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The map label for this gene is nahR [H]

Identifier: 73538169

GI number: 73538169

Start: 999062

End: 1000054

Strand: Reverse

Name: nahR [H]

Synonym: Reut_B4339

Alternate gene names: 73538169

Gene position: 1000054-999062 (Counterclockwise)

Preceding gene: 73538173

Following gene: 73538166

Centisome position: 36.68

GC content: 64.35

Gene sequence:

>993_bases
ATGCATACTGACGCATTCGACTACAACCTGCTGACGGTGTTCGACGCGATGCTGCGCGAGCGCAGCGTGACGCGCGCCGC
GGCGCAGCTGGGGCTTACGCAGAGCGCGATGAGCCACGCGCTGAACCGCCTGCGCGAGTTCTTCGACGATCCGTTGTTCG
TCAAGACCGCCGCTGGCATGACACCCACCATCAAGGCGGAAGCGCTGTCCGAAACCGTACTCGACGTCATGACGGCCATG
CGCACGCGCGTGCTGCCGCAGGCGAGCTTCGATCCCGCCACGATGCAGCGCACGTTCACGCTGTGCATGACCGACATGGG
CGAGCTGGTGTTCCTGCCACCGCTGATGAAACGGCTGCGCGTGGTGGCGCCTCACTGCAAGCTGCGAACGCTGCAGGTGC
CGGTGCCGCAGATCGAAGGGCTGCTGGCATCGGGCGATGCCGACCTGCTGCTAGGCTCGGTGCAGACGGCGCCGGAGTCG
CTGTTCCGGCAGCAGTTGTTCATGCATGGCTTCGTTACCATCGTGAGCACGAAGAACAGGCAGGTGCGCGACGCGCTGAC
GATCGAGCAGTTCGAGTCGATGCCGCACGTCACAGTGAGTCTCGCGGGCCGTACGAGCCCGTCGTACGACGCGGCATTCG
AAAGCCATGGGCTCAGGCGCAACATCTACCTGCATACGCCACACTTCCTCTCGATCCCGCTGCTGATGGAGCAGCAACCC
GAACTCATCGCGACTGTGCCCCAGGAACTCGCGAACGTCTTCAGCCGCTACGGCATCGTGCGCGTGGTGAAGCCTCCCGT
GGTGTTGCCGCCGTATGCGTTGAGCCAGTACTGGCATCCGCGCTTTCACCACGATCCGGCTATCGTCTGGCTGCGGCAGC
TGGTGAAGCAGACGTTCGACCGATATCCGGATACCGATGTGTCGGGCGATGCCATGCCCGTGCCGGCCCGCAAGAAAGGC
GCAACGGCTAAGCGGGGCGCCAGTTCGCGGTAG

Upstream 100 bases:

>100_bases
TCCTGTGTGTGGAACGCCCTCTGCGAGGCGTGTTGACAGGAGGTTAGGCAGCGCGCCAATATGCGTCAATCACATGCTGA
TTATAGAAGGAATGTATGTC

Downstream 100 bases:

>100_bases
CGTTCCCCAAGCCACGGCGAGGCGATGATCGAAGGGCGAGGCGCGCAGGTATCTGCCGGTCAGTGCCGGGGACTACCTGC
GCCAGCGAGTGCATGCGGTC

Product: regulatory protein LysR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MHTDAFDYNLLTVFDAMLRERSVTRAAAQLGLTQSAMSHALNRLREFFDDPLFVKTAAGMTPTIKAEALSETVLDVMTAM
RTRVLPQASFDPATMQRTFTLCMTDMGELVFLPPLMKRLRVVAPHCKLRTLQVPVPQIEGLLASGDADLLLGSVQTAPES
LFRQQLFMHGFVTIVSTKNRQVRDALTIEQFESMPHVTVSLAGRTSPSYDAAFESHGLRRNIYLHTPHFLSIPLLMEQQP
ELIATVPQELANVFSRYGIVRVVKPPVVLPPYALSQYWHPRFHHDPAIVWLRQLVKQTFDRYPDTDVSGDAMPVPARKKG
ATAKRGASSR

Sequences:

>Translated_330_residues
MHTDAFDYNLLTVFDAMLRERSVTRAAAQLGLTQSAMSHALNRLREFFDDPLFVKTAAGMTPTIKAEALSETVLDVMTAM
RTRVLPQASFDPATMQRTFTLCMTDMGELVFLPPLMKRLRVVAPHCKLRTLQVPVPQIEGLLASGDADLLLGSVQTAPES
LFRQQLFMHGFVTIVSTKNRQVRDALTIEQFESMPHVTVSLAGRTSPSYDAAFESHGLRRNIYLHTPHFLSIPLLMEQQP
ELIATVPQELANVFSRYGIVRVVKPPVVLPPYALSQYWHPRFHHDPAIVWLRQLVKQTFDRYPDTDVSGDAMPVPARKKG
ATAKRGASSR
>Mature_330_residues
MHTDAFDYNLLTVFDAMLRERSVTRAAAQLGLTQSAMSHALNRLREFFDDPLFVKTAAGMTPTIKAEALSETVLDVMTAM
RTRVLPQASFDPATMQRTFTLCMTDMGELVFLPPLMKRLRVVAPHCKLRTLQVPVPQIEGLLASGDADLLLGSVQTAPES
LFRQQLFMHGFVTIVSTKNRQVRDALTIEQFESMPHVTVSLAGRTSPSYDAAFESHGLRRNIYLHTPHFLSIPLLMEQQP
ELIATVPQELANVFSRYGIVRVVKPPVVLPPYALSQYWHPRFHHDPAIVWLRQLVKQTFDRYPDTDVSGDAMPVPARKKG
ATAKRGASSR

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=290, Percent_Identity=25.8620689655172, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1790147, Length=305, Percent_Identity=24.2622950819672, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI87081766, Length=251, Percent_Identity=27.0916334661355, Blast_Score=81, Evalue=8e-17,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 36994; Mature: 36994

Theoretical pI: Translated: 9.59; Mature: 9.59

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHTDAFDYNLLTVFDAMLRERSVTRAAAQLGLTQSAMSHALNRLREFFDDPLFVKTAAGM
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCEEEEECCCC
TPTIKAEALSETVLDVMTAMRTRVLPQASFDPATMQRTFTLCMTDMGELVFLPPLMKRLR
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCEEHHHHHHHHH
VVAPHCKLRTLQVPVPQIEGLLASGDADLLLGSVQTAPESLFRQQLFMHGFVTIVSTKNR
HHCCCCCEEEEECCCHHHHHHHCCCCHHHEECCHHHHHHHHHHHHHHHHHHHHEEECCCC
QVRDALTIEQFESMPHVTVSLAGRTSPSYDAAFESHGLRRNIYLHTPHFLSIPLLMEQQP
HHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHCCCEEEEEEECCCCEECCHHHCCCC
ELIATVPQELANVFSRYGIVRVVKPPVVLPPYALSQYWHPRFHHDPAIVWLRQLVKQTFD
HHHHHHHHHHHHHHHHCCEEEEECCCCCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
RYPDTDVSGDAMPVPARKKGATAKRGASSR
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MHTDAFDYNLLTVFDAMLRERSVTRAAAQLGLTQSAMSHALNRLREFFDDPLFVKTAAGM
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCEEEEECCCC
TPTIKAEALSETVLDVMTAMRTRVLPQASFDPATMQRTFTLCMTDMGELVFLPPLMKRLR
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCEEHHHHHHHHH
VVAPHCKLRTLQVPVPQIEGLLASGDADLLLGSVQTAPESLFRQQLFMHGFVTIVSTKNR
HHCCCCCEEEEECCCHHHHHHHCCCCHHHEECCHHHHHHHHHHHHHHHHHHHHEEECCCC
QVRDALTIEQFESMPHVTVSLAGRTSPSYDAAFESHGLRRNIYLHTPHFLSIPLLMEQQP
HHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHCCCEEEEEEECCCCEECCHHHCCCC
ELIATVPQELANVFSRYGIVRVVKPPVVLPPYALSQYWHPRFHHDPAIVWLRQLVKQTFD
HHHHHHHHHHHHHHHHCCEEEEECCCCCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
RYPDTDVSGDAMPVPARKKGATAKRGASSR
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]