Click here to switch to the map view.

The map label for this gene is creB [H]

Identifier: 73539891

GI number: 73539891

Start: 209836

End: 210516

Strand: Reverse

Name: creB [H]

Synonym: Reut_A0185

Alternate gene names: 73539891

Gene position: 210516-209836 (Counterclockwise)

Preceding gene: 73539894

Following gene: 73539890

Centisome position: 5.53

GC content: 66.96

Gene sequence:

>681_bases
ATGCACAAGCCGAACATCCTGGTCATCGAAGATGAATCCGCCATTGCCGACACGATCGACTATGCGCTGTCCACCGACGG
CATGGCCGTGGAGCGCTGCGCGCTCGGTGGCGATGCCCTGGAGCGGCTGCGCACGCAGGCATTCGACCTGGTGATCCTTG
ATGTCGGCCTGCCCGACCTGAGCGGCTTCGAGGTCTGCCGTACCCTGCGCACGTTCACCGATGTGCCGGTCATCTTCCTG
ACCGCGCGACATGATGAGATCGACCGCGTGGTCGGCCTGGAGATCGGCGCGGACGACTATGTGGTGAAGCCCTTCTCGCC
GCGCGAGCTGGCCGCGCGCGTGCGCGTGATCCTGCGGCGCACGGCGCGCCAGCCCGTTGCGGAACCCGCGAGCCAGAGCG
TATTCACGGTGGACAACGACGGCGCACGCGTGGCCTTCCACGGCCACTGGCTCGAACTCACGCGCTACGAGTACCGCATG
CTCGCGCTGATGCTGCGCCACCCTGGCCGCATCTATTCGCGCGCGCAGCTCATGGACGAGGTCTGGCACGACGCGCCGGA
CACGATCGACCGCACCGTCGATACCCACATCAAGACCGTGCGCGCCAAGCTGCGCGCACTCGATGCCGCCAGCGACCCGA
TCCGCACGCACCGCGGCATGGGCTACTCCATCGAACCATGA

Upstream 100 bases:

>100_bases
TCAAATCGGCGCGACGGCTTATTATAGTGCAATCCGCCGACCGCGCCGCATCGGGCGTTCATCCGCCACCCGCAAGCCAC
GTCGGCACCGCCGAATCGCC

Downstream 100 bases:

>100_bases
CGGTCGACCGGGCCTGAACATGCATATCGGGCTTCGCATCTTTTTCGGCTTCTTCGTGATCGTCGGGCTGGCCGCTTTCC
TCACGCTGCGCGTCTTTGTG

Product: DNA-binding response regulator CreB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MHKPNILVIEDESAIADTIDYALSTDGMAVERCALGGDALERLRTQAFDLVILDVGLPDLSGFEVCRTLRTFTDVPVIFL
TARHDEIDRVVGLEIGADDYVVKPFSPRELAARVRVILRRTARQPVAEPASQSVFTVDNDGARVAFHGHWLELTRYEYRM
LALMLRHPGRIYSRAQLMDEVWHDAPDTIDRTVDTHIKTVRAKLRALDAASDPIRTHRGMGYSIEP

Sequences:

>Translated_226_residues
MHKPNILVIEDESAIADTIDYALSTDGMAVERCALGGDALERLRTQAFDLVILDVGLPDLSGFEVCRTLRTFTDVPVIFL
TARHDEIDRVVGLEIGADDYVVKPFSPRELAARVRVILRRTARQPVAEPASQSVFTVDNDGARVAFHGHWLELTRYEYRM
LALMLRHPGRIYSRAQLMDEVWHDAPDTIDRTVDTHIKTVRAKLRALDAASDPIRTHRGMGYSIEP
>Mature_226_residues
MHKPNILVIEDESAIADTIDYALSTDGMAVERCALGGDALERLRTQAFDLVILDVGLPDLSGFEVCRTLRTFTDVPVIFL
TARHDEIDRVVGLEIGADDYVVKPFSPRELAARVRVILRRTARQPVAEPASQSVFTVDNDGARVAFHGHWLELTRYEYRM
LALMLRHPGRIYSRAQLMDEVWHDAPDTIDRTVDTHIKTVRAKLRALDAASDPIRTHRGMGYSIEP

