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The map label for this gene is yggV [C]

Identifier: 73542164

GI number: 73542164

Start: 2718223

End: 2718840

Strand: Direct

Name: yggV [C]

Synonym: Reut_A2478

Alternate gene names: 73542164

Gene position: 2718223-2718840 (Clockwise)

Preceding gene: 161611257

Following gene: 73542165

Centisome position: 71.41

GC content: 67.96

Gene sequence:

>618_bases
ATGCAACGCCTGGTTCTGGCCTCCAACAATGCCGGCAAGCTGCGCGAATTCGGCGCGCTGCTGGCCCCGCTCGGCTTTGA
CGTAGTGCCGCAGGGTGAACTCGGCGTCCCGGAAGCCGAAGAGCCCTTCGCCACCTTCGTCGAGAACGCACTGGCCAAGG
CCCGGCACGCGAGCCTGCTGGCAGGCATGCCGGCACTTGCGGACGACTCCGGCATCTGCGTGCAGGCACTGGACGGTGCG
CCCGGCGTCTACTCCGCGCGCTACGCGCAGATGGCCGGCAAGTCCAAGTCCGACCAGGCCAACAATCTGCACCTGATCTC
GCAGCTCGCCGGCAAGCTGAACCGCCGCGCGCACTACTACTGCGTGCTGGTGTTCGTGCGCCATGCCGCCGATCCGTGCC
CGATCATCGCCGAAGGCCTATGGCATGGCGAAGTCGTCGATGCGCCGCGCGGTGCGGGCGGCTTCGGCTACGACCCGCAC
TTCATGTTGCCGGACCTCGGCAAGACCGCAGCAGAGCTGCCGGCCGAAGAAAAGAACGCTGTCAGCCATCGCGCGCTCGC
GCTGCGTTCGCTGGTAGCGCGCCTGCAGGCCGAAGGCCGCGGCAAGGCCACGCGATGA

Upstream 100 bases:

>100_bases
CGATCTGGACGCCATGACGCGCCTGGCCGAAGACGGCATCGCGCAACTGGTCCGCCACCAGCGCCAGGCGCTGGGCCTGG
CCTGAAGGACGGAAGTCGCC

Downstream 100 bases:

>100_bases
TCCCGATCGTACCGGCCGGCGCCGCGCCGGCCACCACGCCCGACAACACGCAGCTCTGGCTCAAGCCCGGTCAGATCGCA
CTACCGGGCTCGCCGCCACT

Product: putative deoxyribonucleotide triphosphate pyrophosphatase

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase [H]

Number of amino acids: Translated: 205; Mature: 205

Protein sequence:

>205_residues
MQRLVLASNNAGKLREFGALLAPLGFDVVPQGELGVPEAEEPFATFVENALAKARHASLLAGMPALADDSGICVQALDGA
PGVYSARYAQMAGKSKSDQANNLHLISQLAGKLNRRAHYYCVLVFVRHAADPCPIIAEGLWHGEVVDAPRGAGGFGYDPH
FMLPDLGKTAAELPAEEKNAVSHRALALRSLVARLQAEGRGKATR

Sequences:

>Translated_205_residues
MQRLVLASNNAGKLREFGALLAPLGFDVVPQGELGVPEAEEPFATFVENALAKARHASLLAGMPALADDSGICVQALDGA
PGVYSARYAQMAGKSKSDQANNLHLISQLAGKLNRRAHYYCVLVFVRHAADPCPIIAEGLWHGEVVDAPRGAGGFGYDPH
FMLPDLGKTAAELPAEEKNAVSHRALALRSLVARLQAEGRGKATR
>Mature_205_residues
MQRLVLASNNAGKLREFGALLAPLGFDVVPQGELGVPEAEEPFATFVENALAKARHASLLAGMPALADDSGICVQALDGA
PGVYSARYAQMAGKSKSDQANNLHLISQLAGKLNRRAHYYCVLVFVRHAADPCPIIAEGLWHGEVVDAPRGAGGFGYDPH
FMLPDLGKTAAELPAEEKNAVSHRALALRSLVARLQAEGRGKATR

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions [H]

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family [H]

Homologues:

Organism=Homo sapiens, GI15626999, Length=193, Percent_Identity=32.1243523316062, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI31657144, Length=146, Percent_Identity=35.6164383561644, Blast_Score=67, Evalue=9e-12,
Organism=Escherichia coli, GI1789324, Length=198, Percent_Identity=50, Blast_Score=201, Evalue=4e-53,
Organism=Caenorhabditis elegans, GI17556833, Length=199, Percent_Identity=29.6482412060301, Blast_Score=71, Evalue=3e-13,
Organism=Drosophila melanogaster, GI19920712, Length=197, Percent_Identity=30.9644670050761, Blast_Score=89, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002637
- InterPro:   IPR020922 [H]

Pfam domain/function: PF01725 Ham1p_like [H]

EC number: =3.6.1.15 [H]

Molecular weight: Translated: 21732; Mature: 21732

Theoretical pI: Translated: 7.64; Mature: 7.64

Prosite motif: PS50096 IQ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRLVLASNNAGKLREFGALLAPLGFDVVPQGELGVPEAEEPFATFVENALAKARHASLL
CCEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
AGMPALADDSGICVQALDGAPGVYSARYAQMAGKSKSDQANNLHLISQLAGKLNRRAHYY
HCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCHHHH
CVLVFVRHAADPCPIIAEGLWHGEVVDAPRGAGGFGYDPHFMLPDLGKTAAELPAEEKNA
HHHHHHHHCCCCCCHHHHCCCCCCEECCCCCCCCCCCCCCCCCCCCCCHHHHCCCHHHHH
VSHRALALRSLVARLQAEGRGKATR
HHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MQRLVLASNNAGKLREFGALLAPLGFDVVPQGELGVPEAEEPFATFVENALAKARHASLL
CCEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
AGMPALADDSGICVQALDGAPGVYSARYAQMAGKSKSDQANNLHLISQLAGKLNRRAHYY
HCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCHHHH
CVLVFVRHAADPCPIIAEGLWHGEVVDAPRGAGGFGYDPHFMLPDLGKTAAELPAEEKNA
HHHHHHHHCCCCCCHHHHCCCCCCEECCCCCCCCCCCCCCCCCCCCCCHHHHCCCHHHHH
VSHRALALRSLVARLQAEGRGKATR
HHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]