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The map label for this gene is cmpR [H]

Identifier: 73538431

GI number: 73538431

Start: 1290035

End: 1290919

Strand: Direct

Name: cmpR [H]

Synonym: Reut_B4604

Alternate gene names: 73538431

Gene position: 1290035-1290919 (Clockwise)

Preceding gene: 73538429

Following gene: 73538432

Centisome position: 47.32

GC content: 67.8

Gene sequence:

>885_bases
ATGCGAGAGATCAGCCTGGACCGCCTGCGCACGCTGGTCGCCATTGCCGACCATGGCTCATTCGCCGGGGCGGCGCGCGC
CTTGCACCTTGCGCCGCCCACGGTCAGCCTCCACATCGCGGAACTGGAACACCGCATCGGTGCGCCGCTGCTGTCGCGAA
AACGCGGACAGGTAAGGCCGTCGGCGATCGGAGAGGTGCTGTTGGAGCGCGGGCGCCGGCTGCTGGCCGATGCCGAGCAG
GCGCTGGACGATATACAGCGACAGGTGGAAGGGCTCGAAGGGCGCGCCCGGCTCGGCGCGTCGACTGGCGCGATCGCGCA
CCTGCTGCCGCAGGCGCTGGAGGTGCTGCGCCAGCAGCATCCCGGCATCGACATTCAGATCGCGGTCCTGACTTCGCAGG
AAACACTGTCACGGCTGGCGGACGGTACGCTCGATATCGGGCTGGTGGCACTGCCTCAGCCGCCGGTAGCCGGACTGGTG
ATCAAGCCCTGGCGCCGCGACCCCGTGATGGCCTTCGTGCCGGGACATTGGCAGTGCCCGGCCCGCGTCACGCCGGAATG
GCTCGCCGCCCAGCCGTTGATTCTCAATGACGCGACCACGCGCCTCTCGCGTCAGACTGCGGAGTGGTTCGCGGCCGCGG
GACACCATCCTGCCCCACGCATTCAGCTCAACTACAACGACGCGATCAAGAGCCTCGTCGCAGCGGGTTACGGCGCCGCG
CTGTTGCCCCACGAGGCCACCACGCCATTGCCGGACAAGCGCATCGTCATGCGTCCACTGCGCCCTGCACTATGGCGTCG
GCTCGGCATCGCGCATCGTGCGGGGTACGTTGAACGCTCCACCCAACACGTTCTGGATGTGCTGTGGGATCTGCGGTTGG
TGTAA

Upstream 100 bases:

>100_bases
GAAGGACGTCGACGGAGCCCCAATCTTCCATCGACCGCTAAAATAGGGAAAGTTGAATTTCACAACCTTGACGTTCAGTT
TTCCTGAATCGGGAGCCGAC

Downstream 100 bases:

>100_bases
TCGTTGCCAGTCCCTGCTTCGGTGCACACGCGCCCCGCGCAGGCGCCAGAGTTGCCAGCGCTTGACATCGGGGCCGGTAC
AAGCTTTGCTTGCGATAGGA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 294; Mature: 294

Protein sequence:

>294_residues
MREISLDRLRTLVAIADHGSFAGAARALHLAPPTVSLHIAELEHRIGAPLLSRKRGQVRPSAIGEVLLERGRRLLADAEQ
ALDDIQRQVEGLEGRARLGASTGAIAHLLPQALEVLRQQHPGIDIQIAVLTSQETLSRLADGTLDIGLVALPQPPVAGLV
IKPWRRDPVMAFVPGHWQCPARVTPEWLAAQPLILNDATTRLSRQTAEWFAAAGHHPAPRIQLNYNDAIKSLVAAGYGAA
LLPHEATTPLPDKRIVMRPLRPALWRRLGIAHRAGYVERSTQHVLDVLWDLRLV

Sequences:

