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The map label for this gene is dsbC [H]

Identifier: 73542719

GI number: 73542719

Start: 3339641

End: 3340390

Strand: Reverse

Name: dsbC [H]

Synonym: Reut_A3035

Alternate gene names: 73542719

Gene position: 3340390-3339641 (Counterclockwise)

Preceding gene: 73542720

Following gene: 73542718

Centisome position: 87.75

GC content: 65.07

Gene sequence:

>750_bases
ATGTTCCAACTCATGCGCCGCCACCCTGCCTGGACCACTGCCATTGCCGGCGGTCTGGCGGCCGCAGGCTTTGCCCTGCA
CGCCATGGCGGCGGGCGAACCGGGCACGGACCGCATCAAGGAATCCCTGCAGAAGATGCTGGGCGGCCGCGCCGAAGTGA
AGAGCGTGACCAAGAGCCCGGTGCCGGGCCTGTTCGAGGTCAATGTCGGCGGGCAGGTGGTCTACACCGATGCCACCGGC
CGCTACGTGATCAACGGCGAGATGATCGATACCAAGACCGGCACCAACCTGACGGAAGAGCGCCTGGCCGACATCAACCG
CATCAAGTGGTCCGACCTGCCGCTCGCGCGCGCCATCAAATGGACCAAGGGAGACGGCAGCCGCCAGGTCGCCGTGTTCT
CCGATCCGAACTGCGGCTACTGCAAGCGCATCGAGCAGACCTTCCAGCAGATGGACAACATCACGGTCTACACCTTCCTG
TATCCGGTGCTGTCGCCCGATTCGGAAACCAAGGCGAAGCAGGTCTGGTGCTCCGCCGACCGCACCAAGGCGTGGCGCGA
CTGGATGCTGAACAAGGTCGCGCTGACCGGCAACGGCAACTGCAAGACGCCGCTCGACGACAACCTCGCACTCGGCCAGC
GCATGAACATCACGGGCACGCCCGCGGTGTTCTTCATGGACGGCACGCGCATTCCGGGCGCGGCCGACGCCGGCACGCTC
GAACGCAAGCTCGCCAGCATCAAGAAGTAA

Upstream 100 bases:

>100_bases
CGCACCGTAGGGCGGCAGTCGCTGCTCAAGCGCATCCTGATTGAACGGGCGCTCGGCTGACGCCGGGTGCCCGGACCTTG
ACTGAATACCTGGAGTCGAT

Downstream 100 bases:

>100_bases
GGATCGGCCGGCAATGTCCCGGCCCGAGCAGGCGGCCGGCTCAGTCCGGCCGTTTTGCTTTGCGGACCATCCCCGCATCA
TCCCTTCGCAAGATCGCCCG

Product: thiol:disulfide interchange protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 249; Mature: 249

Protein sequence:

>249_residues
MFQLMRRHPAWTTAIAGGLAAAGFALHAMAAGEPGTDRIKESLQKMLGGRAEVKSVTKSPVPGLFEVNVGGQVVYTDATG
RYVINGEMIDTKTGTNLTEERLADINRIKWSDLPLARAIKWTKGDGSRQVAVFSDPNCGYCKRIEQTFQQMDNITVYTFL
YPVLSPDSETKAKQVWCSADRTKAWRDWMLNKVALTGNGNCKTPLDDNLALGQRMNITGTPAVFFMDGTRIPGAADAGTL
ERKLASIKK

Sequences:

>Translated_249_residues
MFQLMRRHPAWTTAIAGGLAAAGFALHAMAAGEPGTDRIKESLQKMLGGRAEVKSVTKSPVPGLFEVNVGGQVVYTDATG
RYVINGEMIDTKTGTNLTEERLADINRIKWSDLPLARAIKWTKGDGSRQVAVFSDPNCGYCKRIEQTFQQMDNITVYTFL
YPVLSPDSETKAKQVWCSADRTKAWRDWMLNKVALTGNGNCKTPLDDNLALGQRMNITGTPAVFFMDGTRIPGAADAGTL
ERKLASIKK
>Mature_249_residues
MFQLMRRHPAWTTAIAGGLAAAGFALHAMAAGEPGTDRIKESLQKMLGGRAEVKSVTKSPVPGLFEVNVGGQVVYTDATG
RYVINGEMIDTKTGTNLTEERLADINRIKWSDLPLARAIKWTKGDGSRQVAVFSDPNCGYCKRIEQTFQQMDNITVYTFL
YPVLSPDSETKAKQVWCSADRTKAWRDWMLNKVALTGNGNCKTPLDDNLALGQRMNITGTPAVFFMDGTRIPGAADAGTL
ERKLASIKK

Specific function: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process [H]

COG id: COG1651

COG function: function code O; Protein-disulfide isomerase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioredoxin family. DsbC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789260, Length=220, Percent_Identity=28.1818181818182, Blast_Score=91, Evalue=7e-20,

Paralogues:

None

Copy number: 100 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018950
- InterPro:   IPR009094
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10411 DsbC_N [H]

EC number: 5.3.4.1

Molecular weight: Translated: 27263; Mature: 27263

Theoretical pI: Translated: 9.63; Mature: 9.63

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFQLMRRHPAWTTAIAGGLAAAGFALHAMAAGEPGTDRIKESLQKMLGGRAEVKSVTKSP
CCCCHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHCCC
VPGLFEVNVGGQVVYTDATGRYVINGEMIDTKTGTNLTEERLADINRIKWSDLPLARAIK
CCCEEEEECCCEEEEECCCCCEEEECEEEECCCCCCHHHHHHHHHHHCCCCCCCHHHHEE
WTKGDGSRQVAVFSDPNCGYCKRIEQTFQQMDNITVYTFLYPVLSPDSETKAKQVWCSAD
ECCCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCEEEEEEEECCCCCCCHHHHHHHHCCC
RTKAWRDWMLNKVALTGNGNCKTPLDDNLALGQRMNITGTPAVFFMDGTRIPGAADAGTL
CHHHHHHHHHEEEEEECCCCCCCCCCCCCCCCCEECCCCCCEEEEEECCCCCCCCCCHHH
ERKLASIKK
HHHHHHHCC
>Mature Secondary Structure
MFQLMRRHPAWTTAIAGGLAAAGFALHAMAAGEPGTDRIKESLQKMLGGRAEVKSVTKSP
CCCCHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHCCC
VPGLFEVNVGGQVVYTDATGRYVINGEMIDTKTGTNLTEERLADINRIKWSDLPLARAIK
CCCEEEEECCCEEEEECCCCCEEEECEEEECCCCCCHHHHHHHHHHHCCCCCCCHHHHEE
WTKGDGSRQVAVFSDPNCGYCKRIEQTFQQMDNITVYTFLYPVLSPDSETKAKQVWCSAD
ECCCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCEEEEEEEECCCCCCCHHHHHHHHCCC
RTKAWRDWMLNKVALTGNGNCKTPLDDNLALGQRMNITGTPAVFFMDGTRIPGAADAGTL
CHHHHHHHHHEEEEEECCCCCCCCCCCCCCCCCEECCCCCCEEEEEECCCCCCCCCCHHH
ERKLASIKK
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12910271 [H]