDATHPYAAQISQNA
ATAAQLTGIPCWALRRPAWQPQPGDDWREVADWAELITALEPFRRPLFTLGREPLQHLDEIPAHQFWTLRALDVYPGNER
CEVIGARGPFLLEDERALFERRQIDVLISKNSGSTATEPKLEVARELGVPVMVLKRPELARVDREFWTVADAIAALAAGV
RP

Sequences:

>Translated_242_residues
MKRILLLGGVTEALAIARTLGPEHIYSLAGVGRVPTDLTCQVRVGGYGGAEGLAQFIRAKGITLLLDATHPYAAQISQNA
ATAAQLTGIPCWALRRPAWQPQPGDDWREVADWAELITALEPFRRPLFTLGREPLQHLDEIPAHQFWTLRALDVYPGNER
CEVIGARGPFLLEDERALFERRQIDVLISKNSGSTATEPKLEVARELGVPVMVLKRPELARVDREFWTVADAIAALAAGV
RP
>Mature_242_residues
MKRILLLGGVTEALAIARTLGPEHIYSLAGVGRVPTDLTCQVRVGGYGGAEGLAQFIRAKGITLLLDATHPYAAQISQNA
ATAAQLTGIPCWALRRPAWQPQPGDDWREVADWAELITALEPFRRPLFTLGREPLQHLDEIPAHQFWTLRALDVYPGNER
CEVIGARGPFLLEDERALFERRQIDVLISKNSGSTATEPKLEVARELGVPVMVLKRPELARVDREFWTVADAIAALAAGV
RP

Specific function: Catalyzes the reduction of the macrocycle of precorrin- 6X into precorrin-6Y [H]

COG id: COG2099

COG function: function code H; Precorrin-6x reductase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin-6x reductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003723 [H]

Pfam domain/function: PF02571 CbiJ [H]

EC number: =1.3.1.54 [H]

Molecular weight: Translated: 26599; Mature: 26599

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00304 SASP_1 ; PS51014 COBK_CBIJ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRILLLGGVTEALAIARTLGPEHIYSLAGVGRVPTDLTCQVRVGGYGGAEGLAQFIRAK
CCEEEEECCHHHHHHHHHHCCHHHHHHHHCCCCCCCCCEEEEEECCCCCHHHHHHHHHHC
GITLLLDATHPYAAQISQNAATAAQLTGIPCWALRRPAWQPQPGDDWREVADWAELITAL
CCEEEEECCCCHHHHHHHCHHHHHHHCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
EPFRRPLFTLGREPLQHLDEIPAHQFWTLRALDVYPGNERCEVIGARGPFLLEDERALFE
HHHHHHHHHHCHHHHHHHHHCCCCCEEEEEEEEECCCCCCEEEEECCCCEEECHHHHHHH
RRQIDVLISKNSGSTATEPKLEVARELGVPVMVLKRPELARVDREFWTVADAIAALAAGV
HHCEEEEEECCCCCCCCCHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHCC
RP
CC
>Mature Secondary Structure
MKRILLLGGVTEALAIARTLGPEHIYSLAGVGRVPTDLTCQVRVGGYGGAEGLAQFIRAK
CCEEEEECCHHHHHHHHHHCCHHHHHHHHCCCCCCCCCEEEEEECCCCCHHHHHHHHHHC
GITLLLDATHPYAAQISQNAATAAQLTGIPCWALRRPAWQPQPGDDWREVADWAELITAL
CCEEEEECCCCHHHHHHHCHHHHHHHCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
EPFRRPLFTLGREPLQHLDEIPAHQFWTLRALDVYPGNERCEVIGARGPFLLEDERALFE
HHHHHHHHHHCHHHHHHHHHCCCCCEEEEEEEEECCCCCCEEEEECCCCEEECHHHHHHH
RRQIDVLISKNSGSTATEPKLEVARELGVPVMVLKRPELARVDREFWTVADAIAALAAGV
HHCEEEEEECCCCCCCCCHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHCC
RP
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2211521; 1732193 [H]