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The map label for this gene is cobT [H]

Identifier: 73540364

GI number: 73540364

Start: 706954

End: 707994

Strand: Direct

Name: cobT [H]

Synonym: Reut_A0658

Alternate gene names: 73540364

Gene position: 706954-707994 (Clockwise)

Preceding gene: 73540363

Following gene: 73540365

Centisome position: 18.57

GC content: 69.64

Gene sequence:

>1041_bases
ATGCTGTTTCCAGAAATCGCCCCCCTCGACGACGCGCTGCGTCCGGCCCTGCGGGCCGCCATCGACGACAAGACCAAGCC
GCTCGGCGCACTCGGCCGGCTCGAAGACCTCGCCATGCAGGTCGGCCTGATCTGCGGCACAACGCAACCGGCACTGAAAC
GACCCACCGTCATCGTCTTTGCCGGCGACCATGGTGTTGCTGATGCGGGCGTCAGCGCGTATCCGGCCGAGGTCACCGCG
CAGATGGTGCTCAATTTCCTGAAGGGCGGAGCGGCCATCAACGTGTTCTCGCGCCTGCACGGCATTGCGCTGGAAGTCGT
CGATGCCGGCGTGCGTGTGCCGCTGCCCGCGTCGCCGGGACTGGTCAATTGCCGGATCGCGGACGGCACGCAGAACTTCG
CCGAGACGCAGGCCATGCGTGCGGAGCAGGCCAGCGCCGCGATGATGGCCGGCATGGCGCGCGTGCTGCGCGCCGCGCAG
CAGGGCTGCAACGTGATCGGTTTTGGCGAGATGGGCATCGGCAACACCTCGTCCGCAGCGTGCCTCATGAGCCGGCTCAC
GGGCGTGCCGCTGGCGGACTGCATCGGCCGCGGCACCGGGCTCGACGACGCCGGCCTTGCGCGCAAGCGCGAGGTGCTGG
AGCGCGCGCTTGCGCTGCACGCGGATGCCGTCGCGCCGCTCGATGCATTGGCCGCATTCGGCGGTTTCGAGATCGCGATG
ATGGCGGGCGCCTTCCTGGCCGCGGCCGCGAGCCGCATGGTGATCCTGGTCGACGGCTTCATTGCCTCGGCCGCACTGCT
GGTGGCGCACGGCATCGACGCCCGCGTGCTGCAGTACTGCGTGTTTTCGCACTGCTCGCATGAACGCGGCCACCGCGCAC
TGCTCGACCACTTCAAGGCCGAGCCGCTGCTGGCGCTGGACCTGCGTCTCGGCGAAGGGACCGGCGCGGCGCTTGCGTGG
CCGCTCGTGTCGTCGGCCGCCGCTTTCCTGAACGAGATGGCCACGTTCAGCGGTGCAGGCGTCAGCGGCGCCTCGGCCTG
A

Upstream 100 bases:

>100_bases
GTCAAGCACGCGTTCCAGCAGGGCATCAAGGCGCAGCGCGGCGTGGAGATGTAGCGGTACACTGCGCCCGATTCATTTTT
ATCCGTATTCATTGCGCACC

Downstream 100 bases:

>100_bases
CCGCCGCATGGCCGACGAACTGCGCTTCTTCCTGACCGCGCTCGGCTACTTCACGCGCGTGCCGCTGCCGTCGCCGCTGG
CGCAGTGGGTTGGCTATGAG

Product: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase

Products: NA

Alternate protein names: NN:DBI PRT; N(1)-alpha-phosphoribosyltransferase [H]

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MLFPEIAPLDDALRPALRAAIDDKTKPLGALGRLEDLAMQVGLICGTTQPALKRPTVIVFAGDHGVADAGVSAYPAEVTA
QMVLNFLKGGAAINVFSRLHGIALEVVDAGVRVPLPASPGLVNCRIADGTQNFAETQAMRAEQASAAMMAGMARVLRAAQ
QGCNVIGFGEMGIGNTSSAACLMSRLTGVPLADCIGRGTGLDDAGLARKREVLERALALHADAVAPLDALAAFGGFEIAM
MAGAFLAAAASRMVILVDGFIASAALLVAHGIDARVLQYCVFSHCSHERGHRALLDHFKAEPLLALDLRLGEGTGAALAW
PLVSSAAAFLNEMATFSGAGVSGASA

Sequences:

>Translated_346_residues
MLFPEIAPLDDALRPALRAAIDDKTKPLGALGRLEDLAMQVGLICGTTQPALKRPTVIVFAGDHGVADAGVSAYPAEVTA
QMVLNFLKGGAAINVFSRLHGIALEVVDAGVRVPLPASPGLVNCRIADGTQNFAETQAMRAEQASAAMMAGMARVLRAAQ
QGCNVIGFGEMGIGNTSSAACLMSRLTGVPLADCIGRGTGLDDAGLARKREVLERALALHADAVAPLDALAAFGGFEIAM
MAGAFLAAAASRMVILVDGFIASAALLVAHGIDARVLQYCVFSHCSHERGHRALLDHFKAEPLLALDLRLGEGTGAALAW
PLVSSAAAFLNEMATFSGAGVSGASA
>Mature_346_residues
MLFPEIAPLDDALRPALRAAIDDKTKPLGALGRLEDLAMQVGLICGTTQPALKRPTVIVFAGDHGVADAGVSAYPAEVTA
QMVLNFLKGGAAINVFSRLHGIALEVVDAGVRVPLPASPGLVNCRIADGTQNFAETQAMRAEQASAAMMAGMARVLRAAQ
QGCNVIGFGEMGIGNTSSAACLMSRLTGVPLADCIGRGTGLDDAGLARKREVLERALALHADAVAPLDALAAFGGFEIAM
MAGAFLAAAASRMVILVDGFIASAALLVAHGIDARVLQYCVFSHCSHERGHRALLDHFKAEPLLALDLRLGEGTGAALAW
PLVSSAAAFLNEMATFSGAGVSGASA

Specific function: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) [H]

COG id: COG2038

COG function: function code H; NaMN:DMB phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobT family [H]

Homologues:

Organism=Escherichia coli, GI1788300, Length=323, Percent_Identity=36.2229102167183, Blast_Score=196, Evalue=2e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003200
- InterPro:   IPR023195
- InterPro:   IPR017846 [H]

Pfam domain/function: PF02277 DBI_PRT [H]

EC number: =2.4.2.21 [H]

Molecular weight: Translated: 35509; Mature: 35509

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: PS00358 RIBOSOMAL_L5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFPEIAPLDDALRPALRAAIDDKTKPLGALGRLEDLAMQVGLICGTTQPALKRPTVIVF
CCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHCCEEEEE
AGDHGVADAGVSAYPAEVTAQMVLNFLKGGAAINVFSRLHGIALEVVDAGVRVPLPASPG
ECCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCEECCCCCCC
LVNCRIADGTQNFAETQAMRAEQASAAMMAGMARVLRAAQQGCNVIGFGEMGIGNTSSAA
EEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCHHHH
CLMSRLTGVPLADCIGRGTGLDDAGLARKREVLERALALHADAVAPLDALAAFGGFEIAM
HHHHHHCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHH
MAGAFLAAAASRMVILVDGFIASAALLVAHGIDARVLQYCVFSHCSHERGHRALLDHFKA
HHHHHHHHHHCCEEEEECCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHCC
EPLLALDLRLGEGTGAALAWPLVSSAAAFLNEMATFSGAGVSGASA
CCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MLFPEIAPLDDALRPALRAAIDDKTKPLGALGRLEDLAMQVGLICGTTQPALKRPTVIVF
CCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHCCEEEEE
AGDHGVADAGVSAYPAEVTAQMVLNFLKGGAAINVFSRLHGIALEVVDAGVRVPLPASPG
ECCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCEECCCCCCC
LVNCRIADGTQNFAETQAMRAEQASAAMMAGMARVLRAAQQGCNVIGFGEMGIGNTSSAA
EEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCHHHH
CLMSRLTGVPLADCIGRGTGLDDAGLARKREVLERALALHADAVAPLDALAAFGGFEIAM
HHHHHHCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHH
MAGAFLAAAASRMVILVDGFIASAALLVAHGIDARVLQYCVFSHCSHERGHRALLDHFKA
HHHHHHHHHHCCEEEEECCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHCC
EPLLALDLRLGEGTGAALAWPLVSSAAAFLNEMATFSGAGVSGASA
CCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA