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The map label for this gene is ycgM [C]

Identifier: 73538494

GI number: 73538494

Start: 1362944

End: 1363726

Strand: Reverse

Name: ycgM [C]

Synonym: Reut_B4668

Alternate gene names: 73538494

Gene position: 1363726-1362944 (Counterclockwise)

Preceding gene: 73538495

Following gene: 73538493

Centisome position: 50.02

GC content: 65.26

Gene sequence:

>783_bases
GTGAAATCCTGGATTCGTTTTCGCCGTCCCGACGGCAGCGTCGGCTACGGCCGCACGGAAGGCGACGGCAGCGACTGCGT
CATTGAGTTCGATGGCCCCGGCTATGTCGATCCTCAACCCGCGGGCGCCACTTACAAGCTTGGCGAACTGCATCTGCTCG
CCCCGTGCGAGCCCGGCAAGGTCGTGGCGCTTTGGAACAACTTCCACGCTCTGGCACGCAAGCTGGAAAAGCCCGTGCCA
ACCCATCCGCTGTTCCTGATCAAGCCGGCCACTTCGCTGGCGGGCCCTGGCGATGCCGTGGAGCGGCCGCGCAGCTATGA
CGGCAAGATCGTCTACGAGGGCGAGCTTGGCATCGTGATCGGCAAGAAGGCGCGCAACGTGTCGGTGACCGAGGCGGCAT
CGCACATCTTCGGCTACACCGTCGTCAACGACGTGACCGCCGCCGAGCTGATCGCTGCCGACCCGAATTTCCCGCAGTGG
ACCCGTGCCAAGGGCTTCGACACCTTCGGCTGCGTCGGTCCGGCCATCGTGCCCGGTTTCAACTGGCGCGCGGCCAGCGT
AAAGACACGCCTCGACGGCGTGGAGCGGCAGAACTACCCGCTCTCGGACATGATCTTCACGCCCGAAGAGCAGGTCAGCC
GCATCTCGCAGGACCTGACGCTGATGCCGGGCGACGTGATCGCTGTCGGCACCTCGCTGGGCGTGGGCTCGATGAAGGAT
GGCGCGGTGGTGGAGGTGAGCATCGAAGGCATCGGCTCGCTGGTGAACCACGTTCGCGGGTAA

Upstream 100 bases:

>100_bases
GCCGGCGCCGTCTGAGCGTCCGCCTTCCTCTCCTCTTCTTCCCCTGTTTCTCACACCGAGCGGGCGCGCCTGGCGCGTGC
CCGCCGGAGGAGTTCGTGCT

Downstream 100 bases:

>100_bases
TCGCGCAATAATCAAAGGGAAAGCCATGCCAATGACAATTGGTGTCCCCCGGGAGGTCCATCCCGGGGAGCGGCGCGTTG
CCGCGACGCCCGATTCGGTC

Product: fumarylacetoacetate (FAA) hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MKSWIRFRRPDGSVGYGRTEGDGSDCVIEFDGPGYVDPQPAGATYKLGELHLLAPCEPGKVVALWNNFHALARKLEKPVP
THPLFLIKPATSLAGPGDAVERPRSYDGKIVYEGELGIVIGKKARNVSVTEAASHIFGYTVVNDVTAAELIAADPNFPQW
TRAKGFDTFGCVGPAIVPGFNWRAASVKTRLDGVERQNYPLSDMIFTPEEQVSRISQDLTLMPGDVIAVGTSLGVGSMKD
GAVVEVSIEGIGSLVNHVRG

Sequences:

>Translated_260_residues
MKSWIRFRRPDGSVGYGRTEGDGSDCVIEFDGPGYVDPQPAGATYKLGELHLLAPCEPGKVVALWNNFHALARKLEKPVP
THPLFLIKPATSLAGPGDAVERPRSYDGKIVYEGELGIVIGKKARNVSVTEAASHIFGYTVVNDVTAAELIAADPNFPQW
TRAKGFDTFGCVGPAIVPGFNWRAASVKTRLDGVERQNYPLSDMIFTPEEQVSRISQDLTLMPGDVIAVGTSLGVGSMKD
GAVVEVSIEGIGSLVNHVRG
>Mature_260_residues
MKSWIRFRRPDGSVGYGRTEGDGSDCVIEFDGPGYVDPQPAGATYKLGELHLLAPCEPGKVVALWNNFHALARKLEKPVP
THPLFLIKPATSLAGPGDAVERPRSYDGKIVYEGELGIVIGKKARNVSVTEAASHIFGYTVVNDVTAAELIAADPNFPQW
TRAKGFDTFGCVGPAIVPGFNWRAASVKTRLDGVERQNYPLSDMIFTPEEQVSRISQDLTLMPGDVIAVGTSLGVGSMKD
GAVVEVSIEGIGSLVNHVRG

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI40786394, Length=222, Percent_Identity=34.6846846846847, Blast_Score=116, Evalue=2e-26,
Organism=Homo sapiens, GI156231349, Length=222, Percent_Identity=34.6846846846847, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI13654274, Length=204, Percent_Identity=30.8823529411765, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI66348062, Length=196, Percent_Identity=31.1224489795918, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI215422413, Length=196, Percent_Identity=31.1224489795918, Blast_Score=86, Evalue=4e-17,
Organism=Escherichia coli, GI1787428, Length=196, Percent_Identity=27.5510204081633, Blast_Score=77, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17557057, Length=197, Percent_Identity=29.4416243654822, Blast_Score=74, Evalue=8e-14,
Organism=Saccharomyces cerevisiae, GI6324161, Length=225, Percent_Identity=27.1111111111111, Blast_Score=69, Evalue=9e-13,
Organism=Drosophila melanogaster, GI28572127, Length=221, Percent_Identity=35.7466063348416, Blast_Score=123, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24663695, Length=225, Percent_Identity=34.6666666666667, Blast_Score=107, Evalue=6e-24,
Organism=Drosophila melanogaster, GI28571789, Length=204, Percent_Identity=31.3725490196078, Blast_Score=89, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: NA

Molecular weight: Translated: 27877; Mature: 27877

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSWIRFRRPDGSVGYGRTEGDGSDCVIEFDGPGYVDPQPAGATYKLGELHLLAPCEPGK
CCCCCEEECCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCEEEECCEEEECCCCCCC
VVALWNNFHALARKLEKPVPTHPLFLIKPATSLAGPGDAVERPRSYDGKIVYEGELGIVI
EEEEECCHHHHHHHHCCCCCCCCEEEEECCCCCCCCCHHHHCCCCCCCEEEEECCEEEEE
GKKARNVSVTEAASHIFGYTVVNDVTAAELIAADPNFPQWTRAKGFDTFGCVGPAIVPGF
CCCCCCCCHHHHHHHHHHHHHHCCCCHHHEEECCCCCCCCCCCCCCCCCCCCCCHHCCCC
NWRAASVKTRLDGVERQNYPLSDMIFTPEEQVSRISQDLTLMPGDVIAVGTSLGVGSMKD
CCCHHHHHHHHCCCCCCCCCHHHEEECCHHHHHHHHHCCEECCCCEEEEECCCCCCCCCC
GAVVEVSIEGIGSLVNHVRG
CCEEEEEHHHHHHHHHHHCC
>Mature Secondary Structure
MKSWIRFRRPDGSVGYGRTEGDGSDCVIEFDGPGYVDPQPAGATYKLGELHLLAPCEPGK
CCCCCEEECCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCEEEECCEEEECCCCCCC
VVALWNNFHALARKLEKPVPTHPLFLIKPATSLAGPGDAVERPRSYDGKIVYEGELGIVI
EEEEECCHHHHHHHHCCCCCCCCEEEEECCCCCCCCCHHHHCCCCCCCEEEEECCEEEEE
GKKARNVSVTEAASHIFGYTVVNDVTAAELIAADPNFPQWTRAKGFDTFGCVGPAIVPGF
CCCCCCCCHHHHHHHHHHHHHHCCCCHHHEEECCCCCCCCCCCCCCCCCCCCCCHHCCCC
NWRAASVKTRLDGVERQNYPLSDMIFTPEEQVSRISQDLTLMPGDVIAVGTSLGVGSMKD
CCCHHHHHHHHCCCCCCCCCHHHEEECCHHHHHHHHHCCEECCCCEEEEECCCCCCCCCC
GAVVEVSIEGIGSLVNHVRG
CCEEEEEHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]