Specific function: Member of the two-component regulatory system CreC/CreB involved in catabolic regulation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790860, Length=226, Percent_Identity=53.0973451327434, Blast_Score=240, Evalue=7e-65,
Organism=Escherichia coli, GI1788394, Length=225, Percent_Identity=39.1111111111111, Blast_Score=173, Evalue=1e-44,
Organism=Escherichia coli, GI1786599, Length=220, Percent_Identity=37.7272727272727, Blast_Score=144, Evalue=6e-36,
Organism=Escherichia coli, GI1790863, Length=230, Percent_Identity=33.4782608695652, Blast_Score=134, Evalue=6e-33,
Organism=Escherichia coli, GI1786911, Length=222, Percent_Identity=38.7387387387387, Blast_Score=131, Evalue=3e-32,
Organism=Escherichia coli, GI1786784, Length=222, Percent_Identity=34.6846846846847, Blast_Score=128, Evalue=3e-31,
Organism=Escherichia coli, GI1789809, Length=230, Percent_Identity=35.2173913043478, Blast_Score=127, Evalue=4e-31,
Organism=Escherichia coli, GI1787229, Length=225, Percent_Identity=36.4444444444444, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI87082012, Length=224, Percent_Identity=37.0535714285714, Blast_Score=120, Evalue=5e-29,
Organism=Escherichia coli, GI1789402, Length=221, Percent_Identity=36.1990950226244, Blast_Score=119, Evalue=1e-28,
Organism=Escherichia coli, GI2367329, Length=224, Percent_Identity=37.9464285714286, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1790552, Length=222, Percent_Identity=33.7837837837838, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1787375, Length=224, Percent_Identity=30.8035714285714, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI145693140, Length=235, Percent_Identity=28.0851063829787, Blast_Score=86, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25447; Mature: 25447

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00213 LIPOCALIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHKPNILVIEDESAIADTIDYALSTDGMAVERCALGGDALERLRTQAFDLVILDVGLPDL
CCCCCEEEEECCCHHHHHHHHHHCCCCCHHHHHHCCHHHHHHHHHHHHEEEEEECCCCCC
SGFEVCRTLRTFTDVPVIFLTARHDEIDRVVGLEIGADDYVVKPFSPRELAARVRVILRR
CHHHHHHHHHHHCCCCEEEEEECCCCHHHEEEEEECCCCEEECCCCHHHHHHHHHHHHHH
TARQPVAEPASQSVFTVDNDGARVAFHGHWLELTRYEYRMLALMLRHPGRIYSRAQLMDE
HHCCCCCCCCCCCEEEEECCCCEEEEECCEEEHHHHHHHHHHHHHHCCCHHHHHHHHHHH
VWHDAPDTIDRTVDTHIKTVRAKLRALDAASDPIRTHRGMGYSIEP
HHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCC
>Mature Secondary Structure
MHKPNILVIEDESAIADTIDYALSTDGMAVERCALGGDALERLRTQAFDLVILDVGLPDL
CCCCCEEEEECCCHHHHHHHHHHCCCCCHHHHHHCCHHHHHHHHHHHHEEEEEECCCCCC
SGFEVCRTLRTFTDVPVIFLTARHDEIDRVVGLEIGADDYVVKPFSPRELAARVRVILRR
CHHHHHHHHHHHCCCCEEEEEECCCCHHHEEEEEECCCCEEECCCCHHHHHHHHHHHHHH
TARQPVAEPASQSVFTVDNDGARVAFHGHWLELTRYEYRMLALMLRHPGRIYSRAQLMDE
HHCCCCCCCCCCCEEEEECCCCEEEEECCEEEHHHHHHHHHHHHHHCCCHHHHHHHHHHH
VWHDAPDTIDRTVDTHIKTVRAKLRALDAASDPIRTHRGMGYSIEP
HHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3531171; 7610040; 9278503 [H]