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The map label for this gene is frc [H]

Identifier: 73538495

GI number: 73538495

Start: 1363812

End: 1365044

Strand: Reverse

Name: frc [H]

Synonym: Reut_B4669

Alternate gene names: 73538495

Gene position: 1365044-1363812 (Counterclockwise)

Preceding gene: 73538496

Following gene: 73538494

Centisome position: 50.07

GC content: 65.29

Gene sequence:

>1233_bases
ATGGAACGAAAAGCACTGGATGGCATCCGTGTTCTGGACATGACGCACGTTCAGGCAGGCCCTTCCGCCACGCAGCTGAT
GGCATGGATGGGCGCCGACGTGATCAAGGTGGAAATGCCGGGCCGCGGGGATATTACCCGCAGCCAGCTGCGCGACGTGC
CCAACGCCGACAGCCTGTACTTCACCATGCTCAACAGCAACAAGCGCAGCCTCACGCTGAACATGAAGACGGCGGAAGGC
AAGGCGTTGCTCGAAGACCTGATCCAGCGCAGCGACGTGCTGATCGAGAACTTCGGCCCTGGCGTGCTCGCACGTGCGGG
TTTCGACTGGGACCGCATGCAGGACCTGAACCCGCGCCTGATCTATGCATCGATCAAGGGTTTCGGCCCCGGTCCGTACC
AGGACTGCAAGGCCTATGAAAATGTGGCCCAGTGTATGGGCGGCTCGGCCTCCACGACCGGCGATGCCGCAGGCGTGCCG
ACCGTGACCGGTGCGCAGATCGGCGATTCGGGTACCGGCGTGCATTGCGTGGTCGGCATCCTGGCTGCGCTGCTGCAACG
CGAGCATTCGGGCCGCGGCCAGCGCGTGGAAGTGGCCATGCAGGATGCGGTGCTGAACCTGTGCCGCGTGAAGCTGCGCG
ACCAGCAACGGCTCGATGCGGGCCCGCTGCGCGAGTACCCCAACGAGCAGTTCGACGACCACGTGCCCCGCGCCGGCAAC
GCATCAGGCGGCGGCCAGCCTGGCGCCGCGCTGCGCTGCTCGCCCGGCGGCCCGAACGACTATGTCTACGTCATCATCCA
GCCGCAGGGCTGGGAGCCGCTGATGCGCCTGTGCGGCCGCGAAGATCTGATCACCGATCCGGAGTTCGCCTCGCCCGAGG
TGCGCCTGAAGAAGCTCGGCGAATGCTTCGGCATCATCGAGCAGTGGACCATGGGACTGACGAAGTTCGAGGTGATGAAC
GCGCTCAACGAGGTCGATGTGCCGTGCGGTCCGATCCTGTCGATGAAGGACCTGATCGAGGACCAGTCGATGTACGACCG
CGGCTATCTGGTGGAGCTGGAGCACCCGACGCGCGGCAAGTACGTGCAGCTCGGTTCGCCGATTGCACTGTCCGATTCTC
CGGTAAAGGTGGAACGTGCCCCGCTGCTGGGCGAGCACACCGAGGAAATCCTCGAGTGGCTGGGCCGCACGCCAGCCCAG
ATCGCCGCGATGAAGCTGGCCGGCGCCGTCTGA

Upstream 100 bases:

>100_bases
CCGAAGTCCACGCGAAGCGCGCCGAAAGCCGTACCGCGGAAAACACCCTGAAGACCCTGTACCAGTAAACAGACGCCATC
GGAACCGAGGAGACATCGCC

Downstream 100 bases:

>100_bases
GCGTCCGCCTTCCTCTCCTCTTCTTCCCCTGTTTCTCACACCGAGCGGGCGCGCCTGGCGCGTGCCCGCCGGAGGAGTTC
GTGCTGTGAAATCCTGGATT

Product: formyl-coenzyme A transferase

Products: NA

Alternate protein names: Formyl-CoA transferase [H]

Number of amino acids: Translated: 410; Mature: 410

Protein sequence:

>410_residues
MERKALDGIRVLDMTHVQAGPSATQLMAWMGADVIKVEMPGRGDITRSQLRDVPNADSLYFTMLNSNKRSLTLNMKTAEG
KALLEDLIQRSDVLIENFGPGVLARAGFDWDRMQDLNPRLIYASIKGFGPGPYQDCKAYENVAQCMGGSASTTGDAAGVP
TVTGAQIGDSGTGVHCVVGILAALLQREHSGRGQRVEVAMQDAVLNLCRVKLRDQQRLDAGPLREYPNEQFDDHVPRAGN
ASGGGQPGAALRCSPGGPNDYVYVIIQPQGWEPLMRLCGREDLITDPEFASPEVRLKKLGECFGIIEQWTMGLTKFEVMN
ALNEVDVPCGPILSMKDLIEDQSMYDRGYLVELEHPTRGKYVQLGSPIALSDSPVKVERAPLLGEHTEEILEWLGRTPAQ
IAAMKLAGAV

Sequences:

>Translated_410_residues
MERKALDGIRVLDMTHVQAGPSATQLMAWMGADVIKVEMPGRGDITRSQLRDVPNADSLYFTMLNSNKRSLTLNMKTAEG
KALLEDLIQRSDVLIENFGPGVLARAGFDWDRMQDLNPRLIYASIKGFGPGPYQDCKAYENVAQCMGGSASTTGDAAGVP
TVTGAQIGDSGTGVHCVVGILAALLQREHSGRGQRVEVAMQDAVLNLCRVKLRDQQRLDAGPLREYPNEQFDDHVPRAGN
ASGGGQPGAALRCSPGGPNDYVYVIIQPQGWEPLMRLCGREDLITDPEFASPEVRLKKLGECFGIIEQWTMGLTKFEVMN
ALNEVDVPCGPILSMKDLIEDQSMYDRGYLVELEHPTRGKYVQLGSPIALSDSPVKVERAPLLGEHTEEILEWLGRTPAQ
IAAMKLAGAV
>Mature_410_residues
MERKALDGIRVLDMTHVQAGPSATQLMAWMGADVIKVEMPGRGDITRSQLRDVPNADSLYFTMLNSNKRSLTLNMKTAEG
KALLEDLIQRSDVLIENFGPGVLARAGFDWDRMQDLNPRLIYASIKGFGPGPYQDCKAYENVAQCMGGSASTTGDAAGVP
TVTGAQIGDSGTGVHCVVGILAALLQREHSGRGQRVEVAMQDAVLNLCRVKLRDQQRLDAGPLREYPNEQFDDHVPRAGN
ASGGGQPGAALRCSPGGPNDYVYVIIQPQGWEPLMRLCGREDLITDPEFASPEVRLKKLGECFGIIEQWTMGLTKFEVMN
ALNEVDVPCGPILSMKDLIEDQSMYDRGYLVELEHPTRGKYVQLGSPIALSDSPVKVERAPLLGEHTEEILEWLGRTPAQ
IAAMKLAGAV

Specific function: Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate [H]

COG id: COG1804

COG function: function code C; Predicted acyl-CoA transferases/carnitine dehydratase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CaiB/BaiF CoA-transferase family [H]

Homologues:

Organism=Homo sapiens, GI300863128, Length=399, Percent_Identity=29.5739348370927, Blast_Score=169, Evalue=4e-42,
Organism=Homo sapiens, GI300863124, Length=425, Percent_Identity=28.2352941176471, Blast_Score=155, Evalue=5e-38,
Organism=Homo sapiens, GI266456254, Length=407, Percent_Identity=28.7469287469287, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI42794625, Length=407, Percent_Identity=28.7469287469287, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI13376042, Length=421, Percent_Identity=25.8907363420428, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI300863126, Length=152, Percent_Identity=38.1578947368421, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI266458397, Length=278, Percent_Identity=30.2158273381295, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI266458393, Length=284, Percent_Identity=29.9295774647887, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI266458395, Length=126, Percent_Identity=38.0952380952381, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI42822893, Length=126, Percent_Identity=38.0952380952381, Blast_Score=77, Evalue=3e-14,
Organism=Escherichia coli, GI1788717, Length=412, Percent_Identity=54.126213592233, Blast_Score=412, Evalue=1e-116,
Organism=Escherichia coli, GI87082093, Length=396, Percent_Identity=33.3333333333333, Blast_Score=183, Evalue=2e-47,
Organism=Escherichia coli, GI1786222, Length=345, Percent_Identity=24.9275362318841, Blast_Score=79, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24648431, Length=414, Percent_Identity=32.8502415458937, Blast_Score=193, Evalue=2e-49,
Organism=Drosophila melanogaster, GI24585488, Length=197, Percent_Identity=29.9492385786802, Blast_Score=83, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003673
- InterPro:   IPR017659 [H]

