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The map label for this gene is ycgM [C]

Identifier: 73540038

GI number: 73540038

Start: 361952

End: 362653

Strand: Direct

Name: ycgM [C]

Synonym: Reut_A0332

Alternate gene names: 73540038

Gene position: 361952-362653 (Clockwise)

Preceding gene: 73540032

Following gene: 73540039

Centisome position: 9.51

GC content: 66.67

Gene sequence:

>702_bases
ATGACCGAATTCGTTTTTGCCCCGCCGGCACCCGTTGGCGTGCCCGTGCGCGGCAGCAACGCTAGCTTCCCGGTGCGCCG
CGTGTATTGCGTCGGCCGCAACTATGCCGCCCATGCCCGCGAAATGGGCTCGGACCCCGATCGCGAGCCGCCGTTCTTCT
TCTGCAAGCCGTCGGACGCGGTCAGCTACGTGGCGGACGGCACCGAGGGCACATTCCCGTATCCGCCCGGCACCAGCAAC
GTCCACTATGAGGTGGAACTGGTCGTGGCGATCGGCAAGGGCGGCAAGGACATTTCGGTCGAGCAGGCAGCCAGCCACGT
GTTCGGCTACGCCGTAGGCCTCGATATGACGCGCCGCGACCTGCAGAACGAATCGAAGAAGACCGGCCGCCCCTGGGAGA
CCGGCAAGGCGTTCGACCGCTCGGCGCCGATCGGCCCGATCGTGCCGGTGTCGGCCATCGGCCATCCGGAAAAGGGCGAG
GTCACGCTGTCCGTCAACGGCGCCGAGAAGCAGCGCGGCGACCTGTCCGACCTGATCTGGTCGGTGCCGGAGATGGTGTC
GTACCTGTCGAAGCTGTTCGAACTGCAGCCGGGCGACCTGATCTTCAGCGGCACGCCCGAAGGCGTGGGCCCGGTAGTCA
AGGGCGACGTCATGCAGTGCCATGTCGGCGGCGTGGGCGACCTGACCATCAAAGTGGTCTGA

Upstream 100 bases:

>100_bases
CGGGCAGGTGTATGCTGTTGCCCTGCTGCGCCCGGGCGGTGTCTGCTGGCGACACTGGTCGCCTGTGCGCAGGAATATCA
GAACAAGCCTGGAGAGATGC

Downstream 100 bases:

>100_bases
ACCGATGAAGCTCTACAGCTATTTCCGCAGCTCGGCGTCCTATCGCGTGCGTATCGCGCTGGAGCTGAAGGGCCTGCCGT
ACGAGTACGTGCCCGTGCAC

Product: 5-carboxymethyl-2-hydroxymuconate delta-isomerase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 233; Mature: 232

Protein sequence:

>233_residues
MTEFVFAPPAPVGVPVRGSNASFPVRRVYCVGRNYAAHAREMGSDPDREPPFFFCKPSDAVSYVADGTEGTFPYPPGTSN
VHYEVELVVAIGKGGKDISVEQAASHVFGYAVGLDMTRRDLQNESKKTGRPWETGKAFDRSAPIGPIVPVSAIGHPEKGE
VTLSVNGAEKQRGDLSDLIWSVPEMVSYLSKLFELQPGDLIFSGTPEGVGPVVKGDVMQCHVGGVGDLTIKVV

Sequences:

>Translated_233_residues
MTEFVFAPPAPVGVPVRGSNASFPVRRVYCVGRNYAAHAREMGSDPDREPPFFFCKPSDAVSYVADGTEGTFPYPPGTSN
VHYEVELVVAIGKGGKDISVEQAASHVFGYAVGLDMTRRDLQNESKKTGRPWETGKAFDRSAPIGPIVPVSAIGHPEKGE
VTLSVNGAEKQRGDLSDLIWSVPEMVSYLSKLFELQPGDLIFSGTPEGVGPVVKGDVMQCHVGGVGDLTIKVV
>Mature_232_residues
TEFVFAPPAPVGVPVRGSNASFPVRRVYCVGRNYAAHAREMGSDPDREPPFFFCKPSDAVSYVADGTEGTFPYPPGTSNV
HYEVELVVAIGKGGKDISVEQAASHVFGYAVGLDMTRRDLQNESKKTGRPWETGKAFDRSAPIGPIVPVSAIGHPEKGEV
TLSVNGAEKQRGDLSDLIWSVPEMVSYLSKLFELQPGDLIFSGTPEGVGPVVKGDVMQCHVGGVGDLTIKVV

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI13654274, Length=207, Percent_Identity=42.9951690821256, Blast_Score=166, Evalue=2e-41,
Organism=Homo sapiens, GI66348062, Length=200, Percent_Identity=43, Blast_Score=161, Evalue=4e-40,
Organism=Homo sapiens, GI215422413, Length=200, Percent_Identity=43, Blast_Score=161, Evalue=5e-40,
Organism=Homo sapiens, GI156231349, Length=256, Percent_Identity=32.8125, Blast_Score=127, Evalue=6e-30,
Organism=Homo sapiens, GI40786394, Length=256, Percent_Identity=32.03125, Blast_Score=124, Evalue=9e-29,
Organism=Escherichia coli, GI1787428, Length=218, Percent_Identity=38.9908256880734, Blast_Score=162, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI17557057, Length=193, Percent_Identity=39.8963730569948, Blast_Score=152, Evalue=1e-37,
Organism=Saccharomyces cerevisiae, GI6324161, Length=230, Percent_Identity=30.8695652173913, Blast_Score=125, Evalue=5e-30,
Organism=Drosophila melanogaster, GI28571789, Length=209, Percent_Identity=36.8421052631579, Blast_Score=134, Evalue=6e-32,
Organism=Drosophila melanogaster, GI28572127, Length=215, Percent_Identity=34.4186046511628, Blast_Score=120, Evalue=9e-28,
Organism=Drosophila melanogaster, GI24663695, Length=215, Percent_Identity=26.5116279069767, Blast_Score=80, Evalue=8e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: NA

Molecular weight: Translated: 24907; Mature: 24776

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEFVFAPPAPVGVPVRGSNASFPVRRVYCVGRNYAAHAREMGSDPDREPPFFFCKPSDA
CCCEEECCCCCCCEEEECCCCCCCEEEEEEECCCHHHHHHHCCCCCCCCCCEEEECCCCC
VSYVADGTEGTFPYPPGTSNVHYEVELVVAIGKGGKDISVEQAASHVFGYAVGLDMTRRD
EEEEECCCCCCCCCCCCCCCEEEEEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCHHHHH
LQNESKKTGRPWETGKAFDRSAPIGPIVPVSAIGHPEKGEVTLSVNGAEKQRGDLSDLIW
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCEEEEEECCCCHHCCCHHHHHH
SVPEMVSYLSKLFELQPGDLIFSGTPEGVGPVVKGDVMQCHVGGVGDLTIKVV
HHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCEECCEEEEECCCCCCEEEEEC
>Mature Secondary Structure 
TEFVFAPPAPVGVPVRGSNASFPVRRVYCVGRNYAAHAREMGSDPDREPPFFFCKPSDA
CCEEECCCCCCCEEEECCCCCCCEEEEEEECCCHHHHHHHCCCCCCCCCCEEEECCCCC
VSYVADGTEGTFPYPPGTSNVHYEVELVVAIGKGGKDISVEQAASHVFGYAVGLDMTRRD
EEEEECCCCCCCCCCCCCCCEEEEEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCHHHHH
LQNESKKTGRPWETGKAFDRSAPIGPIVPVSAIGHPEKGEVTLSVNGAEKQRGDLSDLIW
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCEEEEEECCCCHHCCCHHHHHH
SVPEMVSYLSKLFELQPGDLIFSGTPEGVGPVVKGDVMQCHVGGVGDLTIKVV
HHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCEECCEEEEECCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12622808 [H]