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The map label for this gene is ttuB [H]

Identifier: 73538363

GI number: 73538363

Start: 1209860

End: 1211191

Strand: Direct

Name: ttuB [H]

Synonym: Reut_B4536

Alternate gene names: 73538363

Gene position: 1209860-1211191 (Clockwise)

Preceding gene: 73538362

Following gene: 73538364

Centisome position: 44.38

GC content: 64.86

Gene sequence:

>1332_bases
ATGCATTCCGCGCAGACCCTGCGCAATCCCGCAACGAACACTGCGACGACGGACACGATGCAGGCGTACGACAACGCGCT
CTATCGAAAGGTGGCATGGAGACTGCTGCCATTCCTGATGGCCTGCTACATCGCGGCCTTCCTGGACCGCGTCAACGTCG
GCTTCGCCAAGCTCCAGATGCTGGACCAGCTCAAGTTCAGCGACACGATATACGGCCTTGGCGCCGGCATCTTCTTCATC
GGCTACTTCCTGTTCGAAGTCCCGAGCAATGTGCTGATGCACCGCATCGGCGCGAAAAAGACGCTCGCGCGCATCATGAT
CCTCTGGGCCTGCATCTCGGCCTGCATGGCGCTGACCAAGACGCCGACTCAGTTCTACATCCTGCGCTTCCTGCTGGGCG
CGGCCGAGGCCGGCTTCTATCCCGGCATCATCCTGTACCTGACGTACTGGTTCCCGTCGCACCGCCGCGGGCAGGTCATC
GCAGTCTTCATGACAGCCGTGCCGTTCGCCGGCATCCTCGGCGGCCCGCTGTCGGGCTGGATCATGGAGAGCCTGCACGA
CCACCATGGCTTCGCCGGCTGGCAGTGGATGTTCCTGATCGAAGCGATTCCGTCGATCGTGCTGGGCCTGGCCGTGCTCT
GGTATCTCGACGACCGCATCACCGACGCGCGCTGGCTCGACACCGCCGAGAAGAACCGGCTCGCACACAACATTGCGGCG
GAGAAGACGACCAAGGTCGATCACGTATCGCTGCTGACGCTGTTCCGTGACCGCCGCGTGATCCACATGGCGCTGATCTG
CTACTGCACGGTATCGAGCCTGTCGGGCCTGGCCTTCTGGATTCCGTCGGTGATCCGCTCGACGGGCGTGGTGTCGTTGC
TGGACGTGGGGCTGCTGACGGCGATCCCGAACGCCTGTGCGGTCGTGTCGATGATCCTGGTATGCCGGCACTCTGACCGC
ACTCGAGAGCGCCGCTGGCACATGGTCATCCCGTTCCTGGTCGGGGGCGCCGGCCTGACGCTCAGCACGCTGTTCAGCCA
CAACCCCACGTTCGCGGTGGCGATGCTGTCCGTCGCGGCCGCTGGCTGCATGGTCTGCTCGCCGCTGTTCTGGAGCCTGC
CGACCGCATTCCTCGAAGGCCGCAGCGCCGCTGCCGGCATCGCCGCGATCAACTCGTTCGCCGGTCTGGCCGCCTTCGCC
AGCCCCTACGCGATCGGCTGGATCAAGGACCTGACCGGCTCCACCGACTGGGGCATGTACTTCCTCGCCTCCTTCACCGT
GATCGGCGCGCTGCTGGTGCTGCGCGTGCCGGCAACGCTGGTCAACCGCTGA

Upstream 100 bases:

>100_bases
CAAATCTAGAAAGAAGAACACGATGCAGGCGCCTCCGGGCGCCCGCAGGGGGGCGTTTTTGTCTCACCAAATCCAAAGGA
GGAACATAGTGAGCGATTCA

Downstream 100 bases:

>100_bases
TTGCACAGGACGTACCACGATGAACAACCAGACAGACAATCTCAGCGACGTCATTGCGCTGACGCGCGAGATGGTGCGCA
TTCCGAGCCTCTCCGGCCGC

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 443; Mature: 443

Protein sequence:

>443_residues
MHSAQTLRNPATNTATTDTMQAYDNALYRKVAWRLLPFLMACYIAAFLDRVNVGFAKLQMLDQLKFSDTIYGLGAGIFFI
GYFLFEVPSNVLMHRIGAKKTLARIMILWACISACMALTKTPTQFYILRFLLGAAEAGFYPGIILYLTYWFPSHRRGQVI
AVFMTAVPFAGILGGPLSGWIMESLHDHHGFAGWQWMFLIEAIPSIVLGLAVLWYLDDRITDARWLDTAEKNRLAHNIAA
EKTTKVDHVSLLTLFRDRRVIHMALICYCTVSSLSGLAFWIPSVIRSTGVVSLLDVGLLTAIPNACAVVSMILVCRHSDR
TRERRWHMVIPFLVGGAGLTLSTLFSHNPTFAVAMLSVAAAGCMVCSPLFWSLPTAFLEGRSAAAGIAAINSFAGLAAFA
SPYAIGWIKDLTGSTDWGMYFLASFTVIGALLVLRVPATLVNR

Sequences:

>Translated_443_residues
MHSAQTLRNPATNTATTDTMQAYDNALYRKVAWRLLPFLMACYIAAFLDRVNVGFAKLQMLDQLKFSDTIYGLGAGIFFI
GYFLFEVPSNVLMHRIGAKKTLARIMILWACISACMALTKTPTQFYILRFLLGAAEAGFYPGIILYLTYWFPSHRRGQVI
AVFMTAVPFAGILGGPLSGWIMESLHDHHGFAGWQWMFLIEAIPSIVLGLAVLWYLDDRITDARWLDTAEKNRLAHNIAA
EKTTKVDHVSLLTLFRDRRVIHMALICYCTVSSLSGLAFWIPSVIRSTGVVSLLDVGLLTAIPNACAVVSMILVCRHSDR
TRERRWHMVIPFLVGGAGLTLSTLFSHNPTFAVAMLSVAAAGCMVCSPLFWSLPTAFLEGRSAAAGIAAINSFAGLAAFA
SPYAIGWIKDLTGSTDWGMYFLASFTVIGALLVLRVPATLVNR
>Mature_443_residues
MHSAQTLRNPATNTATTDTMQAYDNALYRKVAWRLLPFLMACYIAAFLDRVNVGFAKLQMLDQLKFSDTIYGLGAGIFFI
GYFLFEVPSNVLMHRIGAKKTLARIMILWACISACMALTKTPTQFYILRFLLGAAEAGFYPGIILYLTYWFPSHRRGQVI
AVFMTAVPFAGILGGPLSGWIMESLHDHHGFAGWQWMFLIEAIPSIVLGLAVLWYLDDRITDARWLDTAEKNRLAHNIAA
EKTTKVDHVSLLTLFRDRRVIHMALICYCTVSSLSGLAFWIPSVIRSTGVVSLLDVGLLTAIPNACAVVSMILVCRHSDR
TRERRWHMVIPFLVGGAGLTLSTLFSHNPTFAVAMLSVAAAGCMVCSPLFWSLPTAFLEGRSAAAGIAAINSFAGLAAFA
SPYAIGWIKDLTGSTDWGMYFLASFTVIGALLVLRVPATLVNR

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Escherichia coli, GI87082071, Length=421, Percent_Identity=37.7672209026128, Blast_Score=266, Evalue=2e-72,
Organism=Escherichia coli, GI2367379, Length=401, Percent_Identity=23.4413965087282, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1789152, Length=410, Percent_Identity=21.4634146341463, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1789515, Length=421, Percent_Identity=22.8028503562945, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI87082320, Length=415, Percent_Identity=21.4457831325301, Blast_Score=69, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6322025, Length=194, Percent_Identity=30.9278350515464, Blast_Score=97, Evalue=7e-21,
Organism=Saccharomyces cerevisiae, GI6323032, Length=219, Percent_Identity=30.1369863013699, Blast_Score=85, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6321698, Length=380, Percent_Identity=22.3684210526316, Blast_Score=70, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6319250, Length=310, Percent_Identity=24.8387096774194, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6321502, Length=416, Percent_Identity=23.0769230769231, Blast_Score=64, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 48796; Mature: 48796

Theoretical pI: Translated: 9.20; Mature: 9.20

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHSAQTLRNPATNTATTDTMQAYDNALYRKVAWRLLPFLMACYIAAFLDRVNVGFAKLQM
CCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
LDQLKFSDTIYGLGAGIFFIGYFLFEVPSNVLMHRIGAKKTLARIMILWACISACMALTK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHC
TPTQFYILRFLLGAAEAGFYPGIILYLTYWFPSHRRGQVIAVFMTAVPFAGILGGPLSGW
CCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHCCCHHHH
IMESLHDHHGFAGWQWMFLIEAIPSIVLGLAVLWYLDDRITDARWLDTAEKNRLAHNIAA
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCHHHHHHHHHHHHH
EKTTKVDHVSLLTLFRDRRVIHMALICYCTVSSLSGLAFWIPSVIRSTGVVSLLDVGLLT
HHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
AIPNACAVVSMILVCRHSDRTRERRWHMVIPFLVGGAGLTLSTLFSHNPTFAVAMLSVAA
HCCHHHHHHHHHHHHHCCCHHHHHHHHEEEHHHHCCCCHHHHHHHCCCCHHHHHHHHHHH
AGCMVCSPLFWSLPTAFLEGRSAAAGIAAINSFAGLAAFASPYAIGWIKDLTGSTDWGMY
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCHHHH
FLASFTVIGALLVLRVPATLVNR
HHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]