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The map label for this gene is tdk2 [H]

Identifier: 71910675

GI number: 71910675

Start: 852567

End: 853136

Strand: Direct

Name: tdk2 [H]

Synonym: M5005_Spy_0862

Alternate gene names: 71910675

Gene position: 852567-853136 (Clockwise)

Preceding gene: 71910672

Following gene: 71910676

Centisome position: 46.37

GC content: 35.09

Gene sequence:

>570_bases
TTGGCTCAACTCTATTATAAATATGGGACAATGAATTCTGGTAAAACCATTGAAATTTTAAAAGTTGCTCATAACTATGA
AGAACAAGGCAAACCTGTTGTCATTATGACAAGTGCTCTTGATACACGTGATGGTTTTGGCATCGTCTCAAGCCGTATTG
GTATGCGACGAGAAGCTATCCCCATTTCAAATGACATGGATATTTTCACATTTATTGCCCAATTGGAGGAAAAACCTTAT
TGTGTCCTGATTGACGAAAGCCAATTTTTAAGCAAGCAAAATGTTTATGATTTGGCGCGTGTGGTGGATGAGCTAAATGT
TCCTGTCATGGCTTTTGGTTTGAAAAATGATTTCCAAAACAATCTTTTTGAAGGTTCAAAACATTTGCTATTATTGGCCG
ATAAGATTGATGAAATCAAAACAATTTGCCAATACTGTAGTAAGAAAGCAACCATGGTTTTAAGGACAGAAAACGGAAAA
CCTGTCTATGAAGGTGATCAGATACAAATTGGTGGTAATGAAACATATATCCCAGTTTGTCGAAAACATTATTTTAATCC
AGATATTTAA

Upstream 100 bases:

>100_bases
ATAATGCTGTGAAAAAGTATACACTGTTTTCAATGGCTGGGAAAACTTCAGCCTTTGTGGTAAAATAGGTAGAATACTAT
AGAAAGTAGGATTTTCCGCT

Downstream 100 bases:

>100_bases
AAGGTAATCGGTTTTAAAGGAGATACAAAGAAAAATGAATATTTATGATCAATTGCAGGCAGTTGAAGATCGTTATGAAG
AGTTAGGTGAGTTACTTAGT

Product: thymidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 189; Mature: 188

Protein sequence:

>189_residues
MAQLYYKYGTMNSGKTIEILKVAHNYEEQGKPVVIMTSALDTRDGFGIVSSRIGMRREAIPISNDMDIFTFIAQLEEKPY
CVLIDESQFLSKQNVYDLARVVDELNVPVMAFGLKNDFQNNLFEGSKHLLLLADKIDEIKTICQYCSKKATMVLRTENGK
PVYEGDQIQIGGNETYIPVCRKHYFNPDI

Sequences:

>Translated_189_residues
MAQLYYKYGTMNSGKTIEILKVAHNYEEQGKPVVIMTSALDTRDGFGIVSSRIGMRREAIPISNDMDIFTFIAQLEEKPY
CVLIDESQFLSKQNVYDLARVVDELNVPVMAFGLKNDFQNNLFEGSKHLLLLADKIDEIKTICQYCSKKATMVLRTENGK
PVYEGDQIQIGGNETYIPVCRKHYFNPDI
>Mature_188_residues
AQLYYKYGTMNSGKTIEILKVAHNYEEQGKPVVIMTSALDTRDGFGIVSSRIGMRREAIPISNDMDIFTFIAQLEEKPYC
VLIDESQFLSKQNVYDLARVVDELNVPVMAFGLKNDFQNNLFEGSKHLLLLADKIDEIKTICQYCSKKATMVLRTENGKP
VYEGDQIQIGGNETYIPVCRKHYFNPDI

Specific function: Phosphorylates Both Thymidine And Deoxyuridine. [C]

COG id: COG1435

COG function: function code F; Thymidine kinase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thymidine kinase family [H]

Homologues:

Organism=Escherichia coli, GI1787490, Length=187, Percent_Identity=48.6631016042781, Blast_Score=189, Evalue=1e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001267
- InterPro:   IPR020633
- InterPro:   IPR020634 [H]

Pfam domain/function: PF00265 TK [H]

EC number: =2.7.1.21 [H]

Molecular weight: Translated: 21533; Mature: 21402

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: PS00603 TK_CELLULAR_TYPE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQLYYKYGTMNSGKTIEILKVAHNYEEQGKPVVIMTSALDTRDGFGIVSSRIGMRREAI
CCEEEEEECCCCCCCEEEEEEEECCHHHCCCCEEEEEECCCCCCCCHHHHHHCCCCCCCC
PISNDMDIFTFIAQLEEKPYCVLIDESQFLSKQNVYDLARVVDELNVPVMAFGLKNDFQN
CCCCCCHHHHHHHHHCCCCEEEEECCHHHHHHCCHHHHHHHHHHCCCCEEEEECCCHHHH
NLFEGSKHLLLLADKIDEIKTICQYCSKKATMVLRTENGKPVYEGDQIQIGGNETYIPVC
HHHCCCCEEEEEEHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCEEEECCCCEEEHHH
RKHYFNPDI
HHCCCCCCC
>Mature Secondary Structure 
AQLYYKYGTMNSGKTIEILKVAHNYEEQGKPVVIMTSALDTRDGFGIVSSRIGMRREAI
CEEEEEECCCCCCCEEEEEEEECCHHHCCCCEEEEEECCCCCCCCHHHHHHCCCCCCCC
PISNDMDIFTFIAQLEEKPYCVLIDESQFLSKQNVYDLARVVDELNVPVMAFGLKNDFQN
CCCCCCHHHHHHHHHCCCCEEEEECCHHHHHHCCHHHHHHHHHHCCCCEEEEECCCHHHH
NLFEGSKHLLLLADKIDEIKTICQYCSKKATMVLRTENGKPVYEGDQIQIGGNETYIPVC
HHHCCCCEEEEEEHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCEEEECCCCEEEHHH
RKHYFNPDI
HHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA