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The map label for this gene is yfhM [H]

Identifier: 73541110

GI number: 73541110

Start: 1532753

End: 1533673

Strand: Direct

Name: yfhM [H]

Synonym: Reut_A1416

Alternate gene names: 73541110

Gene position: 1532753-1533673 (Clockwise)

Preceding gene: 73541109

Following gene: 73541113

Centisome position: 40.27

GC content: 63.41

Gene sequence:

>921_bases
ATGACCGCTCCCGCCGTCATCCGTCATCTGCAGTTCGCCAACCTGCCAAATGGCACGCGCCTGCACTACGCCAGCGCCGG
AGAGCGCGGCAAGCCGCTGATGCTGTTCGTGCATGGATTCCCGGAATTCTGGTTCGAATGGGAAGCGCAGCTTGCCGAAT
TCGGTCGCACCCATTTCGCGGTCGCACCGGACCTGCGCGGCTTCAACCTGTCGAGCAAGCCCGAAGCGGTAGAGGCCTAC
CGCCCGCGCCATATCGTCGAGGACCTGGTGCAGTTCGTCGGCGCCCTCGGCTATGAGCGTTGCATCGTGGTTGCGCATGA
CTGGGGTGGGGCTGTCTGCTGGAACCTTGCCATTCAGTTTCCGCAACTGGTCGAGCAACTGGTCATCATCAATTCACCGC
ATCCGTATCTGTTCGCGAAGGCGCTGGCCAACGATCCGCAGCAGCAGGCAGCGTCGGCCTATATGAACTGGCTGCGCCGG
CCAGGTTCTGAAGCGGTGCTTGCCGCAAACAACTTCGCCATGCTGGAAAGCATGCTGACGGCCGGCGGCGAGCAGCCCGC
ACCGTGGTTCAGCGGCGAGACGCGCGAGAAGTATCTGGCGGCCTGGGCGCAGCCTGGCGAAGGCAGCGCGCATTCGTTGT
CGGGCGGGGTCAACTATTACCGTGCGTCGCCGATGCATCCGCCCGGGCCGGGAGAGGCGCCACCGGACATCTCGCGGCTC
GATCCGGCGGCGTTCGTAGTTCGCGTGCCTACGTTCGTGATCTGGGGAGAGAGGGACCGGGCGCTGCCCAAGTCATTGCT
GGACGGGTTGGATCAGTTCGTGCCGGATATGCGGCTAGAGCGCATTCCGGATGGCACGCATTGGGTAGTGCATGAGGAGC
CGGAACTGGTGAGCCGGTTGATTCGTAGTGCTTTGAAGTAG

Upstream 100 bases:

>100_bases
ATCCGTTCGCGGACAAGCCCGAGGTACGCGCAGGACTGGTTGCCGCGTTGCGCGGCTGATCGACGAACCAACCACACGAG
GCCCGCGCATGGAGACCCCC

Downstream 100 bases:

>100_bases
GTTGGTGGGTTCTGGTCGGACTGGGGCGCCGCCGACTTCTGTCGCTCGGACAAGAAGTAAGTCGCCGGCTACGCCGGCGA
AACAGCGGCGCCGGTCAAGG

Product: Alpha/beta hydrolase fold

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 306; Mature: 305

Protein sequence:

>306_residues
MTAPAVIRHLQFANLPNGTRLHYASAGERGKPLMLFVHGFPEFWFEWEAQLAEFGRTHFAVAPDLRGFNLSSKPEAVEAY
RPRHIVEDLVQFVGALGYERCIVVAHDWGGAVCWNLAIQFPQLVEQLVIINSPHPYLFAKALANDPQQQAASAYMNWLRR
PGSEAVLAANNFAMLESMLTAGGEQPAPWFSGETREKYLAAWAQPGEGSAHSLSGGVNYYRASPMHPPGPGEAPPDISRL
DPAAFVVRVPTFVIWGERDRALPKSLLDGLDQFVPDMRLERIPDGTHWVVHEEPELVSRLIRSALK

Sequences:

>Translated_306_residues
MTAPAVIRHLQFANLPNGTRLHYASAGERGKPLMLFVHGFPEFWFEWEAQLAEFGRTHFAVAPDLRGFNLSSKPEAVEAY
RPRHIVEDLVQFVGALGYERCIVVAHDWGGAVCWNLAIQFPQLVEQLVIINSPHPYLFAKALANDPQQQAASAYMNWLRR
PGSEAVLAANNFAMLESMLTAGGEQPAPWFSGETREKYLAAWAQPGEGSAHSLSGGVNYYRASPMHPPGPGEAPPDISRL
DPAAFVVRVPTFVIWGERDRALPKSLLDGLDQFVPDMRLERIPDGTHWVVHEEPELVSRLIRSALK
>Mature_305_residues
TAPAVIRHLQFANLPNGTRLHYASAGERGKPLMLFVHGFPEFWFEWEAQLAEFGRTHFAVAPDLRGFNLSSKPEAVEAYR
PRHIVEDLVQFVGALGYERCIVVAHDWGGAVCWNLAIQFPQLVEQLVIINSPHPYLFAKALANDPQQQAASAYMNWLRRP
GSEAVLAANNFAMLESMLTAGGEQPAPWFSGETREKYLAAWAQPGEGSAHSLSGGVNYYRASPMHPPGPGEAPPDISRLD
PAAFVVRVPTFVIWGERDRALPKSLLDGLDQFVPDMRLERIPDGTHWVVHEEPELVSRLIRSALK

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. Epoxide hydrolase family [H]

Homologues:

Organism=Homo sapiens, GI218777837, Length=311, Percent_Identity=32.475884244373, Blast_Score=195, Evalue=5e-50,
Organism=Homo sapiens, GI218777840, Length=300, Percent_Identity=34.3333333333333, Blast_Score=158, Evalue=5e-39,
Organism=Homo sapiens, GI13376164, Length=300, Percent_Identity=34.3333333333333, Blast_Score=158, Evalue=5e-39,
Organism=Homo sapiens, GI27597073, Length=306, Percent_Identity=22.5490196078431, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17554012, Length=291, Percent_Identity=35.3951890034364, Blast_Score=178, Evalue=4e-45,
Organism=Caenorhabditis elegans, GI17562298, Length=291, Percent_Identity=32.3024054982818, Blast_Score=172, Evalue=2e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: NA

Molecular weight: Translated: 34038; Mature: 33907

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAPAVIRHLQFANLPNGTRLHYASAGERGKPLMLFVHGFPEFWFEWEAQLAEFGRTHFA
CCCHHHHHHHHHCCCCCCCEEEEECCCCCCCEEEEEEECCCHHHHHHHHHHHHCCCCEEE
VAPDLRGFNLSSKPEAVEAYRPRHIVEDLVQFVGALGYERCIVVAHDWGGAVCWNLAIQF
ECCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHH
PQLVEQLVIINSPHPYLFAKALANDPQQQAASAYMNWLRRPGSEAVLAANNFAMLESMLT
HHHHHHHHEECCCCCHHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHH
AGGEQPAPWFSGETREKYLAAWAQPGEGSAHSLSGGVNYYRASPMHPPGPGEAPPDISRL
CCCCCCCCCCCCCHHHHHHHHHCCCCCCCCHHCCCCCCEEECCCCCCCCCCCCCCCHHHC
DPAAFVVRVPTFVIWGERDRALPKSLLDGLDQFVPDMRLERIPDGTHWVVHEEPELVSRL
CHHHEEEECCEEEEECCCCCCHHHHHHHHHHHHCCCHHHHHCCCCCEEEEECCHHHHHHH
IRSALK
HHHHCC
>Mature Secondary Structure 
TAPAVIRHLQFANLPNGTRLHYASAGERGKPLMLFVHGFPEFWFEWEAQLAEFGRTHFA
CCHHHHHHHHHCCCCCCCEEEEECCCCCCCEEEEEEECCCHHHHHHHHHHHHCCCCEEE
VAPDLRGFNLSSKPEAVEAYRPRHIVEDLVQFVGALGYERCIVVAHDWGGAVCWNLAIQF
ECCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHH
PQLVEQLVIINSPHPYLFAKALANDPQQQAASAYMNWLRRPGSEAVLAANNFAMLESMLT
HHHHHHHHEECCCCCHHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHH
AGGEQPAPWFSGETREKYLAAWAQPGEGSAHSLSGGVNYYRASPMHPPGPGEAPPDISRL
CCCCCCCCCCCCCHHHHHHHHHCCCCCCCCHHCCCCCCEEECCCCCCCCCCCCCCCHHHC
DPAAFVVRVPTFVIWGERDRALPKSLLDGLDQFVPDMRLERIPDGTHWVVHEEPELVSRL
CHHHEEEECCEEEEECCCCCCHHHHHHHHHHHHCCCHHHHHCCCCCEEEEECCHHHHHHH
IRSALK
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8946165; 9384377 [H]