Click here to switch to the map view.

The map label for this gene is argC [H]

Identifier: 73539899

GI number: 73539899

Start: 217888

End: 218835

Strand: Reverse

Name: argC [H]

Synonym: Reut_A0193

Alternate gene names: 73539899

Gene position: 218835-217888 (Counterclockwise)

Preceding gene: 73539900

Following gene: 73539897

Centisome position: 5.75

GC content: 65.51

Gene sequence:

>948_bases
ATGGTTTTCAAAGTGTTCGTCGATGGTCAGGAAGGCACCACCGGTCTCCGGCTGCTTGACTATCTCTCTGGTCGTTCCGA
CGTCGAATTGCTGCGCATTGCTGATGACAAGCGCAAGGACCCGGCCGAGCGTGCACGCTTCCTGAATGCCGCAGACGTCG
CTTTCCTGTGCCTGCCGGACGTGGCCTCGCGCGAGGCCGTGTCGCTGGTGACCAACCCGAATACCTGCGTGATCGACGCC
AGCACCGCGTTCCGCACGTCAGACAGCTGGGCCTATGGCCTGCCGGAACTGGTGCGCGGCCAGCGCGAAAAGATCCGCGC
GAGCAAGCGCATCGCTGTGCCGGGCTGCCATGCCAGCGCCTTCGTGCTGGCGGTGCGTCCGCTGATCGATGCCGGCGTGC
TGCCGCGCGACTACCCGGTCTCGGCGTTCTCGCTGACCGGCTACAGCGGCGGCGGCAAGAAGATGATTGCCGACTTCGAA
GCCGGCGGTAATCCGAAGCTGCAAAGCCCGCGCCCGTACGCGCTTGGCCTGGCGCACAAGCACCTGCCCGAAATGCGCGT
GCAGGCCGGCCTGGCGGCGGAGCCTATCTTCAACCCGATCGTCGGCAACTTCTTCAAGGGCCTGGCCGTGACGGTGCCGG
TCTATGCTGACCGCCTCGCGCGCAAGGTCAGCCCCGAGCAGATCGTCGACATCTACCGCGAGCACTATGAAGGCGAGCAG
TTCGTGCGCGTGCTGCCGTACAACAGCGACGACAACCTCGACGATGGTTTCCTCGACGTGCAGGCCAACAACGACACCAA
CCGTGTCGACCTGTTCGTGTTCGGCACGCCCGATCGCCTGAATCTGGTCGCGCGCCTGGACAACCTGGGCAAGGGCGCGG
CCGGCGCGGCAGTGCAATGCATGAACGTGCATGTCGGCGCCGACGAGGCGACCGGGCTGCAGGCCTGA

Upstream 100 bases:

>100_bases
AAACCCCTGCGACCCGCCCCCATCCCCGTTACAATGCAGGTTCGCCCCTGCGCCCGGCAGGGACGTTTCGCATTCCCCGC
ATCTCTAGAGCGAGTCCGCC

Downstream 100 bases:

>100_bases
GCGTTTCAAGGTCTCAAGTAAAAAAGCCGGCATTGCCGGCTTTTTTACTTTCTGCGGGATCATCAGCGTTTGAGCGGCCG
CTGCCGGTCGTCGTCGCCGG

Product: N-acetyl-gamma-glutamyl-phosphate reductase

Products: NA

Alternate protein names: AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase [H]

Number of amino acids: Translated: 315; Mature: 315

Protein sequence:

>315_residues
MVFKVFVDGQEGTTGLRLLDYLSGRSDVELLRIADDKRKDPAERARFLNAADVAFLCLPDVASREAVSLVTNPNTCVIDA
STAFRTSDSWAYGLPELVRGQREKIRASKRIAVPGCHASAFVLAVRPLIDAGVLPRDYPVSAFSLTGYSGGGKKMIADFE
AGGNPKLQSPRPYALGLAHKHLPEMRVQAGLAAEPIFNPIVGNFFKGLAVTVPVYADRLARKVSPEQIVDIYREHYEGEQ
FVRVLPYNSDDNLDDGFLDVQANNDTNRVDLFVFGTPDRLNLVARLDNLGKGAAGAAVQCMNVHVGADEATGLQA

Sequences:

>Translated_315_residues
MVFKVFVDGQEGTTGLRLLDYLSGRSDVELLRIADDKRKDPAERARFLNAADVAFLCLPDVASREAVSLVTNPNTCVIDA
STAFRTSDSWAYGLPELVRGQREKIRASKRIAVPGCHASAFVLAVRPLIDAGVLPRDYPVSAFSLTGYSGGGKKMIADFE
AGGNPKLQSPRPYALGLAHKHLPEMRVQAGLAAEPIFNPIVGNFFKGLAVTVPVYADRLARKVSPEQIVDIYREHYEGEQ
FVRVLPYNSDDNLDDGFLDVQANNDTNRVDLFVFGTPDRLNLVARLDNLGKGAAGAAVQCMNVHVGADEATGLQA
>Mature_315_residues
MVFKVFVDGQEGTTGLRLLDYLSGRSDVELLRIADDKRKDPAERARFLNAADVAFLCLPDVASREAVSLVTNPNTCVIDA
STAFRTSDSWAYGLPELVRGQREKIRASKRIAVPGCHASAFVLAVRPLIDAGVLPRDYPVSAFSLTGYSGGGKKMIADFE
AGGNPKLQSPRPYALGLAHKHLPEMRVQAGLAAEPIFNPIVGNFFKGLAVTVPVYADRLARKVSPEQIVDIYREHYEGEQ
FVRVLPYNSDDNLDDGFLDVQANNDTNRVDLFVFGTPDRLNLVARLDNLGKGAAGAAVQCMNVHVGADEATGLQA

Specific function: Arginine biosynthesis; third step. [C]

COG id: COG0002

COG function: function code E; Acetylglutamate semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAGSA dehydrogenase family. Type 2 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790396, Length=303, Percent_Identity=30.03300330033, Blast_Score=87, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6320913, Length=306, Percent_Identity=30.0653594771242, Blast_Score=97, Evalue=5e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010136
- InterPro:   IPR016040
- InterPro:   IPR000534 [H]

Pfam domain/function: PF01118 Semialdhyde_dh [H]

EC number: =1.2.1.38 [H]

Molecular weight: Translated: 34175; Mature: 34175

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVFKVFVDGQEGTTGLRLLDYLSGRSDVELLRIADDKRKDPAERARFLNAADVAFLCLPD
CEEEEEEECCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHCCCCCEEEEECCC
VASREAVSLVTNPNTCVIDASTAFRTSDSWAYGLPELVRGQREKIRASKRIAVPGCHASA
CCCCCEEEEEECCCEEEEECCCCEECCCCCCCCCHHHHCCHHHHHHHHCEEECCCCCHHH
FVLAVRPLIDAGVLPRDYPVSAFSLTGYSGGGKKMIADFEAGGNPKLQSPRPYALGLAHK
HHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCEEEEEECCCCCCCCCCCCCCEECCHHH
HLPEMRVQAGLAAEPIFNPIVGNFFKGLAVTVPVYADRLARKVSPEQIVDIYREHYEGEQ
HCHHHHHHCCCCCCHHHHHHHHHHHCCCEEEEHHHHHHHHHHCCHHHHHHHHHHHCCCCE
FVRVLPYNSDDNLDDGFLDVQANNDTNRVDLFVFGTPDRLNLVARLDNLGKGAAGAAVQC
EEEEECCCCCCCCCCCEEEEEECCCCCEEEEEEEECCCHHHHHHHHHHCCCCCCCCEEEE
MNVHVGADEATGLQA
EEEEECCCCCCCCCC
>Mature Secondary Structure
MVFKVFVDGQEGTTGLRLLDYLSGRSDVELLRIADDKRKDPAERARFLNAADVAFLCLPD
CEEEEEEECCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHCCCCCEEEEECCC
VASREAVSLVTNPNTCVIDASTAFRTSDSWAYGLPELVRGQREKIRASKRIAVPGCHASA
CCCCCEEEEEECCCEEEEECCCCEECCCCCCCCCHHHHCCHHHHHHHHCEEECCCCCHHH
FVLAVRPLIDAGVLPRDYPVSAFSLTGYSGGGKKMIADFEAGGNPKLQSPRPYALGLAHK
HHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCEEEEEECCCCCCCCCCCCCCEECCHHH
HLPEMRVQAGLAAEPIFNPIVGNFFKGLAVTVPVYADRLARKVSPEQIVDIYREHYEGEQ
HCHHHHHHCCCCCCHHHHHHHHHHHCCCEEEEHHHHHHHHHHCCHHHHHHHHHHHCCCCE
FVRVLPYNSDDNLDDGFLDVQANNDTNRVDLFVFGTPDRLNLVARLDNLGKGAAGAAVQC
EEEEECCCCCCCCCCCEEEEEECCCCCEEEEEEEECCCHHHHHHHHHHCCCCCCCCEEEE
MNVHVGADEATGLQA
EEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]