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The map label for this gene is hldD [H]

Identifier: 71892371

GI number: 71892371

Start: 752038

End: 753000

Strand: Direct

Name: hldD [H]

Synonym: BPEN_630

Alternate gene names: 71892371

Gene position: 752038-753000 (Clockwise)

Preceding gene: 71892364

Following gene: 71892372

Centisome position: 95.0

GC content: 28.66

Gene sequence:

>963_bases
ATGATTGTGGTCACTGGCGGAGCAGGGTTTATAGGTTGCAATATTATTAAGGCTTTAAATAAAATTGCATACAAAAATAT
TTTAGTGGTAGATAATTTAAAAAATGGAAAAAAATATAACAATCTGAAAAGTTTGTATATTTCGGACTACATGGATAAAA
ATTGCTTTATCAAAAATATACTGAATAATCCTGTTAATTCTTATATTAAGGATATAGATGTAGTGTTTCATGAAGGAGCC
TGCTCTTCCACTACTGAATGGGATGGCAAGTATATGATGGAGAATAATTATCAATATTCTAAAGATCTATTATTTTATTG
TCTTAAAAACAAAATTCCTTTTATATATGCTTCCTCTGCGTCAGTATATGGTAAAGATACCAGAATGCTTCTTCATCCCC
AGGCATATGAACAACCCATGAATATATACAGTTATTCCAAATTTTTATTTGATCAATATGTGCGTACTATATTGCCAAAA
GTTACATCTCAGGTTTGTGGATTAAGATACTTTAATGTTTATGGCCCCTATGAAGCACATAAAGGTAGTATGGCTAGTAT
AGTATTTCAATTATATCAACAAATTACCAGTAAAAAACACCCAACACTGTTTATTGGAAGTAAACAGTTAAACAGGGATT
TTATATATATTGAAGATATAGTTGATATAAATCTTTGGGCCTGGAATAATAAAATATCTGGAATTTTTGATTGTGGAACA
GGTAAATCTAAATCATTTGAGTTCATTGCTAATATCGTGTTAAGTTTTTTTAATCAAAACATAACCATTAAATATATTTC
TATGCCAAAAAAAATACGTGATCATTATCAAATATTTACTCAGGCAAATATCTCTCAGTTAAGAACGACAGGTTATTGTA
AGGAATTTACTAACCTTAATCAAGGTATATGTCGCTATTTAAATTGGTTGTCATACAACAATGTTAATCATTGTAATAAT
TAA

Upstream 100 bases:

>100_bases
AAATATTAAAACGCTATATTTCATGATGTTGTGTTATATAAAATAATTTAAATTATTGTATTAATTGTATTTAAGTATAC
ATGTAATTATGTGAGAAAGT

Downstream 100 bases:

>100_bases
GTGAATAAAATTTTCATTGTGAAAATATTAGTTATTAGTCCTTCATGGATTGGCGATACCGTGATATCACATAGTATGTA
TCGATTGTTGATTAAGAAAT

Product: ADP-L-glycero-D-mannoheptose-6-epimerase

Products: NA

Alternate protein names: ADP-L-glycero-beta-D-manno-heptose-6-epimerase; ADP-glyceromanno-heptose 6-epimerase; ADP-hep 6-epimerase; AGME [H]

Number of amino acids: Translated: 320; Mature: 320

Protein sequence:

>320_residues
MIVVTGGAGFIGCNIIKALNKIAYKNILVVDNLKNGKKYNNLKSLYISDYMDKNCFIKNILNNPVNSYIKDIDVVFHEGA
CSSTTEWDGKYMMENNYQYSKDLLFYCLKNKIPFIYASSASVYGKDTRMLLHPQAYEQPMNIYSYSKFLFDQYVRTILPK
VTSQVCGLRYFNVYGPYEAHKGSMASIVFQLYQQITSKKHPTLFIGSKQLNRDFIYIEDIVDINLWAWNNKISGIFDCGT
GKSKSFEFIANIVLSFFNQNITIKYISMPKKIRDHYQIFTQANISQLRTTGYCKEFTNLNQGICRYLNWLSYNNVNHCNN

Sequences:

