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The map label for this gene is ppnK

Identifier: 71892318

GI number: 71892318

Start: 675593

End: 676486

Strand: Direct

Name: ppnK

Synonym: BPEN_565

Alternate gene names: 71892318

Gene position: 675593-676486 (Clockwise)

Preceding gene: 71892316

Following gene: 71892319

Centisome position: 85.34

GC content: 30.87

Gene sequence:

>894_bases
ATGACTTCTTCTATTTTTCGTACTATTGGTATTATCGGATATTCTCGTCATCCGAAAGCTGTGCATACATATGATATTTT
ATATCATTGGTTATATAGTAAAGGGATTACAGTAATTATCGAACATCATGCTGCTAGTTTATTAAATGTACAAAAAGCAG
TTGTAGGTGATTTAAATGATATAGGAAATTACGCAGACTTAGCTATAGTTATAGGTGGAGATGGCAATATGTTAAGAGCC
GCGAATATTTTAGCACAACACGATATTAAAGTTATTGGGATCAATCGTGGAACTCTTGGTTTTCTTACTGATTTAGACCC
TAATTCAGCACTAGTGGAGTTATCTGATGTTTTATCAGGTCATTTTATTAACGAAAAACGTTTTTTATTAGATGTAACAG
TACAACGCTATAACAAACTGATCAGATTAGGTAGTGCTATTAATGAAGTTATTTTACATACAAACACAATTAGAGATATG
ATTGAATTTGAGTTATATATTGATGATAATTTTATTTTTTCACAGAGATCTGATGGTTTAATTATTTCCACTCCAACTGG
ATCAACCGCATATGCTTTATCTGCTGGAGGACCTATTCTTAGTCCTACAGTAGATGCTATTTTATTAGTACCAATATGCC
CTCATACTTTGTCATCTCGGCCAGTTGTGATTAATAGTAAAAGTATAATTTGTCTGAAATTTTCTAAAGTAACATCTGAA
TTGAAAATAGGTTATGATAACCAAACTCCTGTTTTGGTATGCAAAGAAGAGGAGATCTTTATTAAACGTAGTAATCATTA
TCTTGATTTGATTCATCCTAATAATTATAACTATTTTAAGACGCTAAATATTAAGCTTGGTTGGTCACAAAATATTGCTG
AAACGAAAAAATAA

Upstream 100 bases:

>100_bases
TTTTATAATTCAGTTATTATAAGGATGAATAACAGGTATTCAAGACATCATTTATTATGAATAAAAGTTATAACAAAAAC
AGAAAGGATTCAATAATAAT

Downstream 100 bases:

>100_bases
TATTGTATTGATAATTACAACAAAAAAGATAATAGTTGTAATTAAACAATAATATATTTTACATTGTATTTGAAAAGTAG
ATTAAGCAGAAAATTATGTA

Product: inorganic polyphosphate/ATP-NAD kinase

Products: NA

Alternate protein names: Poly(P)/ATP NAD kinase

Number of amino acids: Translated: 297; Mature: 296

Protein sequence:

>297_residues
MTSSIFRTIGIIGYSRHPKAVHTYDILYHWLYSKGITVIIEHHAASLLNVQKAVVGDLNDIGNYADLAIVIGGDGNMLRA
ANILAQHDIKVIGINRGTLGFLTDLDPNSALVELSDVLSGHFINEKRFLLDVTVQRYNKLIRLGSAINEVILHTNTIRDM
IEFELYIDDNFIFSQRSDGLIISTPTGSTAYALSAGGPILSPTVDAILLVPICPHTLSSRPVVINSKSIICLKFSKVTSE
LKIGYDNQTPVLVCKEEEIFIKRSNHYLDLIHPNNYNYFKTLNIKLGWSQNIAETKK

Sequences:

>Translated_297_residues
MTSSIFRTIGIIGYSRHPKAVHTYDILYHWLYSKGITVIIEHHAASLLNVQKAVVGDLNDIGNYADLAIVIGGDGNMLRA
ANILAQHDIKVIGINRGTLGFLTDLDPNSALVELSDVLSGHFINEKRFLLDVTVQRYNKLIRLGSAINEVILHTNTIRDM
IEFELYIDDNFIFSQRSDGLIISTPTGSTAYALSAGGPILSPTVDAILLVPICPHTLSSRPVVINSKSIICLKFSKVTSE
LKIGYDNQTPVLVCKEEEIFIKRSNHYLDLIHPNNYNYFKTLNIKLGWSQNIAETKK
>Mature_296_residues
TSSIFRTIGIIGYSRHPKAVHTYDILYHWLYSKGITVIIEHHAASLLNVQKAVVGDLNDIGNYADLAIVIGGDGNMLRAA
NILAQHDIKVIGINRGTLGFLTDLDPNSALVELSDVLSGHFINEKRFLLDVTVQRYNKLIRLGSAINEVILHTNTIRDMI
EFELYIDDNFIFSQRSDGLIISTPTGSTAYALSAGGPILSPTVDAILLVPICPHTLSSRPVVINSKSIICLKFSKVTSEL
KIGYDNQTPVLVCKEEEIFIKRSNHYLDLIHPNNYNYFKTLNIKLGWSQNIAETKK

Specific function: Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus

COG id: COG0061

COG function: function code G; Predicted sugar kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD kinase family

Homologues:

Organism=Homo sapiens, GI55743112, Length=194, Percent_Identity=32.9896907216495, Blast_Score=82, Evalue=5e-16,
Organism=Escherichia coli, GI1788968, Length=287, Percent_Identity=57.1428571428571, Blast_Score=346, Evalue=9e-97,
Organism=Saccharomyces cerevisiae, GI6320794, Length=245, Percent_Identity=30.2040816326531, Blast_Score=113, Evalue=3e-26,
Organism=Saccharomyces cerevisiae, GI6325068, Length=199, Percent_Identity=34.6733668341709, Blast_Score=111, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6322509, Length=250, Percent_Identity=29.6, Blast_Score=111, Evalue=1e-25,
Organism=Drosophila melanogaster, GI28573828, Length=184, Percent_Identity=34.7826086956522, Blast_Score=85, Evalue=7e-17,
Organism=Drosophila melanogaster, GI28573832, Length=231, Percent_Identity=33.3333333333333, Blast_Score=85, Evalue=7e-17,
Organism=Drosophila melanogaster, GI28573826, Length=184, Percent_Identity=34.7826086956522, Blast_Score=84, Evalue=8e-17,
Organism=Drosophila melanogaster, GI161077047, Length=231, Percent_Identity=33.3333333333333, Blast_Score=84, Evalue=8e-17,
Organism=Drosophila melanogaster, GI28573830, Length=184, Percent_Identity=34.7826086956522, Blast_Score=84, Evalue=8e-17,
Organism=Drosophila melanogaster, GI24653424, Length=209, Percent_Identity=30.622009569378, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24653422, Length=209, Percent_Identity=30.622009569378, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI281363323, Length=209, Percent_Identity=30.622009569378, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI20129957, Length=209, Percent_Identity=30.1435406698565, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI281363321, Length=209, Percent_Identity=30.622009569378, Blast_Score=78, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PPNK_BLOPB (Q492C6)

Other databases:

- EMBL:   CP000016
- RefSeq:   YP_278052.1
- ProteinModelPortal:   Q492C6
- SMR:   Q492C6
- STRING:   Q492C6
- GeneID:   3563130
- GenomeReviews:   CP000016_GR
- KEGG:   bpn:BPEN_565
- eggNOG:   COG0061
- HOGENOM:   HBG713904
- OMA:   FESFMID
- ProtClustDB:   PRK03378
- BioCyc:   CBLO291272:BPEN_565-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00361
- InterPro:   IPR016064
- InterPro:   IPR017438
- InterPro:   IPR017437
- InterPro:   IPR000595
- InterPro:   IPR002504
- Gene3D:   G3DSA:2.60.200.30
- Gene3D:   G3DSA:3.40.50.10330
- PANTHER:   PTHR20275

Pfam domain/function: PF01513 NAD_kinase; SSF111331 ATP-NAD_kinase_PpnK-typ

EC number: =2.7.1.23

Molecular weight: Translated: 33049; Mature: 32917

Theoretical pI: Translated: 7.38; Mature: 7.38

Prosite motif: PS50042 CNMP_BINDING_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSSIFRTIGIIGYSRHPKAVHTYDILYHWLYSKGITVIIEHHAASLLNVQKAVVGDLND
CCHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHCCEEEEEECHHHHHHHHHHHHHCCHHH
IGNYADLAIVIGGDGNMLRAANILAQHDIKVIGINRGTLGFLTDLDPNSALVELSDVLSG
CCCCEEEEEEECCCCCEEHHHHHHHHCCEEEEEECCCCEEEEEECCCCCCEEEEHHHHCC
HFINEKRFLLDVTVQRYNKLIRLGSAINEVILHTNTIRDMIEFELYIDDNFIFSQRSDGL
CEECCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEECCCEEEECCCCCE
IISTPTGSTAYALSAGGPILSPTVDAILLVPICPHTLSSRPVVINSKSIICLKFSKVTSE
EEECCCCCEEEEEECCCCCCCCCCCEEEEEEECCCCCCCCCEEEECCEEEEEEECCCCCE
LKIGYDNQTPVLVCKEEEIFIKRSNHYLDLIHPNNYNYFKTLNIKLGWSQNIAETKK
EEECCCCCCCEEEEECCEEEEEECCCEEEEEECCCCCEEEEEEEEECCCCCCHHCCC
>Mature Secondary Structure 
TSSIFRTIGIIGYSRHPKAVHTYDILYHWLYSKGITVIIEHHAASLLNVQKAVVGDLND
CHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHCCEEEEEECHHHHHHHHHHHHHCCHHH
IGNYADLAIVIGGDGNMLRAANILAQHDIKVIGINRGTLGFLTDLDPNSALVELSDVLSG
CCCCEEEEEEECCCCCEEHHHHHHHHCCEEEEEECCCCEEEEEECCCCCCEEEEHHHHCC
HFINEKRFLLDVTVQRYNKLIRLGSAINEVILHTNTIRDMIEFELYIDDNFIFSQRSDGL
CEECCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEECCCEEEECCCCCE
IISTPTGSTAYALSAGGPILSPTVDAILLVPICPHTLSSRPVVINSKSIICLKFSKVTSE
EEECCCCCEEEEEECCCCCCCCCCCEEEEEEECCCCCCCCCEEEECCEEEEEEECCCCCE
LKIGYDNQTPVLVCKEEEIFIKRSNHYLDLIHPNNYNYFKTLNIKLGWSQNIAETKK
EEECCCCCCCEEEEECCEEEEEECCCEEEEEECCCCCEEEEEEEEECCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA