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The map label for this gene is galE [H]

Identifier: 73539417

GI number: 73539417

Start: 2412356

End: 2413375

Strand: Direct

Name: galE [H]

Synonym: Reut_B5595

Alternate gene names: 73539417

Gene position: 2412356-2413375 (Clockwise)

Preceding gene: 73539416

Following gene: 73539419

Centisome position: 88.49

GC content: 61.96

Gene sequence:

>1020_bases
ATGTCCCAGACCTTGCTGCTTACCGGTGCTACCGGCTATATCGCTTCCCATACCTGGGTCGCATTGCTCAATGCCGGCTA
CAAGGTGATCGGGCTCGATAATCTGTGCAATAGCAGCCGCGTGGTGGTAGACCGGCTGGCAACCATTACCGGGCAGACTC
CGCATTTTGTCGAGGGCGATGTCCGCGACCGCGCGCTGCTGGACCGCCTGTTCGCCGAACATGACATCACCGGCGCAATC
CATTTTGCTGCGCTCAAGGCGGTAGGGGAATCCGTCAGCCAGCCGCTCGAGTATTACAGCAACAACCTGGACGGCATGCT
TACGCTATGCGCGGCCATGCGCGACGCCGGGGTAAAACAACTGGTGTTCAGTTCGTCAGCCACTGTCTACGGCAATCCGC
ATGCGGTGCCCATTCTCGAGGATTTCCCGTTGTCGGCCACCAACCCCTATGGCCAGACCAAGCTGATGGGCGAGCAAATC
CTGCGCGATCTCGAAAAATCGGATCCCGAGTGGCGCATTGCCTACCTTCGGTATTTCAACCCGGTTGGCGCGCATAAAAG
CGGGCTGATCGGCGAAGACCCGCGCGGGATCCCGAATAACCTCATGCCTTATGTCGCGCAGGTGGCTGGCGGCCGCCGTG
AAAAGCTCATGGTATTCGGCGGCGACTATCCGACGCCGGACGGCACCGGCGTACGCGATTACATCCACGTCTGCGACCTT
GCTGATGGCCATCTGGCCGCGCTGGTCTGTTTGCGCGACCGCGGTCAGAGCATGACGGTCAACCTTGGCACGGGCAGTGG
CTACAGCGTGCTGGAGGTCGTGGCGGCGTACCAGAGGGCGAGCGGACGCCCAGTGCCTTACGAGATCGTGGCGCGCCGCC
CCGGCGATATTGCATCGTGCTATGCCGATCCCGCGCTGGCGCACCAGTTGCTGGGCTGGCGCGCGCGTCACGGCCTTGAT
CGCATGTGCGAGGATTCGTGGCGCTGGCAGTCCACCAACCCCAATGGTTTTGACGCCTGA

Upstream 100 bases:

>100_bases
TGGTTGTTCCGGCGTGTGCTGTGCTGCACACAACGCGCTGAGTCGGCCCTCCGATGGTCGATGTTCGCCCATCGTTTTTC
TGATTGATTACTGAATTTCC

Downstream 100 bases:

>100_bases
AATCTGGGGCGTACCCGTTTCTGCGTTGCCGCGGTTTGCGGCAAACGCTGAGAAAACAAAAACGCCACGGAGGTTTCCGT
GGCGTTTTGCTTTGGCAGAA

Product: UDP-galactose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 339; Mature: 338

Protein sequence:

>339_residues
MSQTLLLTGATGYIASHTWVALLNAGYKVIGLDNLCNSSRVVVDRLATITGQTPHFVEGDVRDRALLDRLFAEHDITGAI
HFAALKAVGESVSQPLEYYSNNLDGMLTLCAAMRDAGVKQLVFSSSATVYGNPHAVPILEDFPLSATNPYGQTKLMGEQI
LRDLEKSDPEWRIAYLRYFNPVGAHKSGLIGEDPRGIPNNLMPYVAQVAGGRREKLMVFGGDYPTPDGTGVRDYIHVCDL
ADGHLAALVCLRDRGQSMTVNLGTGSGYSVLEVVAAYQRASGRPVPYEIVARRPGDIASCYADPALAHQLLGWRARHGLD
RMCEDSWRWQSTNPNGFDA

Sequences:

>Translated_339_residues
MSQTLLLTGATGYIASHTWVALLNAGYKVIGLDNLCNSSRVVVDRLATITGQTPHFVEGDVRDRALLDRLFAEHDITGAI
HFAALKAVGESVSQPLEYYSNNLDGMLTLCAAMRDAGVKQLVFSSSATVYGNPHAVPILEDFPLSATNPYGQTKLMGEQI
LRDLEKSDPEWRIAYLRYFNPVGAHKSGLIGEDPRGIPNNLMPYVAQVAGGRREKLMVFGGDYPTPDGTGVRDYIHVCDL
ADGHLAALVCLRDRGQSMTVNLGTGSGYSVLEVVAAYQRASGRPVPYEIVARRPGDIASCYADPALAHQLLGWRARHGLD
RMCEDSWRWQSTNPNGFDA
>Mature_338_residues
SQTLLLTGATGYIASHTWVALLNAGYKVIGLDNLCNSSRVVVDRLATITGQTPHFVEGDVRDRALLDRLFAEHDITGAIH
FAALKAVGESVSQPLEYYSNNLDGMLTLCAAMRDAGVKQLVFSSSATVYGNPHAVPILEDFPLSATNPYGQTKLMGEQIL
RDLEKSDPEWRIAYLRYFNPVGAHKSGLIGEDPRGIPNNLMPYVAQVAGGRREKLMVFGGDYPTPDGTGVRDYIHVCDLA
DGHLAALVCLRDRGQSMTVNLGTGSGYSVLEVVAAYQRASGRPVPYEIVARRPGDIASCYADPALAHQLLGWRARHGLDR
MCEDSWRWQSTNPNGFDA

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=344, Percent_Identity=55.8139534883721, Blast_Score=393, Evalue=1e-109,
Organism=Homo sapiens, GI56118217, Length=344, Percent_Identity=55.8139534883721, Blast_Score=393, Evalue=1e-109,
Organism=Homo sapiens, GI189083684, Length=344, Percent_Identity=55.8139534883721, Blast_Score=393, Evalue=1e-109,
Organism=Homo sapiens, GI7657641, Length=278, Percent_Identity=26.978417266187, Blast_Score=86, Evalue=5e-17,
Organism=Escherichia coli, GI1786974, Length=334, Percent_Identity=56.2874251497006, Blast_Score=387, Evalue=1e-109,
Organism=Escherichia coli, GI48994969, Length=358, Percent_Identity=24.0223463687151, Blast_Score=65, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI71982035, Length=345, Percent_Identity=53.9130434782609, Blast_Score=369, Evalue=1e-102,
Organism=Caenorhabditis elegans, GI71982038, Length=347, Percent_Identity=53.8904899135447, Blast_Score=368, Evalue=1e-102,
Organism=Saccharomyces cerevisiae, GI6319493, Length=345, Percent_Identity=50.1449275362319, Blast_Score=335, Evalue=8e-93,
Organism=Drosophila melanogaster, GI19923002, Length=343, Percent_Identity=55.3935860058309, Blast_Score=389, Evalue=1e-108,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040
- InterPro:   IPR008089 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 36952; Mature: 36821

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQTLLLTGATGYIASHTWVALLNAGYKVIGLDNLCNSSRVVVDRLATITGQTPHFVEGD
CCCEEEEECCCCHHHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHHCCCCCCCCCCC
VRDRALLDRLFAEHDITGAIHFAALKAVGESVSQPLEYYSNNLDGMLTLCAAMRDAGVKQ
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHH
LVFSSSATVYGNPHAVPILEDFPLSATNPYGQTKLMGEQILRDLEKSDPEWRIAYLRYFN
HHHCCCCEECCCCCEECEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCC
PVGAHKSGLIGEDPRGIPNNLMPYVAQVAGGRREKLMVFGGDYPTPDGTGVRDYIHVCDL
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCHHHHHHHHCC
ADGHLAALVCLRDRGQSMTVNLGTGSGYSVLEVVAAYQRASGRPVPYEIVARRPGDIASC
CCCHHHHHEEECCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCCHHEEECCCCCHHHH
YADPALAHQLLGWRARHGLDRMCEDSWRWQSTNPNGFDA
HCCHHHHHHHHHHHHHHCHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SQTLLLTGATGYIASHTWVALLNAGYKVIGLDNLCNSSRVVVDRLATITGQTPHFVEGD
CCEEEEECCCCHHHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHHCCCCCCCCCCC
VRDRALLDRLFAEHDITGAIHFAALKAVGESVSQPLEYYSNNLDGMLTLCAAMRDAGVKQ
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHH
LVFSSSATVYGNPHAVPILEDFPLSATNPYGQTKLMGEQILRDLEKSDPEWRIAYLRYFN
HHHCCCCEECCCCCEECEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCC
PVGAHKSGLIGEDPRGIPNNLMPYVAQVAGGRREKLMVFGGDYPTPDGTGVRDYIHVCDL
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCHHHHHHHHCC
ADGHLAALVCLRDRGQSMTVNLGTGSGYSVLEVVAAYQRASGRPVPYEIVARRPGDIASC
CCCHHHHHEEECCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCCHHEEECCCCCHHHH
YADPALAHQLLGWRARHGLDRMCEDSWRWQSTNPNGFDA
HCCHHHHHHHHHHHHHHCHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8978088; 8969509; 9384377 [H]