| Definition | Ralstonia eutropha JMP134 chromosome chromosome 2, complete sequence. |
|---|---|
| Accession | NC_007348 |
| Length | 2,726,152 |
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The map label for this gene is fabG [H]
Identifier: 73537409
GI number: 73537409
Start: 129465
End: 130268
Strand: Direct
Name: fabG [H]
Synonym: Reut_B3574
Alternate gene names: 73537409
Gene position: 129465-130268 (Clockwise)
Preceding gene: 73537408
Following gene: 73537410
Centisome position: 4.75
GC content: 66.29
Gene sequence:
>804_bases ATGTCCATGATTGAACTCGACGGCAAGGTTGCCGTCGTCACAGGCGGGTCCTCCGGCATCGGGCTGGCGACCGTCGAACT GCTGCTCGAAGCGGGCGCCGCCGTGGCCATGTGCGGCCGCGACGAAAGCCGCCTGCGCAGCGCCGAAGCGCAACTGCGCC AGAGGTTCCCCAACTGCCGGCTCTATGCCGCCACGTGCGACGTGCTCAAGCCCGAACAGGTCGCAGCGTTTGCCGCCAAC GTGCAAAGCACGCTCGGCAACGTCGACATGCTGGTCAACAACGCCGGCCAGGGCCGCGTGTCGACCTTTGCGAACACGGA AGATGCTGCGTGGATGGAAGAACTGCAGCTCAAGTTCTTCTCGGTGATCCACCCGACGCGCGCATTCCTGCCGCAGCTCG AGCAATCGGGGCAGGGCGCCATCGTCTGCGTGAACTCGCTGCTCGCGCAGCAGCCTGAGCCGCACATGGTCGCCACCTCC GCCGCGCGTGCCGGCGTGCTGAACCTGGTGCGTTCGATGGCCACCGAGTTCGCCCCGAAGGGTGTCCGCGTCAACGGCAT CCTGATCGGACTGGTCGAATCGGGCCAGTGGCGCCGCCGCTTCGATGCGCGCCCCGAAGAAGACCGCAACCTGGACTGGG CCGCATGGACCGCGCGCCTGGCCCAGCAGAAACATATTCCCCTTGGCCGCCTGGGCCTGCCCGTCGAGGCAGCCCGCGCC ATCCTGTTCCTTGCCTCGCCGTTGTCTTCGTACACCACGGGCAGCCATATTGATATCTCCGGAGGACACTCCCGTCATGC CTAA
Upstream 100 bases:
>100_bases TCAGGGAAACCGCGGGCGAATTGTCGCGCCTGCTGGACTACCGGCCCGCGCTGAAAAGCAGCGGCGGCAAGGTAGTGAAT CTGTATCGGGAGTGAGGACA
Downstream 100 bases:
>100_bases TCAACAACAGTACGAACAACAGCAAGTCACCGTGGGCTGTGCCATCACGGCGTTTCTCGAACAGTGCGGCGTCAAGGCAG CCTTTGGCGTGATCTCGATC
Product: short chain dehydrogenase
Products: NA
Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]
Number of amino acids: Translated: 267; Mature: 266
Protein sequence:
>267_residues MSMIELDGKVAVVTGGSSGIGLATVELLLEAGAAVAMCGRDESRLRSAEAQLRQRFPNCRLYAATCDVLKPEQVAAFAAN VQSTLGNVDMLVNNAGQGRVSTFANTEDAAWMEELQLKFFSVIHPTRAFLPQLEQSGQGAIVCVNSLLAQQPEPHMVATS AARAGVLNLVRSMATEFAPKGVRVNGILIGLVESGQWRRRFDARPEEDRNLDWAAWTARLAQQKHIPLGRLGLPVEAARA ILFLASPLSSYTTGSHIDISGGHSRHA
Sequences:
>Translated_267_residues MSMIELDGKVAVVTGGSSGIGLATVELLLEAGAAVAMCGRDESRLRSAEAQLRQRFPNCRLYAATCDVLKPEQVAAFAAN VQSTLGNVDMLVNNAGQGRVSTFANTEDAAWMEELQLKFFSVIHPTRAFLPQLEQSGQGAIVCVNSLLAQQPEPHMVATS AARAGVLNLVRSMATEFAPKGVRVNGILIGLVESGQWRRRFDARPEEDRNLDWAAWTARLAQQKHIPLGRLGLPVEAARA ILFLASPLSSYTTGSHIDISGGHSRHA >Mature_266_residues SMIELDGKVAVVTGGSSGIGLATVELLLEAGAAVAMCGRDESRLRSAEAQLRQRFPNCRLYAATCDVLKPEQVAAFAANV QSTLGNVDMLVNNAGQGRVSTFANTEDAAWMEELQLKFFSVIHPTRAFLPQLEQSGQGAIVCVNSLLAQQPEPHMVATSA ARAGVLNLVRSMATEFAPKGVRVNGILIGLVESGQWRRRFDARPEEDRNLDWAAWTARLAQQKHIPLGRLGLPVEAARAI LFLASPLSSYTTGSHIDISGGHSRHA
Specific function: 7-Alpha-Dehydroxylation Of Cholic Acid, Yielding Deoxycholic Acid And Lithocholic Acid, Respectively. Highest Affinity With Taurochenodeoxycholic Acid. [C]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI19923817, Length=266, Percent_Identity=30.0751879699248, Blast_Score=125, Evalue=3e-29, Organism=Homo sapiens, GI32483357, Length=258, Percent_Identity=27.1317829457364, Blast_Score=100, Evalue=1e-21, Organism=Homo sapiens, GI5031737, Length=261, Percent_Identity=28.735632183908, Blast_Score=95, Evalue=8e-20, Organism=Homo sapiens, GI40254992, Length=254, Percent_Identity=28.740157480315, Blast_Score=92, Evalue=6e-19, Organism=Homo sapiens, GI66933014, Length=265, Percent_Identity=30.9433962264151, Blast_Score=89, Evalue=3e-18, Organism=Homo sapiens, GI10190704, Length=257, Percent_Identity=26.8482490272374, Blast_Score=87, Evalue=1e-17, Organism=Homo sapiens, GI126723750, Length=261, Percent_Identity=25.2873563218391, Blast_Score=84, Evalue=9e-17, Organism=Homo sapiens, GI59889578, Length=239, Percent_Identity=28.4518828451883, Blast_Score=81, Evalue=1e-15, Organism=Homo sapiens, GI33667109, Length=190, Percent_Identity=30.5263157894737, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI31542939, Length=196, Percent_Identity=31.6326530612245, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI126723191, Length=187, Percent_Identity=27.807486631016, Blast_Score=75, Evalue=5e-14, Organism=Homo sapiens, GI20149619, Length=162, Percent_Identity=29.0123456790123, Blast_Score=75, Evalue=9e-14, Organism=Homo sapiens, GI4503301, Length=259, Percent_Identity=25.8687258687259, Blast_Score=71, Evalue=8e-13, Organism=Homo sapiens, GI4503817, Length=183, Percent_Identity=28.4153005464481, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI4758504, Length=248, Percent_Identity=31.0483870967742, Blast_Score=69, Evalue=3e-12, Organism=Homo sapiens, GI224922801, Length=174, Percent_Identity=31.6091954022989, Blast_Score=69, Evalue=4e-12, Organism=Homo sapiens, GI7705925, Length=262, Percent_Identity=27.8625954198473, Blast_Score=67, Evalue=1e-11, Organism=Homo sapiens, GI31543615, Length=145, Percent_Identity=28.2758620689655, Blast_Score=67, Evalue=1e-11, Organism=Homo sapiens, GI15277342, Length=270, Percent_Identity=25.5555555555556, Blast_Score=65, Evalue=5e-11, Organism=Escherichia coli, GI1787905, Length=259, Percent_Identity=30.5019305019305, Blast_Score=119, Evalue=2e-28, Organism=Escherichia coli, GI1787335, Length=259, Percent_Identity=28.957528957529, Blast_Score=104, Evalue=8e-24, Organism=Escherichia coli, GI87082100, Length=264, Percent_Identity=29.9242424242424, Blast_Score=97, Evalue=1e-21, Organism=Escherichia coli, GI1789208, Length=263, Percent_Identity=28.8973384030418, Blast_Score=92, Evalue=4e-20, Organism=Escherichia coli, GI1786812, Length=261, Percent_Identity=29.1187739463602, Blast_Score=85, Evalue=5e-18, Organism=Escherichia coli, GI1789057, Length=257, Percent_Identity=24.9027237354086, Blast_Score=77, Evalue=1e-15, Organism=Escherichia coli, GI1790717, Length=261, Percent_Identity=25.2873563218391, Blast_Score=77, Evalue=1e-15, Organism=Escherichia coli, GI1789378, Length=262, Percent_Identity=26.7175572519084, Blast_Score=73, Evalue=2e-14, Organism=Escherichia coli, GI87082160, Length=269, Percent_Identity=28.2527881040892, Blast_Score=72, Evalue=4e-14, Organism=Escherichia coli, GI1788459, Length=257, Percent_Identity=24.5136186770428, Blast_Score=62, Evalue=3e-11, Organism=Escherichia coli, GI1787820, Length=186, Percent_Identity=26.8817204301075, Blast_Score=61, Evalue=9e-11, Organism=Caenorhabditis elegans, GI25147288, Length=261, Percent_Identity=31.0344827586207, Blast_Score=108, Evalue=4e-24, Organism=Caenorhabditis elegans, GI17560676, Length=262, Percent_Identity=29.7709923664122, Blast_Score=105, Evalue=3e-23, Organism=Caenorhabditis elegans, GI17561402, Length=271, Percent_Identity=27.6752767527675, Blast_Score=102, Evalue=1e-22, Organism=Caenorhabditis elegans, GI17560150, Length=268, Percent_Identity=30.5970149253731, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI17562990, Length=267, Percent_Identity=29.5880149812734, Blast_Score=98, Evalue=4e-21, Organism=Caenorhabditis elegans, GI17531453, Length=271, Percent_Identity=28.7822878228782, Blast_Score=97, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17562906, Length=271, Percent_Identity=30.2583025830258, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI17562904, Length=269, Percent_Identity=30.1115241635688, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI72000259, Length=287, Percent_Identity=31.3588850174216, Blast_Score=96, Evalue=3e-20, Organism=Caenorhabditis elegans, GI17560332, Length=272, Percent_Identity=30.1470588235294, Blast_Score=94, Evalue=6e-20, Organism=Caenorhabditis elegans, GI17538480, Length=273, Percent_Identity=30.7692307692308, Blast_Score=94, Evalue=6e-20, Organism=Caenorhabditis elegans, GI71994604, Length=256, Percent_Identity=30.859375, Blast_Score=94, Evalue=8e-20, Organism=Caenorhabditis elegans, GI17565030, Length=265, Percent_Identity=30.9433962264151, Blast_Score=93, Evalue=1e-19, Organism=Caenorhabditis elegans, GI17559104, Length=274, Percent_Identity=31.021897810219, Blast_Score=92, Evalue=2e-19, Organism=Caenorhabditis elegans, GI71994600, Length=256, Percent_Identity=28.515625, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI17562910, Length=264, Percent_Identity=31.0606060606061, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI17555706, Length=258, Percent_Identity=29.4573643410853, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17538486, Length=276, Percent_Identity=29.7101449275362, Blast_Score=88, Evalue=6e-18, Organism=Caenorhabditis elegans, GI193204405, Length=271, Percent_Identity=28.7822878228782, Blast_Score=87, Evalue=8e-18, Organism=Caenorhabditis elegans, GI17560220, Length=271, Percent_Identity=28.0442804428044, Blast_Score=87, Evalue=8e-18, Organism=Caenorhabditis elegans, GI17536025, Length=272, Percent_Identity=27.5735294117647, Blast_Score=85, Evalue=4e-17, Organism=Caenorhabditis elegans, GI17561272, Length=267, Percent_Identity=29.5880149812734, Blast_Score=84, Evalue=5e-17, Organism=Caenorhabditis elegans, GI17551412, Length=267, Percent_Identity=29.5880149812734, Blast_Score=82, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17544670, Length=269, Percent_Identity=28.996282527881, Blast_Score=82, Evalue=3e-16, Organism=Caenorhabditis elegans, GI17562908, Length=272, Percent_Identity=27.5735294117647, Blast_Score=82, Evalue=3e-16, Organism=Caenorhabditis elegans, GI17563726, Length=273, Percent_Identity=27.8388278388278, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17536651, Length=273, Percent_Identity=24.9084249084249, Blast_Score=73, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17567345, Length=183, Percent_Identity=24.0437158469945, Blast_Score=67, Evalue=1e-11, Organism=Caenorhabditis elegans, GI17508651, Length=263, Percent_Identity=29.277566539924, Blast_Score=64, Evalue=9e-11, Organism=Saccharomyces cerevisiae, GI6324126, Length=259, Percent_Identity=27.7992277992278, Blast_Score=102, Evalue=9e-23, Organism=Saccharomyces cerevisiae, GI6323882, Length=213, Percent_Identity=28.6384976525822, Blast_Score=81, Evalue=2e-16, Organism=Saccharomyces cerevisiae, GI6322067, Length=194, Percent_Identity=31.4432989690722, Blast_Score=75, Evalue=9e-15, Organism=Drosophila melanogaster, GI21355319, Length=262, Percent_Identity=30.5343511450382, Blast_Score=108, Evalue=4e-24, Organism=Drosophila melanogaster, GI23397609, Length=262, Percent_Identity=32.0610687022901, Blast_Score=102, Evalue=2e-22, Organism=Drosophila melanogaster, GI21357041, Length=266, Percent_Identity=31.9548872180451, Blast_Score=100, Evalue=2e-21, Organism=Drosophila melanogaster, GI24644339, Length=261, Percent_Identity=31.0344827586207, Blast_Score=94, Evalue=1e-19, Organism=Drosophila melanogaster, GI24644337, Length=261, Percent_Identity=31.8007662835249, Blast_Score=93, Evalue=2e-19, Organism=Drosophila melanogaster, GI24639444, Length=265, Percent_Identity=30.9433962264151, Blast_Score=89, Evalue=4e-18, Organism=Drosophila melanogaster, GI28571526, Length=266, Percent_Identity=29.6992481203008, Blast_Score=89, Evalue=4e-18, Organism=Drosophila melanogaster, GI116007236, Length=199, Percent_Identity=34.6733668341709, Blast_Score=80, Evalue=1e-15, Organism=Drosophila melanogaster, GI24643142, Length=260, Percent_Identity=29.6153846153846, Blast_Score=78, Evalue=5e-15, Organism=Drosophila melanogaster, GI21355631, Length=173, Percent_Identity=31.2138728323699, Blast_Score=78, Evalue=6e-15, Organism=Drosophila melanogaster, GI116007238, Length=202, Percent_Identity=33.1683168316832, Blast_Score=77, Evalue=1e-14, Organism=Drosophila melanogaster, GI221331218, Length=172, Percent_Identity=31.9767441860465, Blast_Score=70, Evalue=2e-12, Organism=Drosophila melanogaster, GI24665243, Length=172, Percent_Identity=31.9767441860465, Blast_Score=70, Evalue=2e-12, Organism=Drosophila melanogaster, GI281364892, Length=183, Percent_Identity=28.9617486338798, Blast_Score=69, Evalue=3e-12, Organism=Drosophila melanogaster, GI21358495, Length=195, Percent_Identity=24.6153846153846, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI221331216, Length=172, Percent_Identity=31.3953488372093, Blast_Score=66, Evalue=3e-11, Organism=Drosophila melanogaster, GI24665247, Length=172, Percent_Identity=31.3953488372093, Blast_Score=65, Evalue=3e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011284 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.100 [H]
Molecular weight: Translated: 28685; Mature: 28554
Theoretical pI: Translated: 7.55; Mature: 7.55
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.5 %Cys (Translated Protein) 2.6 %Met (Translated Protein) 4.1 %Cys+Met (Translated Protein) 1.5 %Cys (Mature Protein) 2.3 %Met (Mature Protein) 3.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSMIELDGKVAVVTGGSSGIGLATVELLLEAGAAVAMCGRDESRLRSAEAQLRQRFPNCR CCEEEECCEEEEEECCCCCCHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHCCCCE LYAATCDVLKPEQVAAFAANVQSTLGNVDMLVNNAGQGRVSTFANTEDAAWMEELQLKFF EEEEECCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCEEECCCCCHHHHHHHHHHHHH SVIHPTRAFLPQLEQSGQGAIVCVNSLLAQQPEPHMVATSAARAGVLNLVRSMATEFAPK HHHHHHHHHHHHHHHCCCCEEEEEHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHCCC GVRVNGILIGLVESGQWRRRFDARPEEDRNLDWAAWTARLAQQKHIPLGRLGLPVEAARA CEEEEEEEEEEECCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHH ILFLASPLSSYTTGSHIDISGGHSRHA HHHHHCCHHHCCCCCEEEECCCCCCCC >Mature Secondary Structure SMIELDGKVAVVTGGSSGIGLATVELLLEAGAAVAMCGRDESRLRSAEAQLRQRFPNCR CEEEECCEEEEEECCCCCCHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHCCCCE LYAATCDVLKPEQVAAFAANVQSTLGNVDMLVNNAGQGRVSTFANTEDAAWMEELQLKFF EEEEECCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCEEECCCCCHHHHHHHHHHHHH SVIHPTRAFLPQLEQSGQGAIVCVNSLLAQQPEPHMVATSAARAGVLNLVRSMATEFAPK HHHHHHHHHHHHHHHCCCCEEEEEHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHCCC GVRVNGILIGLVESGQWRRRFDARPEEDRNLDWAAWTARLAQQKHIPLGRLGLPVEAARA CEEEEEEEEEEECCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHH ILFLASPLSSYTTGSHIDISGGHSRHA HHHHHCCHHHCCCCCEEEECCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 10952301 [H]