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The map label for this gene is 73537855

Identifier: 73537855

GI number: 73537855

Start: 662452

End: 663720

Strand: Direct

Name: 73537855

Synonym: Reut_B4022

Alternate gene names: NA

Gene position: 662452-663720 (Clockwise)

Preceding gene: 73537849

Following gene: 73537856

Centisome position: 24.3

GC content: 65.64

Gene sequence:

>1269_bases
ATGCGTGAAATAAAGTACCAAGCCGGCACGATCGATCCGCTCAACAAGGCGCTGGGCCGACTGGAGGCGCCGATTGCCCC
CGAAAATGCTGGCCAGACGGGCTGGAACCTGCTGCGCGAAGAACTCAGCTTGCCGGCCGCAGTGCTTTATGAAGACCGTC
TGGCGCATAACCTGGAATGGATGAACCGCTTTATGGGCGAGTACGGTGTGCAGCTTGCGCCGCATGGCAAGACGACCATG
GCGCCCAAGTTGTTTGCGCGCCAGCTTGGCGCGGGTGCGTGGGGCATTACGCTCGCGACGGCGCACCAGACGGCAGCGGC
CTACGCGCACGGCGTGCGCCGCGTGCTGATGGCCAACCAGCTCGTGGGCCGCCGTAATATGGAAATCATTGCGGACCTGC
TGCGCGATCCCGGCTTCGAATTCTTCAGCCTGGTGGACTCCGCGGACCTCGTGGACCAGCTTGGCGCGTACTTTCGCGAG
CGTGGCCAGAAGCTGCAAGTGCTGCTGGAACTAGGCGTGGAGGGCGGCCGCACCGGCGTGCGCGATGCCGCGCAGCAGGC
GGACGTGCTGGCGGCACTGGCGCGCTGGCCCGACGCGTTGTCGCTGGCCGGCGTGGAGATCTATGAAGGCGTGCTGAAGG
AAGAGGCCGATATCCGGCGATTCCTGCAGCGCACGGTTGCCGTGACGCGCGAGATCGCGCAAGAGGGCCGTTTTGGCCGC
AGTCCGGTGGTCATGTCGGGCGCCGGTTCGGCGTGGTACGACGTGGTGGCCGAAGAGTTTGCGCGCACCGAGATTGGCAC
GCCGATCGAGATCGTGCTGCGTCCTGGCTGCTACCTGACCCATGACGTTGGCATCTACAAGGCCGCGCAGGAGCGCATCC
TCGCGAGCAACCCGGTAGCACAGAAGATGCGCGAAGGCCTGCTGCCGGCGTTGCAGCTGTGGGCGTACGTGCAGTCCGTG
CCGGAGCCTGAGCGCGCGATCATCGGCATGGGCAAGCGCGACGCGGCGTTCGACGCAGGCATGCCGACTCCCGCGGCAAT
CTACCGTCCAGGCAGCGATGCCCCGCTCGCCGTGCCCGCGCACTGGGAGGTCACCGGCATGATGGACCAGCACGCGTACC
TGCAGATCCGCGCGGGCGACGATATCCGGGTCGGCGACATGATCGCGTTCGACATCTCGCACCCGTGCCTGACGTTCGAC
AAGTGGCGGCATATTCCCGTGCTCGACGGCGACATGCGCGTCATCGACATTGTCCAGACCTTCTTCTGA

Upstream 100 bases:

>100_bases
CGCTCGGTGGATCGGCGTGTTACTTTATAACAAAGGATGAAATATCGTAATTTCAGGGATATCATTACGTCAATCAGATT
TTTTCAGGGTGATGACAGGC

Downstream 100 bases:

>100_bases
GAAGAGCCCGCCATGAGCATCGACATCCTGGCCTACGGCGAGCCGCTGGTGGAATTCAACCAGCAGCCCGACGACCCGAC
CCGCTACCTGCAGGGCTTTG

Product: D-serine deaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 422; Mature: 422

Protein sequence:

>422_residues
MREIKYQAGTIDPLNKALGRLEAPIAPENAGQTGWNLLREELSLPAAVLYEDRLAHNLEWMNRFMGEYGVQLAPHGKTTM
APKLFARQLGAGAWGITLATAHQTAAAYAHGVRRVLMANQLVGRRNMEIIADLLRDPGFEFFSLVDSADLVDQLGAYFRE
RGQKLQVLLELGVEGGRTGVRDAAQQADVLAALARWPDALSLAGVEIYEGVLKEEADIRRFLQRTVAVTREIAQEGRFGR
SPVVMSGAGSAWYDVVAEEFARTEIGTPIEIVLRPGCYLTHDVGIYKAAQERILASNPVAQKMREGLLPALQLWAYVQSV
PEPERAIIGMGKRDAAFDAGMPTPAAIYRPGSDAPLAVPAHWEVTGMMDQHAYLQIRAGDDIRVGDMIAFDISHPCLTFD
KWRHIPVLDGDMRVIDIVQTFF

Sequences:

>Translated_422_residues
MREIKYQAGTIDPLNKALGRLEAPIAPENAGQTGWNLLREELSLPAAVLYEDRLAHNLEWMNRFMGEYGVQLAPHGKTTM
APKLFARQLGAGAWGITLATAHQTAAAYAHGVRRVLMANQLVGRRNMEIIADLLRDPGFEFFSLVDSADLVDQLGAYFRE
RGQKLQVLLELGVEGGRTGVRDAAQQADVLAALARWPDALSLAGVEIYEGVLKEEADIRRFLQRTVAVTREIAQEGRFGR
SPVVMSGAGSAWYDVVAEEFARTEIGTPIEIVLRPGCYLTHDVGIYKAAQERILASNPVAQKMREGLLPALQLWAYVQSV
PEPERAIIGMGKRDAAFDAGMPTPAAIYRPGSDAPLAVPAHWEVTGMMDQHAYLQIRAGDDIRVGDMIAFDISHPCLTFD
KWRHIPVLDGDMRVIDIVQTFF
>Mature_422_residues
MREIKYQAGTIDPLNKALGRLEAPIAPENAGQTGWNLLREELSLPAAVLYEDRLAHNLEWMNRFMGEYGVQLAPHGKTTM
APKLFARQLGAGAWGITLATAHQTAAAYAHGVRRVLMANQLVGRRNMEIIADLLRDPGFEFFSLVDSADLVDQLGAYFRE
RGQKLQVLLELGVEGGRTGVRDAAQQADVLAALARWPDALSLAGVEIYEGVLKEEADIRRFLQRTVAVTREIAQEGRFGR
SPVVMSGAGSAWYDVVAEEFARTEIGTPIEIVLRPGCYLTHDVGIYKAAQERILASNPVAQKMREGLLPALQLWAYVQSV
PEPERAIIGMGKRDAAFDAGMPTPAAIYRPGSDAPLAVPAHWEVTGMMDQHAYLQIRAGDDIRVGDMIAFDISHPCLTFD
KWRHIPVLDGDMRVIDIVQTFF

Specific function: Catalyzes the reversible cleavage of D-theronine or D- allothreonine into glycine and acetaldehyde. Can also cleave D- beta-phenylserine, D-beta-hydroxy-alpha-aminovaleric acid, D-beta- 3,4-dihydroxyphenylserine and D-beta-3,4- methylenedioxyphenylserine

COG id: COG3616

COG function: function code E; Predicted amino acid aldolase or racemase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DSD1 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001608 [H]

Pfam domain/function: PF01168 Ala_racemase_N [H]

EC number: =4.1.2.42 [H]

Molecular weight: Translated: 46555; Mature: 46555

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: PS00228 TUBULIN_B_AUTOREG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREIKYQAGTIDPLNKALGRLEAPIAPENAGQTGWNLLREELSLPAAVLYEDRLAHNLEW
CCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHH
MNRFMGEYGVQLAPHGKTTMAPKLFARQLGAGAWGITLATAHQTAAAYAHGVRRVLMANQ
HHHHHHHHCCEECCCCCCHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHH
LVGRRNMEIIADLLRDPGFEFFSLVDSADLVDQLGAYFRERGQKLQVLLELGVEGGRTGV
HHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCCCCH
RDAAQQADVLAALARWPDALSLAGVEIYEGVLKEEADIRRFLQRTVAVTREIAQEGRFGR
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
SPVVMSGAGSAWYDVVAEEFARTEIGTPIEIVLRPGCYLTHDVGIYKAAQERILASNPVA
CCEEEECCCHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEECHHHHHHHHHHHHHCCHHH
QKMREGLLPALQLWAYVQSVPEPERAIIGMGKRDAAFDAGMPTPAAIYRPGSDAPLAVPA
HHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCCCCCCEEECCCCCCCEEECC
HWEVTGMMDQHAYLQIRAGDDIRVGDMIAFDISHPCLTFDKWRHIPVLDGDMRVIDIVQT
CEEEECEECCCEEEEEECCCCEEECCEEEEECCCCCCCHHCCCCCCEECCCHHHHHHHHH
FF
HC
>Mature Secondary Structure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HC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9642221 [H]