Pfam domain/function: PF02515 CoA_transf_3 [H]

EC number: =2.8.3.16 [H]

Molecular weight: Translated: 44648; Mature: 44648

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERKALDGIRVLDMTHVQAGPSATQLMAWMGADVIKVEMPGRGDITRSQLRDVPNADSLY
CCCCCCCCEEEEEEEECCCCCCHHHHHHHHCCCEEEEECCCCCCCCHHHHHCCCCCCCEE
FTMLNSNKRSLTLNMKTAEGKALLEDLIQRSDVLIENFGPGVLARAGFDWDRMQDLNPRL
EEEECCCCEEEEEEEECCCHHHHHHHHHHHCCEEEECCCCCEEEECCCCHHHHCCCCCEE
IYASIKGFGPGPYQDCKAYENVAQCMGGSASTTGDAAGVPTVTGAQIGDSGTGVHCVVGI
EEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHH
LAALLQREHSGRGQRVEVAMQDAVLNLCRVKLRDQQRLDAGPLREYPNEQFDDHVPRAGN
HHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCHHHCCCCCCCC
ASGGGQPGAALRCSPGGPNDYVYVIIQPQGWEPLMRLCGREDLITDPEFASPEVRLKKLG
CCCCCCCCCEEEECCCCCCCEEEEEEECCCCHHHHHHCCCCCCCCCCCCCCCHHHHHHHH
ECFGIIEQWTMGLTKFEVMNALNEVDVPCGPILSMKDLIEDQSMYDRGYLVELEHPTRGK
HHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCEEEECCCCCCC
YVQLGSPIALSDSPVKVERAPLLGEHTEEILEWLGRTPAQIAAMKLAGAV
EEECCCCEEECCCCCEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MERKALDGIRVLDMTHVQAGPSATQLMAWMGADVIKVEMPGRGDITRSQLRDVPNADSLY
CCCCCCCCEEEEEEEECCCCCCHHHHHHHHCCCEEEEECCCCCCCCHHHHHCCCCCCCEE
FTMLNSNKRSLTLNMKTAEGKALLEDLIQRSDVLIENFGPGVLARAGFDWDRMQDLNPRL
EEEECCCCEEEEEEEECCCHHHHHHHHHHHCCEEEECCCCCEEEECCCCHHHHCCCCCEE
IYASIKGFGPGPYQDCKAYENVAQCMGGSASTTGDAAGVPTVTGAQIGDSGTGVHCVVGI
EEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHH
LAALLQREHSGRGQRVEVAMQDAVLNLCRVKLRDQQRLDAGPLREYPNEQFDDHVPRAGN
HHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCHHHCCCCCCCC
ASGGGQPGAALRCSPGGPNDYVYVIIQPQGWEPLMRLCGREDLITDPEFASPEVRLKKLG
CCCCCCCCCEEEECCCCCCCEEEEEEECCCCHHHHHHCCCCCCCCCCCCCCCHHHHHHHH
ECFGIIEQWTMGLTKFEVMNALNEVDVPCGPILSMKDLIEDQSMYDRGYLVELEHPTRGK
HHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCEEEECCCCCCC
YVQLGSPIALSDSPVKVERAPLLGEHTEEILEWLGRTPAQIAAMKLAGAV
EEECCCCEEECCCCCEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]