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The map label for this gene is arnA [H]

Identifier: 73537808

GI number: 73537808

Start: 612706

End: 613641

Strand: Reverse

Name: arnA [H]

Synonym: Reut_B3975

Alternate gene names: 73537808

Gene position: 613641-612706 (Counterclockwise)

Preceding gene: 73537809

Following gene: 73537807

Centisome position: 22.51

GC content: 68.48

Gene sequence:

>936_bases
ATGCGCGCAGTCGTCTTTGGCTACCACAACGTCGGCGACCGCTGCCTGCGCGTGCTGCACGCGCGCGGCGTCGATGTGGC
GCTGGTCGTCACGCACCGTGACCGCGCTGACGAGAACATCTGGTTCCGCCGCGTGGCGGATACGGCTACGGAACTCGGCA
TCCCGTTTATCTACGGCGAAGACCCGGCCGATCCGGCGATTGCCCAGGCCGTGCGCGACGCGAGCCCCGACGTGATCTTC
TCGTTCTACTACCGCTCGATGATCCCGGCGAGCGTGCTGGCGCTGGCCCCACAAGGCGCCTTCAACATGCACGGCTCGCT
GTTGCCTAAGTACCGCGGCCGCGTGCCGGTGAACTGGGCCGTTCTGCATGGCGAAACGGAAACCGGCGCCACGCTGCATG
CGATGGAAGCCAAACCGGACGCCGGCTACATCGTGGACCAGACCGCGGTGCCCATTCTGCCGGACGACACGGCCGGCGAA
GTCTTCGAGAAAGTCACCGTGGCCGCCGAGCAGACGCTGTGGCGCGCGCTGCCGGCCATGATGGCAGGCAACACGCCGCA
ACATCCGAACGTGCTGGCACAAGGCAGCTACTTCTCGGGTCGCCGTCCCGAGGATGGCCGCATCGACTGGAGCCGCCCCG
CGGCCGAGGTCTACAACCTAATCCGCGCGGTGGCGCCGCCCTACCCCGGCGCGTTCACCGACATCGCCGGCCAGCGCTTC
GTCGTTGCGCAGGCGCGCCGCCCGCTGTCCGCCCCGGCGCTGCCGACCGGCTGGCGCCCCGGCCTGCACGTGAGCCAGGG
CCAGATCATCGGCCTGTGCGGCGACGGCGGCCAGGTGCGCATCGACACTCTGCTTAATGCCGCGACATCCGCGCCGGTCA
CCGCGCAAGCGCTGGCACCCATTCTTACCGAACAGTCCAACGAGGAAAACCGATGA

Upstream 100 bases:

>100_bases
AATACGTGGGCCGCATCTACCAGGAAGTGCGCGACCGGCCGCGCTACCGTATCAAGGCCGTCCTTGAGGCGGAGCCTTCC
CGCCACCGGACGGAGGCATG

Downstream 100 bases:

>100_bases
AAAAGGTCCTGATTCTTGGCGTCAACGGCTTCATCGGCCACCACTTGACGCGCCGCATCCTGGAAACGACGTCGTGGGAG
GTCTACGGCATGGACATGTC

Product: putative formyltransferase

Products: NA

Alternate protein names: UDP-4-amino-4-deoxy-L-arabinose formyltransferase; ArnAFT; UDP-L-Ara4N formyltransferase; UDP-glucuronic acid oxidase, UDP-4-keto-hexauronic acid decarboxylating; ArnADH; UDP-GlcUA decarboxylase; UDP-glucuronic acid dehydrogenase [H]

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MRAVVFGYHNVGDRCLRVLHARGVDVALVVTHRDRADENIWFRRVADTATELGIPFIYGEDPADPAIAQAVRDASPDVIF
SFYYRSMIPASVLALAPQGAFNMHGSLLPKYRGRVPVNWAVLHGETETGATLHAMEAKPDAGYIVDQTAVPILPDDTAGE
VFEKVTVAAEQTLWRALPAMMAGNTPQHPNVLAQGSYFSGRRPEDGRIDWSRPAAEVYNLIRAVAPPYPGAFTDIAGQRF
VVAQARRPLSAPALPTGWRPGLHVSQGQIIGLCGDGGQVRIDTLLNAATSAPVTAQALAPILTEQSNEENR

Sequences:

>Translated_311_residues
MRAVVFGYHNVGDRCLRVLHARGVDVALVVTHRDRADENIWFRRVADTATELGIPFIYGEDPADPAIAQAVRDASPDVIF
SFYYRSMIPASVLALAPQGAFNMHGSLLPKYRGRVPVNWAVLHGETETGATLHAMEAKPDAGYIVDQTAVPILPDDTAGE
VFEKVTVAAEQTLWRALPAMMAGNTPQHPNVLAQGSYFSGRRPEDGRIDWSRPAAEVYNLIRAVAPPYPGAFTDIAGQRF
VVAQARRPLSAPALPTGWRPGLHVSQGQIIGLCGDGGQVRIDTLLNAATSAPVTAQALAPILTEQSNEENR
>Mature_311_residues
MRAVVFGYHNVGDRCLRVLHARGVDVALVVTHRDRADENIWFRRVADTATELGIPFIYGEDPADPAIAQAVRDASPDVIF
SFYYRSMIPASVLALAPQGAFNMHGSLLPKYRGRVPVNWAVLHGETETGATLHAMEAKPDAGYIVDQTAVPILPDDTAGE
VFEKVTVAAEQTLWRALPAMMAGNTPQHPNVLAQGSYFSGRRPEDGRIDWSRPAAEVYNLIRAVAPPYPGAFTDIAGQRF
VVAQARRPLSAPALPTGWRPGLHVSQGQIIGLCGDGGQVRIDTLLNAATSAPVTAQALAPILTEQSNEENR

Specific function: Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabin

COG id: COG0223

COG function: function code J; Methionyl-tRNA formyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the sugar epimerase family. UDP-glucuronic acid decarboxylase subfamily [H]

Homologues:

Organism=Homo sapiens, GI21614513, Length=196, Percent_Identity=25, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI238814322, Length=221, Percent_Identity=23.9819004524887, Blast_Score=69, Evalue=4e-12,
Organism=Escherichia coli, GI1788589, Length=277, Percent_Identity=42.2382671480144, Blast_Score=222, Evalue=2e-59,
Organism=Escherichia coli, GI1789683, Length=248, Percent_Identity=29.0322580645161, Blast_Score=101, Evalue=5e-23,
Organism=Drosophila melanogaster, GI45550868, Length=298, Percent_Identity=26.1744966442953, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI28571984, Length=238, Percent_Identity=26.890756302521, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR021168
- InterPro:   IPR001509
- InterPro:   IPR005793
- InterPro:   IPR002376
- InterPro:   IPR011034
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase; PF02911 Formyl_trans_C; PF00551 Formyl_trans_N [H]

EC number: =2.1.2.13; =1.1.1.305 [H]

Molecular weight: Translated: 33620; Mature: 33620

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAVVFGYHNVGDRCLRVLHARGVDVALVVTHRDRADENIWFRRVADTATELGIPFIYGE
CCEEEEECCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCEEECC
DPADPAIAQAVRDASPDVIFSFYYRSMIPASVLALAPQGAFNMHGSLLPKYRGRVPVNWA
CCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCCEEEE
VLHGETETGATLHAMEAKPDAGYIVDQTAVPILPDDTAGEVFEKVTVAAEQTLWRALPAM
EEECCCCCCCEEEEEECCCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
MAGNTPQHPNVLAQGSYFSGRRPEDGRIDWSRPAAEVYNLIRAVAPPYPGAFTDIAGQRF
HCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHCCCEE
VVAQARRPLSAPALPTGWRPGLHVSQGQIIGLCGDGGQVRIDTLLNAATSAPVTAQALAP
EEECCCCCCCCCCCCCCCCCCCEECCCCEEEEECCCCEEEHHHHHHHHCCCCCHHHHHHH
ILTEQSNEENR
HHHCCCCCCCC
>Mature Secondary Structure
MRAVVFGYHNVGDRCLRVLHARGVDVALVVTHRDRADENIWFRRVADTATELGIPFIYGE
CCEEEEECCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCEEECC
DPADPAIAQAVRDASPDVIFSFYYRSMIPASVLALAPQGAFNMHGSLLPKYRGRVPVNWA
CCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCCEEEE
VLHGETETGATLHAMEAKPDAGYIVDQTAVPILPDDTAGEVFEKVTVAAEQTLWRALPAM
EEECCCCCCCEEEEEECCCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
MAGNTPQHPNVLAQGSYFSGRRPEDGRIDWSRPAAEVYNLIRAVAPPYPGAFTDIAGQRF
HCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHCCCEE
VVAQARRPLSAPALPTGWRPGLHVSQGQIIGLCGDGGQVRIDTLLNAATSAPVTAQALAP
EEECCCCCCCCCCCCCCCCCCCEECCCCEEEEECCCCEEEHHHHHHHHCCCCCHHHHHHH
ILTEQSNEENR
HHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA