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The map label for this gene is gcvT [H]

Identifier: 73538631

GI number: 73538631

Start: 1505459

End: 1506610

Strand: Reverse

Name: gcvT [H]

Synonym: Reut_B4806

Alternate gene names: 73538631

Gene position: 1506610-1505459 (Counterclockwise)

Preceding gene: 73538632

Following gene: 73538628

Centisome position: 55.27

GC content: 59.2

Gene sequence:

>1152_bases
ATGCGCGAGACGAACTTGCACGCTTTGCGAACCCCGCTGTATGAGCGCCACCGCTTGATCCGGGCCCGAATGGCTGATGT
CGGTGGCTGGGATCTGCCCATTGCTTATGGATCCCAGATCGAAGAGCATCACACCGTGCGAGAGGATGCCGCGATGTTCG
ATGTGTCGCACATGTGCGCGCTTGACGTTCGCGGGACTGACGCTCGAGCGTTTCTCGGCAGGCTTCTTGCCAACGACATC
GGGAAGCTGAAATCACCGGGAAAGGCGCTCTATTCGTGCATGCTTAACCGGGAAGGGGGCGTAATCGACGATCTTGTCGT
CTACTACCTTAGCGATGAATGCTTTCGCATTGTCTTGAATGCGCAGGCTGCAAGCCGTGACATTGATTGGATGCGAACGC
AGATCGTTGAGAGCGGATGTTCCGTGACACTGGTGCCACGTCGACAGGATCTTGTCACTGACGATGTGGAGGCCCTTGCG
ATGATCGCCGTGCAAGGTCCCAATGCCAGGGAGAAGGTATTTCGAGCCATGCCGTCGACGCGCGCCGCCGACAAGGTAAA
GCCATTCAATTCATGCTTCGTGCACGACGCTGTCGTCGGCGCGCTGATGCTGGCGCGCACGGGAAAGACCGGCGAGGATG
GCTTCGAGATAACGATGCTGGCGAAGCATGCCGTTCACGTATGGGACGCGTTGCGTTCGTCCGGCATCTGCGCGGCGGGA
TTCCACGCATGGGATACCCTGCGGCTCGAGGCCGGCATGCACGTGCCGGGACGGGACATGGGCCCGCAGACGTCTCCATT
TGACGTTGGCCTGGGCTGGTCTGTTGATCTCGGGGAAAAGCGGGACTTTGTTGGCAAGGCAGCGCTACAAGCTCGCGCTC
AAGCGTCGCAACTCGTCGGACTCGCGTTCGAAGGAAGCGGTGCGGTCGCGCGTACGCAGAGCCCCGTGATGAGTCTGGAA
GGGGAGGTGATCGGGAAGGTCACCAGCGGGACATATAGTCCGACGCTTCAAATGGCTATCGCTCTGGCGCTGGTTTCGCC
AGACATCAAGTTGGGCTCGTCTGTGAGTGTCGAGGTCTACAGCAAGAGAGTCTCTGCAAAAGTCGTTCGTCCACCTTTTG
TTCGGGATGGAAGCCCAGTGGGAAAACGGTAG

Upstream 100 bases:

>100_bases
GCCTCAGGTTGGGCAGATAGGAGGGACGATAGTCCGTCTTGGCAGGCCCAGAACCCACTGCGCAAGCTTGCGTTGGCTTG
ACTACCACCTTGAGATCCCG

Downstream 100 bases:

>100_bases
AGCAGTCAGTGCGACGTCCGTGGCTTCCATAGCACTGAGACGTCGCATTCATTAGTGTGCGGCCAGAAGCGACTCGCACA
TCGGGCCCCTTACCGATCAC

Product: glycine cleavage system T protein

Products: NA

Alternate protein names: Glycine cleavage system T protein [H]

Number of amino acids: Translated: 383; Mature: 383

Protein sequence:

