Click here to switch to the map view.

The map label for this gene is sdaA [H]

Identifier: 73538632

GI number: 73538632

Start: 1506630

End: 1507361

Strand: Reverse

Name: sdaA [H]

Synonym: Reut_B4807

Alternate gene names: 73538632

Gene position: 1507361-1506630 (Counterclockwise)

Preceding gene: 73538633

Following gene: 73538631

Centisome position: 55.29

GC content: 57.24

Gene sequence:

>732_bases
ATGGTCGGGGGCAGTATGTCCGTCAGCACATTCGATATCTTCAAGATTGAAATCGGGCCCTCTGGTTCGCATACCGCTGG
CCTGATGATGGCGCCTTGCCACTGGAACACTCCGAGCATCGACGAGCACCCGATTCCTTACCCTTTTCGGAGCCGGGAAG
AACTATGGCAGATGTGCGAGCAATCAGGACGTACCATTGCCGACCTGATGCTCGAGAATGAGAAATGCTGGCGGAGCACT
TTTGACGTTCGCGCCGGGCTACTGGTTATTGCCGCTGCGATTGAAGCTTCCATCGGGCAGGGCGGCCCCACAGGCGCAAT
TGCTGCTGTACTGCAGTACTACCGCAAGTCCGTACCCGGCGCCAATGAGGAAGGGGTTGTCGATTTCCTGCTAACGGCTG
CGGCCATAGGCATCCTCTACAGAAAAGAGGCTGCGATATCCGGAACTCAAATCCGTAACCAGGCTGAATTCGGGGTCGCA
AGTGCCATGGCGGGTGCGGGGCTGGTTGCCGTACTGGGCGGTAACAACGAGGAGATTGCGAACGCGGTTGAAATCGGATT
CGAACGAGACCTTGTCATGACCGGCGAGCCGATAGAAGGTGTGTGCAAATTTCCTGTATCGATCGCGCTGCCATGGTTGA
CATCGAGGCACGCCTCAGGTTGGGCAGATAGGAGGGACGATAGTCCGTCTTGGCAGGCCCAGAACCCACTGCGCAAGCTT
GCGTTGGCTTGA

Upstream 100 bases:

>100_bases
CATCAGTTCTATCTCGCGGTCTCAAGGATCTGATGTACTAGGGTCACGCCACAGGGCGGACGGCGCTTCGTCCGGAGCGG
TCGGAACTGGCACTGCAGGC

Downstream 100 bases:

>100_bases
CTACCACCTTGAGATCCCGATGCGCGAGACGAACTTGCACGCTTTGCGAACCCCGCTGTATGAGCGCCACCGCTTGATCC
GGGCCCGAATGGCTGATGTC

Product: L-serine ammonia-lyase

Products: NA

Alternate protein names: SDH; L-serine deaminase; L-SD [H]

Number of amino acids: Translated: 243; Mature: 243

Protein sequence:

>243_residues
MVGGSMSVSTFDIFKIEIGPSGSHTAGLMMAPCHWNTPSIDEHPIPYPFRSREELWQMCEQSGRTIADLMLENEKCWRST
FDVRAGLLVIAAAIEASIGQGGPTGAIAAVLQYYRKSVPGANEEGVVDFLLTAAAIGILYRKEAAISGTQIRNQAEFGVA
SAMAGAGLVAVLGGNNEEIANAVEIGFERDLVMTGEPIEGVCKFPVSIALPWLTSRHASGWADRRDDSPSWQAQNPLRKL
ALA

Sequences:

>Translated_243_residues
MVGGSMSVSTFDIFKIEIGPSGSHTAGLMMAPCHWNTPSIDEHPIPYPFRSREELWQMCEQSGRTIADLMLENEKCWRST
FDVRAGLLVIAAAIEASIGQGGPTGAIAAVLQYYRKSVPGANEEGVVDFLLTAAAIGILYRKEAAISGTQIRNQAEFGVA
SAMAGAGLVAVLGGNNEEIANAVEIGFERDLVMTGEPIEGVCKFPVSIALPWLTSRHASGWADRRDDSPSWQAQNPLRKL
ALA
>Mature_243_residues
MVGGSMSVSTFDIFKIEIGPSGSHTAGLMMAPCHWNTPSIDEHPIPYPFRSREELWQMCEQSGRTIADLMLENEKCWRST
FDVRAGLLVIAAAIEASIGQGGPTGAIAAVLQYYRKSVPGANEEGVVDFLLTAAAIGILYRKEAAISGTQIRNQAEFGVA
SAMAGAGLVAVLGGNNEEIANAVEIGFERDLVMTGEPIEGVCKFPVSIALPWLTSRHASGWADRRDDSPSWQAQNPLRKL
ALA

Specific function: Anaerobic degradation of L-threonine to propionate. [C]

COG id: COG1760

COG function: function code E; L-serine deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-sulfur dependent L-serine dehydratase family [H]

Homologues:

Organism=Escherichia coli, GI48994925, Length=130, Percent_Identity=39.2307692307692, Blast_Score=87, Evalue=7e-19,
Organism=Escherichia coli, GI1789161, Length=130, Percent_Identity=37.6923076923077, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1788116, Length=197, Percent_Identity=30.9644670050761, Blast_Score=81, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004644
- InterPro:   IPR005130
- InterPro:   IPR005131 [H]

Pfam domain/function: PF03313 SDH_alpha; PF03315 SDH_beta [H]

EC number: =4.3.1.17 [H]

Molecular weight: Translated: 26048; Mature: 26048

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVGGSMSVSTFDIFKIEIGPSGSHTAGLMMAPCHWNTPSIDEHPIPYPFRSREELWQMCE
CCCCCCCEEEEEEEEEEECCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHH
QSGRTIADLMLENEKCWRSTFDVRAGLLVIAAAIEASIGQGGPTGAIAAVLQYYRKSVPG
HHCCEEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCC
ANEEGVVDFLLTAAAIGILYRKEAAISGTQIRNQAEFGVASAMAGAGLVAVLGGNNEEIA
CCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHCHHHHHHHHHHHCCCEEEEECCCCHHHH
NAVEIGFERDLVMTGEPIEGVCKFPVSIALPWLTSRHASGWADRRDDSPSWQAQNPLRKL
HHHHHCCCCCEEECCCCCCHHHCCCHHEECCHHHCCCCCCCCCCCCCCCCCCHHCHHHHH
ALA
HCC
>Mature Secondary Structure
MVGGSMSVSTFDIFKIEIGPSGSHTAGLMMAPCHWNTPSIDEHPIPYPFRSREELWQMCE
CCCCCCCEEEEEEEEEEECCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHH
QSGRTIADLMLENEKCWRSTFDVRAGLLVIAAAIEASIGQGGPTGAIAAVLQYYRKSVPG
HHCCEEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCC
ANEEGVVDFLLTAAAIGILYRKEAAISGTQIRNQAEFGVASAMAGAGLVAVLGGNNEEIA
CCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHCHHHHHHHHHHHCCCEEEEECCCCHHHH
NAVEIGFERDLVMTGEPIEGVCKFPVSIALPWLTSRHASGWADRRDDSPSWQAQNPLRKL
HHHHHCCCCCEEECCCCCCHHHCCCHHEECCHHHCCCCCCCCCCCCCCCCCCHHCHHHHH
ALA
HCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]