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The map label for this gene is yggW [H]

Identifier: 73542165

GI number: 73542165

Start: 2718837

End: 2720078

Strand: Direct

Name: yggW [H]

Synonym: Reut_A2479

Alternate gene names: 73542165

Gene position: 2718837-2720078 (Clockwise)

Preceding gene: 73542164

Following gene: 73542168

Centisome position: 71.43

GC content: 64.98

Gene sequence:

>1242_bases
ATGATCCCGATCGTACCGGCCGGCGCCGCGCCGGCCACCACGCCCGACAACACGCAGCTCTGGCTCAAGCCCGGTCAGAT
CGCACTACCGGGCTCGCCGCCACTGTCGCTCTATGTGCATGTGCCATGGTGCGTGCGCAAGTGCCCGTACTGCGATTTCA
ATTCGCATGCCGTGCCGGGCAAGGACGGCAGCCACGACATTCCGGAAGACGCTTACCTCGACGCGTTACGTGCGGACCTG
GAGCAGTCGCTGCCGCTGGTCTGGGGCCGTCCGGTCCATACCGTGTTTATCGGCGGCGGCACACCGAGTCTGCTGTCTGC
AGCTGGCATGGACCGGCTGCTGTCGGATATCCGGGCATTGCTGCCGCTCGATGCCGATGCCGAGATCACGATGGAGGCCA
ACCCCGGCACCTTCGAAGCCGAGCGTTTCGCGAGCTATCGCGCGAGCGGTGTGAACCGGCTTTCCATCGGCATCCAGAGT
TTCAACGACAGCCACCTGCAGGCGCTCGGCCGTATCCATGGCGAACGCGAGGCACGAGCGGCCATCGATATCGCGCAACG
CAGCTTCGACAACGTCAACCTTGACCTGATGTACGCGCTGCCCGGCCAGACGCTGGAACAGTGCCGCAGCGACCTGGAAA
GCGCGTTGTCGTATGGCACCACACACCTGTCGCTCTACCACCTGACGCTCGAGCCAAACACGCTGTTCGCGAAGTTCCCG
CCCGCGCTGCCAGACGATGACCTCGCCTACGAGATGCAGGACCTGATCGAGGCCCGCACCACAGAAGCCGGCTACCGGCA
CTACGAGACCTCGGCCTATGCACGCGCGCATCGCGAGGCGCGGCACAACCTGAACTACTGGCGCTTCGGCGACTACCTTG
GGATCGGCGCCGGCGCGCACGGCAAGTTGTCGTTCCCCAACCGCATCCTGCGCCAGATGCGGCACAAGCACCCTGCCACC
TACATGGCGCAGGCGATGGCCGGCAATGCGGTGCAGGAAGCGCGCGAAGTCGGCGCGGACGAACTGCCGTTCGAGTTCAT
GCTTAACGCACTGCGCCTCACTGATGGCGTGCCGGCCTCCAGCTTCCACGACATGACCGGCCTGCCGCTGCATGCGATCA
GCCGGCAGCTCGCGGCGGCGGAGAAGAAGGGATTGCTCGATGCCGATCCGACGGTGATCCGCCCTACCGAACTCGGCCGG
CGCTTCCTCAACGACTTGCAGGAGATGTTCCTGAAGGACTGA

Upstream 100 bases:

>100_bases
AGCTGCCGGCCGAAGAAAAGAACGCTGTCAGCCATCGCGCGCTCGCGCTGCGTTCGCTGGTAGCGCGCCTGCAGGCCGAA
GGCCGCGGCAAGGCCACGCG

Downstream 100 bases:

>100_bases
AGCGTCAAGACAGGGGCACGAAAGCACGAAGGCCACGGCATTGCCGTGGCCTTCGTTGCTTTGTGGACCCGATCCAGGAT
CAGTACGGCACCGCCATGTC

Product: coproporphyrinogen III oxidase

Products: Protoporphyrinogen IX; CO2; H2O

Alternate protein names: NA

Number of amino acids: Translated: 413; Mature: 413

Protein sequence:

>413_residues
MIPIVPAGAAPATTPDNTQLWLKPGQIALPGSPPLSLYVHVPWCVRKCPYCDFNSHAVPGKDGSHDIPEDAYLDALRADL
EQSLPLVWGRPVHTVFIGGGTPSLLSAAGMDRLLSDIRALLPLDADAEITMEANPGTFEAERFASYRASGVNRLSIGIQS
FNDSHLQALGRIHGEREARAAIDIAQRSFDNVNLDLMYALPGQTLEQCRSDLESALSYGTTHLSLYHLTLEPNTLFAKFP
PALPDDDLAYEMQDLIEARTTEAGYRHYETSAYARAHREARHNLNYWRFGDYLGIGAGAHGKLSFPNRILRQMRHKHPAT
YMAQAMAGNAVQEAREVGADELPFEFMLNALRLTDGVPASSFHDMTGLPLHAISRQLAAAEKKGLLDADPTVIRPTELGR
RFLNDLQEMFLKD

Sequences:

>Translated_413_residues
MIPIVPAGAAPATTPDNTQLWLKPGQIALPGSPPLSLYVHVPWCVRKCPYCDFNSHAVPGKDGSHDIPEDAYLDALRADL
EQSLPLVWGRPVHTVFIGGGTPSLLSAAGMDRLLSDIRALLPLDADAEITMEANPGTFEAERFASYRASGVNRLSIGIQS
FNDSHLQALGRIHGEREARAAIDIAQRSFDNVNLDLMYALPGQTLEQCRSDLESALSYGTTHLSLYHLTLEPNTLFAKFP
PALPDDDLAYEMQDLIEARTTEAGYRHYETSAYARAHREARHNLNYWRFGDYLGIGAGAHGKLSFPNRILRQMRHKHPAT
YMAQAMAGNAVQEAREVGADELPFEFMLNALRLTDGVPASSFHDMTGLPLHAISRQLAAAEKKGLLDADPTVIRPTELGR
RFLNDLQEMFLKD
>Mature_413_residues
MIPIVPAGAAPATTPDNTQLWLKPGQIALPGSPPLSLYVHVPWCVRKCPYCDFNSHAVPGKDGSHDIPEDAYLDALRADL
EQSLPLVWGRPVHTVFIGGGTPSLLSAAGMDRLLSDIRALLPLDADAEITMEANPGTFEAERFASYRASGVNRLSIGIQS
FNDSHLQALGRIHGEREARAAIDIAQRSFDNVNLDLMYALPGQTLEQCRSDLESALSYGTTHLSLYHLTLEPNTLFAKFP
PALPDDDLAYEMQDLIEARTTEAGYRHYETSAYARAHREARHNLNYWRFGDYLGIGAGAHGKLSFPNRILRQMRHKHPAT
YMAQAMAGNAVQEAREVGADELPFEFMLNALRLTDGVPASSFHDMTGLPLHAISRQLAAAEKKGLLDADPTVIRPTELGR
RFLNDLQEMFLKD

Specific function: Unknown

COG id: COG0635

COG function: function code H; Coproporphyrinogen III oxidase and related Fe-S oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anaerobic coproporphyrinogen-III oxidase family [H]

Homologues:

Organism=Homo sapiens, GI8922911, Length=274, Percent_Identity=40.8759124087591, Blast_Score=182, Evalue=6e-46,
Organism=Escherichia coli, GI1789325, Length=386, Percent_Identity=51.0362694300518, Blast_Score=378, Evalue=1e-106,
Organism=Escherichia coli, GI87082341, Length=399, Percent_Identity=29.3233082706767, Blast_Score=133, Evalue=3e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR004559
- InterPro:   IPR010723
- InterPro:   IPR007197 [H]

Pfam domain/function: PF06969 HemN_C; PF04055 Radical_SAM [H]

EC number: 1.3.3.3

Molecular weight: Translated: 45548; Mature: 45548

Theoretical pI: Translated: 5.82; Mature: 5.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPIVPAGAAPATTPDNTQLWLKPGQIALPGSPPLSLYVHVPWCVRKCPYCDFNSHAVPG
CCCCCCCCCCCCCCCCCCEEEEECCCEECCCCCCEEEEEECCHHHHHCCCCCCCCCCCCC
KDGSHDIPEDAYLDALRADLEQSLPLVWGRPVHTVFIGGGTPSLLSAAGMDRLLSDIRAL
CCCCCCCCHHHHHHHHHHHHHHCCCEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHHHH
LPLDADAEITMEANPGTFEAERFASYRASGVNRLSIGIQSFNDSHLQALGRIHGEREARA
CCCCCCCEEEEECCCCCCHHHHHHHHHHCCCCEEEEEHHCCCHHHHHHHHHHCCHHHHHH
AIDIAQRSFDNVNLDLMYALPGQTLEQCRSDLESALSYGTTHLSLYHLTLEPNTLFAKFP
HHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHCCCEEEEEEEEEECCCEEEEECC
PALPDDDLAYEMQDLIEARTTEAGYRHYETSAYARAHREARHNLNYWRFGDYLGIGAGAH
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCEEEECCCCC
GKLSFPNRILRQMRHKHPATYMAQAMAGNAVQEAREVGADELPFEFMLNALRLTDGVPAS
CCCCCHHHHHHHHHHCCCHHHHHHHHHCHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCC
SFHDMTGLPLHAISRQLAAAEKKGLLDADPTVIRPTELGRRFLNDLQEMFLKD
CCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEECHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIPIVPAGAAPATTPDNTQLWLKPGQIALPGSPPLSLYVHVPWCVRKCPYCDFNSHAVPG
CCCCCCCCCCCCCCCCCCEEEEECCCEECCCCCCEEEEEECCHHHHHCCCCCCCCCCCCC
KDGSHDIPEDAYLDALRADLEQSLPLVWGRPVHTVFIGGGTPSLLSAAGMDRLLSDIRAL
CCCCCCCCHHHHHHHHHHHHHHCCCEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHHHH
LPLDADAEITMEANPGTFEAERFASYRASGVNRLSIGIQSFNDSHLQALGRIHGEREARA
CCCCCCCEEEEECCCCCCHHHHHHHHHHCCCCEEEEEHHCCCHHHHHHHHHHCCHHHHHH
AIDIAQRSFDNVNLDLMYALPGQTLEQCRSDLESALSYGTTHLSLYHLTLEPNTLFAKFP
HHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHCCCEEEEEEEEEECCCEEEEECC
PALPDDDLAYEMQDLIEARTTEAGYRHYETSAYARAHREARHNLNYWRFGDYLGIGAGAH
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCEEEECCCCC
GKLSFPNRILRQMRHKHPATYMAQAMAGNAVQEAREVGADELPFEFMLNALRLTDGVPAS
CCCCCHHHHHHHHHHCCCHHHHHHHHHCHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCC
SFHDMTGLPLHAISRQLAAAEKKGLLDADPTVIRPTELGRRFLNDLQEMFLKD
CCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEECHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Coproporphyrinogen III; O2; H+

Specific reaction: coproporphyrinogen-III + O2 + 2 H+ = protoporphyrinogen-IX + 2 CO2 + 2 H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]