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The map label for this gene is fsr [C]

Identifier: 73541652

GI number: 73541652

Start: 2149864

End: 2151186

Strand: Reverse

Name: fsr [C]

Synonym: Reut_A1964

Alternate gene names: 73541652

Gene position: 2151186-2149864 (Counterclockwise)

Preceding gene: 73541653

Following gene: 73541651

Centisome position: 56.51

GC content: 67.5

Gene sequence:

>1323_bases
ATGCCCTCGCTTGCAGGGCTGCGGCGCGCGTGCCTGGCTCCATCCCGCGAATCCGCCGCCATGACTACCGCCGCTTTCGA
TCCCAGCCGCAATACGCTCCGCCATGATGCCCAGGTGATCGGGCTGGTAGGGCTGGCGCACGGGGTTTCCCACTTCTATC
ACCTGTTGCTGGCGCCGCTGTTCCCATGGATCAAGGCGGAGTTCGGCCTTAGCTATGCCGAGCTCGGGCTGCTGATGACG
GTCTTCTTTGCTGTGTCGGCAGTGGTGCAGACGGCGTCAGGCTTCGTCGTGGATCGCATAGGCGCCCGGCCGGTGCTGTT
TGGCGGTCTGGCCTTCCTGGGTGCGGCGGCCTTGCTGCTGTCGACGAGCACCGGCTATGCGATGCTGCTGTTCGGCGCCG
GCGTGGCGGGACTGGGCAACGGCGTCTTCCATCCGGCCGATTTCACGCTGCTGAACAAGCATGTGTCGCAGCCTCGGCTA
GGCCATGCGTTCTCGGTGCACGGCATCTCGGGCAACCTGGGCTGGGCGGCCGCACCGGTATTCCTGGTAACCATTGCCAA
CCTGGCGACATGGCGCGTGGCGCTGGCCGCTGCTTCGGTGGTGGCCTTCAGCGTGCTGGCGGTGTTGCTGGTGCTGCGCC
ATGTGCTCGACCCGCGCGAACTGGGCAGTGCGGTCGGCCGTCCCAAGGCCGCGCAGTCCGGCGCCGGCGGCAGCCTGCTG
GGTTTCCTGAAACTGCCGCAGGTCTGGGTATGCTGGGCCTTCTTCCTGCTGACCACGTTCTCGGCCGCCGGCATCCAGAG
CTTCGCACCGACGGCGCTGACGCAGCTCTACGGCATTCCGTTTACGCTCGCGACGGCGTCCTACACCATCTACATGCTCT
GCAGCGCGGGCGGCATGGTGGTCGGCGGGTTTGCCGCGACACGCACGAGCAACCATGACAGGCTGATCGCGCTGAGCTTC
ACGGTATCGGGCCTGATGGCCGTGCTGGTGGGCCTGAATGTTGCACCGGGCCTGTTGGTGCCGGTGCTGCTGGGCGTGGT
CGGCTTTGGCGCGGGCACGGCGGGTCCGTCGCGCGACCTGCTCGTGCGTGCTGCGGCCCCGGCCGGGGCTACCGGGCGCG
TGTACGGGGTGGTGTATTCAGGCCTGGATATCGGCCTGGCGAGCGGCCCGCTGTTCTTCGGTGCGCTGATGGACGCGCAC
CTGCCCAACTGGGTGTTCTTCATGATCGGCGGCTTCCAGCTGGTGTCGATCCTGACCGCCGTGACGGTCGGCAACGGCAA
CCGTTCGCGCCGCGATGCTGGTTCGCAGGCAACGGCGGCCTAG

Upstream 100 bases:

>100_bases
AAGCAGATGTAGTTGGCTCCGGCGTTGCGGCGGCGGCTGCACCGGGACGCAGTCGCTTGCGGTTTTCCACTATGATGCGA
GCTTCGGTGCGCGTTTTTGC

Downstream 100 bases:

>100_bases
CGCTGACCAGGCGGTACCGAAATTCTTCCTTGCAGGAGTGTTAGATGAAGCATGTCACCACCGATCTTTGCGATGCCAAC
GAGCCGCGTCTGGCTGACGG

Product: major facilitator transporter

Products: fosmidomycin [Periplasm]; Proton [Cytoplasm] [C]

Alternate protein names: Facilitator Superfamily Transporter; Facilitator Superfamily Protein; Fosmidomycin Resistance Protein; Multi Drug Efflux Transporter; Facilitator Superfamily Permease

Number of amino acids: Translated: 440; Mature: 439

Protein sequence:

>440_residues
MPSLAGLRRACLAPSRESAAMTTAAFDPSRNTLRHDAQVIGLVGLAHGVSHFYHLLLAPLFPWIKAEFGLSYAELGLLMT
VFFAVSAVVQTASGFVVDRIGARPVLFGGLAFLGAAALLLSTSTGYAMLLFGAGVAGLGNGVFHPADFTLLNKHVSQPRL
GHAFSVHGISGNLGWAAAPVFLVTIANLATWRVALAAASVVAFSVLAVLLVLRHVLDPRELGSAVGRPKAAQSGAGGSLL
GFLKLPQVWVCWAFFLLTTFSAAGIQSFAPTALTQLYGIPFTLATASYTIYMLCSAGGMVVGGFAATRTSNHDRLIALSF
TVSGLMAVLVGLNVAPGLLVPVLLGVVGFGAGTAGPSRDLLVRAAAPAGATGRVYGVVYSGLDIGLASGPLFFGALMDAH
LPNWVFFMIGGFQLVSILTAVTVGNGNRSRRDAGSQATAA