>Translated_294_residues
MREISLDRLRTLVAIADHGSFAGAARALHLAPPTVSLHIAELEHRIGAPLLSRKRGQVRPSAIGEVLLERGRRLLADAEQ
ALDDIQRQVEGLEGRARLGASTGAIAHLLPQALEVLRQQHPGIDIQIAVLTSQETLSRLADGTLDIGLVALPQPPVAGLV
IKPWRRDPVMAFVPGHWQCPARVTPEWLAAQPLILNDATTRLSRQTAEWFAAAGHHPAPRIQLNYNDAIKSLVAAGYGAA
LLPHEATTPLPDKRIVMRPLRPALWRRLGIAHRAGYVERSTQHVLDVLWDLRLV
>Mature_294_residues
MREISLDRLRTLVAIADHGSFAGAARALHLAPPTVSLHIAELEHRIGAPLLSRKRGQVRPSAIGEVLLERGRRLLADAEQ
ALDDIQRQVEGLEGRARLGASTGAIAHLLPQALEVLRQQHPGIDIQIAVLTSQETLSRLADGTLDIGLVALPQPPVAGLV
IKPWRRDPVMAFVPGHWQCPARVTPEWLAAQPLILNDATTRLSRQTAEWFAAAGHHPAPRIQLNYNDAIKSLVAAGYGAA
LLPHEATTPLPDKRIVMRPLRPALWRRLGIAHRAGYVERSTQHVLDVLWDLRLV

Specific function: Activates transcription of the cmpABCD operon under carbon dioxide-limited conditions [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787879, Length=249, Percent_Identity=28.9156626506024, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI1790399, Length=280, Percent_Identity=25.7142857142857, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI1790208, Length=262, Percent_Identity=26.3358778625954, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788748, Length=299, Percent_Identity=27.4247491638796, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1788887, Length=266, Percent_Identity=27.8195488721804, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1790262, Length=277, Percent_Identity=27.7978339350181, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1788297, Length=249, Percent_Identity=25.7028112449799, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1787601, Length=265, Percent_Identity=24.5283018867925, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1788481, Length=299, Percent_Identity=26.7558528428094, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI2367136, Length=265, Percent_Identity=23.0188679245283, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI157672245, Length=239, Percent_Identity=24.2677824267782, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI87081904, Length=154, Percent_Identity=31.8181818181818, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI1787806, Length=252, Percent_Identity=23.4126984126984, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32228; Mature: 32228

Theoretical pI: Translated: 10.56; Mature: 10.56

Prosite motif: PS50931 HTH_LYSR ; PS00228 TUBULIN_B_AUTOREG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREISLDRLRTLVAIADHGSFAGAARALHLAPPTVSLHIAELEHRIGAPLLSRKRGQVRP
CCCCCHHHHHHHHHHHCCCCHHHHHHEEEECCCCCEEEHHHHHHHHCCHHHHCCCCCCCH
SAIGEVLLERGRRLLADAEQALDDIQRQVEGLEGRARLGASTGAIAHLLPQALEVLRQQH
HHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHHHHHHHHC
PGIDIQIAVLTSQETLSRLADGTLDIGLVALPQPPVAGLVIKPWRRDPVMAFVPGHWQCP
CCCEEEEEEEECHHHHHHHHCCCCCEEEEECCCCCCCCEEECCCCCCCEEEECCCCCCCC
ARVTPEWLAAQPLILNDATTRLSRQTAEWFAAAGHHPAPRIQLNYNDAIKSLVAAGYGAA
CCCCHHHHCCCCEEECHHHHHHHHHHHHHHHHCCCCCCCEEEECHHHHHHHHHHHCCCCE
LLPHEATTPLPDKRIVMRPLRPALWRRLGIAHRAGYVERSTQHVLDVLWDLRLV
ECCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MREISLDRLRTLVAIADHGSFAGAARALHLAPPTVSLHIAELEHRIGAPLLSRKRGQVRP
CCCCCHHHHHHHHHHHCCCCHHHHHHEEEECCCCCEEEHHHHHHHHCCHHHHCCCCCCCH
SAIGEVLLERGRRLLADAEQALDDIQRQVEGLEGRARLGASTGAIAHLLPQALEVLRQQH
HHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHHHHHHHHC
PGIDIQIAVLTSQETLSRLADGTLDIGLVALPQPPVAGLVIKPWRRDPVMAFVPGHWQCP
CCCEEEEEEEECHHHHHHHHCCCCCEEEEECCCCCCCCEEECCCCCCCEEEECCCCCCCC
ARVTPEWLAAQPLILNDATTRLSRQTAEWFAAAGHHPAPRIQLNYNDAIKSLVAAGYGAA
CCCCHHHHCCCCEEECHHHHHHHHHHHHHHHHCCCCCCCEEEECHHHHHHHHHHHCCCCE
LLPHEATTPLPDKRIVMRPLRPALWRRLGIAHRAGYVERSTQHVLDVLWDLRLV
ECCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA