Click here to switch to the map view.

The map label for this gene is ompR [H]

Identifier: 73538429

GI number: 73538429

Start: 1287617

End: 1288807

Strand: Direct

Name: ompR [H]

Synonym: Reut_B4602

Alternate gene names: 73538429

Gene position: 1287617-1288807 (Clockwise)

Preceding gene: 73538418

Following gene: 73538431

Centisome position: 47.23

GC content: 61.54

Gene sequence:

>1191_bases
ATGCCAGGTCATGTATTGATTGTCGATGATGATGCGGAGACCCGCAGGCTGCTGCGCGAGTATCTGCAAAAGCAGGGCTA
TCGCGCGACGGCCGTAGCCGATGGTCGCGCCTTGCGTGCCGCCCTCGGTACGGCGCGCCCGGATCTCATCGTCCTCGATC
TGATGCTGGCTGGGAAGGATGGCCTGGAACTATGCCGCGACCTGCGCACCCGTTCCAATTTGCCGATCATCATGCTTACT
GCGCGCGACGAGGAGACCGACCGCGTGGTCGGACTGGAGATGGGCGCCGACGACTACGTTGTGAAGCCCTTCAATCCGCG
CGAATTACTCGCCCGGATCAAAAGCGTACTGAGACGCGCCCGCTCGCTACCTGATAACCTGGAGCCCGAAGCAGCCGCGT
GGTTCAAGTTCAGCGGGTGGGTGCTCGATGCCGCAACCCGCAACCTCACCTCCGACCGCGCACCCATGCCCGAGGACGGA
CCACTGGAGGTCGCGCGCGCGGCACACGCTTTCAATACCATGCGAGCGAGCCTGAGCCGCTACCTTCGAGAGCGCAGTGC
TACGCTTGCGGCGATGTCGCATGACTTGAAGACGCCGATCACCCGCTTGCGCCTGCGCGCCGAACTGCTTGACGACGGAG
AGCTGAAACAAGAGATCTCCCAGGACTTGCATGACATGGAGTCGATGGTGCAGGCCACGCTCGCGTTCATGCGCGGAGGG
GACAGCGCGGAACCAATCCAGCCCCTTGACGTGACGGCATTGCTCGAGAGCCTGCAGGCCGATGCGGAAGAGGTCGGTGC
GCACGTTTCAATCGAAGGAAGCACCGACAGGCCATATCCTGGCCGCCCGCAAGCGCTCAAGCGCTGCCTTAGCAACCTTG
TGGATAACGCATGCAAGTATGGAAATCGCGCAGAAATCCTGGTCGAGGACGACGAGAGGCAACTCGTAATACGCGTTCTG
GATCAGGGGCCCGGCATTTCCGAGGCGCAGCTCGAGCGCGTGTTTGAGCCTTTCTATCGCATTGAGAGATCCCGCAGCCG
CGATACCGGAGGCACCGGATTAGGCCTGACGATCGCCCGAGCGATCGCTCAAATTCACGGCGGCACATTGGTACTGCACA
ACTTGAAACGCGGAGGCCTGGAGGCAATGTTGACGCTTCCGAGGCCAGCAACTGTAATCGACGATCGCTGA

Upstream 100 bases:

>100_bases
CTTTTTCCTTGGTGCGCTTCTGCACCTCGACGTGTGCCGTTTTTGCCACATTTTGACGATCCTCGGGCGTCTTGGCATTG
CGCATCGTAAGGCTCTCGCC

Downstream 100 bases:

>100_bases
TCCCGCGAGAATCCCATCGGTGACATATCCGCGGGGCTCTTGCACTGGAGGGGAAAGTGGAAGGGCCGTTGAGGGTCGGA
AACCCGAAGTTTGCGACCGC

Product: response regulator receiver ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 396; Mature: 395

Protein sequence:

>396_residues
MPGHVLIVDDDAETRRLLREYLQKQGYRATAVADGRALRAALGTARPDLIVLDLMLAGKDGLELCRDLRTRSNLPIIMLT
ARDEETDRVVGLEMGADDYVVKPFNPRELLARIKSVLRRARSLPDNLEPEAAAWFKFSGWVLDAATRNLTSDRAPMPEDG
PLEVARAAHAFNTMRASLSRYLRERSATLAAMSHDLKTPITRLRLRAELLDDGELKQEISQDLHDMESMVQATLAFMRGG
DSAEPIQPLDVTALLESLQADAEEVGAHVSIEGSTDRPYPGRPQALKRCLSNLVDNACKYGNRAEILVEDDERQLVIRVL
DQGPGISEAQLERVFEPFYRIERSRSRDTGGTGLGLTIARAIAQIHGGTLVLHNLKRGGLEAMLTLPRPATVIDDR

Sequences:

>Translated_396_residues
MPGHVLIVDDDAETRRLLREYLQKQGYRATAVADGRALRAALGTARPDLIVLDLMLAGKDGLELCRDLRTRSNLPIIMLT
ARDEETDRVVGLEMGADDYVVKPFNPRELLARIKSVLRRARSLPDNLEPEAAAWFKFSGWVLDAATRNLTSDRAPMPEDG
PLEVARAAHAFNTMRASLSRYLRERSATLAAMSHDLKTPITRLRLRAELLDDGELKQEISQDLHDMESMVQATLAFMRGG
DSAEPIQPLDVTALLESLQADAEEVGAHVSIEGSTDRPYPGRPQALKRCLSNLVDNACKYGNRAEILVEDDERQLVIRVL
DQGPGISEAQLERVFEPFYRIERSRSRDTGGTGLGLTIARAIAQIHGGTLVLHNLKRGGLEAMLTLPRPATVIDDR
>Mature_395_residues
PGHVLIVDDDAETRRLLREYLQKQGYRATAVADGRALRAALGTARPDLIVLDLMLAGKDGLELCRDLRTRSNLPIIMLTA
RDEETDRVVGLEMGADDYVVKPFNPRELLARIKSVLRRARSLPDNLEPEAAAWFKFSGWVLDAATRNLTSDRAPMPEDGP
LEVARAAHAFNTMRASLSRYLRERSATLAAMSHDLKTPITRLRLRAELLDDGELKQEISQDLHDMESMVQATLAFMRGGD
SAEPIQPLDVTALLESLQADAEEVGAHVSIEGSTDRPYPGRPQALKRCLSNLVDNACKYGNRAEILVEDDERQLVIRVLD
QGPGISEAQLERVFEPFYRIERSRSRDTGGTGLGLTIARAIAQIHGGTLVLHNLKRGGLEAMLTLPRPATVIDDR

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=204, Percent_Identity=44.1176470588235, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1789808, Length=246, Percent_Identity=34.1463414634146, Blast_Score=128, Evalue=6e-31,
Organism=Escherichia coli, GI1790863, Length=147, Percent_Identity=40.8163265306122, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI1788394, Length=117, Percent_Identity=48.7179487179487, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1790346, Length=245, Percent_Identity=33.469387755102, Blast_Score=121, Evalue=8e-29,
Organism=Escherichia coli, GI1787229, Length=157, Percent_Identity=40.1273885350318, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1786599, Length=173, Percent_Identity=38.150289017341, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI1787894, Length=243, Percent_Identity=30.8641975308642, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1786911, Length=149, Percent_Identity=44.2953020134228, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI87082012, Length=153, Percent_Identity=39.2156862745098, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1788393, Length=274, Percent_Identity=27.3722627737226, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI2367329, Length=116, Percent_Identity=47.4137931034483, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1790860, Length=120, Percent_Identity=40.8333333333333, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1790861, Length=256, Percent_Identity=27.734375, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1786783, Length=248, Percent_Identity=27.8225806451613, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1790552, Length=119, Percent_Identity=42.0168067226891, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI145693140, Length=102, Percent_Identity=40.1960784313725, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1787375, Length=122, Percent_Identity=40.9836065573771, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI1789402, Length=123, Percent_Identity=36.5853658536585, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1786784, Length=147, Percent_Identity=36.0544217687075, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1786912, Length=223, Percent_Identity=32.2869955156951, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI87081816, Length=215, Percent_Identity=29.7674418604651, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI48994928, Length=248, Percent_Identity=25.8064516129032, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1786600, Length=219, Percent_Identity=26.027397260274, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1789149, Length=216, Percent_Identity=30.5555555555556, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI145693157, Length=203, Percent_Identity=26.6009852216749, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1787374, Length=218, Percent_Identity=27.9816513761468, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1788279, Length=260, Percent_Identity=25.7692307692308, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1788550, Length=106, Percent_Identity=33.0188679245283, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1790551, Length=234, Percent_Identity=29.4871794871795, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1788713, Length=226, Percent_Identity=25.6637168141593, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1790299, Length=116, Percent_Identity=32.7586206896552, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1789403, Length=244, Percent_Identity=26.2295081967213, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI87082128, Length=234, Percent_Identity=26.9230769230769, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 43869; Mature: 43738

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGHVLIVDDDAETRRLLREYLQKQGYRATAVADGRALRAALGTARPDLIVLDLMLAGKD
CCCCEEEECCCHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHCCCCCCCEEEEHHHCCCC
GLELCRDLRTRSNLPIIMLTARDEETDRVVGLEMGADDYVVKPFNPRELLARIKSVLRRA
HHHHHHHHHHCCCCCEEEEEECCCCCCCEEEEEECCCCCEECCCCHHHHHHHHHHHHHHH
RSLPDNLEPEAAAWFKFSGWVLDAATRNLTSDRAPMPEDGPLEVARAAHAFNTMRASLSR
HCCCCCCCCCHHHEEEECCEEEEHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
YLRERSATLAAMSHDLKTPITRLRLRAELLDDGELKQEISQDLHDMESMVQATLAFMRGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DSAEPIQPLDVTALLESLQADAEEVGAHVSIEGSTDRPYPGRPQALKRCLSNLVDNACKY
CCCCCCCCCHHHHHHHHHHCCHHHCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCC
GNRAEILVEDDERQLVIRVLDQGPGISEAQLERVFEPFYRIERSRSRDTGGTGLGLTIAR
CCCEEEEEECCCCEEHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
AIAQIHGGTLVLHNLKRGGLEAMLTLPRPATVIDDR
HHHHHCCCEEEEECCCCCCCEEEEECCCCCCCCCCC
>Mature Secondary Structure 
PGHVLIVDDDAETRRLLREYLQKQGYRATAVADGRALRAALGTARPDLIVLDLMLAGKD
CCCEEEECCCHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHCCCCCCCEEEEHHHCCCC
GLELCRDLRTRSNLPIIMLTARDEETDRVVGLEMGADDYVVKPFNPRELLARIKSVLRRA
HHHHHHHHHHCCCCCEEEEEECCCCCCCEEEEEECCCCCEECCCCHHHHHHHHHHHHHHH
RSLPDNLEPEAAAWFKFSGWVLDAATRNLTSDRAPMPEDGPLEVARAAHAFNTMRASLSR
HCCCCCCCCCHHHEEEECCEEEEHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
YLRERSATLAAMSHDLKTPITRLRLRAELLDDGELKQEISQDLHDMESMVQATLAFMRGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DSAEPIQPLDVTALLESLQADAEEVGAHVSIEGSTDRPYPGRPQALKRCLSNLVDNACKY
CCCCCCCCCHHHHHHHHHHCCHHHCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCC
GNRAEILVEDDERQLVIRVLDQGPGISEAQLERVFEPFYRIERSRSRDTGGTGLGLTIAR
CCCEEEEEECCCCEEHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
AIAQIHGGTLVLHNLKRGGLEAMLTLPRPATVIDDR
HHHHHCCCEEEEECCCCCCCEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]