Sequences:

>Translated_440_residues
MPSLAGLRRACLAPSRESAAMTTAAFDPSRNTLRHDAQVIGLVGLAHGVSHFYHLLLAPLFPWIKAEFGLSYAELGLLMT
VFFAVSAVVQTASGFVVDRIGARPVLFGGLAFLGAAALLLSTSTGYAMLLFGAGVAGLGNGVFHPADFTLLNKHVSQPRL
GHAFSVHGISGNLGWAAAPVFLVTIANLATWRVALAAASVVAFSVLAVLLVLRHVLDPRELGSAVGRPKAAQSGAGGSLL
GFLKLPQVWVCWAFFLLTTFSAAGIQSFAPTALTQLYGIPFTLATASYTIYMLCSAGGMVVGGFAATRTSNHDRLIALSF
TVSGLMAVLVGLNVAPGLLVPVLLGVVGFGAGTAGPSRDLLVRAAAPAGATGRVYGVVYSGLDIGLASGPLFFGALMDAH
LPNWVFFMIGGFQLVSILTAVTVGNGNRSRRDAGSQATAA
>Mature_439_residues
PSLAGLRRACLAPSRESAAMTTAAFDPSRNTLRHDAQVIGLVGLAHGVSHFYHLLLAPLFPWIKAEFGLSYAELGLLMTV
FFAVSAVVQTASGFVVDRIGARPVLFGGLAFLGAAALLLSTSTGYAMLLFGAGVAGLGNGVFHPADFTLLNKHVSQPRLG
HAFSVHGISGNLGWAAAPVFLVTIANLATWRVALAAASVVAFSVLAVLLVLRHVLDPRELGSAVGRPKAAQSGAGGSLLG
FLKLPQVWVCWAFFLLTTFSAAGIQSFAPTALTQLYGIPFTLATASYTIYMLCSAGGMVVGGFAATRTSNHDRLIALSFT
VSGLMAVLVGLNVAPGLLVPVLLGVVGFGAGTAGPSRDLLVRAAAPAGATGRVYGVVYSGLDIGLASGPLFFGALMDAHL
PNWVFFMIGGFQLVSILTAVTVGNGNRSRRDAGSQATAA

Specific function: Confers The Resistance Against Fosmidomycin. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786686, Length=285, Percent_Identity=23.5087719298246, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 45294; Mature: 45163

Theoretical pI: Translated: 10.31; Mature: 10.31

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSLAGLRRACLAPSRESAAMTTAAFDPSRNTLRHDAQVIGLVGLAHGVSHFYHLLLAPL
CCCHHHHHHHHCCCCCCCHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FPWIKAEFGLSYAELGLLMTVFFAVSAVVQTASGFVVDRIGARPVLFGGLAFLGAAALLL
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCHHHHHHHHHHHHHHHHH
STSTGYAMLLFGAGVAGLGNGVFHPADFTLLNKHVSQPRLGHAFSVHGISGNLGWAAAPV
CCCCCCEEEEECCCHHHCCCCCCCCCCHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHH
FLVTIANLATWRVALAAASVVAFSVLAVLLVLRHVLDPRELGSAVGRPKAAQSGAGGSLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCH
GFLKLPQVWVCWAFFLLTTFSAAGIQSFAPTALTQLYGIPFTLATASYTIYMLCSAGGMV
HHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCEEHHHHEEEEEEECCCCEE
VGGFAATRTSNHDRLIALSFTVSGLMAVLVGLNVAPGLLVPVLLGVVGFGAGTAGPSRDL
EECEEECCCCCCCEEEEEHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCE
LVRAAAPAGATGRVYGVVYSGLDIGLASGPLFFGALMDAHLPNWVFFMIGGFQLVSILTA
EEEECCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
VTVGNGNRSRRDAGSQATAA
HHCCCCCCCHHCCCCCCCCC
>Mature Secondary Structure 
PSLAGLRRACLAPSRESAAMTTAAFDPSRNTLRHDAQVIGLVGLAHGVSHFYHLLLAPL
CCHHHHHHHHCCCCCCCHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FPWIKAEFGLSYAELGLLMTVFFAVSAVVQTASGFVVDRIGARPVLFGGLAFLGAAALLL
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCHHHHHHHHHHHHHHHHH
STSTGYAMLLFGAGVAGLGNGVFHPADFTLLNKHVSQPRLGHAFSVHGISGNLGWAAAPV
CCCCCCEEEEECCCHHHCCCCCCCCCCHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHH
FLVTIANLATWRVALAAASVVAFSVLAVLLVLRHVLDPRELGSAVGRPKAAQSGAGGSLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCH
GFLKLPQVWVCWAFFLLTTFSAAGIQSFAPTALTQLYGIPFTLATASYTIYMLCSAGGMV
HHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCEEHHHHEEEEEEECCCCEE
VGGFAATRTSNHDRLIALSFTVSGLMAVLVGLNVAPGLLVPVLLGVVGFGAGTAGPSRDL
EECEEECCCCCCCEEEEEHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCE
LVRAAAPAGATGRVYGVVYSGLDIGLASGPLFFGALMDAHLPNWVFFMIGGFQLVSILTA
EEEECCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
VTVGNGNRSRRDAGSQATAA
HHCCCCCCCHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: fosmidomycin [Cytoplasm]; Proton [Periplasm] [C]

Specific reaction: fosmidomycin [Cytoplasm] + Proton [Periplasm] = fosmidomycin [Periplasm] + Proton [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA