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The map label for this gene is maiA [H]

Identifier: 73540039

GI number: 73540039

Start: 362658

End: 363305

Strand: Direct

Name: maiA [H]

Synonym: Reut_A0333

Alternate gene names: 73540039

Gene position: 362658-363305 (Clockwise)

Preceding gene: 73540038

Following gene: 73540041

Centisome position: 9.53

GC content: 64.04

Gene sequence:

>648_bases
ATGAAGCTCTACAGCTATTTCCGCAGCTCGGCGTCCTATCGCGTGCGTATCGCGCTGGAGCTGAAGGGCCTGCCGTACGA
GTACGTGCCCGTGCACCTGCTCAAGGACGGTGGCCAGCAGTTGCTGCCCGAGTTCCGCGCGGTGAATCCTGACGGACTCG
TGCCGGCGCTGGTGCTCGACGATGGCAACGTGCTGCAGCAGTCCGTGGCCATGATCGAGTATCTGGATGAGATCCATCCA
GAACCGAAGCTGCTGCCCGGCAATGCACTCGACCGCGCCTACGTGCGCGGCCTTGCGCTGGAGGTCGCGTGCGAGATCCA
TCCGCTGAACAACCTGCGCGTGCTGAAGTACGTCAAGCGCACGCTGGGCGTCGCCGACGAGGCGAAGGACGCGTGGTATC
GCCACTGGATCGAACTGGGCTTCGCCTCGTTCGAAGCCAATCTGGAACGCCAGGGCAAGGCCGGCCGCTTCTGCTTCGGC
GATACGCCGACGCTGGCCGATATCTGCCTGGTGCCGCAGGTGTTCAACGCGCAGCGCTTCAATATCGACGTGAGCCGCTA
CCCGACCATCGCGCGGATCCAGGAAGCGTGCATGGAACTGCCGGCGTTCCAGAAGGCCCAGCCGAAGGAACAGCCTGACG
CGGAGTGA

Upstream 100 bases:

>100_bases
AGCGGCACGCCCGAAGGCGTGGGCCCGGTAGTCAAGGGCGACGTCATGCAGTGCCATGTCGGCGGCGTGGGCGACCTGAC
CATCAAAGTGGTCTGAACCG

Downstream 100 bases:

>100_bases
TGCGCGCGGAAAGTGCCCATGAAAAACGCCCCGGGTTTGCCGGGGCGTTTTTTTCTTTCGGGCGATGTCATCAACCGAGC
AGCGCGTCGGCAAATTCCTC

Product: maleylacetoacetate isomerase

Products: NA

Alternate protein names: MAAI [H]

Number of amino acids: Translated: 215; Mature: 215

Protein sequence:

>215_residues
MKLYSYFRSSASYRVRIALELKGLPYEYVPVHLLKDGGQQLLPEFRAVNPDGLVPALVLDDGNVLQQSVAMIEYLDEIHP
EPKLLPGNALDRAYVRGLALEVACEIHPLNNLRVLKYVKRTLGVADEAKDAWYRHWIELGFASFEANLERQGKAGRFCFG
DTPTLADICLVPQVFNAQRFNIDVSRYPTIARIQEACMELPAFQKAQPKEQPDAE

Sequences:

>Translated_215_residues
MKLYSYFRSSASYRVRIALELKGLPYEYVPVHLLKDGGQQLLPEFRAVNPDGLVPALVLDDGNVLQQSVAMIEYLDEIHP
EPKLLPGNALDRAYVRGLALEVACEIHPLNNLRVLKYVKRTLGVADEAKDAWYRHWIELGFASFEANLERQGKAGRFCFG
DTPTLADICLVPQVFNAQRFNIDVSRYPTIARIQEACMELPAFQKAQPKEQPDAE
>Mature_215_residues
MKLYSYFRSSASYRVRIALELKGLPYEYVPVHLLKDGGQQLLPEFRAVNPDGLVPALVLDDGNVLQQSVAMIEYLDEIHP
EPKLLPGNALDRAYVRGLALEVACEIHPLNNLRVLKYVKRTLGVADEAKDAWYRHWIELGFASFEANLERQGKAGRFCFG
DTPTLADICLVPQVFNAQRFNIDVSRYPTIARIQEACMELPAFQKAQPKEQPDAE

Specific function: Unknown

COG id: COG0625

COG function: function code O; Glutathione S-transferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GST N-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI22202624, Length=212, Percent_Identity=49.5283018867925, Blast_Score=197, Evalue=5e-51,
Organism=Homo sapiens, GI194440732, Length=212, Percent_Identity=40.5660377358491, Blast_Score=142, Evalue=2e-34,
Organism=Homo sapiens, GI22202622, Length=161, Percent_Identity=44.7204968944099, Blast_Score=130, Evalue=6e-31,
Organism=Caenorhabditis elegans, GI17551302, Length=213, Percent_Identity=41.7840375586854, Blast_Score=163, Evalue=5e-41,
Organism=Caenorhabditis elegans, GI17510461, Length=213, Percent_Identity=40.8450704225352, Blast_Score=154, Evalue=4e-38,
Organism=Caenorhabditis elegans, GI17556142, Length=214, Percent_Identity=42.5233644859813, Blast_Score=142, Evalue=1e-34,
Organism=Drosophila melanogaster, GI24645375, Length=212, Percent_Identity=46.6981132075472, Blast_Score=186, Evalue=7e-48,
Organism=Drosophila melanogaster, GI21355859, Length=212, Percent_Identity=46.6981132075472, Blast_Score=186, Evalue=8e-48,
Organism=Drosophila melanogaster, GI45553325, Length=212, Percent_Identity=46.6981132075472, Blast_Score=186, Evalue=1e-47,
Organism=Drosophila melanogaster, GI21355857, Length=213, Percent_Identity=42.2535211267606, Blast_Score=168, Evalue=3e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010987
- InterPro:   IPR004045
- InterPro:   IPR017933
- InterPro:   IPR004046
- InterPro:   IPR005955
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00043 GST_C; PF02798 GST_N [H]

EC number: =5.2.1.2 [H]

Molecular weight: Translated: 24318; Mature: 24318

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLYSYFRSSASYRVRIALELKGLPYEYVPVHLLKDGGQQLLPEFRAVNPDGLVPALVLD
CCHHHHHHCCCCEEEEEEEEECCCCCCHHHHEEECCCCHHHHHHHHCCCCCCCEEEEEEC
DGNVLQQSVAMIEYLDEIHPEPKLLPGNALDRAYVRGLALEVACEIHPLNNLRVLKYVKR
CCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHEEEEEEECCCCCHHHHHHHHH
TLGVADEAKDAWYRHWIELGFASFEANLERQGKAGRFCFGDTPTLADICLVPQVFNAQRF
HHCCCCHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCEEECCCCCHHHHHHHHHHHCCEEE
NIDVSRYPTIARIQEACMELPAFQKAQPKEQPDAE
EEEHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKLYSYFRSSASYRVRIALELKGLPYEYVPVHLLKDGGQQLLPEFRAVNPDGLVPALVLD
CCHHHHHHCCCCEEEEEEEEECCCCCCHHHHEEECCCCHHHHHHHHCCCCCCCEEEEEEC
DGNVLQQSVAMIEYLDEIHPEPKLLPGNALDRAYVRGLALEVACEIHPLNNLRVLKYVKR
CCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHEEEEEEECCCCCHHHHHHHHH
TLGVADEAKDAWYRHWIELGFASFEANLERQGKAGRFCFGDTPTLADICLVPQVFNAQRF
HHCCCCHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCEEECCCCCHHHHHHHHHHHCCEEE
NIDVSRYPTIARIQEACMELPAFQKAQPKEQPDAE
EEEHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]