>383_residues
MRETNLHALRTPLYERHRLIRARMADVGGWDLPIAYGSQIEEHHTVREDAAMFDVSHMCALDVRGTDARAFLGRLLANDI
GKLKSPGKALYSCMLNREGGVIDDLVVYYLSDECFRIVLNAQAASRDIDWMRTQIVESGCSVTLVPRRQDLVTDDVEALA
MIAVQGPNAREKVFRAMPSTRAADKVKPFNSCFVHDAVVGALMLARTGKTGEDGFEITMLAKHAVHVWDALRSSGICAAG
FHAWDTLRLEAGMHVPGRDMGPQTSPFDVGLGWSVDLGEKRDFVGKAALQARAQASQLVGLAFEGSGAVARTQSPVMSLE
GEVIGKVTSGTYSPTLQMAIALALVSPDIKLGSSVSVEVYSKRVSAKVVRPPFVRDGSPVGKR

Sequences:

>Translated_383_residues
MRETNLHALRTPLYERHRLIRARMADVGGWDLPIAYGSQIEEHHTVREDAAMFDVSHMCALDVRGTDARAFLGRLLANDI
GKLKSPGKALYSCMLNREGGVIDDLVVYYLSDECFRIVLNAQAASRDIDWMRTQIVESGCSVTLVPRRQDLVTDDVEALA
MIAVQGPNAREKVFRAMPSTRAADKVKPFNSCFVHDAVVGALMLARTGKTGEDGFEITMLAKHAVHVWDALRSSGICAAG
FHAWDTLRLEAGMHVPGRDMGPQTSPFDVGLGWSVDLGEKRDFVGKAALQARAQASQLVGLAFEGSGAVARTQSPVMSLE
GEVIGKVTSGTYSPTLQMAIALALVSPDIKLGSSVSVEVYSKRVSAKVVRPPFVRDGSPVGKR
>Mature_383_residues
MRETNLHALRTPLYERHRLIRARMADVGGWDLPIAYGSQIEEHHTVREDAAMFDVSHMCALDVRGTDARAFLGRLLANDI
GKLKSPGKALYSCMLNREGGVIDDLVVYYLSDECFRIVLNAQAASRDIDWMRTQIVESGCSVTLVPRRQDLVTDDVEALA
MIAVQGPNAREKVFRAMPSTRAADKVKPFNSCFVHDAVVGALMLARTGKTGEDGFEITMLAKHAVHVWDALRSSGICAAG
FHAWDTLRLEAGMHVPGRDMGPQTSPFDVGLGWSVDLGEKRDFVGKAALQARAQASQLVGLAFEGSGAVARTQSPVMSLE
GEVIGKVTSGTYSPTLQMAIALALVSPDIKLGSSVSVEVYSKRVSAKVVRPPFVRDGSPVGKR

Specific function: The glycine cleavage system catalyzes the degradation of glycine [H]

COG id: COG0404

COG function: function code E; Glycine cleavage system T protein (aminomethyltransferase)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gcvT family [H]

Homologues:

Organism=Homo sapiens, GI44662838, Length=379, Percent_Identity=34.8284960422164, Blast_Score=171, Evalue=2e-42,
Organism=Homo sapiens, GI257796258, Length=366, Percent_Identity=34.4262295081967, Blast_Score=162, Evalue=5e-40,
Organism=Homo sapiens, GI257796254, Length=379, Percent_Identity=31.3984168865435, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI257796256, Length=325, Percent_Identity=34.1538461538462, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI24797151, Length=344, Percent_Identity=29.6511627906977, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI197927446, Length=350, Percent_Identity=24.2857142857143, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI21361378, Length=350, Percent_Identity=24.2857142857143, Blast_Score=91, Evalue=3e-18,
Organism=Escherichia coli, GI1789272, Length=381, Percent_Identity=43.3070866141732, Blast_Score=283, Evalue=2e-77,
Organism=Caenorhabditis elegans, GI17560118, Length=394, Percent_Identity=28.4263959390863, Blast_Score=127, Evalue=9e-30,
Organism=Caenorhabditis elegans, GI71994052, Length=353, Percent_Identity=25.4957507082153, Blast_Score=104, Evalue=8e-23,
Organism=Caenorhabditis elegans, GI71994045, Length=353, Percent_Identity=25.4957507082153, Blast_Score=104, Evalue=9e-23,
Organism=Caenorhabditis elegans, GI32563613, Length=381, Percent_Identity=22.5721784776903, Blast_Score=76, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6320222, Length=385, Percent_Identity=29.6103896103896, Blast_Score=144, Evalue=3e-35,
Organism=Drosophila melanogaster, GI20129441, Length=383, Percent_Identity=31.5926892950392, Blast_Score=157, Evalue=2e-38,
Organism=Drosophila melanogaster, GI20130091, Length=387, Percent_Identity=25.5813953488372, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI28571104, Length=278, Percent_Identity=24.1007194244604, Blast_Score=75, Evalue=6e-14,

Paralogues:

None

Copy number: 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013977
- InterPro:   IPR006222
- InterPro:   IPR006223
- InterPro:   IPR022903 [H]

Pfam domain/function: PF01571 GCV_T; PF08669 GCV_T_C [H]

EC number: =2.1.2.10 [H]

Molecular weight: Translated: 41564; Mature: 41564

Theoretical pI: Translated: 7.89; Mature: 7.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRETNLHALRTPLYERHRLIRARMADVGGWDLPIAYGSQIEEHHTVREDAAMFDVSHMCA
CCCCCCHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEE
LDVRGTDARAFLGRLLANDIGKLKSPGKALYSCMLNREGGVIDDLVVYYLSDECFRIVLN
EECCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEEEE
AQAASRDIDWMRTQIVESGCSVTLVPRRQDLVTDDVEALAMIAVQGPNAREKVFRAMPST
CCHHCCCHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHEEEEEECCCCHHHHHHHHCCCC
RAADKVKPFNSCFVHDAVVGALMLARTGKTGEDGFEITMLAKHAVHVWDALRSSGICAAG
CCHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHCCCEEEC
FHAWDTLRLEAGMHVPGRDMGPQTSPFDVGLGWSVDLGEKRDFVGKAALQARAQASQLVG
CCHHEEEEEECCCCCCCCCCCCCCCCCEECCCCEECCCCCHHHHHHHHHHHHHHHHHHEE
LAFEGSGAVARTQSPVMSLEGEVIGKVTSGTYSPTLQMAIALALVSPDIKLGSSVSVEVY
EEEECCCCEEECCCCHHHCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCEEHHHH
SKRVSAKVVRPPFVRDGSPVGKR
HHHHHHEECCCCCCCCCCCCCCC
>Mature Secondary Structure
MRETNLHALRTPLYERHRLIRARMADVGGWDLPIAYGSQIEEHHTVREDAAMFDVSHMCA
CCCCCCHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEE
LDVRGTDARAFLGRLLANDIGKLKSPGKALYSCMLNREGGVIDDLVVYYLSDECFRIVLN
EECCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEEEE
AQAASRDIDWMRTQIVESGCSVTLVPRRQDLVTDDVEALAMIAVQGPNAREKVFRAMPST
CCHHCCCHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHEEEEEECCCCHHHHHHHHCCCC
RAADKVKPFNSCFVHDAVVGALMLARTGKTGEDGFEITMLAKHAVHVWDALRSSGICAAG
CCHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHCCCEEEC
FHAWDTLRLEAGMHVPGRDMGPQTSPFDVGLGWSVDLGEKRDFVGKAALQARAQASQLVG
CCHHEEEEEECCCCCCCCCCCCCCCCCEECCCCEECCCCCHHHHHHHHHHHHHHHHHHEE
LAFEGSGAVARTQSPVMSLEGEVIGKVTSGTYSPTLQMAIALALVSPDIKLGSSVSVEVY
EEEECCCCEEECCCCHHHCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCEEHHHH
SKRVSAKVVRPPFVRDGSPVGKR
HHHHHHEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA