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The map label for this gene is yfbQ [H]

Identifier: 73541682

GI number: 73541682

Start: 2184973

End: 2186256

Strand: Reverse

Name: yfbQ [H]

Synonym: Reut_A1994

Alternate gene names: 73541682

Gene position: 2186256-2184973 (Counterclockwise)

Preceding gene: 73541688

Following gene: 73541681

Centisome position: 57.43

GC content: 61.29

Gene sequence:

>1284_bases
ATGTTCGCTGCCGCCGACGCGGCAGTTTTCGCCTCCGCCGATATCGCCGTGAAACCCATCCAGAAATCCAACAAACTCAA
TAACGTTTGCTACGACATCCGCGGCCCGGTGCTGGAAAAGGCCAAGCAGATGGAGGAAGAGGGGCACAAGATCATCAAGC
TGAATATCGGCAACCTGGCCGTATTCGGTTTCGATGCCCCGGAGGAAATCCAGCAGGACATGATGCGCAACCTGCCGAAT
TCGGCGGGCTATTCGGATTCCAAGGGCATTTTCGCCGCGCGCAAGGCGATCATGCATTACACGCAGCAGAAAAATATCCA
GGGCGTCGGCCTGGAAGACATCTACGTGGGCAATGGCGCCTCGGAACTGATCGTGATGGCGGTCAACGCGCTGCTCAACA
GCGGCGACGAGGTTCTGGTGCCGGCGCCGGACTATCCGCTGTGGACTGCGGCAGTGAGCCTGTCGGGTGGCACGCCGGTG
CACTATATCTGCGACGAGTCCAACGAGTGGATGCCTGATCCGGCCGATATCCGTGCCCGCATCACGCCGCACACCAAGGC
CATCGTCATCATCAACCCGAACAACCCGACCGGCGCGCTGTATTCGGACGAACTGCTGCTCGAGATCGTCGCGATCGCGC
GCGAGCACGGGCTGATCATCTTCGCCGACGAGATCTACGACAAGGTCCTGTACGACGGCAATGTCCACACCTCAATCGCC
TCGCTGTCGACCGACGTGCTGACGGTGACCTTCAACGGCCTGTCCAAGAACTACCGCTCGTGCGGCTACCGTGCCGGATG
GATGGTGGTGTCGGGCGACAAGCGTCCGGCGCTCGACTATATCGAGGGCCTGAACATGCTGTCCTCGATGCGTCTGTGCG
CGAACGTGCCGGGGCAGTGGGCCATCCAGACCGCGCTGGGCGGCTACCAGAGCATCAACGACCTGGTTGCCGAAGGCGGC
CGCCTGCGTCGCCAACGCGACCTGGCCTATGAGCTGATCACCGCGATTCCGGGCGTGAGCTGCGTCAAGCCCAAGGCCGC
GCTGTACCTGTTCCCGAAGCTGGACCTGTCGATGTACCCGGTGCAGGACGACCAGGAGTTCATTTACGAACTGCTGCAGG
AGTCCAAGGTGCTGCTGGTACAGGGCTCCGGCTTCAACTGGGACAAGCCGGACCACTTCCGAATCGTATTCCTGCCGCAT
GAGGAGGATCTGCGCGAGGCGATCAATCGCATTGCGCGCTTCCTGGAGGCGTATCGAAAACGCCACGGCAAGGTGGCTGC
CTGA

Upstream 100 bases:

>100_bases
CGATAAATTATAGCTTTTGCCTCCGTGTCTGCCACTTTCGCGGCGTGACTGCGTTGCATCGCAGCGGACGGCGCCCCCGA
GACACTCCATCCGGATTCCC

Downstream 100 bases:

>100_bases
TCAGGTGGCCGCTGCAACTTATCCTTAGCAACCTAGAGTCAGATCGTCCATGAACCCCATCAAAGTTGGCCTGCTCGGCA
TCGGTACCGTCGGTAGCGGC

Product: aminotransferase AlaT

Products: oxaloacetate; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 427; Mature: 427

Protein sequence:

>427_residues
MFAAADAAVFASADIAVKPIQKSNKLNNVCYDIRGPVLEKAKQMEEEGHKIIKLNIGNLAVFGFDAPEEIQQDMMRNLPN
SAGYSDSKGIFAARKAIMHYTQQKNIQGVGLEDIYVGNGASELIVMAVNALLNSGDEVLVPAPDYPLWTAAVSLSGGTPV
HYICDESNEWMPDPADIRARITPHTKAIVIINPNNPTGALYSDELLLEIVAIAREHGLIIFADEIYDKVLYDGNVHTSIA
SLSTDVLTVTFNGLSKNYRSCGYRAGWMVVSGDKRPALDYIEGLNMLSSMRLCANVPGQWAIQTALGGYQSINDLVAEGG
RLRRQRDLAYELITAIPGVSCVKPKAALYLFPKLDLSMYPVQDDQEFIYELLQESKVLLVQGSGFNWDKPDHFRIVFLPH
EEDLREAINRIARFLEAYRKRHGKVAA

Sequences:

>Translated_427_residues
MFAAADAAVFASADIAVKPIQKSNKLNNVCYDIRGPVLEKAKQMEEEGHKIIKLNIGNLAVFGFDAPEEIQQDMMRNLPN
SAGYSDSKGIFAARKAIMHYTQQKNIQGVGLEDIYVGNGASELIVMAVNALLNSGDEVLVPAPDYPLWTAAVSLSGGTPV
HYICDESNEWMPDPADIRARITPHTKAIVIINPNNPTGALYSDELLLEIVAIAREHGLIIFADEIYDKVLYDGNVHTSIA
SLSTDVLTVTFNGLSKNYRSCGYRAGWMVVSGDKRPALDYIEGLNMLSSMRLCANVPGQWAIQTALGGYQSINDLVAEGG
RLRRQRDLAYELITAIPGVSCVKPKAALYLFPKLDLSMYPVQDDQEFIYELLQESKVLLVQGSGFNWDKPDHFRIVFLPH
EEDLREAINRIARFLEAYRKRHGKVAA
>Mature_427_residues
MFAAADAAVFASADIAVKPIQKSNKLNNVCYDIRGPVLEKAKQMEEEGHKIIKLNIGNLAVFGFDAPEEIQQDMMRNLPN
SAGYSDSKGIFAARKAIMHYTQQKNIQGVGLEDIYVGNGASELIVMAVNALLNSGDEVLVPAPDYPLWTAAVSLSGGTPV
HYICDESNEWMPDPADIRARITPHTKAIVIINPNNPTGALYSDELLLEIVAIAREHGLIIFADEIYDKVLYDGNVHTSIA
SLSTDVLTVTFNGLSKNYRSCGYRAGWMVVSGDKRPALDYIEGLNMLSSMRLCANVPGQWAIQTALGGYQSINDLVAEGG
RLRRQRDLAYELITAIPGVSCVKPKAALYLFPKLDLSMYPVQDDQEFIYELLQESKVLLVQGSGFNWDKPDHFRIVFLPH
EEDLREAINRIARFLEAYRKRHGKVAA

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI19263340, Length=472, Percent_Identity=28.3898305084746, Blast_Score=152, Evalue=7e-37,
Organism=Homo sapiens, GI215599424, Length=400, Percent_Identity=29.75, Blast_Score=145, Evalue=9e-35,
Organism=Homo sapiens, GI4507369, Length=413, Percent_Identity=28.5714285714286, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI4885351, Length=448, Percent_Identity=26.3392857142857, Blast_Score=135, Evalue=6e-32,
Organism=Homo sapiens, GI95147551, Length=170, Percent_Identity=30, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI169881279, Length=170, Percent_Identity=30, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI56713254, Length=168, Percent_Identity=28.5714285714286, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI56713256, Length=168, Percent_Identity=28.5714285714286, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI169881281, Length=177, Percent_Identity=28.8135593220339, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI187936925, Length=378, Percent_Identity=23.5449735449735, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI14211921, Length=378, Percent_Identity=23.5449735449735, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI1788627, Length=404, Percent_Identity=65.0990099009901, Blast_Score=563, Evalue=1e-162,
Organism=Escherichia coli, GI1788722, Length=377, Percent_Identity=27.5862068965517, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1786816, Length=375, Percent_Identity=25.3333333333333, Blast_Score=95, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17567663, Length=376, Percent_Identity=31.1170212765957, Blast_Score=163, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI71981209, Length=475, Percent_Identity=26.5263157894737, Blast_Score=136, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI71994476, Length=307, Percent_Identity=28.0130293159609, Blast_Score=99, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI71994472, Length=307, Percent_Identity=28.0130293159609, Blast_Score=99, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI71981215, Length=328, Percent_Identity=27.7439024390244, Blast_Score=96, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17567369, Length=210, Percent_Identity=27.6190476190476, Blast_Score=82, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6323118, Length=402, Percent_Identity=28.8557213930348, Blast_Score=148, Evalue=2e-36,
Organism=Saccharomyces cerevisiae, GI6320317, Length=481, Percent_Identity=26.6112266112266, Blast_Score=141, Evalue=3e-34,
Organism=Saccharomyces cerevisiae, GI6322401, Length=350, Percent_Identity=26.2857142857143, Blast_Score=101, Evalue=2e-22,
Organism=Drosophila melanogaster, GI18859735, Length=397, Percent_Identity=28.9672544080605, Blast_Score=167, Evalue=1e-41,
Organism=Drosophila melanogaster, GI24641770, Length=467, Percent_Identity=25.4817987152034, Blast_Score=138, Evalue=8e-33,
Organism=Drosophila melanogaster, GI24641760, Length=467, Percent_Identity=25.4817987152034, Blast_Score=138, Evalue=8e-33,
Organism=Drosophila melanogaster, GI24641768, Length=467, Percent_Identity=25.4817987152034, Blast_Score=138, Evalue=8e-33,
Organism=Drosophila melanogaster, GI24641766, Length=467, Percent_Identity=25.4817987152034, Blast_Score=138, Evalue=8e-33,
Organism=Drosophila melanogaster, GI24641764, Length=467, Percent_Identity=25.4817987152034, Blast_Score=138, Evalue=8e-33,
Organism=Drosophila melanogaster, GI45551451, Length=467, Percent_Identity=25.4817987152034, Blast_Score=137, Evalue=9e-33,
Organism=Drosophila melanogaster, GI28573069, Length=334, Percent_Identity=22.4550898203593, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24646114, Length=334, Percent_Identity=22.4550898203593, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI28573067, Length=334, Percent_Identity=22.4550898203593, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI28573065, Length=334, Percent_Identity=22.4550898203593, Blast_Score=81, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.1

Molecular weight: Translated: 47220; Mature: 47220

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFAAADAAVFASADIAVKPIQKSNKLNNVCYDIRGPVLEKAKQMEEEGHKIIKLNIGNLA
CCCCCCCHHEEECCEEEECCHHCCCCCCCEEECCCHHHHHHHHHHHCCCEEEEEEECCEE
VFGFDAPEEIQQDMMRNLPNSAGYSDSKGIFAARKAIMHYTQQKNIQGVGLEDIYVGNGA
EEECCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEECCCH
SELIVMAVNALLNSGDEVLVPAPDYPLWTAAVSLSGGTPVHYICDESNEWMPDPADIRAR
HHHHHHHHHHHHCCCCEEEEECCCCCEEEEEEEECCCCEEEEEECCCCCCCCCCCCCEEE
ITPHTKAIVIINPNNPTGALYSDELLLEIVAIAREHGLIIFADEIYDKVLYDGNVHTSIA
ECCCCEEEEEEECCCCCCCEEHHHHHHHHHHHHHHCCEEEEEHHHHHHHHCCCCCHHHHH
SLSTDVLTVTFNGLSKNYRSCGYRAGWMVVSGDKRPALDYIEGLNMLSSMRLCANVPGQW
HCCCEEEEEEECCCCCHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCE
AIQTALGGYQSINDLVAEGGRLRRQRDLAYELITAIPGVSCVKPKAALYLFPKLDLSMYP
EHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCEEEC
VQDDQEFIYELLQESKVLLVQGSGFNWDKPDHFRIVFLPHEEDLREAINRIARFLEAYRK
CCCCHHHHHHHHHCCCEEEEECCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHH
RHGKVAA
HCCCCCC
>Mature Secondary Structure
MFAAADAAVFASADIAVKPIQKSNKLNNVCYDIRGPVLEKAKQMEEEGHKIIKLNIGNLA
CCCCCCCHHEEECCEEEECCHHCCCCCCCEEECCCHHHHHHHHHHHCCCEEEEEEECCEE
VFGFDAPEEIQQDMMRNLPNSAGYSDSKGIFAARKAIMHYTQQKNIQGVGLEDIYVGNGA
EEECCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEECCCH
SELIVMAVNALLNSGDEVLVPAPDYPLWTAAVSLSGGTPVHYICDESNEWMPDPADIRAR
HHHHHHHHHHHHCCCCEEEEECCCCCEEEEEEEECCCCEEEEEECCCCCCCCCCCCCEEE
ITPHTKAIVIINPNNPTGALYSDELLLEIVAIAREHGLIIFADEIYDKVLYDGNVHTSIA
ECCCCEEEEEEECCCCCCCEEHHHHHHHHHHHHHHCCEEEEEHHHHHHHHCCCCCHHHHH
SLSTDVLTVTFNGLSKNYRSCGYRAGWMVVSGDKRPALDYIEGLNMLSSMRLCANVPGQW
HCCCEEEEEEECCCCCHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCE
AIQTALGGYQSINDLVAEGGRLRRQRDLAYELITAIPGVSCVKPKAALYLFPKLDLSMYP
EHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCEEEC
VQDDQEFIYELLQESKVLLVQGSGFNWDKPDHFRIVFLPHEEDLREAINRIARFLEAYRK
CCCCHHHHHHHHHCCCEEEEECCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHH
RHGKVAA
HCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-aspartate; 2-oxoglutarate

Specific reaction: L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]