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The map label for this gene is tcp [H]

Identifier: 73539419

GI number: 73539419

Start: 2414330

End: 2416042

Strand: Direct

Name: tcp [H]

Synonym: Reut_B5597

Alternate gene names: 73539419

Gene position: 2414330-2416042 (Clockwise)

Preceding gene: 73539417

Following gene: 73539420

Centisome position: 88.56

GC content: 65.15

Gene sequence:

>1713_bases
ATGTCATTTGAGAACAATATCCAGATCAAGACCCTGTTAAGGGGCGCCATGGCCACGCTGTCGTTGCTGCTCATCCTGAT
GGGGGGCGCGGGGCTGCACGGAATCTCTCAGAGCAATGACGCATTGAAGGAAACGTATTCGAACCAGCTTGCCTCGACGA
TGGCGCTGAGCGACGCCATGCTGGCCACGGTCCGCATGCGCCTGGCGCTCGACCGCAACGTTATGCAGGGCGAACTGGAC
GATCCCAGGGTCAACGTCGACCGCTCCAGGGTCTTCGTCGAAGCCTCGGATTCGGCCTGGAAGCGCTATGCGAGCCTGCC
GCAGAACGACCAGGAGAAGGCGCTCGCCGATGAACTCGCACGCAAGCGCGCCGACTTCATGACGCATGGCATCGAGCCGT
TGCAGAAGGCTTCACTGGCCGGAAACCAGGAAGAGGCGGTTAGGCTGGCCAGCAAGGTCTTGCCCGAACTGCAGCGTGCC
ATGTCTTCAGCGCATGAGGCGCTGCAGAAATTCCAGCTGACCGCCGGCCAGGACAACTTCGACGCGGCGCAGGCTCGTTT
CGAGCGGATCCGCATTCTGTCGATCGTGCTGATCGTCGCCGGGCTTGCCATCGCGGCGCTGTGCACGGTGACGCTGAACC
GCGCCATCGTGCGCCCGGTCCAGGAAGCGCTGACGGTGATGGAGCGGATCGCGCGCGGCGACCTGACCTCGCGCATCAGC
ACGGTGTCCCGCAACGAAGTCGGACGCATGATGCAGGCGCTGGCGGCCATGCAGGACAGCCTTCAAAAGATCGTGTCGGA
GGTCCGTGTCGGCGCCGACTCCATGGCGTCGGCGACCGAACAGATCTCCAGCGGCAACCTGGACCTGTCCCAACGCACGG
AAGAGCAGGCTTCCTCGCTCGAGGAAACTGCGGCCAGCATGGAAGAACTGACGACCGTGGTGCGCCAGAACGCAGACAAT
GCCCGCCAGGCCGGCATACTGGCTGGCGAGGCTTCGCAGATCGCCGTCAAGGGTGGAGACGTGGTCGGCCGCGTGGTCGA
CACCATGAACGAGATCAACGACGCGTCGCGCAAGGTGGTCGAGATCATCAGCGTGATCGAAGGCATCGCGTTCCAGACGA
ATATCCTCGCGCTCAATGCCGCGGTCGAAGCGGCCCGCGCGGGCGAGCAAGGGCGGGGCTTTGCGGTGGTCGCGGGCGAA
GTGCGCAGCCTGGCGCAGCGCTCGGCGACCGCGGCCAAGGAAATCGAGGCGCTGATCAGTGAATCCGGCCAGCGCGTGGA
AAGCGGGACGCGCCTGGTGGCGGAGGCGGGCCAGACCATGGGCGAGATCGTGCAGGCTGTGCGCCGGGTCACGGACATCA
TGAACGAGATTGGTGCTGCCTCGCAGGAGCAGACCAGCGGTATCGAACAGGTGAACCAGGCCGTCACCCAGATGGACCAG
GTCACGCAGCAGAATGCCGCGCTGGTCGAAGAGGCGGCCGCGGCCGCCGGTTCGCTGGAAGAACAGGCTCGCAAGCTCAA
GAGCGTGGTTTCGGTATTCAATGTAGGCGGCGGAGCCGGTACAGTTGCGCAGGTCGCCGTACGCACGCCACAGGCCAAGC
CGGTCAGGCCGCGCGCGGCGGCAACGCTGGCCCGCTCGTCCGTCACGGTACGTCCTGTCCGCGCGGTTGCGGCGGTACAG
CGTGGCGCGGACGACGACTGGAGCGCTTTCTAG

Upstream 100 bases:

>100_bases
TGTGCAAGCCGTTATCCGGGCAGGGCGGATCGTCGGGGTGTCGGTTCGCCGTACCGGGACCAAGGGTGTGTCCTGCGGAT
TGCCTACCGTCGCATTCATC

Downstream 100 bases:

>100_bases
CACGGATGAAGTATTGCCTTGTTCACAGAGCGACCGCAAAGTGCCATGATTCGGGGTTTGCCTCGGATTGCCCGACTGTT
CGCGCATTCTTCTAATTTCC

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: Citrate chemoreceptor protein [H]

Number of amino acids: Translated: 570; Mature: 569

Protein sequence:

>570_residues
MSFENNIQIKTLLRGAMATLSLLLILMGGAGLHGISQSNDALKETYSNQLASTMALSDAMLATVRMRLALDRNVMQGELD
DPRVNVDRSRVFVEASDSAWKRYASLPQNDQEKALADELARKRADFMTHGIEPLQKASLAGNQEEAVRLASKVLPELQRA
MSSAHEALQKFQLTAGQDNFDAAQARFERIRILSIVLIVAGLAIAALCTVTLNRAIVRPVQEALTVMERIARGDLTSRIS
TVSRNEVGRMMQALAAMQDSLQKIVSEVRVGADSMASATEQISSGNLDLSQRTEEQASSLEETAASMEELTTVVRQNADN
ARQAGILAGEASQIAVKGGDVVGRVVDTMNEINDASRKVVEIISVIEGIAFQTNILALNAAVEAARAGEQGRGFAVVAGE
VRSLAQRSATAAKEIEALISESGQRVESGTRLVAEAGQTMGEIVQAVRRVTDIMNEIGAASQEQTSGIEQVNQAVTQMDQ
VTQQNAALVEEAAAAAGSLEEQARKLKSVVSVFNVGGGAGTVAQVAVRTPQAKPVRPRAAATLARSSVTVRPVRAVAAVQ
RGADDDWSAF

Sequences:

>Translated_570_residues
MSFENNIQIKTLLRGAMATLSLLLILMGGAGLHGISQSNDALKETYSNQLASTMALSDAMLATVRMRLALDRNVMQGELD
DPRVNVDRSRVFVEASDSAWKRYASLPQNDQEKALADELARKRADFMTHGIEPLQKASLAGNQEEAVRLASKVLPELQRA
MSSAHEALQKFQLTAGQDNFDAAQARFERIRILSIVLIVAGLAIAALCTVTLNRAIVRPVQEALTVMERIARGDLTSRIS
TVSRNEVGRMMQALAAMQDSLQKIVSEVRVGADSMASATEQISSGNLDLSQRTEEQASSLEETAASMEELTTVVRQNADN
ARQAGILAGEASQIAVKGGDVVGRVVDTMNEINDASRKVVEIISVIEGIAFQTNILALNAAVEAARAGEQGRGFAVVAGE
VRSLAQRSATAAKEIEALISESGQRVESGTRLVAEAGQTMGEIVQAVRRVTDIMNEIGAASQEQTSGIEQVNQAVTQMDQ
VTQQNAALVEEAAAAAGSLEEQARKLKSVVSVFNVGGGAGTVAQVAVRTPQAKPVRPRAAATLARSSVTVRPVRAVAAVQ
RGADDDWSAF
>Mature_569_residues
SFENNIQIKTLLRGAMATLSLLLILMGGAGLHGISQSNDALKETYSNQLASTMALSDAMLATVRMRLALDRNVMQGELDD
PRVNVDRSRVFVEASDSAWKRYASLPQNDQEKALADELARKRADFMTHGIEPLQKASLAGNQEEAVRLASKVLPELQRAM
SSAHEALQKFQLTAGQDNFDAAQARFERIRILSIVLIVAGLAIAALCTVTLNRAIVRPVQEALTVMERIARGDLTSRIST
VSRNEVGRMMQALAAMQDSLQKIVSEVRVGADSMASATEQISSGNLDLSQRTEEQASSLEETAASMEELTTVVRQNADNA
RQAGILAGEASQIAVKGGDVVGRVVDTMNEINDASRKVVEIISVIEGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEV
RSLAQRSATAAKEIEALISESGQRVESGTRLVAEAGQTMGEIVQAVRRVTDIMNEIGAASQEQTSGIEQVNQAVTQMDQV
TQQNAALVEEAAAAAGSLEEQARKLKSVVSVFNVGGGAGTVAQVAVRTPQAKPVRPRAAATLARSSVTVRPVRAVAAVQR
GADDDWSAF

Specific function: Acts as a receptor for citrate and mediates taxis away from phenol. Also mediates an attractant response to metal-citrate complexes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=439, Percent_Identity=47.1526195899772, Blast_Score=335, Evalue=4e-93,
Organism=Escherichia coli, GI1788195, Length=552, Percent_Identity=42.5724637681159, Blast_Score=315, Evalue=6e-87,
Organism=Escherichia coli, GI2367378, Length=523, Percent_Identity=41.6826003824092, Blast_Score=305, Evalue=5e-84,
Organism=Escherichia coli, GI1788194, Length=536, Percent_Identity=41.6044776119403, Blast_Score=303, Evalue=2e-83,
Organism=Escherichia coli, GI1789453, Length=426, Percent_Identity=33.8028169014084, Blast_Score=209, Evalue=5e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 60698; Mature: 60566

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFENNIQIKTLLRGAMATLSLLLILMGGAGLHGISQSNDALKETYSNQLASTMALSDAM
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LATVRMRLALDRNVMQGELDDPRVNVDRSRVFVEASDSAWKRYASLPQNDQEKALADELA
HHHHHHHHHHHHHHHCCCCCCCCCCCCHHEEEEECCHHHHHHHHCCCCCCHHHHHHHHHH
RKRADFMTHGIEPLQKASLAGNQEEAVRLASKVLPELQRAMSSAHEALQKFQLTAGQDNF
HHHHHHHHHCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
DAAQARFERIRILSIVLIVAGLAIAALCTVTLNRAIVRPVQEALTVMERIARGDLTSRIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHH
TVSRNEVGRMMQALAAMQDSLQKIVSEVRVGADSMASATEQISSGNLDLSQRTEEQASSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
EETAASMEELTTVVRQNADNARQAGILAGEASQIAVKGGDVVGRVVDTMNEINDASRKVV
HHHHHHHHHHHHHHHHCCCCHHHCCCEECCCCEEEECCCHHHHHHHHHHHHHHHHHHHHH
EIISVIEGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRSLAQRSATAAKEIEALIS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHH
ESGQRVESGTRLVAEAGQTMGEIVQAVRRVTDIMNEIGAASQEQTSGIEQVNQAVTQMDQ
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
VTQQNAALVEEAAAAAGSLEEQARKLKSVVSVFNVGGGAGTVAQVAVRTPQAKPVRPRAA
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCHHH
ATLARSSVTVRPVRAVAAVQRGADDDWSAF
HHHHHCCCCHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
SFENNIQIKTLLRGAMATLSLLLILMGGAGLHGISQSNDALKETYSNQLASTMALSDAM
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LATVRMRLALDRNVMQGELDDPRVNVDRSRVFVEASDSAWKRYASLPQNDQEKALADELA
HHHHHHHHHHHHHHHCCCCCCCCCCCCHHEEEEECCHHHHHHHHCCCCCCHHHHHHHHHH
RKRADFMTHGIEPLQKASLAGNQEEAVRLASKVLPELQRAMSSAHEALQKFQLTAGQDNF
HHHHHHHHHCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
DAAQARFERIRILSIVLIVAGLAIAALCTVTLNRAIVRPVQEALTVMERIARGDLTSRIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHH
TVSRNEVGRMMQALAAMQDSLQKIVSEVRVGADSMASATEQISSGNLDLSQRTEEQASSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
EETAASMEELTTVVRQNADNARQAGILAGEASQIAVKGGDVVGRVVDTMNEINDASRKVV
HHHHHHHHHHHHHHHHCCCCHHHCCCEECCCCEEEECCCHHHHHHHHHHHHHHHHHHHHH
EIISVIEGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRSLAQRSATAAKEIEALIS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHH
ESGQRVESGTRLVAEAGQTMGEIVQAVRRVTDIMNEIGAASQEQTSGIEQVNQAVTQMDQ
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
VTQQNAALVEEAAAAAGSLEEQARKLKSVVSVFNVGGGAGTVAQVAVRTPQAKPVRPRAA
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCHHH
ATLARSSVTVRPVRAVAAVQRGADDDWSAF
HHHHHCCCCHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8419927; 11677609 [H]