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The map label for this gene is pgl [H]

Identifier: 73539150

GI number: 73539150

Start: 2093305

End: 2093985

Strand: Reverse

Name: pgl [H]

Synonym: Reut_B5328

Alternate gene names: 73539150

Gene position: 2093985-2093305 (Counterclockwise)

Preceding gene: 73539151

Following gene: 73539149

Centisome position: 76.81

GC content: 69.46

Gene sequence:

>681_bases
ATGCGCGAATTCGAGCATGCAAACGCGATGGACCAGGCCGAGGCGCTGGCCATTTCCATCGGCAATGCACTGGACCAGGC
GATCCGCGTCAACGGCTGGGCCGTGCTCGCGGTGTCCGGCAGCCGCTCGCCGGTGCCGATGTTCGAGCGCCTGCGCTACC
GCCCCGTGCGCTGGGACGCAGTGACCATCACGCTGGTCGACGAGCGCGTGGTGCCGCCGGACCACCCCGACAGCAATGGC
GGGCTCGTGCGCGCACACCTGCTGCGCGAAGCCGCGGCCAGTGCGGCGTTCGTGCCGCTGATCGCGGATGCCGCTGAGGT
CGCGGACCCGGCGAGCGCCGTGGCGCGGCTCAACAAGGCATTCCGGCAACCCGACGTCGTGGTGCTCGGCATGGGCGAGG
ATGGGCACACCGCATCGCTGTTCCCGGATGCGCCCGAACTGCAGACCGCACTCAGCGACCCGAAGCCCGGGTACCTCATT
ACCCATCCGTCGAGCGCGCCGCATGTGCGCGTGACGCTGAACCTTGCCGCGATCCTCGCTGCCGAGCGTGCTTTCCTTGC
TGTCGCAGGCAAGGTCAAGGCCGAGGTGCTGGCCCGCGCAATGCAAGGCCCGACGCCGGCGCTGCCGGTCAGCATCGTGC
TGGCCAACCAGCGCCGCGGCTTCGACCTTTTCCGTGCATGA

Upstream 100 bases:

>100_bases
AGCCGTATACCGCGGGCACGTGGGGTCCGGCGGCGTCGTCGGCGCTGATGTCGCGCGACGACTCGCTGTGGCACGAGGAA
GCCTGACTGGAGATACCGCC

Downstream 100 bases:

>100_bases
GCAACGCCATGGCTGCTTCCGCCGTGCCCGATGACACCGCCTATCCGCGTTTGCTGGCCGACGTGGGCGGGACCAATGTG
CGCTTCGCACTGGAAACGGC

Product: 6-phosphogluconolactonase

Products: NA

Alternate protein names: 6PGL [H]

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MREFEHANAMDQAEALAISIGNALDQAIRVNGWAVLAVSGSRSPVPMFERLRYRPVRWDAVTITLVDERVVPPDHPDSNG
GLVRAHLLREAAASAAFVPLIADAAEVADPASAVARLNKAFRQPDVVVLGMGEDGHTASLFPDAPELQTALSDPKPGYLI
THPSSAPHVRVTLNLAAILAAERAFLAVAGKVKAEVLARAMQGPTPALPVSIVLANQRRGFDLFRA

Sequences:

>Translated_226_residues
MREFEHANAMDQAEALAISIGNALDQAIRVNGWAVLAVSGSRSPVPMFERLRYRPVRWDAVTITLVDERVVPPDHPDSNG
GLVRAHLLREAAASAAFVPLIADAAEVADPASAVARLNKAFRQPDVVVLGMGEDGHTASLFPDAPELQTALSDPKPGYLI
THPSSAPHVRVTLNLAAILAAERAFLAVAGKVKAEVLARAMQGPTPALPVSIVLANQRRGFDLFRA
>Mature_226_residues
MREFEHANAMDQAEALAISIGNALDQAIRVNGWAVLAVSGSRSPVPMFERLRYRPVRWDAVTITLVDERVVPPDHPDSNG
GLVRAHLLREAAASAAFVPLIADAAEVADPASAVARLNKAFRQPDVVVLGMGEDGHTASLFPDAPELQTALSDPKPGYLI
THPSSAPHVRVTLNLAAILAAERAFLAVAGKVKAEVLARAMQGPTPALPVSIVLANQRRGFDLFRA

Specific function: Hydrolysis of 6-phosphogluconolactone to 6- phosphogluconate [H]

COG id: COG0363

COG function: function code G; 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily [H]

Homologues:

Organism=Homo sapiens, GI52145310, Length=223, Percent_Identity=34.5291479820628, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI6912586, Length=152, Percent_Identity=37.5, Blast_Score=77, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6324362, Length=178, Percent_Identity=30.8988764044944, Blast_Score=68, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6319918, Length=178, Percent_Identity=29.2134831460674, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005900 [H]

Pfam domain/function: NA

EC number: =3.1.1.31 [H]

Molecular weight: Translated: 24069; Mature: 24069

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREFEHANAMDQAEALAISIGNALDQAIRVNGWAVLAVSGSRSPVPMFERLRYRPVRWDA
CCCCCCCCCHHHHHHHEEEHHHHHHHHEEECCEEEEEECCCCCCCCHHHHHCCCCCEEEE
VTITLVDERVVPPDHPDSNGGLVRAHLLREAAASAAFVPLIADAAEVADPASAVARLNKA
EEEEEECCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
FRQPDVVVLGMGEDGHTASLFPDAPELQTALSDPKPGYLITHPSSAPHVRVTLNLAAILA
HCCCCEEEEEECCCCCEEEECCCCHHHHHHHCCCCCCEEEECCCCCCEEEEEEEHHHHHH
AERAFLAVAGKVKAEVLARAMQGPTPALPVSIVLANQRRGFDLFRA
HHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHCC
>Mature Secondary Structure
MREFEHANAMDQAEALAISIGNALDQAIRVNGWAVLAVSGSRSPVPMFERLRYRPVRWDA
CCCCCCCCCHHHHHHHEEEHHHHHHHHEEECCEEEEEECCCCCCCCHHHHHCCCCCEEEE
VTITLVDERVVPPDHPDSNGGLVRAHLLREAAASAAFVPLIADAAEVADPASAVARLNKA
EEEEEECCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
FRQPDVVVLGMGEDGHTASLFPDAPELQTALSDPKPGYLITHPSSAPHVRVTLNLAAILA
HCCCCEEEEEECCCCCEEEECCCCHHHHHHHCCCCCCEEEECCCCCCEEEEEEEHHHHHH
AERAFLAVAGKVKAEVLARAMQGPTPALPVSIVLANQRRGFDLFRA
HHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]