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The map label for this gene is ampG [H]

Identifier: 73539897

GI number: 73539897

Start: 215485

End: 216744

Strand: Reverse

Name: ampG [H]

Synonym: Reut_A0191

Alternate gene names: 73539897

Gene position: 216744-215485 (Counterclockwise)

Preceding gene: 73539899

Following gene: 73539894

Centisome position: 5.69

GC content: 67.7

Gene sequence:

>1260_bases
ATGAATTTCCAGGACTATCTCGACATCTTCCGAAACCGCCGCATCGGCGCCATGCTGGCGCTGGGCTTCGCCTCAGGACT
GCCGCTGGCGCTCACGTCCGGCACGCTGCAGGCCTGGATGACGGTCGAAGGGCTCGATATCAAAACCATCGGCTTCTTCT
CGCTGGTGGGCCAGGCCTACATCTTCAAATTCCTGTGGGCGCCTCTGATGGACCGCTACACGCCGCCGCTGATGGGCCGG
CGCAAGGGCTGGCTGCTGGTCACGCAGATCGGGCTCGTGATCGGCATTGGCGCGATGGCATTCTGCCCGCCGCGCGAAGC
GCTGTGGACGCTGGCGGCGCTGGCTACGCTCGTGGCGTTCCTGTCGGCCTCGCAGGACATCGTGTTCGATGCCTACAGCA
CCGACGTGCTGCGCCCGGCCGAACGCGGCGCCGGCGCGGCCGTCAAGGTGCTCGGCTACCGGCTGGCGATGCTGGTCTCG
GGCGGTCTAGCGCTTTGGCTGGCAGACCGCGTGATGGGCTGGCCGCAGATGTACCTGCTGATGGCCGCGCTGATGGGCGT
CGGCATGGTCACGCTGCTGTGGGCGCCCGAGCCCGACGTGCCCGCGCGTGCGCCGCGCTCCCTCGAAGAAGCCATCGTCG
GCCCCCTGCGCGACTTCTTCTCGCGCCCCGGCGCATGGTGGCTGTTGCTGCTGATCGTGCTGTACAAGCTTGGCGACGCG
TTCGCCGGCAGCCTCTCCACGACGTTCCTGATCCGCGGTGTCGGCTTTTCCGCCGGCGAAGTCGGCATCGTCAACAAGAC
GCTCGGACTGGCCGCGACCATCGTCGGCGCGCTGTTCGGCGGCACGCTGATGGTGCGGCTCGGGCTGTATCGTTCCCTGA
TGCTGTTCGGCCTGCTGCAGGCCATATCCAACCTCGGCTACTGGATCCTGTCGGTGACGCCGCCGCACCTGTGGTCGATG
GGCGCCACCATCGCGGTCGAAAACCTCTGCGGCGGCATGGGCACGGCGGCGTTCGTCGCGCTGCTGATGACGCTGTGCAA
CCGCTCATTCTCGGCCACGCAGTACGCGCTGCTGTCGGCGCTGGCGTCGGTGGGCCGCGTCTACGTCGGACCGACCTCCG
GCTATATGGTCGAAGCCTGGGGCTGGGCGCCCTTCTACCTGGGCACGGTGCTGGTGGCATTGCCCGGCGTGCTGCTGCTC
TGGGCCATGCGCCACACCGTCCATCGCTACGAAGCCCAGGCGCGCGAAGCGATTGCCTGA

Upstream 100 bases:

>100_bases
AGGGAAAGCCGGGAGCAGTCTTGGACAGAGGGGGCAAACGGGTGATGCAATAATACACGGCGCCTGCGCAGCCGCGCGGC
GCCATCCGCCCACGCCATCC

Downstream 100 bases:

>100_bases
TCGGCGTAGCCGGCAGCCTTATTCCTTGTAGTAGACGATCTGGTGCGACGTGGCGAGCAACTCGCCACCCGCGCTCCAGA
CCTGCGCGCTTTGATCGAAA

Product: muropeptide transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 419; Mature: 419

Protein sequence:

>419_residues
MNFQDYLDIFRNRRIGAMLALGFASGLPLALTSGTLQAWMTVEGLDIKTIGFFSLVGQAYIFKFLWAPLMDRYTPPLMGR
RKGWLLVTQIGLVIGIGAMAFCPPREALWTLAALATLVAFLSASQDIVFDAYSTDVLRPAERGAGAAVKVLGYRLAMLVS
GGLALWLADRVMGWPQMYLLMAALMGVGMVTLLWAPEPDVPARAPRSLEEAIVGPLRDFFSRPGAWWLLLLIVLYKLGDA
FAGSLSTTFLIRGVGFSAGEVGIVNKTLGLAATIVGALFGGTLMVRLGLYRSLMLFGLLQAISNLGYWILSVTPPHLWSM
GATIAVENLCGGMGTAAFVALLMTLCNRSFSATQYALLSALASVGRVYVGPTSGYMVEAWGWAPFYLGTVLVALPGVLLL
WAMRHTVHRYEAQAREAIA

Sequences:

>Translated_419_residues
MNFQDYLDIFRNRRIGAMLALGFASGLPLALTSGTLQAWMTVEGLDIKTIGFFSLVGQAYIFKFLWAPLMDRYTPPLMGR
RKGWLLVTQIGLVIGIGAMAFCPPREALWTLAALATLVAFLSASQDIVFDAYSTDVLRPAERGAGAAVKVLGYRLAMLVS
GGLALWLADRVMGWPQMYLLMAALMGVGMVTLLWAPEPDVPARAPRSLEEAIVGPLRDFFSRPGAWWLLLLIVLYKLGDA
FAGSLSTTFLIRGVGFSAGEVGIVNKTLGLAATIVGALFGGTLMVRLGLYRSLMLFGLLQAISNLGYWILSVTPPHLWSM
GATIAVENLCGGMGTAAFVALLMTLCNRSFSATQYALLSALASVGRVYVGPTSGYMVEAWGWAPFYLGTVLVALPGVLLL
WAMRHTVHRYEAQAREAIA
>Mature_419_residues
MNFQDYLDIFRNRRIGAMLALGFASGLPLALTSGTLQAWMTVEGLDIKTIGFFSLVGQAYIFKFLWAPLMDRYTPPLMGR
RKGWLLVTQIGLVIGIGAMAFCPPREALWTLAALATLVAFLSASQDIVFDAYSTDVLRPAERGAGAAVKVLGYRLAMLVS
GGLALWLADRVMGWPQMYLLMAALMGVGMVTLLWAPEPDVPARAPRSLEEAIVGPLRDFFSRPGAWWLLLLIVLYKLGDA
FAGSLSTTFLIRGVGFSAGEVGIVNKTLGLAATIVGALFGGTLMVRLGLYRSLMLFGLLQAISNLGYWILSVTPPHLWSM
GATIAVENLCGGMGTAAFVALLMTLCNRSFSATQYALLSALASVGRVYVGPTSGYMVEAWGWAPFYLGTVLVALPGVLLL
WAMRHTVHRYEAQAREAIA

Specific function: Probably acts as a permease in the beta-lactamase induction system and in peptidoglycan recycling [H]

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily [H]

Homologues:

Organism=Homo sapiens, GI19923957, Length=364, Percent_Identity=29.6703296703297, Blast_Score=93, Evalue=5e-19,
Organism=Escherichia coli, GI1786636, Length=405, Percent_Identity=68.3950617283951, Blast_Score=543, Evalue=1e-156,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004752
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 45261; Mature: 45261

Theoretical pI: Translated: 9.54; Mature: 9.54

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFQDYLDIFRNRRIGAMLALGFASGLPLALTSGTLQAWMTVEGLDIKTIGFFSLVGQAY
CCHHHHHHHHHCCCHHHHHHHHHHCCCCEEEECCCCEEEEEECCCCEEHHHHHHHHHHHH
IFKFLWAPLMDRYTPPLMGRRKGWLLVTQIGLVIGIGAMAFCPPREALWTLAALATLVAF
HHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
LSASQDIVFDAYSTDVLRPAERGAGAAVKVLGYRLAMLVSGGLALWLADRVMGWPQMYLL
HHCCCCEEEECCCHHHHCHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHH
MAALMGVGMVTLLWAPEPDVPARAPRSLEEAIVGPLRDFFSRPGAWWLLLLIVLYKLGDA
HHHHHHHHHHHEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCHH
FAGSLSTTFLIRGVGFSAGEVGIVNKTLGLAATIVGALFGGTLMVRLGLYRSLMLFGLLQ
HHCCHHHHHHEEECCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AISNLGYWILSVTPPHLWSMGATIAVENLCGGMGTAAFVALLMTLCNRSFSATQYALLSA
HHHCCCEEEEEECCCHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHH
LASVGRVYVGPTSGYMVEAWGWAPFYLGTVLVALPGVLLLWAMRHTVHRYEAQAREAIA
HHHHCEEEECCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNFQDYLDIFRNRRIGAMLALGFASGLPLALTSGTLQAWMTVEGLDIKTIGFFSLVGQAY
CCHHHHHHHHHCCCHHHHHHHHHHCCCCEEEECCCCEEEEEECCCCEEHHHHHHHHHHHH
IFKFLWAPLMDRYTPPLMGRRKGWLLVTQIGLVIGIGAMAFCPPREALWTLAALATLVAF
HHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
LSASQDIVFDAYSTDVLRPAERGAGAAVKVLGYRLAMLVSGGLALWLADRVMGWPQMYLL
HHCCCCEEEECCCHHHHCHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHH
MAALMGVGMVTLLWAPEPDVPARAPRSLEEAIVGPLRDFFSRPGAWWLLLLIVLYKLGDA
HHHHHHHHHHHEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCHH
FAGSLSTTFLIRGVGFSAGEVGIVNKTLGLAATIVGALFGGTLMVRLGLYRSLMLFGLLQ
HHCCHHHHHHEEECCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AISNLGYWILSVTPPHLWSMGATIAVENLCGGMGTAAFVALLMTLCNRSFSATQYALLSA
HHHCCCEEEEEECCCHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHH
LASVGRVYVGPTSGYMVEAWGWAPFYLGTVLVALPGVLLLWAMRHTVHRYEAQAREAIA
HHHHCEEEECCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]