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The map label for this gene is kdgK [H]

Identifier: 73537856

GI number: 73537856

Start: 663733

End: 664668

Strand: Direct

Name: kdgK [H]

Synonym: Reut_B4023

Alternate gene names: 73537856

Gene position: 663733-664668 (Clockwise)

Preceding gene: 73537855

Following gene: 73537857

Centisome position: 24.35

GC content: 67.2

Gene sequence:

>936_bases
ATGAGCATCGACATCCTGGCCTACGGCGAGCCGCTGGTGGAATTCAACCAGCAGCCCGACGACCCGACCCGCTACCTGCA
GGGCTTTGGCGGCGACACCTCGAACTTCTGCATTGCCGCGGCACGGCAGAGCGCTACCACTGGCTACATCAGCGCGGTGG
GCGCCGATAGCTTCGGCGAACGCCTGATGGCGCTATGGACGCGCGAGCGTGTGGACACGCGCCACGTGCGCGTCGATCCG
GTGGCGCCGACCGGCGTGTATTTCGTGAGCCATGACAACCATGGCCACCGCTTCGATTACCTGCGCGAAGGTTCTGCCGC
GAGCCGCTACCAACACGAACACCTGCCGCTGGGCGCTATTGCGCAGGCGAGCTTCCTGCATCTGTCGGGCATCAGCCTGG
CCATCAGCACGAGTGCCTGCGATGCGGGCCTGGCCGCGATGGAGCATGCGCGCAAGGCTGGCACCAAGGTGTCGCTCGAT
ACCAACCTGCGGCTGCGGCTGTGGTCGCTGGCGCGCGCGCGCGGCATCATGCGCGAGGCGTTTTCGCTGACCGACGTGTG
CCTGCCGAGCTGGGATGACATTACTGTGCTGACGGGACTCGACGACCGCGATGCCATCGTCGATTATCTGCTCGGCTGTG
GCATTGGCCTGGTCGCGCTGAAGCTTGGCGAGGAGGGCGCCTACGTCGCCACGCCGGAGTCGCGCACGCTGGTGCAGCCG
TTTGCCGTCAAGCCGGTGGATGCCACGGGTGCCGGCGACTGCTTCGGCGGCAGCTTCATCGCGCGGCTGGCTGCGGGTGC
CGATCCGTTCGAGGCGGCACGCTATGCCAACGTGGCCGCGGCGCTGTCTACCACCGGCTACGGTGCGGTGGCGCCGATTC
CTTCCGCGGAGACCGTGCTCGCCAGACTGGCGCAGTCGGTGTCCGTGATTGCCTGA

Upstream 100 bases:

>100_bases
CCCGTGCCTGACGTTCGACAAGTGGCGGCATATTCCCGTGCTCGACGGCGACATGCGCGTCATCGACATTGTCCAGACCT
TCTTCTGAGAAGAGCCCGCC

Downstream 100 bases:

>100_bases
TCAGATCCACACTTCCTTGTCCGCAACGAACCTGACTGCCATGCAACTTCAACCTTCCCCGCTGCTCGCGCGGCTGGCCA
ATGTGCCAGTCATTCCTGTG

Product: PfkB

Products: NA

Alternate protein names: 2-keto-3-deoxygluconokinase; 3-deoxy-2-oxo-D-gluconate kinase; KDG kinase [H]

Number of amino acids: Translated: 311; Mature: 310

Protein sequence:

>311_residues
MSIDILAYGEPLVEFNQQPDDPTRYLQGFGGDTSNFCIAAARQSATTGYISAVGADSFGERLMALWTRERVDTRHVRVDP
VAPTGVYFVSHDNHGHRFDYLREGSAASRYQHEHLPLGAIAQASFLHLSGISLAISTSACDAGLAAMEHARKAGTKVSLD
TNLRLRLWSLARARGIMREAFSLTDVCLPSWDDITVLTGLDDRDAIVDYLLGCGIGLVALKLGEEGAYVATPESRTLVQP
FAVKPVDATGAGDCFGGSFIARLAAGADPFEAARYANVAAALSTTGYGAVAPIPSAETVLARLAQSVSVIA

Sequences:

>Translated_311_residues
MSIDILAYGEPLVEFNQQPDDPTRYLQGFGGDTSNFCIAAARQSATTGYISAVGADSFGERLMALWTRERVDTRHVRVDP
VAPTGVYFVSHDNHGHRFDYLREGSAASRYQHEHLPLGAIAQASFLHLSGISLAISTSACDAGLAAMEHARKAGTKVSLD
TNLRLRLWSLARARGIMREAFSLTDVCLPSWDDITVLTGLDDRDAIVDYLLGCGIGLVALKLGEEGAYVATPESRTLVQP
FAVKPVDATGAGDCFGGSFIARLAAGADPFEAARYANVAAALSTTGYGAVAPIPSAETVLARLAQSVSVIA
>Mature_310_residues
SIDILAYGEPLVEFNQQPDDPTRYLQGFGGDTSNFCIAAARQSATTGYISAVGADSFGERLMALWTRERVDTRHVRVDPV
APTGVYFVSHDNHGHRFDYLREGSAASRYQHEHLPLGAIAQASFLHLSGISLAISTSACDAGLAAMEHARKAGTKVSLDT
NLRLRLWSLARARGIMREAFSLTDVCLPSWDDITVLTGLDDRDAIVDYLLGCGIGLVALKLGEEGAYVATPESRTLVQPF
AVKPVDATGAGDCFGGSFIARLAAGADPFEAARYANVAAALSTTGYGAVAPIPSAETVLARLAQSVSVIA

Specific function: Unknown

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=250, Percent_Identity=27.2, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI87082281, Length=308, Percent_Identity=31.1688311688312, Blast_Score=121, Evalue=5e-29,
Organism=Escherichia coli, GI87081971, Length=310, Percent_Identity=24.1935483870968, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1790193, Length=252, Percent_Identity=27.3809523809524, Blast_Score=69, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.45 [H]

Molecular weight: Translated: 32993; Mature: 32862

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIDILAYGEPLVEFNQQPDDPTRYLQGFGGDTSNFCIAAARQSATTGYISAVGADSFGE
CEEEEEECCCHHHHCCCCCCCHHHHHHHCCCCCCCEEEEECCCCCCCCEEEECCCCHHHH
RLMALWTRERVDTRHVRVDPVAPTGVYFVSHDNHGHRFDYLREGSAASRYQHEHLPLGAI
HHHHHHHHHCCCCCEEEECCCCCCEEEEEEECCCCCCCHHHHCCCHHHHHHHHCCCHHHH
AQASFLHLSGISLAISTSACDAGLAAMEHARKAGTKVSLDTNLRLRLWSLARARGIMREA
HHHHEEEECCCEEEEECCHHHHHHHHHHHHHHCCCEEEECCCCEEHHHHHHHHHHHHHHH
FSLTDVCLPSWDDITVLTGLDDRDAIVDYLLGCGIGLVALKLGEEGAYVATPESRTLVQP
HHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHCCCEEEEEEECCCCCEEECCCCCCEECC
FAVKPVDATGAGDCFGGSFIARLAAGADPFEAARYANVAAALSTTGYGAVAPIPSAETVL
CEECCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHH
ARLAQSVSVIA
HHHHHHHHHCC
>Mature Secondary Structure 
SIDILAYGEPLVEFNQQPDDPTRYLQGFGGDTSNFCIAAARQSATTGYISAVGADSFGE
EEEEEECCCHHHHCCCCCCCHHHHHHHCCCCCCCEEEEECCCCCCCCEEEECCCCHHHH
RLMALWTRERVDTRHVRVDPVAPTGVYFVSHDNHGHRFDYLREGSAASRYQHEHLPLGAI
HHHHHHHHHCCCCCEEEECCCCCCEEEEEEECCCCCCCHHHHCCCHHHHHHHHCCCHHHH
AQASFLHLSGISLAISTSACDAGLAAMEHARKAGTKVSLDTNLRLRLWSLARARGIMREA
HHHHEEEECCCEEEEECCHHHHHHHHHHHHHHCCCEEEECCCCEEHHHHHHHHHHHHHHH
FSLTDVCLPSWDDITVLTGLDDRDAIVDYLLGCGIGLVALKLGEEGAYVATPESRTLVQP
HHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHCCCEEEEEEECCCCCEEECCCCCCEECC
FAVKPVDATGAGDCFGGSFIARLAAGADPFEAARYANVAAALSTTGYGAVAPIPSAETVL
CEECCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHH
ARLAQSVSVIA
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8157608 [H]