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The map label for this gene is cbbA [H]

Identifier: 73540263

GI number: 73540263

Start: 602795

End: 603859

Strand: Reverse

Name: cbbA [H]

Synonym: Reut_A0557

Alternate gene names: 73540263

Gene position: 603859-602795 (Counterclockwise)

Preceding gene: 73540264

Following gene: 73540262

Centisome position: 15.86

GC content: 64.04

Gene sequence:

>1065_bases
ATGCCACTCGTATCGATGCGCCAGCTGCTCGACCACGCTGCCGAAAACGGCTATGGTCTGCCGGCATTCAACGTGAACAA
CCTCGAGCAGGTCCAGGCCATCATGCAGGCGGCCGACGAGGTCAACGCCCCGGTGATCATGCAGGCCTCCGCAGGTGCCC
GCAAATACGCCGGCGAACACTTCCTGCGCCACCTGATCGAAGCCGCGGTCGAAGCCTACCCGCACATCCCGGTGGTGATG
CACCAGGATCACGGCCAGTCGCCGGCGATCTGCCAGGCCGCGATCGACCTGGGCTTCTCGTCGGTGATGATGGACGGCTC
GCTGCGCGAAGACGGCAAGACTCCGGCCGACTACGAGTACAACGTCGACGTGACCCGCAAGGTCGTGCAACTGTCGCACG
CGATCGGCGTGACCGTCGAAGGCGAACTGGGCTGCCTGGGCTCGCTCGAAACCGGTGAAGCCGGCGAAGAAGACGGCATC
GGCGCCGAAGGCAAGCTGGACCACTCCATGCTGCTGACCGACCCCGAGCAGGCCGCCGACTTCGTCAAGGCCACGCAACT
CGACGCGCTCGCCATCGCCATCGGCACCTCGCACGGCGCGTACAAGTTCACGCGCAAGCCCACGGGCGACATCCTGGCGA
TCAACCGCATCAAGGAAATCCACGCGCGCATCCCGAACACCCACCTGGTGATGCACGGCTCGTCGTCGGTCCCGCAGGAA
CTGCTGGAAGAAATCCGCAAGTTCGGCGGCGACATGAAGGAAACCTACGGTGTGCCGGTCGAGGAAATCCAGGAAGCCAT
CAAGTACGGCGTGCGCAAGATCAACATCGACACCGATATCCGCCTGGCCATGACCGGCGCGATCCGCCGCTTCTTCGTCG
AGAACCCGAGCAAGTTCGACCCGCGCGAATACCTGAAGCCGGCCCGCGAAGCCGCCAAGCAGGTTTGCAAGGCCCGCTAC
ATCGCCTTCGGCTGCGAAGGCCAGGCCGGCAAGATCAAGCCGGTGTCGCTGACCGATATCGCCAGCCAGTACAAGTCGGG
CAAGCTTGCCCAGGTTGTGCAGTAA

Upstream 100 bases:

>100_bases
GCACTACGGCAAGCGGTGCAAAAGGCGCTGCGCCGCAGGCTTGGCCCGCGCCAGCAGAACAAGATTCAGAGACACACCAT
TTACCTTCAGGAGTTTTGAC

Downstream 100 bases:

>100_bases
TGTCCCCTGACCGCCATCCGCGCAAGCGGAAGGCGGTTTGACGTTCCGGCCGCCGCGGCAGCATTCAGTGCCCGGCGGCT
TCGCCGTTTTATCGGAACCA

Product: fructose-1,6-bisphosphate aldolase

Products: NA

Alternate protein names: FBP aldolase; FBPA; Fructose-1,6-bisphosphate aldolase [H]

Number of amino acids: Translated: 354; Mature: 353

Protein sequence:

>354_residues
MPLVSMRQLLDHAAENGYGLPAFNVNNLEQVQAIMQAADEVNAPVIMQASAGARKYAGEHFLRHLIEAAVEAYPHIPVVM
HQDHGQSPAICQAAIDLGFSSVMMDGSLREDGKTPADYEYNVDVTRKVVQLSHAIGVTVEGELGCLGSLETGEAGEEDGI
GAEGKLDHSMLLTDPEQAADFVKATQLDALAIAIGTSHGAYKFTRKPTGDILAINRIKEIHARIPNTHLVMHGSSSVPQE
LLEEIRKFGGDMKETYGVPVEEIQEAIKYGVRKINIDTDIRLAMTGAIRRFFVENPSKFDPREYLKPAREAAKQVCKARY
IAFGCEGQAGKIKPVSLTDIASQYKSGKLAQVVQ

Sequences:

>Translated_354_residues
MPLVSMRQLLDHAAENGYGLPAFNVNNLEQVQAIMQAADEVNAPVIMQASAGARKYAGEHFLRHLIEAAVEAYPHIPVVM
HQDHGQSPAICQAAIDLGFSSVMMDGSLREDGKTPADYEYNVDVTRKVVQLSHAIGVTVEGELGCLGSLETGEAGEEDGI
GAEGKLDHSMLLTDPEQAADFVKATQLDALAIAIGTSHGAYKFTRKPTGDILAINRIKEIHARIPNTHLVMHGSSSVPQE
LLEEIRKFGGDMKETYGVPVEEIQEAIKYGVRKINIDTDIRLAMTGAIRRFFVENPSKFDPREYLKPAREAAKQVCKARY
IAFGCEGQAGKIKPVSLTDIASQYKSGKLAQVVQ
>Mature_353_residues
PLVSMRQLLDHAAENGYGLPAFNVNNLEQVQAIMQAADEVNAPVIMQASAGARKYAGEHFLRHLIEAAVEAYPHIPVVMH
QDHGQSPAICQAAIDLGFSSVMMDGSLREDGKTPADYEYNVDVTRKVVQLSHAIGVTVEGELGCLGSLETGEAGEEDGIG
AEGKLDHSMLLTDPEQAADFVKATQLDALAIAIGTSHGAYKFTRKPTGDILAINRIKEIHARIPNTHLVMHGSSSVPQEL
LEEIRKFGGDMKETYGVPVEEIQEAIKYGVRKINIDTDIRLAMTGAIRRFFVENPSKFDPREYLKPAREAAKQVCKARYI
AFGCEGQAGKIKPVSLTDIASQYKSGKLAQVVQ

Specific function: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3- phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis [H]

COG id: COG0191

COG function: function code G; Fructose/tagatose bisphosphate aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class II fructose-bisphosphate aldolase family [H]

Homologues:

Organism=Escherichia coli, GI87082041, Length=329, Percent_Identity=33.1306990881459, Blast_Score=172, Evalue=2e-44,
Organism=Escherichia coli, GI1789526, Length=319, Percent_Identity=32.9153605015674, Blast_Score=170, Evalue=1e-43,
Organism=Escherichia coli, GI1788072, Length=329, Percent_Identity=30.0911854103343, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1789293, Length=357, Percent_Identity=24.9299719887955, Blast_Score=96, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006412
- InterPro:   IPR000771 [H]

Pfam domain/function: PF01116 F_bP_aldolase [H]

EC number: =4.1.2.13 [H]

Molecular weight: Translated: 38522; Mature: 38391

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: PS00602 ALDOLASE_CLASS_II_1 ; PS00806 ALDOLASE_CLASS_II_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLVSMRQLLDHAAENGYGLPAFNVNNLEQVQAIMQAADEVNAPVIMQASAGARKYAGEH
CCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHH
FLRHLIEAAVEAYPHIPVVMHQDHGQSPAICQAAIDLGFSSVMMDGSLREDGKTPADYEY
HHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCEEE
NVDVTRKVVQLSHAIGVTVEGELGCLGSLETGEAGEEDGIGAEGKLDHSMLLTDPEQAAD
CHHHHHHHHHHHHHHCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCHHHHHH
FVKATQLDALAIAIGTSHGAYKFTRKPTGDILAINRIKEIHARIPNTHLVMHGSSSVPQE
HHHHHHHCEEEEEEECCCCCEEECCCCCCCEEEHHHHHHHHHHCCCCEEEEECCCCCHHH
LLEEIRKFGGDMKETYGVPVEEIQEAIKYGVRKINIDTDIRLAMTGAIRRFFVENPSKFD
HHHHHHHHCCCHHHHCCCCHHHHHHHHHHCCEEECCCCCCHHHHHHHHHHHHHCCCCCCC
PREYLKPAREAAKQVCKARYIAFGCEGQAGKIKPVSLTDIASQYKSGKLAQVVQ
HHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCHHHHHHHHHCCCCHHHHCC
>Mature Secondary Structure 
PLVSMRQLLDHAAENGYGLPAFNVNNLEQVQAIMQAADEVNAPVIMQASAGARKYAGEH
CHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHH
FLRHLIEAAVEAYPHIPVVMHQDHGQSPAICQAAIDLGFSSVMMDGSLREDGKTPADYEY
HHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCEEE
NVDVTRKVVQLSHAIGVTVEGELGCLGSLETGEAGEEDGIGAEGKLDHSMLLTDPEQAAD
CHHHHHHHHHHHHHHCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCHHHHHH
FVKATQLDALAIAIGTSHGAYKFTRKPTGDILAINRIKEIHARIPNTHLVMHGSSSVPQE
HHHHHHHCEEEEEEECCCCCEEECCCCCCCEEEHHHHHHHHHHCCCCEEEEECCCCCHHH
LLEEIRKFGGDMKETYGVPVEEIQEAIKYGVRKINIDTDIRLAMTGAIRRFFVENPSKFD
HHHHHHHHCCCHHHHCCCCHHHHHHHHHHCCEEECCCCCCHHHHHHHHHHHHHCCCCCCC
PREYLKPAREAAKQVCKARYIAFGCEGQAGKIKPVSLTDIASQYKSGKLAQVVQ
HHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCHHHHHHHHHCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8550527 [H]