>Translated_320_residues
MIVVTGGAGFIGCNIIKALNKIAYKNILVVDNLKNGKKYNNLKSLYISDYMDKNCFIKNILNNPVNSYIKDIDVVFHEGA
CSSTTEWDGKYMMENNYQYSKDLLFYCLKNKIPFIYASSASVYGKDTRMLLHPQAYEQPMNIYSYSKFLFDQYVRTILPK
VTSQVCGLRYFNVYGPYEAHKGSMASIVFQLYQQITSKKHPTLFIGSKQLNRDFIYIEDIVDINLWAWNNKISGIFDCGT
GKSKSFEFIANIVLSFFNQNITIKYISMPKKIRDHYQIFTQANISQLRTTGYCKEFTNLNQGICRYLNWLSYNNVNHCNN
>Mature_320_residues
MIVVTGGAGFIGCNIIKALNKIAYKNILVVDNLKNGKKYNNLKSLYISDYMDKNCFIKNILNNPVNSYIKDIDVVFHEGA
CSSTTEWDGKYMMENNYQYSKDLLFYCLKNKIPFIYASSASVYGKDTRMLLHPQAYEQPMNIYSYSKFLFDQYVRTILPK
VTSQVCGLRYFNVYGPYEAHKGSMASIVFQLYQQITSKKHPTLFIGSKQLNRDFIYIEDIVDINLWAWNNKISGIFDCGT
GKSKSFEFIANIVLSFFNQNITIKYISMPKKIRDHYQIFTQANISQLRTTGYCKEFTNLNQGICRYLNWLSYNNVNHCNN

Specific function: Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose [H]

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family. HldD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790049, Length=310, Percent_Identity=53.8709677419355, Blast_Score=369, Evalue=1e-103,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR011912
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.20 [H]

Molecular weight: Translated: 37119; Mature: 37119

Theoretical pI: Translated: 9.31; Mature: 9.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVVTGGAGFIGCNIIKALNKIAYKNILVVDNLKNGKKYNNLKSLYISDYMDKNCFIKNI
CEEEECCCCHHHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHCCCCHHHHHH
LNNPVNSYIKDIDVVFHEGACSSTTEWDGKYMMENNYQYSKDLLFYCLKNKIPFIYASSA
HCCHHHHHHHHHHHEEECCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHCCCCEEEECCC
SVYGKDTRMLLHPQAYEQPMNIYSYSKFLFDQYVRTILPKVTSQVCGLRYFNVYGPYEAH
CCCCCCCEEEECCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCCCCC
KGSMASIVFQLYQQITSKKHPTLFIGSKQLNRDFIYIEDIVDINLWAWNNKISGIFDCGT
CCHHHHHHHHHHHHHHCCCCCEEEEECHHCCCCEEEEEEEEEEEEEEECCCCCEEEECCC
GKSKSFEFIANIVLSFFNQNITIKYISMPKKIRDHYQIFTQANISQLRTTGYCKEFTNLN
CCCCHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCC
QGICRYLNWLSYNNVNHCNN
HHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MIVVTGGAGFIGCNIIKALNKIAYKNILVVDNLKNGKKYNNLKSLYISDYMDKNCFIKNI
CEEEECCCCHHHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHCCCCHHHHHH
LNNPVNSYIKDIDVVFHEGACSSTTEWDGKYMMENNYQYSKDLLFYCLKNKIPFIYASSA
HCCHHHHHHHHHHHEEECCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHCCCCEEEECCC
SVYGKDTRMLLHPQAYEQPMNIYSYSKFLFDQYVRTILPKVTSQVCGLRYFNVYGPYEAH
CCCCCCCEEEECCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCCCCC
KGSMASIVFQLYQQITSKKHPTLFIGSKQLNRDFIYIEDIVDINLWAWNNKISGIFDCGT
CCHHHHHHHHHHHHHHCCCCCEEEEECHHCCCCEEEEEEEEEEEEEEECCCCCEEEECCC
GKSKSFEFIANIVLSFFNQNITIKYISMPKKIRDHYQIFTQANISQLRTTGYCKEFTNLN
CCCCHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCC
QGICRYLNWLSYNNVNHCNN
HHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA