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The map label for this gene is livK [C]

Identifier: 73541093

GI number: 73541093

Start: 1512896

End: 1514146

Strand: Direct

Name: livK [C]

Synonym: Reut_A1399

Alternate gene names: 73541093

Gene position: 1512896-1514146 (Clockwise)

Preceding gene: 73541092

Following gene: 73541094

Centisome position: 39.74

GC content: 61.87

Gene sequence:

>1251_bases
ATGACCAAAATGCGTCCGCTGGTGGCTGGCGTGGCCGTGTTCGCGGCACTGGGTTCTGCGCTGGTTTCAGGCACGGCACT
CGCAGATACGGTGAAGATTGCCTTCATCGATCCGCTTTCGGGGCTGATGGCCCCCGTTGGACAGAACCAGCTCAAGAGCT
GGCAGTACGTGGCCGAGGTAGCCAACCAGAAGGGTTGGGGTGGCCCGCACAAGTTCGAGGTAGTGGGCTTCGACAACAAG
CTGTCGCCGCAGGAGAGCCTGACCATCCTCAAGCAGGTGGCCGACCAGGGCATCCGCTACATCGTCCAGGGCAACGGCTC
GTCGGTGGGCCTGGCGTTGGAAGACGCCGTTGCCAAGCACAACGAGCGCAATCCGGGCAAGGAAATCGTCTACCTGAACT
ACGCAGCGGTAGACCCGGACATGACCAACAGCAAGTGCAACTACTGGCATTTCCGGCTCGACGCGAACTCGGACATGAAG
ATGGAGGCCCTGACCACGTACCTGGCCAAGGACCCCAACGTCAAGAAGGTCTACCTGATCAACCAGAACTACTCGTTCGG
CCACCAGGTCGCGCGCGCGGCCAAGGACTACCTGAAGCGCAAGCGTCCGGATATCCAGATCGTCGGAGAAGACCTGCATC
CGCTCGCGCAGGTGAAGGACTTCGCGCCGTACGCGTCCAAGATCAAGGCGTCGGGCGCCGATACGGTGATTACGGGCAAC
TGGGGCAGCGACCTCGCGCTGCTGATCAAGGCGGGCAAGGACGCCGGCCTGACCACCAACTACTACACGTACTACGCCGG
CACCACCGGCGTGCCGACCGCCATGGGCGCCGCCGGTGCCGATCACGTCAAGTACGTGGGCTACTACAACCCGAACAACG
AGGGCTTCAAGGGCGCCGACATCATCGAGGGCTACAAGAAGAAGTACAACGACGACTTCTACGTGATGGCCGCCTACACC
GGCGTGGCCATGCTGGCCAAGGCGGTGAAGGAATCCGGTTCCACGGATCCGGTCAAGGTCGCCAAGGCCATGGAAGGCAT
CAAGGTCGACAGCATGAATGGCCCGGTCGAGATGCGAAAGACCGACCACCAGGCCCAGCAGTCGCTCGTGGTGGCCACCT
GGACCAAGGTCAACGGCAAGGACATCAAGTTCGACCAGGAAAACACCGGCTACGGCTGGAAGACCAATGCGCTGATGGAC
CAGTACGTTGCCGCGCAGCCGACTTCCTGCCAGATGAAGCGGCCGGGCTGA

Upstream 100 bases:

>100_bases
GCGGCACGGTGTTGGCGAGGCAGCCGGGCGAGCAACAACAGGGTCCGCCCGGCGAGCCGCAATCGACGACAAGCCAACGA
CAAGAGTGAAGGAGACAGGT

Downstream 100 bases:

>100_bases
TCCTGCCCACGGCGGGCCGGCCGGCAGCATAAAGCCGGCCGCCCGATCCTGCATACTTTCGGTAGAAGACCGGGGAGCGT
CCGGGCATGCATGCCATGCC

Product: extracellular ligand-binding receptor

Products: ADP; phosphate; L-leucine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 416; Mature: 415

Protein sequence:

>416_residues
MTKMRPLVAGVAVFAALGSALVSGTALADTVKIAFIDPLSGLMAPVGQNQLKSWQYVAEVANQKGWGGPHKFEVVGFDNK
LSPQESLTILKQVADQGIRYIVQGNGSSVGLALEDAVAKHNERNPGKEIVYLNYAAVDPDMTNSKCNYWHFRLDANSDMK
MEALTTYLAKDPNVKKVYLINQNYSFGHQVARAAKDYLKRKRPDIQIVGEDLHPLAQVKDFAPYASKIKASGADTVITGN
WGSDLALLIKAGKDAGLTTNYYTYYAGTTGVPTAMGAAGADHVKYVGYYNPNNEGFKGADIIEGYKKKYNDDFYVMAAYT
GVAMLAKAVKESGSTDPVKVAKAMEGIKVDSMNGPVEMRKTDHQAQQSLVVATWTKVNGKDIKFDQENTGYGWKTNALMD
QYVAAQPTSCQMKRPG

Sequences:

>Translated_416_residues
MTKMRPLVAGVAVFAALGSALVSGTALADTVKIAFIDPLSGLMAPVGQNQLKSWQYVAEVANQKGWGGPHKFEVVGFDNK
LSPQESLTILKQVADQGIRYIVQGNGSSVGLALEDAVAKHNERNPGKEIVYLNYAAVDPDMTNSKCNYWHFRLDANSDMK
MEALTTYLAKDPNVKKVYLINQNYSFGHQVARAAKDYLKRKRPDIQIVGEDLHPLAQVKDFAPYASKIKASGADTVITGN
WGSDLALLIKAGKDAGLTTNYYTYYAGTTGVPTAMGAAGADHVKYVGYYNPNNEGFKGADIIEGYKKKYNDDFYVMAAYT
GVAMLAKAVKESGSTDPVKVAKAMEGIKVDSMNGPVEMRKTDHQAQQSLVVATWTKVNGKDIKFDQENTGYGWKTNALMD
QYVAAQPTSCQMKRPG
>Mature_415_residues
TKMRPLVAGVAVFAALGSALVSGTALADTVKIAFIDPLSGLMAPVGQNQLKSWQYVAEVANQKGWGGPHKFEVVGFDNKL
SPQESLTILKQVADQGIRYIVQGNGSSVGLALEDAVAKHNERNPGKEIVYLNYAAVDPDMTNSKCNYWHFRLDANSDMKM
EALTTYLAKDPNVKKVYLINQNYSFGHQVARAAKDYLKRKRPDIQIVGEDLHPLAQVKDFAPYASKIKASGADTVITGNW
GSDLALLIKAGKDAGLTTNYYTYYAGTTGVPTAMGAAGADHVKYVGYYNPNNEGFKGADIIEGYKKKYNDDFYVMAAYTG
VAMLAKAVKESGSTDPVKVAKAMEGIKVDSMNGPVEMRKTDHQAQQSLVVATWTKVNGKDIKFDQENTGYGWKTNALMDQ
YVAAQPTSCQMKRPG

Specific function: Component of an amino-acid transport system (Potential) [H]

COG id: COG0683

COG function: function code E; ABC-type branched-chain amino acid transport systems, periplasmic component

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the leucine-binding protein family [H]

Homologues:

Organism=Escherichia coli, GI48994941, Length=363, Percent_Identity=21.763085399449, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1789867, Length=355, Percent_Identity=22.5352112676056, Blast_Score=76, Evalue=5e-15,

Paralogues:

None

Copy number: 240 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000709 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 45273; Mature: 45142

Theoretical pI: Translated: 9.21; Mature: 9.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKMRPLVAGVAVFAALGSALVSGTALADTVKIAFIDPLSGLMAPVGQNQLKSWQYVAEV
CCCCHHHHHHHHHHHHHHHHHHCCCHHHHEEEEEEECCHHHHHCCCCHHHHHHHHHHHHH
ANQKGWGGPHKFEVVGFDNKLSPQESLTILKQVADQGIRYIVQGNGSSVGLALEDAVAKH
HHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEECCCCEEEEEHHHHHHHC
NERNPGKEIVYLNYAAVDPDMTNSKCNYWHFRLDANSDMKMEALTTYLAKDPNVKKVYLI
CCCCCCCEEEEEEEEEECCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCCEEEEEE
NQNYSFGHQVARAAKDYLKRKRPDIQIVGEDLHPLAQVKDFAPYASKIKASGADTVITGN
ECCCCHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHCCHHHHHHHCCCCCEEEECC
WGSDLALLIKAGKDAGLTTNYYTYYAGTTGVPTAMGAAGADHVKYVGYYNPNNEGFKGAD
CCCCEEEEEECCCCCCCEECEEEEECCCCCCCHHHCCCCCCCEEEEEEECCCCCCCCCHH
IIEGYKKKYNDDFYVMAAYTGVAMLAKAVKESGSTDPVKVAKAMEGIKVDSMNGPVEMRK
HHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCEEECCCCCCHHHH
TDHQAQQSLVVATWTKVNGKDIKFDQENTGYGWKTNALMDQYVAAQPTSCQMKRPG
HHHHHHHCEEEEEEEECCCCEEEECCCCCCCCEEHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
TKMRPLVAGVAVFAALGSALVSGTALADTVKIAFIDPLSGLMAPVGQNQLKSWQYVAEV
CCCHHHHHHHHHHHHHHHHHHCCCHHHHEEEEEEECCHHHHHCCCCHHHHHHHHHHHHH
ANQKGWGGPHKFEVVGFDNKLSPQESLTILKQVADQGIRYIVQGNGSSVGLALEDAVAKH
HHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEECCCCEEEEEHHHHHHHC
NERNPGKEIVYLNYAAVDPDMTNSKCNYWHFRLDANSDMKMEALTTYLAKDPNVKKVYLI
CCCCCCCEEEEEEEEEECCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCCEEEEEE
NQNYSFGHQVARAAKDYLKRKRPDIQIVGEDLHPLAQVKDFAPYASKIKASGADTVITGN
ECCCCHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHCCHHHHHHHCCCCCEEEECC
WGSDLALLIKAGKDAGLTTNYYTYYAGTTGVPTAMGAAGADHVKYVGYYNPNNEGFKGAD
CCCCEEEEEECCCCCCCEECEEEEECCCCCCCHHHCCCCCCCEEEEEEECCCCCCCCCHH
IIEGYKKKYNDDFYVMAAYTGVAMLAKAVKESGSTDPVKVAKAMEGIKVDSMNGPVEMRK
HHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCEEECCCCCCHHHH
TDHQAQQSLVVATWTKVNGKDIKFDQENTGYGWKTNALMDQYVAAQPTSCQMKRPG
HHHHHHHCEEEEEEEECCCCEEEECCCCCCCCEEHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-leucine [Periplasm]; H2O [C]

Specific reaction: ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA